Central Dogma Module For Grade 10 Science

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A.

The following is the base sequence on one strand of a DNA molecule:

AATGCCAGTGGT

1. If this strand is replicated, which of the following is the complementary strand


that is produced?

_______________________________________

2. If transcribed into an mRNA, what would be the resulting strand?

_______________________________________

3. During translation, the tRNA sequence of nucleotides arranged linearly is


_______.

_______________________________________

B. Each combination of nitrogen bases on the mRNA molecule is a codon, which is


a three letter code for a specific amino acid. The table shows the mRNA codon
for each amino acid. Use the Genetic Code Table to answer the questions.

4. The codon for tryptophan is _______.


5. For leucine, there are _______ different codons.

6. The codon GAU is for __________.

7. In a stop codon, if the second base is G, the first and third bases are

____ and ___.

C. Sequence the following steps in protein synthesis from first to last (1-6).
___A. Transcription

___B. tRNA – amino acid units link to mRNA

___C. Amino acid separate from tRNA

___D. Polypeptide chain assembled

___E. mRNA links to ribosome

___F. Stop codon encountered in mRNA

D. Each combination of three nitrogenous bases on the mRNA molecule is a codon, a


three letter code for a specific amino acid. Use the table below to identify the specific
amino acid for each mRNA codon.

III. Name the following genetic disorder.


TURNER’S SYNDROME EDWARDS SYNDROME JACOBSEN SYNDROME
DOWN’S SYNDROME CRI DU CHAT KLINEFELTER’S SYNDROME

1. _________________ 2. _________________ 3. ___________


4. ____________ 5. ______________ 6. ______________

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