Drug Study

DRUG NAME ACTION INDICATION/ CONTRA ADVERSE NURSING

RATIONALE INDICATIO EFFECTS CONSIDERATION
N
Generic Name: Like all To treat Hyper CNS: Chills, Use cephalexin
Cephalexin cephalosporins, genitourinary sensitivity to fever, cautiously in patients
cephalexin tract infections cephalexin, headache, hypersensitive to
Brand Name: interferes with caused by other seizures penicillin because cross-
Keflex bacterial cell Escherichia coli, cephalosporins CV: Edema sensitivity occurs in
wall synthesis Klebsiella , or their GI: about 10% of them.
Clasification:anti by inhibiting pneumoniae, or components Abdominal
biotic the final step in P. mirabilis; and cramps, Obtain culture and
the cross- skin and skin diarrhea, sensitivity test results, if
Dose and linking of structure elevated liver possible and as ordered,
Frequency: peptidoglycan infections caused enzymes, before giving drug.
strands. by S. aureus or S. hepatic
Tablet: 500mg Peptidoglycan pyogenes failure, Assess patient’s bowel
makes the cell hepatomegaly, pattern daily; severe
membrane rigid nausea, diarrhea may indicate
and protective. pseudomembr pseudomembranous
Without it, anous colitis, colitis caused by
bacterial cells vomiting GU: Clostridium difficile. If
rupture and die. Elevated BUN diarrhea occurs, notify
This level, prescriber and expect to
mechanism of nephrotoxicity withhold cefotaxime and
action is most , renal failure, treat with electrolytes,
effective vaginal fluids, protein, and an
against bacteria candidiasis antibiotic effective
that divide against C. difficile.
rapidly,
including many
gram-positive
and gram-
negative
bacteria.
DRUG ACTION INDICATION/ CONTRAINDICA ADVERSE NURSING
NAME RATIONALE TION EFFECTS CONSIDERATION
Generic Anti- General: CNS: Before:
Name: inflammatory; > relief of moderate headache, > Check doctor’s
Mefenamic analgesic, and pain when therapy Contraindicated with dizziness, order
acid antipyretic will not exceed 1 wk hypersensitivity to insomnia > Assess pain score
activities > treatment of mefenamic acid, > Assess for history
Brand related to primary aspirin allergy, and Dermatologic: of allergies to
Name: inhibition of dysmenorrhea as treatment of rash, pruritus, NSAIDs
Ponstel prostaglandin perioperative pain sweating > Educate patient
Clasification: synthesis; with coronary artery regarding desired
Analgesic, exact bypass grafting GI: nausea, and adverse effects
antipyretic mechanisms GI pain,
of action are Patient’s actual diarrhea, During:
Dose and not known. indications: Precaution: constipation > Give drug with
Frequency: Mefenamic acid is Use cautiously with food, milk or
Patient’s given to patient for asthma, renal or GU: dysuria, antacids
dose: relief of acute to hepatic impairment, renal > Administer drug
500mg q6o moderately severe peptic ulcer disease, impairment with full glass of
prn Onset: varies pain GI bleeding, water
hypertension, heart > Do not break,
Maximum Peak: 2-4 hr failure, pregnancy, shock chew or crush
dose: lactation capsule and tablet
500 mg Duration: 6 hr > Do not administer
with anticoagulants
Minimum Metabolism: and other drug that
dose: hepatic, 2-4 causes GI upset
125 mg hr
After:
Availability: Distribution: > Document
Capsules – crosses accordingly
250mg placenta, > Monitor for
enters breast adverse effects
milk
Route:
PO Excretion:
feces, urine
DRUG ACTION INDICATION/ CONTRA ADVERSE NURSING
NAME RATIONALE INDICATION EFFECTS CONSIDERATION
Generic Interferes It is given before Hypersensitivit GU: Elevated BUN Obtain culture and
Name: with bacterial some surgical y to level, nephrotoxicity, sensitivity results, if
cefuroxime cell wall operations, to cefuroxime, renal failure, vaginal possible and as
synthesis by prevent an other candidiasis ordered, before
Brand Name: inhibiting the infection from cephalosporins, giving drug.
ceftin final step in occurring. or their
the cross- Cefuroxime treats components Other: Anaphylaxis; Give oral form with
Clasification: linking of an infection by injection-site edema, food to decrease GI
antibiotic peptidoglycan killing the bacteria pain, and redness; distress, as needed.
strands. that are causing it. superinfection
Dose and Peptidoglycan
Frequency: makes the cell Assess bowel pattern
Tablet 500mg membrane daily; severe
PO rigid and diarrhea may
protective. indicate
Without it, pseudomembranous
bacterial cells colitis. If it’s
rupture and suspected, stop drug,
die. as ordered, and
provide treatment as
prescribed.
 DRUG ACTION INDICATION/ CONTRA ADVERSE NURSING
NAME RATIONALE INDICATION EFFECTS CONSIDERATION
Generic Acts to normalize Hemochromatosis, Give iron tablets and
Name: RBC production To prevent iron hemolytic GI: Abdominal capsules with a full
ferrous by binding with deficiency based anemias, cramps, glass of juice or
sulfate hemoglobin or by on recommended hemosiderosis, constipation, water. Don’t crush
being oxidized daily allowances hypersensitivity to epigastric pain, enteric-coated tablets
Brand and stored as iron salts or their nausea, stool or open capsules.
Name: hemosiderin or components, other discoloration,
Feosol aggregated ferritin anemic conditions vomiting
in unless If GI irritation
Clasification: reticuloendothelial accompanied by occurs, give with or
Antianemic, cells of the bone iron deficiency just after meals.
nutritional marrow, liver, and Protect liquid form
supplement spleen. Iron is an from freezing.
essential
Dose and component of
Frequency: hemoglobin,
Pregnant myoglobin, and
women. 27 several enzymes,
mg daily including catalase,
Oral cytochromes, and
peroxidase. Iron is
needed for
catecholamine
metabolism and
normal neutrophil
function.
DRUG NAME ACTION INDICATION/ CONTRA ADVERSE NURSING
RATIONALE INDICATION EFFECTS CONSIDERATION
Generic Name: Antipyretic:  Contraindicated  Hypersensitivity:  Do not exceed the
paracetamol Reduces Temporary with allergy to rash, fever recommended
fever by reduction of acetaminophen dosage.
Brand Name: acting fever,  Use cautiously  Avoid using
directly on multiple
Tylenol temporary relief with
the preparations
Clasification: hypothalamic of minor aches pregnancy, containing
Analgesic(nonopioid) heat- and pains lactation acetaminophen.
Antipyretic regulating Carefully check all
center to OTC products.
Dose and cause  Give drug with
Frequency: vasodilation food if GI upset
500mg/tab and occurs.
sweating,  Discontinue drug
PRN not exceeding which helps if hypersensitivity
dissipate reactions occur.
3900mg/day
heat.