Note: Topic Presentation 8 Will Be Your Guide in Answering This Activity. Answers: Gene A

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NAME: ATANGEN, KEZEL ANN D.

DATE: JULY 26, 2021


COURSE AND YEAR: BS CE, 1st YEAR TIME: 3:30PM-7:30PM

NOTE :  TOPIC PRESENTATION 8  WILL BE  YOUR GUIDE IN ANSWERING THIS


ACTIVITY.

ANSWERS:

PART 1.

GENE A
DNA: TGG   CCT  ATA
mRNA: ACC GGA UAU
tRNA:  UGG CCU AUA
AMINO ACID SEQUENCE: 20-11-13
TRAIT: HAIRLESS

GENE B
DNA:       AAA   TTT
mRNA: UUU AAA
tRNA:  AAA UUU 
AMINO ACID SEQUENCE: 9-8
TRAIT: LONG TAIL

GENE C
DNA:      CCT  GCG  GCG
mRNA: GGA CGC CGC
tRNA:   CCU GCG GCG
AMINO ACID SEQUENCE: 11-3-3
TRAIT: GRAY SKIN

GENE D
DNA:      TCG   GCT
mRNA: AGC CGA
tRNA:   UCG GCU
AMINO ACID SEQUENCE: 16-2
TRAIT: FOUR LEGGED

GENE E
DNA:      AAA   TTG
mRNA: UUU AAC
tRNA:  AAA UUG 
AMINO ACID SEQUENCE: 9-4
TRAIT: LARGE EARS

GENE F
DNA:       TAG   TAG   TCT
mRNA: AUC AUC AGA
tRNA:   UAG UAG UCU
AMINO ACID SEQUENCE: 6-6-14
TRAIT: MALE

GENE G
DNA:      CCA   TCC   TTT   GGG
mRNA: GGU AGG AAA CCC
tRNA:   CCA UCC UUU GGG
AMINO ACID SEQUENCE: 12-7-8-1
TRAIT: IVORY TUSK

GENE H
DNA:      CCA   CAT   AAT
mRNA: GGU GUA UUA
tRNA:   CCA CAU AAU
AMINO ACID SEQUENCE: 12-19-18
TRAIT: ELONGATED NOSE
PART 2.
DRAWING: DRAW THE ORGANISM/ PRESENT AN IMAGE OF THE ORGANISM
THAT WILL BE FORMED OUT OF THESE TRAITS (GENE A-GENE H).  

IDENTIFY THE ORGANISM: A MALE ELEPHANT


QUESTIONS FOR REFLECTION (one paragraph each only)

1. What is gene mutation?  Give examples of gene mutation.

Gene mutation are slight alterations of DNA or RNA nucleotide, genes or chromosomes that
may occur during replication or cell division. Random uncorrected errors may be beneficial or
harmful in relation to evolution. Some effects of gene mutation go unnoticed. A mutagen is an
agent of substance that can bring about a permanent alteration to the physical composition of a
DNA gene such that the genetic message is changed. Once the gene has been damaged or
changed the mRNA transcribed from that gene will now carry an altered message. The
polypeptide made by translating the altered mRNA will now contain a different sequence of
amino acids. The function of the protein made by folding this polypeptide will probably be
changed or lost. For example, the disorder sickle cell anemia is caused by a mutation in the gene
that instructs the building of a protein called hemoglobin. This causes the red blood cells to
become an abnormal, rigid, sickle shape. However, in African populations, having this mutation
also protects against malaria. Another example of gene mutation in flowers (rose), the enzyme
that is catalyzing the production of flower color pigment has been altered in such a way it no
longer catalyzes the production of the color (red) pigment. No production (red pigment) is
produced by the altered protein. In subtle or very obvious ways, the phenotype of the organism
carrying the mutation will be changed. In this case the flower, without the pigment is no longer
color red.

REFERENCES:

Dowd, D.M. (2021, April 21). Gene Mutation: Definition, Cause, Types, Examples. Retrieved
from https://sciencing.com/gene-mutation-definition-causes-types-examples-13718432.html

(n.d.). Retrieved from https://www.brooklyn.cuny.edu/bc/ahp/BioInfo/MUT/Mut.Definition.html

What is mutation? (202, May 5). Retrieved from https://www.yourgenome.org/facts/what-is-a-


mutation

2. What is eugenics?

Eugenics is the practice or advocacy of improving the human species by selectively mating
people with specific desirable heredity traits. It aims to reduce human suffering by “breeding out”
disease, disabilities, and so-called undesirable characteristics from the human population.
Eugenics was coined in 1883 by British explorer and natural scientist Francis Galton, who,
influenced by Charles Darwin’s theory of natural selection, advocated a system that would allow
“the more suitable races or strains of blood a better chance of prevailing speedily over the less
suitable.

REFERENCES:

History.com Editors. (2017, November 15). Eugenics. Retrieved from


https://www.history.com/topics/germany/eugenics

Wilson, P. (2021, June 4). Eugenics. Retrieved from


https://www.britannica.com/science/eugenics-genetics

3. What are the ethical concerns regarding gene therapy?


Gene therapy involves altering the genes inside the body’s cells in an effort to treat or stop
disease. Genes contain DNA - the code that controls much of the body’s form and function, from
making you grow taller to regulate the body system. Genes that don’t work properly can cause
disease. Gene therapy replaces a faulty gene or adds a new gene in an attempt to cure disease or
improve the body’s ability to fight disease. Gene therapy holds promise for treating a wide range
of diseases, such as cancer, cystic fibrosis, heart disease, diabetes, hemophilia and AIDS. Ethical
issues in genetic therapy involve the use of genetic science for human good and the avoidance of
preventable harms. Immediate issues are the control and confidentiality of the results of genetic
testing, possible discrimination against those found to have genetic diseases, and the just
allocation of beneficial genetic therapies. Less practical, but possibly more significant, dilemmas
involve the use of genetic science in ways that go beyond prevention and cure of disease. Such
use as trait enhancement and “Neo-eugenics” raise troubling ethical concerns. Furthermore, gene
therapy has some potential risks. A gene can’t easily be inserted directly into a cell. Rather, it
usually has to be delivered using a carrier, called vector. This technique presents the following
risks: unwanted immune system reaction, targeting the wrong cells, infection caused by the virus,
and possibility of causing a tumor.

REFERENCES:

Gene therapy. (2017, December 29). Retrieved from https://www.mayoclinic.org/tests-


procedures/gene-therapy/about/pac-20384619

Ethical issues in genetic therapy. (n.d). Retrieved from


https://www.sciencedirect.com/science/article/abs/pii/S0884217515331439

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