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    Lab 4 (1) Solution

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    Rachael
    The document contains sample data from clinical trials and studies including minutes from a weekly exercise meeting, blood pressure readings before and after medication, a clinical trial comparing a new blood pressure medication to a placebo, frequencies of reported symptoms from an experimental vs placebo treatment, hypertensive status by clinical trial site, PEF measurements from subjects with and without chronic bronchitis, and interpretation of results sections.

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    Lab 4 (1) Solution

    Uploaded by

    Rachael
    18 views11 pages
    The document contains sample data from clinical trials and studies including minutes from a weekly exercise meeting, blood pressure readings before and after medication, a clinical trial comparing a new blood pressure medication to a placebo, frequencies of reported symptoms from an experimental vs placebo treatment, hypertensive status by clinical trial site, PEF measurements from subjects with and without chronic bronchitis, and interpretation of results sections.

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    Lab 4 (1) solution

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    The document contains sample data from clinical trials and studies including minutes from a weekly exercise meeting, blood pressure readings before and after medication, a clinical trial comparing a new blood pressure medication to a placebo, frequencies of reported symptoms from an experimental vs placebo treatment, hypertensive status by clinical trial site, PEF measurements from subjects with and without chronic bronchitis, and interpretation of results sections.

    Copyright:

    © All Rights Reserved
    Download as XLSX, PDF, TXT or read online from Scribd
    Download as xlsx, pdf, or txt
    18 views11 pages

    Lab 4 (1) Solution

    Uploaded by

    Rachael
    The document contains sample data from clinical trials and studies including minutes from a weekly exercise meeting, blood pressure readings before and after medication, a clinical trial comparing a new blood pressure medication to a placebo, frequencies of reported symptoms from an experimental vs placebo treatment, hypertensive status by clinical trial site, PEF measurements from subjects with and without chronic bronchitis, and interpretation of results sections.

    Copyright:

    © All Rights Reserved
    Download as XLSX, PDF, TXT or read online from Scribd
    Download as xlsx, pdf, or txt
    of 11

    Minutes of Weekly Exercise Sample Data

    n 40
    Mean 175 Z=x-µ
    SD 19.5 s/√n

    Population
    Mean 191

    Z -5.189378724
    p-value 0.0000001
    Back Side Sitting Standing
    140 141 144 147
    144 143 145 145
    146 145 147 148
    141 144 148 149
    139 136 144 145
    Systolic Blood Presure with new medication
    Baseline 4 Weeks
    120 122
    145 142
    130 135
    160 158
    152 155
    143 140
    126 130
    Clinical Trial for new blood pressure medication
    Experimental Placebo
    125 145
    130 140
    135 132
    121 129
    140 145
    137 150
    129 160
    145 140
    115 120
    Change in Symptoms by Treatment--Observed Frequencies
    Change in Symptoms
    Treatment Much worse Worse No Change Better Much Better Total
    Experimental 10 17 35 28 10
    Placebo 12 25 42 12 9
    Total

    χ2 Calculations
    Much worse Worse No change Better Much better
    Experimental
    Placebo

    df
    chi squared
    p-value
    Change in Symptoms by Treatment--Expected Frequencies
    Change in Symptoms
    Treatment Much worse Worse No Change Better Much Better Total
    Experimental
    Placebo
    Total
    Standard Treatment Placebo New treatment
    124 134 114
    111 143 117
    133 148 121
    125 142 124
    128 150 122
    115 160 128

    Interpretation of
    Results
    Treatment Placebo
    Pre Post Pre Post
    2 5 6 10
    14 19 6 8
    10 16 2 3
    16 15 15 15
    10 9 8 6
    6 10 6 10
    1 2 20 20
    9 12 3 5
    9 12 13 17
    11 17 10 16
    10 12 10 8
    5 6 14 15
    2 3 2 5
    3 2 21 25
    6 10 7 12
    8 11 12 20
    4 3 8 10
    8 10

    Interpretation of
    Results
    Hypertensive Status by Clinical Trial Site--Observed Hypertensive Status by Clinical Trial Site--Observed
    Site Site
    Hypertensive 1 2 3 Total Hypertensive 1 2 3 Total
    Yes 17 23 35 Yes
    No 83 77 65 No
    Total Total

    Hypertensive 1 2 3
    Yes
    No

    Chi-squared
    p-value

    Interpretation of
    Results
    Sample Data
    n 40
    Mean 279
    SD 71

    Population Mean 306

    Z
    p-value

    Interpretation of
    Results
    PEF (L/min)
    Subject Chronic Bronchitis Healthy Children
    1 281 360
    2 274 372
    3 305 295
    4 366 382
    5 315 234
    6 224 275
    7 192 286
    8 229 304
    9 276 333
    10 315 401
    11 184 212
    12 287 312
    13 264 324
    14 296 296
    15 301 378
    16 327 384
    17 350 271
    18 311 299
    19 253 371
    20 285 305

    Interpretation of
    Results

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