Minerals

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zinc

The gastrointestinal tract is directly affected by ingested zinc, before it is distributed through
the body. Therefore, multiple gastrointestinal symptoms after oral uptake of zinc have been
reported. Brown et al. described several cases in which high zinc ingestion resulted from
storage of food or drink in galvanized containers. Ingestion was caused by the moderately
acidic nature of the food or drink, enabling the removal of sufficient zinc from the galvanized
coating. The resulting symptoms included nausea and vomiting, epigastric pain, abdominal
cramps, and diarrhea [40].
In a study by Samman and Roberts, symptoms such as abdominal cramps, vomiting and
nausea occurred in 26 of 47 healthy volunteers following ingestion of zinc sulfate tablets,
containing 150 mg elemental zinc, for six weeks [43]. However, similar doses have been used
in several other zinc supplementation studies without comparable side effects [44].
In addition to zinc sulfate, other zinc compounds like zinc oxide and zinc gluconate also have
a similar impact on the gastrointestinal system [45–47]. A 39-year-old man showed nausea,
vomiting, and abdominal pain six hours after ingesting 150 g of a 10% zinc oxide lotion, but
without signs of systemic toxicity. Furthermore, he developed gastroduodenal corrosive
injury. The symptoms persisted for three days and on the fifth day of admission, the corrosive
injury showed regression without cicatrization [47].
selenium

Nine cases of acute selenium intoxication were described by Kerdel-Vegas (1966) in persons who
had consumed nuts of the “Coco de Mono tree” (Lecythys ollaria) from a seleniferous area in
Venezuela. In most cases, nausea, vomiting, and diarrhea occurred a few hours after eating the nuts,
followed by hair loss and nail changes a few weeks after the initial episode. Most patients appeared
to make a satisfactory recovery, with eventual regrowth of hair and nails; but a 2-year-old boy died
due to severe dehydration. Samples of Brazil nuts marketed in Great Britain contained an average of
22 ppm of selenium (Thorn et al., 1978), and Chavez (1966) reported signs of selenium toxicity in
rats fed diets that included defatted Brazil nut flour containing 51 ppm of selenium. Brazil nuts
marketed in the United States also are high in selenium, with 6 percent of one sample containing
100 ppm or more (Palmer et al., 1982).

Sodium
The present study provides some evidence that high-salt diet may affect body health
by altering digestion and absorption of dietary proteins, secretion of host enzymes, and gut
microbiota composition.
Potassium

When potassium levels are high, smooth muscle contractions may be too weak to coordinate that
forward movement through the GI tract. This can lead to nausea, vomiting, and the build-up of
abdominal gas.
Gastrointestinal symptoms of hyperkalemia can include:4
Abdominal gas and bloating
Nausea
Diarrhea
Vomiting (rare)
Iron
Nausea
Vomiting’s
Constipation
Change in faecal defecation
Jaundice
abdominal pain, diarrhea,
hematemesis, and
hematochezia

magnesium
Severe overdoses of magnesium are rare in otherwise healthy people. Getting too much magnesium
from the diet is not typically a cause for concern.
Occasionally, a high dosage of magnesium from supplements or medications can cause mild
symptoms of an overdose, including diarrhea, nausea, and stomach cramps.

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