FRONT LINE COVID-19 CRITICAL CARE ALLIANCE

PREVENTION & TREATMENT PROTOCOLS FOR COVID-19

Behavioral Prevention

PREVENTION & EARLY OUTPATIENT

TREATMENT PROTOCOL FOR COVID-19 Page 1/2

PREVENTION PROTOCOL
lvermectin 1 Prevention for high risk individuals
0.2 mg/kg per dose (take with or after meals) — one dose
today, repeat after 48 hours, then one dose weekly*
Post COVID-19 exposure prevention2  WEAR MASKS
0.2 mg/kg per dose (take with or after meals)  — one dose Must wear cloth, surgical, or
today, repeat after 48 hours*
N95 mask (without valve) in
Vitamin D3 1,000–3,000 IU/day
all indoor spaces with non-­
Vitamin C 500–1,000 mg twice a day
household persons.
Quercetin 250 mg/day
Zinc 30–40 mg/day Must wear a N95 mask (with­

Melatonin 6 mg before bedtime (causes drowsiness) out valve) during prolonged
exposure to non-household
persons in any confined,
EARLY OUTPATIENT PROTOCOL 3
poorly ventilated area.
lvermectin1 
0.2–0.4 mg/kg per dose (take with or after meals) — one
dose daily, take for 5 days or until recovered*
 se upper dose range if:  1) in regions with more aggressive variants;
U
2) treatment started on or after day 5 of symptoms or in pulmonary
phase; or 3) multiple comorbidities/risk factors.
Fluvoxamine4 50 mg twice daily for 10–14 days
Add to ivermectin if: 1) minimal response after 2 days of ivermectin;
2) in regions with more aggressive variants; 3) treatment started on
or after day 5 of symptoms or in pulmonary phase; or 4) numerous
comorbidities/risk factors. Avoid if patient is already on an SSRI.
Nasopharyngeal Steamed essential oil inhalation 3 times a day (e.g. VapoRub)
Sanitation  and/or chlorhexidine/benzydamine mouthwash gargles and KEEP DISTANCE
Betadine nasal spray 2–3 times a day
Until the end of the Covid-19
Vitamin D3 4,000 IU/day
crisis, we recommend keep­-
Vitamin C 500–1,000 mg twice a day
ing a minimum dis­tance of
Quercetin 250 mg twice a day approx. 2 m / 6 feet in public
Zinc 100 mg/day from people who are not
Melatonin 10 mg before bedtime (causes drowsiness) from your own household.
Aspirin 325 mg/day (unless contraindicated)
Pulse Oximeter 
Monitoring of oxygen saturation is recommended
(for instructions please see page 2 of this file)

For optional medicines and an overview of the developments in prevention and

treatment of COVID-19, please visit www.flccc.net/optional-medicines.

* The dosing may be updated as further scientific studies emerge.

1
T
 he safety of ivermectin in pregnancy has not been established. A discussion of benefits vs. risks
with your provider is required prior to use, particularly in the 1st trimester.
2

To use if a household member is COVID-19 positive, or you have prolonged exposure to a COVID-19
positive patient without wearing a mask WASH HANDS
3

For late phase — hospitalized patients — see the FLCCC’s MATH+ Hospital Treat­ment Protocol for
COVID-19 on www.flccc.net We recommend, after a stay
4
Some individuals who are prescribed fluvoxamine experience acute anxiety which needs to be care- during and after outings
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fully monitored for and treated by the prescribing clinician to prevent rare escalation to suicidal or
violent behavior. from home (shopping, sub­­
way etc.), a thorough hand

Please regard our disclaimer and further information on page 2 of this document. cleaning (20–30 sec. with
soap), or also to use a hand
flccc.net © 2020–2021 FLCCC Alliance · I-MASK+ Protocol · Version 11 · June 30, 2021 disinfectant in between.
 FRONT LINE COVID-19 CRITICAL CARE ALLIANCE
PREVENTION & TREATMENT PROTOCOLS FOR COVID-19

PREVENTION & EARLY OUTPATIENT

TREATMENT PROTOCOL FOR COVID-19
Page 2/2

IVERMECTIN
Summary of the Clinical Trials Body weight conversion (kg/lb) for ivermectin
Evidence for Ivermectin in COVID-19 dose in prevention and treatment of COVID-19
Ivermectin, an anti-parasitic medicine whose
Body weight Dose
discovery won the Nobel Prize in 2015, has
Conversion (1 kg ≈ 2.2 lbs) 0.2 mg/kg ≈ 0.09 mg/lb
proven, highly potent, anti-viral and anti-­
(doses calculated per (Each tablet = 3 mg; doses rounded
inflammatory properties in laboratory studies. upper end of weight range) to nearest half tablet above)
In the past 4 months, numerous, con-
70–90 lb 32–40 kg 8 mg (3 tablets = 9 mg)
trolled clini­­cal trials from multiple centers and
countries worldwide are reporting consistent, 91–110 lb 41–50 kg 10 mg (3.5 tablets)

large improvements in COVID-19 patient 111–130 lb 51–59 kg 12 mg (4 tablets)

outcomes when treated with ivermectin. 131–150 lb 60–68 kg 13.5 mg (4.5 tablets)

151–170 lb 69–77 kg 15 mg (5 tablets)

Our comprehensive scientific review of these
referenced trials on ivermectin can be found on 171–190 lb 78–86 kg 16 mg (5.5 tablets)

191–210 lb 87–95 kg 18 mg (6 tablets)

www.flccc.net/flccc-ivermectin-in-the-
prophylaxis-and-treatment-of-covid-19/ 211–230 lb 96–104 kg 20 mg (7 tablets = 21 mg)

231–250 lb 105–113 kg 22 mg (7.5 tablets=22.5 mg)

For a quick overview, a One-page Summary
251–270 lb 114–122 kg 24 mg (8 tablets)
of our review on ivermectin can be found on
271–290 lb 123–131 kg 26 mg (9 tablets = 27 mg)
www.flccc.net/one-page-summary-of-the-clini-
291–310 lb 132–140 kg 28 mg (9.5 tablets=28.5 mg)
cal-trials-evidence-for-ivermectin-in-covid-19/

Pulse Oximeter (usage instructions)

In symptomatic patients, monitoring with home pulse oximetry – Use the index or middle finger; avoid the toes or ear lobe
is recommended (due to asymptomatic hypoxia). The limitations – Only accept values associated with a strong pulse signal
of home pulse oximeters should be recognized, and validated de- – Observe readings for 30–60 seconds to identify the most
vices are preferred. Multiple readings should be taken over the common value
course of the day, and a downward trend should be regarded – Remove nail polish from the finger on which measurements
as ominous. Baseline or ambulatory desaturation < 94% should are made
prompt hospital admission. The following guidance is suggested: – Warm cold extremities prior to measurement

DISCLAIMER
The I-Mask+ Prevention & Early Outpatient Treatment Protocol for COVID-19 and the MATH+ Hospital Treat­ment Protocol for
COVID-19 are solely for educational purposes regarding potentially beneficial therapies for COVID-19. Never disregard professional
medical advice because of something you have read on our website and releases. It is not intended to be a substitute for profes-
sional medical advice, diagnosis, or treatment in regards to any patient. Treatment for an individual patient should rely on the
judgement of your physician or other qualified health provider. Always seek their advice with any questions you may have regard-
ing your health or medical condition.

A summary of the published data supporting the rationale for Ivermectin use in our I-MASK+ protocol can be downloaded
from www.flccc.net/flccc-ivermectin-summary
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!
Please check our homepage www.flccc.net regularly for updates of our COVID-19 Protocols! – New medications may be
added and/or dose changes to existing medications may be made as further scientific studies emerge!

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