1-2 Prelim - Introduction To Parasitology

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Parasitology

➢ the area of biology concerned with the


phenomenon of dependence of one living
organism on another.
Medical Parasitology
➢ is concerned primarily with the animal
parasites of humans and their medical
significance, as well as their importance in
human communities.
Parasite
➢ Organism depending on another living
creatures for existence
Host
➢ Organism that supports or harbors parasite
Vector
➢ are responsible for transmitting the parasite
from one host to another.
Incidence
➢ number of new cases of infection in a
population in a given period of time.
Exposure
➢ the act or process of inoculation.
Pathogen
➢ animal parasites which are harmful,
frequently causing local and systemic
damage of one type or another.
Incubation period
➢ Period between infection and evidence
of symptoms
➢ Pre-patent period
➢ Biologic incubation period
Superinfection
➢ when an individual harboring a
parasite is reinfected with the same
specie of parasites.
Autoinfection
➢ when the infected person is his own
direct source of reexposure.
1. Mechanical / Phoretic Vector
➢ the parasite is only seen on the surface
of this organism and there will be no
development on the parasite
➢ eg. Cockroaches, flies
2. Biological Vector
➢ the parasite is seen inside the body of
this organism and the parasite needs
this organism for its development
➢ eg. Mosquitoes, tsetse flies
1. Obligate parasite
➢ depend entirely upon their host for
existence.
2. Facultative parasite
➢ exist in a free-living state or may become
parasitic when the need arises.
3. Incidental / Accidental parasite
➢ attack an unusual host
4. Spurious parasite
➢ free-living organisms in nature that are
parasitic to others but not in human.
1. Ectoparasite
➢ parasite living outside the body of the host
➢ will not penetrate into the tissues.
➢ living on the surface of the skin
➢ the caused of these are called as infestation

2. Endoparasite

➢ parasite living inside the body of the host


➢ living within the body of the host (infection)
➢ usually these are responsible to cause human infections.

3. Saprophytes
➢ that which lives in organic substances in state of
decomposition.
TYPES OF HOST
DEFINITION/DESCRIPTION
Accidental host host other than the normal one that is harboring a parasite
Definitive host host in which the adult sexual phase of parasite
development occurs
Reservoir host host harboring parasites that are parasitic for humans and
form which humans may become infected
Intermediate host host in which the larval asexual phase of parasite
development occurs
Transport host host responsible for transferring a parasite from one location
to another
Carrier parasite harboring host that is not exhibiting any clinical
symptoms but can infect others
Parasite-host relationship
DEFINITION/DESCRIPTION
Symbiosis living together; the association of two living organisms,
Commensalism association of two different species of organisms that is
beneficial to one and neutral to other
Mutualism association of two different species of organism that is
beneficial to both
Parasitism association of two different species of organisms that is
beneficial to one at the other’s expense
Commensalism relating to commensalism; the association between two
different organisms in which one benefits and has a neutral
effect on the other
Pathogenic parasite that has demonstrated the ability to cause disease
commensalism symbiosis

parasitism
1. Ingestion of contaminated food or drink (primarily
water)
EXAMPLE: CYST OF
- E.histolytica
- G.lamblia
2. Hand-to-mouth transfer
EXAMPLE: EGGS OF
- A. lumbricoides
- T. trichiura
3. Insect bite
EXAMPLE: - W. bancrofti
- B. malayi
4. Entry via drilling through the skin

EXAMPLE: - Schistosoma sp.

- Hookworm

5. Unprotected sexual relations

EXAMPLE: - T. vaginalis

6. Mouth-to-mouth contact

EXAMPLE: - T. tenax
7. Eating raw or inadequately cooked foods
- EXAMPLE: - E.ilocanum ( nails )
- C.philippinensis ( fish )
- D.latum ( fish )
- T.saginata ( beef )
- T.solium ( pork )
8. Domestic animals
- EXAMPLE: - D.caninum
- H.diminuta
1. Portal of entry
➢ particular site of the body where the
parasite prefer to enter.
2. Portal of exit
➢ site of the body where the parasite moves
out
I. MOUTH
II. SKIN
III. PERCUTANEOUS
IV. INHALATION
V. SECRETIONS
VI. SEXUALLY
TRANSMITTED
I. Mouth - A.lumbricoides
- T.trichuria
- E.vermicularis
- E.histolytica
- G.lamblia
- C.philippinensis
II. SKIN - N.americanus
- A.duodenale
- S.stercolaris
- S.japonicum

III. PERCUTANEOUS
- Malarial parasites
- Filarial worms
- Leishmania
- Trypanosomes
IV. INHALATION - E.vermicularis

V. SECRETIONS - S.stercolaris
- Ancylostoma spp.
VII. SEXUALLY
TRANSMITTED - T.vaginalis
• Parasitic life cycle range from simple to
complex, they all have three common
components
❑ Mode of transmission
❑ morphologic form that invades humans
❑ forms that can be detected via laboratory retrieval
methods
• Some parasites require only 1 definitive host,
whereas others also require 1 or more
intermediate host
• A parasite life cycle consist of two common
phases
• Individuals in underdeveloped areas and countries
• Refugees
• Immigrants
• Visitors from foreign countries
• Individuals who are immunocompromised
• Individuals living in close quarters (e.g., prisons)
• Children who attend day care centers
• Chemotherapy
• Surgical intervention – if chemotherapy is
unavailable or has proved inadequate.
• The following points must be considered:
• Severity, duration and intensity of
infection and the probability of reinfection.
• Efficacy, availability, toxicity and
acceptability of the treatment.
• Development and implementation of parasite
awareness
• education programs
• Use of insecticides and other chemicals
• Use of protective clothing
• Use of protective netting
• Proper water treatment
• Good personal hygiene
• Proper sanitation practices
• Proper handling, cooking, and protection of food
• Avoidance of unprotected sexual relations
Sub Phylum Sub-phylum Genus- Species-
kingdom examples examples

Protozoa Sarcomastig- Sarcodina-- - Entamoeba E. histolytica


ophora move by
pseudopodia
further divided into

Mastigophora Giardia G. lamblia


move by flagella

Apicomplexa Plasmodium P. falciparum,


no organelle of P. vivax,
locomotion
P. malariae,
P. ovale

Ciliophora Balantidium B. coli


move by cillia

Microspora Enterocyto- E. bienusi


Spore-forming zoa
Sub Phylum Class Genus –
kingdom examples
Metazoa Nematodes Ascaris (roundworm)
Round worms; appear round Trichuris (whipworm)
in cross section, they have Ancylostoma (hookworm)
body cavities, a straight Necator (hookworm)
alimentary canal and an Enterobius (pinworm or
anus threadworm)
Strongyloides

Platyhelminthes Cestodes Taenia (tapeworm)


Flat worms; dorsoventrally Adult tapeworms are found in
flattened, no body cavity the intestine of their host
and, if present, the They have a head (scolex) with
alimentary canal is blind sucking organs, a segmented
ending body but no alimentary canal
Each body segment is
hermaphrodite

Trematodes Fasciolopsis (liver fluke)


Non-segmented, usually leaf- Schistosoma (not leaf
shaped, with two suckers but shaped!)
no distinct head
They have an alimentary canal
and are usually hermaphrodite
and leaf shaped
Schistosomes are the
exception. They are thread-
like, and have separate sexes

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