Kidney Structure and Function

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The key takeaways are that the kidney filters blood and produces urine, it has an outer cortex and inner medulla, and nephrons are the functional units that filter blood and regulate water and electrolyte balance.

The main components of a nephron are the Bowman's capsule which encloses the glomerulus, and the renal tubule which the filtered fluid passes through.

Ultrafiltration is the process where small molecules are filtered out of blood in the glomerulus into the Bowman's capsule. Reabsorption is the process where useful substances like water and glucose are absorbed back into the bloodstream from the renal tubule.

Kidney Structure and Function

Blood enters the kidney through the renal artery is filtered by the
kidney and leaves through the renal vein.

Urine leaves through the ureter and is collected in the bladder

The outer zone of the kidney is called the cortex and the inner zone
is called the medulla

If you then use a microscope and look at the cortex you begin to see
lots of structures called nephrons. There are about 750,000 of
them in each kidney.
A Nephron

At one end is a cup-like structure called the Bowman's capsule. It


encloses a knot of capillaries called the glomerulus. These capillaries
are leaky and small molecules get filtered out and end up inside the
Bowman's capsule. This process is called ultrafiltration.

If nothing else happens then the materials, such as water and urea,
will end up going all the way through the nephron, down the ureter,
through the bladder and out of the body.

However, sometimes the body needs to grab back chemicals such as


water and glucose which are still useful. This happens when they
move out of the fluid in the nephron back into the capillary network
that twists around the nephron.

This process is called reabsorption. Reabsorption means that the


useful chemicals are taken back into the blood out of the nephron.
They do not end up in the urine and are not lost by the body.
Supply the missing words in the following paragraph:

Blood is taken to the kidney in the ________ artery, which


divides up into many arterioles. The arterioles enter the_______ of
the kidney and supply thousands of glomeruli. In each glomerulus,
________ forces plasma minus its________ out of the capillaries,
and it collects in the _________This liquid passes down
the________ where __________, ___________and _________
are reabsorbed into the blood. The remaining liquid, called
_________. passes down the ____________and collects in
the___________ before being expelled from the body.

Bladder Cortex Renal Proteins Glucose Water Renal Tubule


Ureter Blood Pressure Bowman’ Capsule Salts Urine

In hot weather the urine becomes

(a) more concentrated and lighter in colour;

(b) more concentrated and darker in colour

(c) less concentrated and lighter in colour

(d) 1ess concentrated and darker in colour.

Which of the following substances would you not normally expect to


find in a sample of urine?

(a) uric acid, (b) ammonia, (c) glucose, (d) sodium chloride, (e) urea.
Answers
The missing words are (A) renal, (B) cortex, (C) blood pressure, (D) proteins, (E) Bowman's capsule
(or renal capsule), (F) renal tubule, (G) glucose, (H) salts, (I) water, (J) urine,

(K) ureter, (L) bladder.

4 (b) In hot weather, urine becomes more concentrated and darker in colour.

5 (c) You would not normally expect to find glucose in a urine sample.

The missing words are (A) renal, (B) cortex, (C) blood pressure, (D) proteins, (E) Bowman's capsule
(or renal capsule), (F) renal tubule, (G) glucose, (H) salts, (I) water, (J) urine,

(K) ureter, (L) bladder.

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