Pp-Ii MCQS With Ans
Pp-Ii MCQS With Ans
Pp-Ii MCQS With Ans
(a) Suspension
(b) Colloid
(c) Emulsion
a) Tyndall effect
Scattering
(Less than 1 nm
6) Lyophobic
(Associated
(a) Coacervation
(b) Peptization
(c) Flocculation
(d) Coagulation
7. The phenomenon which involves separation of macromolecular solutions into two liquid
layers is caled as ..
(b) Coagulation
(c) Flocculation
(d) Coacervation
(a) Solubility
(b) Turbidity
(c)Density
9. is the movement of dispersion medium below the impact of an electric field in the
condition when the movement of colloidal paticles is prohibited with the help of an
appropriate membrane.
(a)Electrosmosis
(b) Osmosis
CPhotosmosis
10. is the method of combining negatively and positively charged hydrophilic colloids.
(a) Coacervation
(6) Peptization
(c) Flocculation
(d) Coagulation
1. A shear stress-shear rate relationship is generally explained in the form of curve ie. or
(a) Rheogram
2. The cgs physical unit for kinematic viscosity is the stokes (St).
() Newton
(6) Increases
(a) Decreases
C)Sustainly increases
4. The cunve for a pseudo plastic material rheogram
(a) Increases
(d) Decreases
()shear-thinning systems
(a) Duration through which sample is exposed to any one shear rate.
8. .............. is the isothermal and moderately slow recovery on standing of material of which
(a) Thermochemistry
(b) Viscosity
(c) Entiotropy
(d) Thixotropy
9. iS the alteration in the shape and the size cf a body owing to applied external torcesS
(a) Deformation
(b) Formation
(c)Conjugation
10. is the deformation in term of relative displacement of the particles comprising the
body.
(a) Strain
(b) Stress
(c)State
(d) Shear
(c)Surface volume
3. The equal distribution of all the ions in solution retain by..
(a)-05 to +05 mV
(C)-20 to +20 mV
5. determines the movement of charged particles via a liquid under the impact of an
(b) Electrosmosis
(a) Electrophoresis
() Surface charge
(b) Electrophoresis
(a) Electrosmosis
(b) Quickly
(a) Slowly
(d) None of the above
(C)More quickly
(b) Deflocculated
(a) Flocculated
(a) Thickening
(D). Cracking
(a) Creaming
(d) State
()Phase inversion
The physical, chemical, and pharmacologic properties of a drug are directly affected by
(a) Size
(b) Microscopy
(a) Micromeritics
(c) Rheology
(Millimeter (mm)
b) 10° m
(a) 10 m
(d) 10 m
()10 m
(b) Suspensions
(a) Emulsions
(b) Diameter
(a) Area
(d) Volume
(Radius
7. is the diameter of a sphere having the same observed area as the paticle when
viewed normal to its most stable plane.
C)Particle mean
(b) Vacuum
(d) Weighing
()Filtration
10. The ratio of the void volume to the bulk volume of the packing is called as the ..
(d) Porosity
(c)Followability
1. .......... iS the time necessary for the concentration of the reactant to decrease to 90% of its
original concentration.
(a) Delivering evidences of the change in quality of the drug product with time.
(a) Dependent
( Independent
4. In a second-order reaction, the sum of the exponents in the rate law is equal to .
One
(a) Zero
(6)
Three
(d)
() Two
5. technique is utilized only during determination of order of reaction, when the rate
a)The concentration
reaction.
(b) Decrease
(a) Increases
(b) Decreases
(a) Increases
(c)Remains constant
10. The drug molecule is degradate by exposure of light it affects substantial degradation of
A. Dilatants
B. Newtonian
C. Plastie
D. Pscudoplastie
A. Balance
B. Electrode
C. Hydronmeter
D. Pipette
D. none of above
reaction.
A. Zero
First
B.
C. Second
D. Pseudo first
5) Awetting agent is included in the formulation of a suspension, particularly
A. Are hydrophobic
A. Lyophilic colloids
B. Lyophobic colloids
C. Association colloids
D. lydrophilie colloids
7) Which one of the follow ing physical property iw NOT a rheologleal property?
B. Spreadability
C. Surface tension
D. Viscosity
8) When the angle of repose in between 25-30" i” willindicate that the powder
A. Exeellent
B. Good
C. Passable
D. Poor
kinetics.
Zero
First
Second
Pseudo first
7) Which one of the follow ing physieal property is NOT a rheologienl property?
B. Spreadability
C. Surface tension
D. Viscosity
8) When the angle of repose in between 25-30" it will indieat” that the powder
A. Exeellent
B. Good
C. Passable
D. Poor
-0r'd’r
Kineties.
A. Zero
First
C. Second
D. Pseudo first
Owhw
w/olo
C. w/oluw
D. w/o/w
A. Lyophilic colloids
B. Lyophobie colloids
C. Association colloids
D. Micelle
B. Extrusion
C. Rotating sphere
D. Rotating spindle
14) In Coulter-counter, as the particles travel through the orifice, the event that
occurs is.
D. Sedimentation increases
15) The HLB range of an emulsifier used in the preparation of W/O emulsion is-
A. 3 to 6
B. 7 to 12
C. 13 to 15
D. more than 15
16) The half life of substance in first order kinetics expressed by--
A. 0.301/K
B. 0.693/K
C. 0.105/K
D. Ki/0.693
A. Absolute viscosity
B. Dynamic viscosity
C. Kinematic viscosity
D. Viscosity coefficient
A. Equal to one
D.zero
19) In case of suspensions, all statements below are true EXCEPT that---
C. It is an injectable preparation
D. It is an oral preparation
Solid
B. Emulsion
C. Suspension
Solution
1.The Polyphusie system wheve nt least one dimensdon of the dispersed system in
Suspension
Emulsion
Micromerities
Colloidal dispersion
Hydrophilie colloids
Coacervation
Peptization
Flocculation
Coagulation
Higher, Lower
Lower, ligher
Lower, Lower
Both A & B
Dilatants
Newtonian
Plastic
Pscudoplastic
Strong beam of light paussed through colloidul particle solution becomes visible as
Seutterig elfect
Electric effeet
Tyndall Efect
Dilution Test
Equal to one
Zero
Transparent
Bulky
Cohesive
Adhesive
In Coulter-counter, as the particles travel through the orifice, the event that occurs
Is.
Sedimentation increases
When the angle of repose in between 25-30° it willI indicate that the powder
Excellent
Good
Passable
Poor
Particle Size
Surface area
True density
Sedimentation rate
0.1
0.01
0.001
Extrusion
Rotating sphere
Rotating spindle
15.The Distance between two tangents on opposite sides of the particle parallel to
Martin Diameter
Feret’s diameter
Stoke’s Diameter
Molecules
Electrons
Fractional value
All of these
The Half life (tua) of substance in first order kinetics is expressed by..
0.301/K1
0.693/K1
0.105/K1
K1/0.693
18. The unit of specific reaction rate constant for second order reaction is..
Second
Zero-order kineties with a rate constant of 2 mg mL month’. If the initial concentration is 100 mg mL’,
what is the shelf life?
3 months
4 months
5 months
6 months
Limit is…
Heckel Plot
Hookes Law
Poisson’s ratio
Stress
B. Emulsion base
A. Oleaginous
D. Absorption base
B. Lotions
A. Suspensions
D. Creams
C. Emulsions
B. Acacia
A. Starch
C. Tragacanth
D. Methyl cellulose
A. Anderson pipette
B. Microscope
C. Coulter counter
D. Burette
A. Michaelis-Menten equation
B. Noyes-Whitney equation
C. Handerson-Hasselbalch equation
Thixotropic flow
Dilatant flow
Pseudoplastic flow
Newtonian flow
B. Polyviny! pyrrolidone
A. Sodum alginate
C. Ethyl cellulose
A. Hydrophilic groups
B. Lipophillic groups
C. Both A and B
Which of the following can be used to improve the flow rate of granules during tableting:
A. Antiadherant
B. Lubricant
C. Adhesive
D. Glidant
B. Bulk density
A. Young'’ modulus
C. Swelling ability
D. Carr’s index
A. Binder
D. Both B and C
B. Negative
C. Positive
A. Tartarates
B. Sorbitan
C. Lactylates
D. Lecithin
B. 7 to 9
A. 4 to 8
D. Zero to 3
C. 17 to 20
A. Cascade impactor
D. Beth A and B
C. Gas chromatography
B. Ointment
A Capsules
D. Solutions
C. Suspensions
A. 2k+1
D.1/k
C.k
Suspensions
Tincture
Elixir
Emulsion
B. Suspending agents
A. Wetting agents
D. Anti-foaming agents
C. Emulsifying agents
Multilple questions.
B. Rotational viscometer
A. Ultrasonifier
C. Accela cota
D. Chilsonator
B. Non-Newtonian
A. Newtonian
D. Dilatant
C. Pseudoplastic
B. Density of liquid
A. Weight of liquid
C.Unit time
A. Newtonian flow
B. Pseudoplastic
C. Dilatant
D. Plastic flow
surface tension
A. X-ray diffraction
D. Sedimentation method
B. Interfacial tension
A. Surface tension
C. Both (a) and (b)_
A. Increase
B. Decrease
A. 1 nm to 1 um
B. 1 nm to 0.5 um
C.1 nm to 100 nm
A. Fusion temperature
B. Collapse temperature
D. HLB temperature
C. Transition temperature
B. Bulkiness
A. Porosity
C. Both (a) and (b)
B. Fluidity
A. Mobility
C. Yield value
D. Yield stress
C. Porosity
xv) When the inorganic particles such as gold and silver, are
A. Lyophobic dispersion
B. Lyophilic dispersion
C. Amphiphilic dispersion
A. Square
B. Rectangular
C.Spherical
D. Oblong
particles is called
B. Analytical Balance
A. Hydrometer
D. Coulter counter
C. Andreason pipette
C. F of resistance
B.Excelient
A. Poor
D. Good
C. Very poor
B. Lecithin
A. SLS
C. Tween 80
D. Benzalkonium chloride
S. Y. B. Pharm. Sem IV
CBCS Pattern
Physical Pharmacy II
Practice Questions & Answer Key
1. When one of the reactants is present in such great excess then its concentration may be
considered constant or nearly so, the reaction is said to be ________
(a) Zero order (b) Apparent zero order (c) First order (d) Second order
2. The particle size range of colloidal dispersion is _____
(a) 1 nm to 1 µm (b) 1 nm to 0.5 µm (c) 1 nm to 100 nm (d) Greater than 100 nm
3. Inorganic particles such as gold and silver dispersed in water form ___________
(a) Lyophilic (b) Lyophobic (c) Amphiphilic (d) they do not form colloids
4. Suspension follows _____ kinetics.
(a) Zero-order (b) Apparent zero-order (c) First order (d) Pseudo order
5. Influence of temperature on drug decomposition is expressed by
(a) Arrhenius equation (b) Rutherford’s equation (c) Langmuir’s isotherm (d) BET
equation
6. Permitted amount of drug degradation during its shelf life is
(a) 1% (b) 10% (c) 15% (d) 90%
7. Guidelines on stability testing are given by
(a) USP (b) Govt. of India (c) ICH (d) BPC
8. Accelerated stability studies help in predicting …………
(a) expiry date (b) solubility (c) order (d) molecularity
9. Specific reaction rate constant is a parameter of
(a) chemical reaction (b) suspension (c) Dissolution (d) Diffusion
10. Molecularity of reaction gets influenced by ………..
(a) time (b) pressure (c) temperature (d) it never changes
11. Molecularity of a reaction can never be ……………..
(a) 1 (b) 2 (c) 3 (d) 0
12. Dissolution rate can be determined by ……………
(a) Fick’s law (b) Arrhenius equation (c) Noyes Whitney equation (d) Henderson
Hasselbalch equation
13. Transport cell is used for measurement of ………………….
(a) dissolution rate (b) diffusion rate (c) order (d) molecularity
14. Molecular dispersions have size …………………
(a) less than 1nm (b) equal to 1 nm (c) more than 1nm (d) more than 2 nm
15. Molecular dispersions undergo ………….
(a) no diffusion (b) slow diffusion (c) rapid diffusion (d) sedimentation
16. Suspension is an example of …………
(a) colloid (b) coarse dispersion (c) true solution (d) semisolid
17. Dispersed phase and dispersion medium are components of …….
(a) liquids (b) dispersions (c) solids (d) semisolids
18. Glucose in water will be an example of ………….
(a) suspension (b) emulsion (c) colloids (d) true solution
19. Polymer solutions are examples of …………..
(a) suspension (b) emulsion (c) colloidal dispersion (d) true solution
20. Emulsions are having ……….. as one of their components.
(a) Diluents (b) Glidants (c) Coating material (d) emulsifying agents
21. Emulsions are destabilized when they are ………….
(a) heated (b) cooled (c) kept at room temperature (d) prepared
22. Emulsions are examples of ………….
(a) colloid (b) coarse dispersion (c) true solution (d) semisolid
23. Flocculation is a phenomenon seen in …………..
(a) suspensions (b) solutions (c) emulsions (d) semisolids
24. Full form of BCS is ……………..
(a) Biopharmaceutical Classification System
(b) Biological Classification System
(c) Bioinformatics Classical System
(d) Biopharmaceutics Classical System
25. Suspensions are ……………….
(a) molecular dispersions (b) true solutions (c) coarse dispersions (d) colloids
26. Shelf life determination of pharmaceutical dosage form uses the principles of …………..
(a) Arrhenius equation (b) Rutherford’s equation (c) Langmuir’s isotherm (d) BET
equation
27. For a chemical reaction to occur there is need of proper collision of reacting molecules
along with sufficient kinetic energy. It is stated by……………………..
(a) Electronic theory (b) Collision theory (c) Activated complex theory (d) BCS
28. Order of a chemical reaction can be estimated from the ……..
(a) molecularity (b) molecular formula (c) rate law (d) melting point
29. Emulsions are thermodynamically ………….
(a) stable (b) safe (c) unstable (d) unsafe
30. Effect of temperature on rate of a chemical reaction is explained by ………..
(a) (a) Electronic theory (b) Collision theory (c) Activated complex theory (d) Arrhenius
equation
31. In flocculation occurring in suspension, the particles in floccules are held by ______?
(a) Repulsive forces (b) Gravitational force (c) Vanderwaal forces (d) None of the above
32. Which of the following is an instability of emulsion?
(a) Breaking (b) mottling (c) uneven surface (d) picking
33. Coalescence is a phenomenon that is observed in …………….
(a) Suspensions (b) emulsions (c) suppositories (d) tablets
34. Surfactants play the role of ………………
(a) increasing viscosity (b) reducing surface tension (c) increasing kinetic energy (d)
increasing sedimentation
35. The purpose of an emulsifier is to ………
(a) decrease surface area in suspension (b) reduces interfacial tension between immiscible
phases (c) minimizes globule size (d) improves taste of medication
36. Ethylene diamine tetraacetic acid (EDTA) is a ………………………..type of ligand.
(a) Unidentate (b) bidentate (c) tetradentate (d) hexadentate
37. Ligands with multiple binding sites are called ………
(a) Unidentate (b) bidentate (c) tetradentate (d) polydentate
38. The ______ sphere is enclosed in brackets in formulas for complex species, and it
includes the central metal ion plus the coordinated groups.
(a) ligand (b) donor (c) oxidation (d) coordination
39. In coordination chemistry, the donor atom of a ligand is ……………
(a) a Lewis acid (b) the counter ion(c) the central metal atom. (d) the atom in the ligand
that shares an electron pair with the metal.
40. What is the driving force for Fick’s law?
(a) Concentration (b) concentration gradient (c) pressure (d) temperature
41. Particles settle down under the influence of gravity in ………………..
(a) True solutions (b) Colloids (c) Suspensions (d) Molecular dispersions
42. Lyophobic colloids are also called as ……………………
(a) Solvent loving (b) solvent hating (c) solvent neutral (d) solvent non reacting
43. Lyophilic colloids are also known as ……………………..
(a) Solvent loving (b) solvent hating (c) solvent neutral (d) solvent non reacting
44. Sand in water is an example of …………………
(a) Solution (b) suspension (c) emulsion (d) colloid
45. Sugar in water is an example of ………………..
(a) Solution (b) suspension (c) emulsion (d) colloid
46. Tyndal effect is exhibited by …………………..
(a)Solution (b) suspension (c) emulsion (d) colloid
47. Brownian movement is exhibited by …………………..
(a)Solution (b) suspension (c) emulsion (d) colloid
48. Phase inversion is exhibited by ………………………..
(a)Emulsions (b) suspension (c) solution (d) colloid
49. Dissolution rate studies are carried out by …………….. apparatus.
(a)Homogenizer (b) stability chamber (c) dissolution testing apparatus (d) Horizontal
transport cell
50. The reaction where the rate is independent of concentration of reactants is called as
…………order reaction.
(a) Zero (b) first (c) pseudo (d) second
S. Y. B. Pharm. Sem IV
CBCS Pattern
Physical Pharmacy II
Answer Key
Q1.b
Q2.b
Q3.b
Q4.b
Q5.a
Q6.b
Q7.c
Q8.a
Q9.a
Q10.d
Q11.d
Q12.c
Q13.b
Q14.a
Q15.c
Q16.b
Q17.b
Q18.d
Q19.c
Q20.d
Q21.a
Q22.b
Q23.a
Q24.a
Q25.c
Q26.a
Q27.b
Q28.c
Q29.c
Q30.d
Q31.c
Q32.a
Q33.b
Q34.b
Q35.b
Q36.d
Q37.d
Q38.d
Q39.d
Q40.b
Q41.c
Q42.b
Q43.a
Q44.b
Q45.a
Q46.d
Q47.d
Q48.a
Q49.c
Q50.a