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    Phagocytes

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    Ana Perez
    The document discusses innate and acquired immunity, including phagocytes, B cells, T cells, and natural and artificial immunity. It also covers mucosal immunity, vaccines, third-degree burns, and severe combined immunodeficiency.

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    © All Rights Reserved
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    Phagocytes

    Uploaded by

    Ana Perez
    17 views3 pages
    The document discusses innate and acquired immunity, including phagocytes, B cells, T cells, and natural and artificial immunity. It also covers mucosal immunity, vaccines, third-degree burns, and severe combined immunodeficiency.

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    phagocytes immune health

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    The document discusses innate and acquired immunity, including phagocytes, B cells, T cells, and natural and artificial immunity. It also covers mucosal immunity, vaccines, third-degree burns, and severe combined immunodeficiency.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    17 views3 pages

    Phagocytes

    Uploaded by

    Ana Perez
    The document discusses innate and acquired immunity, including phagocytes, B cells, T cells, and natural and artificial immunity. It also covers mucosal immunity, vaccines, third-degree burns, and severe combined immunodeficiency.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    of 3

    Mucosal

    Immunity
    ● Innate / acquired
    Innate (genetic)= protect from birth to death
    ● External - 1st line of defense; “Earth’s ozone layer”; skin, cilia, tears, mucus, stomach
    acid, bacteria
    ● Internal defense - 2nd line of protection; fever, natural killer cells, inflammation,
    phagocytes, interferons

    Innate Immunity/Genetic/Familial

    Acquired
    - Mighties
    - 3rd line of defense
    - Against specific pathogens
    - Natural
    - Artificial
    Has passive & active (1st line?)

    Phagocytes
    - identify
    - Sent to lymphocytes; T & B cells
    - B cells & T cells use info to produce antibodies; each antigen has antibodies to destroy
    invader cells = Natural Active Immunity

    Artificial active immunity


    - Allergic reaction = extreme response; delay bet. Acquired immunity
    1st exposure
    - Primary response = faster and stronger response (secondary response)

    Passive immunity
    - Come from outside organism
    - Doesn’t require exposure from infectious agent / antigen
    - No delay
    - Natural; via breastmilk
    - Artificial; serum / antidotes
    - Not as long-lasting

    Active immunity
    - Lasts a long time
    - 1st line of defense
    Vaccines
    - RISK: Important part: be exposed to pathogen; introduce pathogen to immune system;
    after 1st exposure, eventually defenses stronger for next invasion; overexposure
    - BENEFITS: higher

    Thrombocyte
    - NOT type of leukocytes

    B cells (bone marrow) vs. T cells (thymus)


    - Site of maturity

    GROUP 5
    3rd degree burns
    ● Thermal injury; 3 layers (epidermis, dermis, hypodermis)
    ● Numb, dry, leathery; damaged nerve & blood vessels
    ● Size of a nickel
    ● Long time to heal
    ● heal w/ skin grafting (healthy skin from other body or synthetic)
    ○ Surgical debridement (remove dead tissue)
    Pathophysio
    ● Wound; worse; tiny microbes
    WBCs
    ● Lymphocytes
    ● Fight off microbes
    Immunosuppression
    ● Many 3rd degree experience this
    ● Causes:
    1. Damaged tissues & interstitial fluid contain certain substances
    2. Inactivation of non-granular leukocytes (e.g. macrophages)

    How to heal?

    Pharmacological Nutrition
    ● Most frequently used?
    ● Food high in glutamine (chicken, spanish), arginine (collagen synthesis; dairy), (N-3) fatty
    acids (phospholipid composition)
    Severe Combined Immunodeficiency
    ● Slight contact to foreign condition → fatal condition
    ● Rare & inherited
    ● B & T cells inactive/missing
    ○ WBCs for immunity
    ● For males
    ● E.g. X-linked SCID
    ○ Males BUT females can be carriers and have 50% chance of passing down
    ○ Abnormally low T &NK count
    ○ High B cells; but not active because of growth factors??
    ● ADENOSINE deaminase deficiency
    ○ Males & females
    ○ Low levels of ADA → T & B cell decline & neurological problems
    (cognitive, hearing?)
    ○ Cause necrosis ?
    ● Diagnosis:
    1. Newborn screening (detailed family history) = NO attenuated vaccinations; period of
    isolation after vaccination; recurrence of infection sin children ((ear, chickenpox,
    pneumonia, meningitis, sepsis, diarrhea, oral thrush)
    ● Treatment
    1. Bone marrow transplant (B & t cells) stem cells
    2. Enzymatic replacement therapy (deaminase?)
    3. Antibiotics (anti-viral etc.)
    4. Admin. Of immunoglobulin
    - Nutrition not much; special diets ONLY if diabetes, sensitivity, etc.
    - psychosocial support & care → Familial problems
    - Dietary interventions (feeding to intestine/stomach) = hard time absorbing nutrients
    through skin
    - Nutritional supplements (NO evidence, can be harmful)
    - Hygiene (bathing w/ soap; toothbrush, flossing)

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