Product Introduction: Cellavision Dc-1 Loading Capacity: 1 Slide Throughput: 10 Slides/Hr Technical Specifications

🐺❣️🤺💀
Product introduction: CellaVision DC-1
● Hematology analyzer custom-designed to ● LOADING CAPACITY : 1 slide

optimize the process of performing blood ● THROUGHPUT : 10 slides/hr
cell differentials in low-volume labs ● TECHNICAL SPECIFICATIONS
○ Can be implemented stand-alone in
a small independent lab or satellite
labs
● During slide processing the analyzer

automatically locates, digitally captures
and pre-classifies cells, after which the
operator verifies and/ or modifies the
suggested classification if necessary.
● FEATURES
○ Automatically captures digital
images of cells from blood smears
○ Creates digital scan of predefined
area of any interesting specimen
○ Automate the analysis of WBCs,
RBCs, and PLTs
○ Compact design with small footprint
○ Improve efficiency, promote quality,
Improve connectivity, promote
proficiency
WORKFLOW
ANALYSIS
CELLS ANALYZED
White Blood Cells Non-WBCs

WBCs are pre-classified into twelve cell Non-WBCs are pre-classified into five categories.
categories.
Smudge, Artefacts, Giant Platelets, Platelet Clumps,

Segmented Neutrophils, Band Neutrophils, Eosinophils, Basophils, Nucleated Red Cells
Lymphocytes, Monocytes, Blast Cells, Promyelocytes, Myelocytes,
Metamyelocytes, Variant Lymphocytes, Plasma Cells
Red Blood Cells Blood Platelets

RBCs are pre-characterized based on six The software offers functionality for estimation of
morphologies. blood platelets.
Polychromasia, Hypochromasia, Anisocytosis,

Macrocytosis, Microcytosis, Poikilocytosis
PAGE VIEWS
START-UP AND LOGIN
1. Press power switch in DC 1 (Starts

automatically)
2. Login with user account to the operating

system
3. Start software by double clicking on the
“CellaVision DM Software” Icon
4. Choose database to use
5. Enter username and password
6. Click “Ok” to confirm
DAILY QC (CELL LOCATION TEST)
● Control procedures: ensure the quality of the analyzers

● Cell location test: Validates the slide preparation process and verifies the analyzer’s ability to
locate cells
● Quality of slide should be good enough for the analyzer to locate the cells needed for the
analysis
7. Use a freshly stained slide from a blood

sample with WBC count within the normal
range
8. Open the input hatch and place QC slide
into the loading tray
● Frosted slide label is positioned to
the right, blood smear is facing up
9. Apply 2 drops of immersion oil to the slide
● Hold the tip of the bottle close to
the slide without touching the slide
● Use the red color marker to find the
right position
10. Close the hatch

11. On the system control view of the software
click the slide ID field to enter the ID
12. When running daily QC the ID needs to
always start with “QC” as the first two
letter followed by an ID set up according to
laboratory guidelines
13. Click “Ok” to Confirm
14. Click the start button to start slide

processing
***The QC run starts and takes approximately 5

minutes
15. Click “Cell Location”
Verify that the analyzer has located all

nucleated cells
● Examine the overview image and counting
any cells that have not been located by the
analyzer
● Analyzer will calculate the percentage of
nucleated cells that have been nucleated
The slide that has been processed in the last QC

run is selected and the first image from the cell
location slide is opened
● Cells that have been located by the
analyzer are highlighted with a green, blue
or black frame
16. Count nucleated cells that have not been

located or marked by analyzer
automatically
17. Enter the number in “WBCs + nRBCs
Missed” text box
18. Repeat procedure with every image using

the next button
19. Under “Total Results” check the ratio of
WBCs and nRBCs found is within the
laboratory’s establish limits
● If limit is reached daily QC is invalid
20. After successful QC navigate back to the
system control view
21. Take out the QC slide
22. Remove excessive oil with tissue
***It is recommended to store QC slides so that

they can be used for potential troubleshooting
SHORT EXERCISE
SAMPLE PROCESSING
● Analyze slide and use the software to perform review & verification of the preliminary results as
given by the analyser
1. Load the slide to the analyser

2. Enter the sample ID (you can use a barcode scanner)
3. Confirm by pressing “Ok”
4. Close the hatch
5. Enter patient information (patient ID or name)
***When the DC-1 is connected to extended IPU or LIS, the patient demographics are automatically
downloaded
6. Check if the default settings of the type your analysis, in this case it is WBC and RBC, and the
numbers of WBC to be counted, match your analysis
7. Click “Start” to initiate slide processing
***You can see the progress of the analysis on the user interface
***The analysis takes approx. 3 mins depending upon the number of WBCs on the slides
8. Once the analysis is finished, you can remove the slide from the analyser
9. Click “Ok” to confirm
10. If a slide was not processed, or processed with a warning, the system will notify you in the
analysis log
11. Switch to the “DB verification View” in the toolbar
***On the left side you can find the worklist where all your unsigned samples are listed
12. Double click on the sample
WBC RBC
***There are different views available supporting 13. Navigate to the RBC overview
your workflow. They differ mainly on the number 14. Press “Use characterization” in the sidebar
of cell gallery shown simultaneously to perform characterization
15. Use the mousewheel to zoom in and out
***Recommended = start validation in the 1 WBC 16. Hold left mouse button and drag the
gallery for safe and efficient workflow picture to navigate
***Used view will be saved to the specific user

and selected automatically the next time you log
in and review the sample results
***check page 2 for the different view pages

***All WBC cell classes are listed 17. Perform the RBC grading by using the
RBC panel in the sidebar
***You can see the number of counts and
percentage ***Perform it based on your internal laboratory
grading limits
🟦 Automatic Preclassification
Color indicators:
18. Hover over the grading chart to see the
🟩 Manual Reclassification standard grading
19. Choose the respective color point to
classify
13. In this case, the first classification are

segmented neutrophils
14. Check all the cells in the gallery and if
needed, reclassify them
15. Double click a cell picture to have a closer
look in a specific cell
16. Use mousewheel to zoom in and out
17. Dragging the cell picture to the respective
group reclassifies the cell
18. Scroll all the way down to ensure that you
have looked at all the cells in this group
and a check mark beside the classification
group is shown.
19. Proceed with all cell classes. Check all cells
in their respective group and if needed
reclassify them
20. Additionally, you can add comments for WBC & RBC cell classes by using the comments icon
***Once you classified all the cells, you can sign the slide
21. Click on “Sign Slide” to start

22. Confirm by entering your username and password
23. Click “ok”
24. After validation, the sample will be removed from the worklist
25. Proceed with all the orders in the worklist
26. To review signed & unsigned samples go to database view

27. Choose one by double clicking
28. Optimize appearance of the cell pictures individually by using the image adjustment in the
toolbar
***You can adjust the red, green, and blue saturation, and the brightness
***The setting is user-specific and will be used every time once you save your personal setting
29. Define the color setting for each group WBC & RBC
30. Additionally to the shown workflow, the system provides several views to support individual
workflows
31. You can use the 2 WBC galleries to show classes side by side and reclassify them
32. Choose the dropdown menus to display the cell classes you want to show side by side
33. Click on the icon to display reference cells for the respective cell class
34. By using the right click on a specific cell you can also use the context menu to choose a cell
class
35. The system provides secondary and third suggestions to choose from on the top of the list
36. Use the workflow that is most intuitive to your needs
SHUT-DOWN
1. Wait for the current slide to be processed

or stop the slide from processing manually.
2. Navigate to the file tab on the software
and choose exit.
3. Click “Yes” to confirm.
4. Shutdown the operating system.
● The main unit will shutdown
automatically.
*** Make sure that the input hatch is closed when
the DC hatch is not used.
SHORT EXERCISE
TEST YOURSELF ANSWERS

Product Introduction: Cellavision Dc-1 Loading Capacity: 1 Slide Throughput: 10 Slides/Hr Technical Specifications

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🐺❣️🤺💀

Product introduction: CellaVision DC-1

● Hematology analyzer custom-designed to ● LOADING CAPACITY : 1 slide

● During slide processing the analyzer

White Blood Cells Non-WBCs

Smudge, Artefacts, Giant Platelets, Platelet Clumps,

Red Blood Cells Blood Platelets

Polychromasia, Hypochromasia, Anisocytosis,

1. Press power switch in DC 1 (Starts

2. Login with user account to the operating

DAILY QC (CELL LOCATION TEST)

● Control procedures: ensure the quality of the analyzers

7. Use a freshly stained slide from a blood

10. Close the hatch

14. Click the start button to start slide

***The QC run starts and takes approximately 5

Verify that the analyzer has located all

The slide that has been processed in the last QC

16. Count nucleated cells that have not been

18. Repeat procedure with every image using

***It is recommended to store QC slides so that

1. Load the slide to the analyser

12. Double click on the sample

***Used view will be saved to the specific user

***check page 2 for the different view pages

13. In this case, the first classification are

21. Click on “Sign Slide” to start

26. To review signed & unsigned samples go to database view

1. Wait for the current slide to be processed

TEST YOURSELF ANSWERS

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