Os 2
Os 2
Os 2
(Local Anesthesia)
Lec.: 1 Dr. Saif Saadedeen
Local anesthesia has been defined as “loss of sensation in a circumscribed area of the
body caused by inhibition of the conduction process in the peripheral nerves”.
An important feature of local anesthesia is that it produces this loss of sensation without
inducing loss of consciousness. In this one major area, local anesthesia differs
dramatically from general anesthesia.
Many methods are used to induce local anesthesia. However, only those methods or
substances that induce a transient and completely reversible state of anesthesia have
application in clinical practice.
Brief history:
Local anesthesia as it is known today began when a German chemist (Albert Niemann-
1860) successfully isolated the active principle of coca leaf, he named it cocaine. In 1898
professor Heinrich Braun introduced procaine as the first derivative of cocaine which is
known as the first synthetic local anesthetic drug. In 1940 the first modern local anesthetic
agent was introduced and known as Lidocaine (trade name Xylocaine). It relieves pain
during the dental surgeries and produces the desired anesthetic effect for several hours.
Terminology:
Pain: According to the World Health Organization (WHO) pain is defined as an
“unpleasant sensation that occurs from imminent tissue damage”. From a physiological
perspective, pain is a warning system. During dental treatment, patients will experience
pain as something unpleasant.
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The effect of local anesthetics on nerve fiber has been shown to be dependent on:
1- The duration of exposure of local anesthesia
2- Concentration
3- Volume of the solution
Relative analgesia: is a sedation technique in which the patient remains conscious but
mental relaxation is induced by inhalation of a mixture of nitrous oxide and oxygen.
Of paramount importance is systemic toxicity, because all injectable and most topical
local anesthetics are eventually absorbed from their site of administration into the
cardiovascular system.
Several of the more potent injectable local anesthetics (e.g., procaine, mepivacaine)
prove to be relatively ineffective when applied topically to mucous membranes. To be
effective as topical anesthetics, these drugs must be applied in concentrations that prove
to be locally irritating to tissues while increasing the risk of systemic toxicity.
Clinical duration of action does vary considerably among drugs and also among different
preparations of the same drug, as well as by the type of injection administered (e.g., nerve
block vs. supraperiosteal). The duration of anesthesia necessary to complete a procedure
is a major consideration in the selection of a local anesthetic.
A. Diagnostic:
Administration of LA can be a useful way of finding the source of patient’s pain. An
example of this is the pain of pulpitis which can be very difficult for both the patient and the
dentist to isolate because of its tendency to be referred to other parts of the mouth or face,
so LA can differentiate between maxillary and mandibular sources, and even between
individual upper teeth provided they are not immediately adjacent.
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Another example is a patient with myofacial pain who is convinced that an upper tooth is
causing the problem, LA may help this patient and the surgeon in this situation to eliminate
the tooth as the cause of pain and may thus avoid unnecessary treatment.
B. Therapeutic:
LA can constitute part of a treatment for painful conditions, for example, the use of block
technique to eliminate the pain of dry socket. Blocks of the inferior alveolar nerve, mental
nerve or infraorbital nerve can also be used for the treatment of trigeminal neuralgia when
pain breakthrough.
C. Preoperative:
The provision of pain-free operation is by far the most common use of LA providing an
effective and safe method for almost all outpatient dentoalveolar surgical procedures. It
can in conjunction with sedation techniques allows more difficult procedures to be carried
out without the additional risks of general anesthesia and this is particularly of value in
patients with significant cardiovascular or airway diseases.
1- Absolute contraindications:
A. History of allergy to local anesthetic agent
Local anesthetic agents belong to the same chemical group should not be used.
However, LA agents in the different chemical group can be used. For example, if the
patient gives a history of allergy to an amide local anesthetic agent, an ester LA agent
should be used.
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2- Relative contraindications:
A. Uncooperative patient.