Gujarat Technological University

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Seat No.: ________ Enrolment No.

___________

GUJARAT TECHNOLOGICAL UNIVERSITY


BE - SEMESTER–VII (NEW) EXAMINATION – WINTER 2021
Subject Code:3170407 Date:10/12/2021
Subject Name:Biochemical Engineering
Time:10:30 AM TO 01:00 PM Total Marks: 70
Instructions:
1. Attempt all questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
4. Simple and non-programmable scientific calculators are allowed.

MARKS

Q.1 (a) Give an example of work domains of Bioengineer and Biomedical 03


Engineer.
(b) Define Respiratory quotient and Yield. Explain in brief. 04
(c) Exemplify the heat of reaction and heat of combustion. What is 07
Enthalpy?

Q.2 (a) Enlist an example of Bingham and Casson body fluids. 03


(b) How do you sterilize the air in fermentation system? 04
(c) How would you enhance the mixing process? 07
OR
(c) Explain the effect of shear force on the process of mixing. Suggest 07
the operational steps to run it economically.

Q.3 (a) What is scale up process? 03


(b) When is the need for scale down process? 04
(c) Explain the reaction kinetics for biological systems. 07
OR
Q.3 (a) Enlist the multiphase bioreactors. 03
(b) What is Chemo-state reactor? Does it work better with immobilized 04
cells? Give your comments.
(c) Derive suitable equation for the kinetics of cell death. Define the 07
order of the equation and explain the parameters.

Q.4 (a) What are the elements in Biosensors? 03


(b) Explain the uses of Mass spectrometry. 04
(c) Write notes on: [1] Sparger design and [2] Evaporation Control. 07
OR
Q.4 (a) What is the role of dispersion in FIA? 03
(b) Enlist the online and offline monitoring system. 04
(c) Give your points on difference in reactor technology while 07
treatments of animal and plant cells,
Q.5 (a) Define: Deterministic and stochastic models. 03
1
(b) From point of view of Economy, which downstream operation 04
would you choose for high molecular protein separation (including
purification) ? And Why?

(c) Explain any one method to find the Mass transfer coefficient. 07
OR
Q.5 (a) When can you use Lineweaver-Burke Plot? 03
(b) What is the scenario for working capital and fixed capital in Biotech 04
industries?
(c) Give an elaborate view on types of models. Explain each of them in 07
brief.

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