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    Inhibit Classification Antibiotics

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    Nurnaningsi Tajuddin Thalib
    This document provides information on common pathogens found in surgical patients and summarizes various classes of antibiotics and antifungal agents used to treat infections. It lists many common bacteria that can cause infections including Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, anaerobic bacteria like Bacteroides fragilis, and various fungi such as Candida albicans. The document then categorizes different classes of antibiotics like penicillins, cephalosporins, carbapenems, and antifungal agents including azoles, echinocandins, and amphotericin B, noting their advantages and disadvantages.

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    Inhibit Classification Antibiotics

    Uploaded by

    Nurnaningsi Tajuddin Thalib
    89 views5 pages
    This document provides information on common pathogens found in surgical patients and summarizes various classes of antibiotics and antifungal agents used to treat infections. It lists many common bacteria that can cause infections including Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, anaerobic bacteria like Bacteroides fragilis, and various fungi such as Candida albicans. The document then categorizes different classes of antibiotics like penicillins, cephalosporins, carbapenems, and antifungal agents including azoles, echinocandins, and amphotericin B, noting their advantages and disadvantages.

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    Antibiotik, Fungi

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    This document provides information on common pathogens found in surgical patients and summarizes various classes of antibiotics and antifungal agents used to treat infections. It lists many common bacteria that can cause infections including Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, anaerobic bacteria like Bacteroides fragilis, and various fungi such as Candida albicans. The document then categorizes different classes of antibiotics like penicillins, cephalosporins, carbapenems, and antifungal agents including azoles, echinocandins, and amphotericin B, noting their advantages and disadvantages.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    89 views5 pages

    Inhibit Classification Antibiotics

    Uploaded by

    Nurnaningsi Tajuddin Thalib
    This document provides information on common pathogens found in surgical patients and summarizes various classes of antibiotics and antifungal agents used to treat infections. It lists many common bacteria that can cause infections including Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, anaerobic bacteria like Bacteroides fragilis, and various fungi such as Candida albicans. The document then categorizes different classes of antibiotics like penicillins, cephalosporins, carbapenems, and antifungal agents including azoles, echinocandins, and amphotericin B, noting their advantages and disadvantages.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    of 5

    INHIBIT CLASSIFICATION ANTIBIOTICS

    Penicinillase-Sensible
    Natural Penicillin G: Na K, Procainic, Benzathine (IV,IM)
    Penicillins Penicillin V:VO
    (narrow
    spectrum)
    Cell
    Aminopenicil Ampicillin
    Wa
    lins (broad Amoxicillin
    ll Penicillins
    spectrum)
    S Penicinillase-Resistant (very narrow spectrum)
    Y Nafcillin Oxacillin Dicloxacillin
    Antipseudomonal (extended spectrum)
    N Carbocy- Ticarcillin
    T Beta penicillins Carbenicillin
    H Lactams Ureido- Piperacillin
    E penicillins Azlocillin
    S Mezlocillin
    1* Generation Cefazolin Cephalexine Cephapirin
    I Cefadroxil Cephadrine Cephalotine
    S Cefuroxime Cefamandole Cefprozil
    Cefoxitin Cefonicid Cefmetazole
    2* Generation
    Cefotetan Cefactor
    Cefoperazone Ceftriaxone Ceftazidime
    Cefpodoxime Ceftizoxime Cefotaxime
    3* Generation
    Cefdinir Ceftibuten Cefixime
    Cefditoren
    Cephalosporin 4* Generation Cefepime Cefpirome*
    5* Generation Ceftaroline
    Carbapenems Meropenem Ertapenem Doripenem Imipenem +
    Cylastatine
    Monobactams Aztreonam
    Beta-lactamase inhibitor Sulbactam Tazobactam Clavulanic Acid
    No Glycopeptides Vancomycin Bacitracin
    Teicoplanin Polymixin B
    Lactam
    Gentamycin Neomycin Streptomycin
    Aminoglycosides
    305 Amikasin Tobramycin
    Doxycycline Demeclocylin Monocycline
    Protein Tetracycline Tigecyclin
    Tetracyclins
    Synthesis Oxazolidanones Linezolid
    Streptogramins Quinupristin/Dalfopristin
    Cloramphenicol
    505 Macrolides Erythromicin Azithromycin Clarithromycin
    Lincosamides Clindamycin Lincomycin
    Fluor- Ciprofloxacin Norfloxacin Levofloxacin Ofloxacin
    Sparfloxacin Moxifloxacin Gemifloxacin Enofloxacin
    DNA quinolones
    Quinolones Nalidixic Acid
    topoisomerases
    Sulfametho- Ag Sulfasalazine Sulfisoxazole
    Folic Acid Sulfonamides xazole (SMX) Sulfadiazine
    Synthesis DHFR Trimetoprim (TMP) Pirymethamine
    Inhibitors
    DNA (damage) Metronidazole
    mRNA synth. Rifampim

    COMON PATHOGENS IN SURGICAL PATIENTS

    Gram-positive Aerobic Cocci


    Staphylococcus aureus
    Staphylococcus epidermidis
    Streptococcus pyogenes
    Streptococcus pneumoniae
    Enterococcus faecium, E faecalis
    Gram-negative Aerobic Bacili
    Eschericia coli
    Haemophilus influenzae
    Klebsiella pneumoniae
    Proteus mirabilis
    Enterobacter cloacae, E aerogenes
    Serratia marcescens
    Acinetobacter calcoasceticus
    Citrobacter freundii
    Pseudomonas Aeruginosa
    Stenotrophomonas maltophilia
    Anaerobes
    Gram-positive
    Clostridium difficile
    Clostridium perfringens, C tetani, C septicum
    Peptostreptococcus spp.
    Gram-negative
    Bacteroides fragilis
    Fusobacterium spp
    Other bacteria
    Mycobacterium avium-intracellulare
    Mycobacterium tuberculosis
    Nocardia asteroids
    Legionella pneumophila
    Listeria monocytogenes
    Fungi
    Aspergillus fumigatus, A niger, A terreus, A flavus
    Blastomyces dermatitidis
    Candida albicans
    Candida glabrata, C paropsilosis, C krusei
    Coccidiodes immitis
    Cryptococcus neoformans
    Histoplasma capsulatum
    Mucor/Rhizopus
    Viruses
    Cytomegalovirus
    Epstein-Barr virus
    Hepatitis A, B, C viruses
    Herpes simplex virus
    Human immunodeficiency virus
    Varicella zooster virus

    Antifungal Agents and Their Characteristics

    ANTIFUNGAL ADVANTAGES DISTADVANYAGES


    Amphotericin B Broad spectrum, Renal toxicity, premed, IV
    inexpensive only
    Liposomal Broad-spectrum Expensive, IV Only, renal
    Amphotericin B toxicity
    Azoles
    Fluconazole IV and PO availability
    Itraconazole IV and PO availability Narrow spectrum, no CSF
    penetration
    Drug interactions,
    decreased cardiac
    contractility
    Posaconazole Broad-spectrum, PO Only
    zygomycete activity
    Voriconazole IV and PO availability, IV diluent accumulates in
    Broad-spectrum renal failure, Visual
    disturbances
    Echinocandins
    Anidulofungin, Broad-spectrum IV only, poor CNS
    Caspofungin, Micafungin penetration

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