Pharmaceutical Calculations-BLUE PACOP

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The document covers a wide range of pharmaceutical calculations including unit conversions, dosage calculations, dilution problems, and flow rate calculations.

Some examples of calculations covered include conversions between milligrams, micrograms, grams and units. It also includes dosage calculations for patients based on their weight, height or body surface area as well as dilution and flow rate calculations for intravenous infusions.

Common units used in pharmaceutical calculations include milligrams, grams, micrograms, fluid ounces, teaspoons, tablespoons, liters and milliliters. Percentage solutions and molarity are also used.

PHARMACEUTICAL CALCULATION – PACOP BLUE

1. 0.0003g equals how many milligrams?


A. 0.009 C. 0.3
B. 0.09 D. 9

2. 0.016mg equals how many mcg?


A. 2 C. 16
B. 4 D. 320

3. 0.03 mg equals how many grams?


A. 0.000003 C. 0.0009
B. 0.00003 D. 0.009

4. ½ pint equals how many fluidounces?


A. 1 C. 4
B. 2 ½D. 8

5. 4 oz equals how many pounds?


A. ¼ C. 24
B. 1 D. 48

6. 6 tsp equals how many tbsp?


A. ½ C. 3
B. 2 D. 4

7. The physician orders the anticonvulsant phenytoin in an oral suspension 0.1g p.o. The pharmacy sends up a
bottle labeled 125mg in 5mL. How many mL should the nurse administer?
A. 0.004mL C. 6.25mL
B. 4mL D. 0.0004mL

8. The physician orders 1000mg of Acetaminophen (Tylenol) p.o. The only available tablets are 0.5g each.
How many tablets are needed to administer this dose?
A. 2 tabs C. 10 tabs
B. ½ tabs D. 12 tabs

9. Nystatin Oral Suspension 600,000 U is ordered. The bottle is labeled 1mL = 100,000 U. How many mL of
this antifungal agent should be administered?
A. 0.16mL C. 60mL
B. 6mL D. 0.016mL

10. The physician orders 500mg I.M. of Cefazolin Sulfate. The pharmacy supplies a vial of powder with the ff.
instructions; “Add 2.5mL of sterile WFI. This will provide an approximate volume of 330mg/ mL” How
many mL of this antibiotic preparation should be administered?
A. 0.66mL C. 1.5mL
B. 1.65mL D. 2.6mL

11. If 5 grams of pure drug have been dissolved in a solution that now measures 250mL, what percent strength
has been made?
A. 2% C. 0.02%
B. 4% D. 20%

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PHARMACEUTICAL CALCULATION – PACOP BLUE

12. How many grams of sodium chloride are in 2000mL of 0.9% NSS?
A. 1.8 grams C. 1800 grams
B. 18 grams D. 180 grams

13. The pharmacist must prepare a dilute solution of an oral antiseptic, cetylpyridinium chloride, from full
strength cetylpyridinium. How many mL of this antiseptic are needed to make 120mL of the 25% solution?
A. 20.8 C. 30
B. 20 D. 3

14. The antihistamine Diphenhydramine (Benadryl) has been prescribed for a child weighing 36 lbs. the bottle
reads; 1mL = 5mg. How many mL should the pharmacist prepare if the order reads 1.25mg/ kg p.o.?
A. 5.76 C. 0.24
B. 4.1 D. 2.88

15. A child weighing 50 lbs must receive Methylphenidate (Ritalin) therapy. What would be the safe dose of this
CNS stimulant if the recommended optimum daily dose is 2mg/ kg p.o.
A. 45 mg C. 50 mg
B. 100 mg D. 22 mg

16. An I.V. bolus of atropine, 0.3mg/ m2, has been ordered for a child with a BSA of 0.46m 2. How many mg of
this anticholinergic should the nurse administer?
A. 2.65 mg C. 1.5 mg
B. 0.14 mg D. 0.08 mg

17. The physician orders an infusion of 750mL of dextrose 5% in ½ in NSS over 8 hours. What is the
appropriate flow rate for this hypertonic solution when the tubing has a drop factor of 15 gtt =1mL?
A. 23 gtt/ min C. 67 gtt/ min
B. 42 gtt/ min D. 230 gtt/ min

18. The physician orders 500mL of D5W with 1 gram of lidocaine. The drop factor is 15gtt = 1mL. Which of the
flow rate is necessary if the patient is to receive 2mg/ min?
A. 2 gtt/ min C. 25 gtt/ min
B. 15 gtt/ min D. 70 gtt/ min

19. An infusion of isotonic NSS has been ordered for a 50-yr old patient who may need to undergo surgery. IF
500mL are ordered at a keep-vein-open (KVO) rate of 10 gtt/ min and the drop factor is 15gtt = 1mL, how
many hours will the infusion last?
A. 6 hours C. 12 ½ hours
B. 10 hours D. 15 hours

(# 20-21) SITUATION: A 50 kg patient is receiving an infusion of 250mL of D 5W with 100 mg of NTG at a


rate of 12mL/ hr;

20. How many mcg/kg/min of this coronary vasodilator is the patient receiving?
A. 12 mcg/kg/min C. 1 mcg/kg/min
B. 1.6 mcg/kg/min D. 100 mcg/kg/min

21. How many mg/kg/min is the patient receiving?

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PHARMACEUTICAL CALCULATION – PACOP BLUE
A. 0.0004 mg/kg/min C. 0.0016 mg/kg/min
B. 0.008 mg/kg/min D. 0.125 mg/kg/min

22. How many grams of boric acid powder, an antiseptic, are needed to prepare 200mL of a 2% solution?
A. 0.004 g C. 40 g
B. 10 g D. 0.1 g

23. A pediatrician performs a physical assessment of an infant during a well-body check-up. The infant
measures 62.5 cm. How many inches does this equal?
A. 158C. 23
B. 24.6 D. 15.8

24. A vial labeled 2.5% contains 50mL of a drug. What is the proportionate strength of the solution?
A. 1:4000 C. 1:0.025
B. 1:40 D. 1:2.5

25. 98.6 ⁰F equals how many degrees celcius?


A. 36.7 C. 38.6
B. 37 D. ?

26. The nurse’s note indicates that a patient is to receive 22 mg of a Topical Ointment applied daily. The
pharmacy sends up a tube of ointment labeled 2.54cm = 15mg. How many inches of ointment should the
nurse apply for each dose?
A. ½” C. 1 ½”
B. 1” D. 3”

27. A patient is to receive 375 mg of Ascorbic Acid (Vit. C) t.i.d. scored tablets of 250 mg each are available.
How many tablets should the pharmacist give for each dose?
A. ½ tab C. 2 tabs
B. 1 ½ tab D. 2 ½ tabs

28. Amoxicillin 0.5g is prescribed q 8 hrs. Amoxicillin Oral Suspension is labeled 250 mg/tsp. Give ______ mL:
A. 10mL C. 2.5mL
B. ? D. ?

29. What is the difference, in percent, between a 1:4 solution and a 10% solution?
A. 9.75% C. 10%
B. 15% D. no difference at all

30. Convert 40 ⁰C to ⁰F.


A. 40 C. -40
B. 144 D. 104

31. To prepare 400mL of a 2% sodium bicarbonate solution from a pure drug, you will need _____ gram of
solute.
A. 80 g C. 8 g
B. ? D. ?

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PHARMACEUTICAL CALCULATION – PACOP BLUE
32. To make 1.5 L of a 5% solution from a 25% solution, you would need _____ mL of solute. Add _____ mL of
water to make 1.5 liter.
A. 300 mL & 1200 mL C. 1200 mL & 300 mL
B. 1500 mL & 1200 mL D. 1000 mL & 300 mL

33. The physician prescribed an elixir for a 4-yr old who weighs about 30 pounds. The normal adult dose is 325
mg q 4 to 6 hrs. The elixir is available as 325mg/ 5mL. How many mL should the child receive? (use Clark’s
Rule: pediatric dose)
A. 1 mL C. 13 mL
B. 65 mL D. 15 mL

34. Dr. Alvin prescribed Milk of Magnesia for an 8-yr old patient. The normal adult dose is 30mL. Calculate the
pediatric dose. (use Young’s Rule)
A. 12 mL C. 20 mL
B. 1.6 mL D. 1.5 mL

35. The physician prescribed an elixir for a 15-month old. The normal adult dose is 325 mg q 4 to 6 hrs. The
elixir is available as 325 mg/ 5mL. How many mL should the child receive? (use Fried’s Rule: pediatric dose)
A. 40.6 mL C. 0.5 mL
B. 0.1 mL D. 32.5 mL

36. Find the BSA of an adult who weighs 55 kg and measures 157.5 cm (use the BSA equation)
A. 1.55 m2 C. 1.80 m2
2
B. 1.70 m D. 1.50 m2

37. Calculate the BMI of a person 4ft. 11 in. in height and weighing 98 lb. (Interpret the result: underweight=
under 18.5; normal= 18.5-24.9; overweight= 25-29.9; obese= 30 and over)
A. 18 C. 19
B. 19.8 D. 20

38. Calculate the Body Mass Index (BMI) for a person weighing 6 ft. 6 inches in height and weighing 240 lb.
A. 28 C. 29
B. 26 D. 25

39. How many proof gallons is represented by 54 wine gallon of alcoholic beverage with a percentage strength
of 50?
A. 54 C. 108
B. 27 D. 92

40. How many proof gallons is represented by 54 wine gallons of alcoholic beverage with a proof strength of 50?
A. 54 C. 108
B. 27 D. 92

41. A physician places a patient on a daily dose of 48 units of U-80 insulin. How many mL should the patient
inject each day?
A. 1.6mL C. 0.38mL
B. 0.60mL D. 0.48mL

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PHARMACEUTICAL CALCULATION – PACOP BLUE
42. How many mL of a 1:50 stock solution of ephedrine sulfate would be needed to prepare 30mL of the
following prescription?
Rx Ephedrine 0.25%
Normal saline qs 10mL

A. 3.75mL C. 2.4mL
B. 240mL D. 375mL

43. Strong Iodine Solution USP contains 5% w/v iodine. How many mg of iodine are consumed daily if the usual
dose is 0.3mL t.i.d?
A. 15 C. 5
B. 45 D. 0.2

44. A hospital pharmacy requests two pounds of 2% ammoniated mercury ointment. How many grams of 5%
ammoniated mercury ointment would be diluted with white petrolatum to prepare this order?
A. 18.2 C. 45.4
B. 27.5 D. 363

45. The physician prescribes Gemfibrozil 600 mg for Mr. Yin Yang. You have received a unit dose labeled
Gemfibrozil 0.6 gram from the pharmacy. What action should you take?
A. give the unit dose as sent from the pharmacy C. call the pharmacy to report a mistake in the dose
B. withhold the dose as sent from the pharmacy D. return the medication to the pharmacy

46. You have asked to administer Timolol 0.25% 1 gtt, bid, o.u to a patient with glaucoma. You placed one drop
in :
A. both eyes C. right eye
B. left eye D. both ears

47. You are transcribing the ff. prescription order to the medication sheet: Zantac 150 mg p.o. bid. What does
the order mean?
A. Administer Zantac 150 mg by mouth every other day.
B. Administer Zantac 150 mg by mouth twice a day.
C. Administer Zantac 75 mg twice a day, for a total of 150 mg in 25-hr period.
D. None of the above.

48. You have discovered that your junior pharmacist send instead of digitoxin. To prevent the error,
you should;
A. Give the drug after checking the “Five Rights”
B. Calculate a corrected dose of digoxin and dispense the drug, preparation are the same but only
have different strengths
C. Verify the correct dose with another pharmacist before giving the drug
D. Recall the dispensed digoxin and give the correct drug

49. While administering medications, you notice the medication ordered is digoxin 2.5 mg, and you find 0.5 mg
scored tablets available. You know the safe dosage range is 0.5 mg to 1.25 mg. Which of the following
action should you take?
A. give ½ tab C. give 5 tabs
B. give 1 tab D. call the physician and verify the dosage

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PHARMACEUTICAL CALCULATION – PACOP BLUE
50. When instructing Mr. Constantino, a patient who is prescribed Timolol eye gel, 0.5% q.d., you advise him to
instill ¼ inch of the gel :
A. after breakfast C. at bedtime
B. upon waking in the morning D. in the afternoon

51. A prescription calls for a dose of 3 tsp of a medicine to be administered q.i.d., 15 minutes before meals and
at bedtime. How many days will a 350mL bottle of the medicine last?
A. it will last for 6 days C. it will last for 5 days
B. it will last for 6 days, but there is not enough D. it will last for 5 days, but there is not enough
for 7 days for 6 days
52. A perfume oil has a specific gravity of 0.960 and costs Php 776.25 per kg. How much would 5 fluidounces
cost?
A. 111.15 C. 110.18
B. 109.15 D. 180

53. In what proportion should 10% and 2% coal tar ointment be mixed to prepare a 5% ointment?
A. 3:5 C. 2:3
B. 2:5 D. 3:7

54. Zinc sulfate is a 2-ion electrolyte, dissociating 40% in a certain concentration. What is its dissociation (i)
factor?
A. 4 C. 1.4
B. 6 D. 100

55. How many mL of 36% (w/w) HCL with a sp.gr of 1.18 are required to prepare 5 gal of 10% (w/v) HCL?
A. 0.0037mL C. 4,545mL
B. 0.00037mL D. 4,455mL

56. What is the proof strength of a 50% v/v solution of alcohol?


A. 100 proof C. 50 proof
B. 25 proof D. 150 proof

57. Two pints to a quart is equivalent to:


A. 4 C. 1
B. 8 D. 3

58. 11.35-1.19+0.638-2.5103= _______:


A. 8.3327 C. 8.8277
B. 8.2877 D. 8.327

59. The dispensing direction to the pharmacist:


A. inscription C. superscription
B. subscription D. transcription

60. If mercury freezes at -40⁰F, what is its freezing point on the centigrade scale?
A. 40 C. 44.4
B. 4.4 D. -40

61. How many mL of 95% alcohol and 30% alcohol should be mixed to make 4000mL of 50% alcohol?

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PHARMACEUTICAL CALCULATION – PACOP BLUE
A. 1230 and 2770 C. 2500 and 1500
B. 2770 and 1235 D. 2000 each

62. A prescription call for 325 mg of aspirin. After weighing this amount the pharmacist decided to check by
weighing again. Now she finds that she has only 315 mg. What is the percentage error?
A. 3.11% C. 3.06%
B. 3.08% D. 3%

63. Five mL of Lithium Citrate Syrup contain the equivalent of 8 mEq of Li+. Calculate the equivalent, in mg of
Lithium Carbonate (Li2CO3 = MWt=74) in each 5mL dose of the syrup.
A. 592 mg C. 118.4 mg
B. 296 mg D. 0.1184 mg
64. Ammonium chloride (NH4Cl=MWt,=53.5) is to be used as urinary acidifier with a dose of 150 mEq. How
many 500 mg-tablet should be administered?
A. 16 C. 5
B. 8 D. ½

65. How many mL of a 2% (w/v) solution of NH4Cl (MWt.=53.5) should be administered intravenously to a
patient to provide 75 mEq?
A. 0.0803mL C. 100.3mL
B. 200.6mL D. 2.006mL

66. Prof. J.C. Cruz os to receive 4 mEq of sodium chloride per kg of BW. If show weighs 165 lbs., how many mL
of NSS should be administered? (NaCl = MWt. = 58.5)
A. 975mL C. 3900mL
B. 1950mL D. 2000mL

67. A pharmacist adds 20mL of a Calcium Chloride injection, labeled 4 mEq/mL to a 500mL bottle of D 5W
injection. What is the concentration of the calcium chloride expressed as mg/mL in the final admixture?
(CaCl2•H2O = MWt. = 147)
A. 294 mg/mL C. 11.31 mg/mL
B. 11.76 mg/mL D. 14.7 mg/mL

68. What is the sodium chloride (E) equivalent of tetrahydrozoline HCL?


Rx Tetrahydrozoline HCL 0.50 g
Sodium Chloride q.s.
Distilled water ad 50.0mL
Make an isotonic solution

A. 0.25 C. 0.027
B. 0.24 D. 0.26

69. How much NaCl should be used in compounding the prescription?


Rx Tetrahydrozoline HCL 0.50 g
Sodium Chloride q.s.
Distilled water ad 50.0mL
Make an isotonic solution

A. 0.45 g C. 0.045 g

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PHARMACEUTICAL CALCULATION – PACOP BLUE
B. 0.325 g D. 0.25 g

70. Dr. Julienn Cruz prescribed 25 mg of ascorbid acid to be given orally to baby Jiro twice a day. How many mL
of ascorbic acid drops containing 46 grains per 15mL container should be used to provide for this dose?
A. 0.25 mL C. 0.4 mL
B. 0.125 mL D. 0.06 mL

71. What would be the correct directions to the patient if the signa in the prescription is “gtt ii o.u. b.i.d.”:
A. Two drops in the left eye twice a day C. Two drops in the right eye twice a day
B. Two drops in both eyes twice a day D. Two drops in the affected other eye twice a day

72. The standard temperature for specific gravity determination based on USP requirement (except in alcohol)
is:
A. 20⁰C C. 4⁰C
B. 15.56⁰C D. 25⁰C

73. Concentration of sodium chloride solution which is said to be isotonic with body fluids.
A. 0.09% C. 0.9%
B. 9% D. 0.009%

74. A solution with a concentration of 1:400 is the same as:


A. 0.25% C. 0.0025%
B. 4% D. ½%

75. The pharmacist prepares a 200 mcg dose of the anti-hypertensive drug Clonidine (catapres). If each tablet
equals 0.1 mg, the pharmacist should give the patient:
A. ½ tablet C. 2 tablets
B. 2 ½ tablets D. 1 tablet

76. It is used frequently to denote the concentration of a drug or natural substance in a biologic fluid, as in the
blood:
A. gram% C. mcg%
B. kg% D. mg%

77. 2332 is equivalent to:


A. MCCCXXXII C. MCMCCXXXII
B. MMCCCXXXII D. MMCCXXXII

78. A 25-kg child is to receive a dose of isotonic sodium chloride equivalent to 2% of her BW. Calculate in kg,
the correct amount of isotonic sodium chloride to be administered to this patient.
A. 50 C. ½
B. 0.05 D. 5

79. Cimetidine is a drug that can produce side effects such as dizziness and a rash. The number of people who
experienced these side effects is about 1% of all those who take the drug. If 1500 people take cimetidine,
how many persons are expected to experience the side effect?
A. 150C. 100
B. 15 D. ½

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PHARMACEUTICAL CALCULATION – PACOP BLUE
80. A hospital pharmacist combined 2-fluidounces of a povidone-iodine cleaner, 7.5% w/v, with 4-fluidounces of
a povidone-iodine topical solution, 10% w/v. Calculate the resulting strength of the povidone-iodine mixture.
A. 0.11% C. 9.17%
B. 9% D. 11%

81. What is the sp. gr. of a mixture containing 1000mL of water, 500mL of glycerin having a sp. gr. of 1.25, and
1500mL of alcohol having a sp. gr. of 0.81? (assume no contraction occurs when the liquid are mixed)
A. 1.630 C. 1.056
B. 0.613 D. 0.95

82. A physician orders Aminophylline suppositories, gr viiss, STAT and non rep. How much drug should each
suppository contain?
A. 7 grams C. 7 ½ grains
B. 7 grains D. 7 ½ grams

83. A solution contains 10 mg% Mg+2 (At. Wt>=24). How many mEq are there in one liter?
A. 8.33 C. 0.83
B. 4.17 D. 83.33

84. The formula for an elixir calls for 4 gallons of 95% alcohol. Alcohol, 95% costs Php 877.50 per gallon and
the drawback is Php 310.50 per proof gallon. Calculate the net cost of the alcohol in the formula.
A. P 1,153.50 C. P 1,141
B. P 1,150.20 D. P 1,100

85. 0.25 mg equals how many mcg?


A. 0.025 C. 250
B. 25 D. 500

86. ½ quart equals how many fluidounces?


A. 16 C. 88
B. 32 D. 500

87. The physician orders the anticonvulsant phenytoin (dilantin) in an oral suspension 0.1 g p.o. The pharmacy
sends up a bottle labeled 125 mg in 5 mL. How many mL are needed?
A. 0.4 mL C. 15 mL
B. 4 mL D. 27 mL

88. Dra. J. Constantino has ordered Colchicine, an anti-gout medication, 1.2 mg p.o. daily on a prophylactic
basis. Available tablets are 600 mcg each. How many tablets should be given daily?
A. 2 tabs C. 1 tab
B. ½ tab D. 20 tabs

89. Ms. Yoon-Hee, an 18-yr old patient with hyperthyriodism is to receive 0.3 g p.o. of propylthiouracil daily.
Available tablets are 50 mg each. How many tablets are needed for each dose?
A. 2 C. 10
B. 6 D. 12

90. ORDER: Adrenalin 0.4 mg SC q. 3h p.r.n. for asthma


SUPPLY: 1 mL ampule of adrenalin 1:1000

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PHARMACEUTICAL CALCULATION – PACOP BLUE
GIVE: _____
A. 0.4 mL C. 375 mL
B. 4000 mL D. 200 mL

91. 1:500 concentraion is expressed as:


A. 0.2% C. 1 g in 500 mL
B. 5% D. either a or c

92. Mr. A.S. Cruz is to receive 60-U of isophane insulin suspension (NPH) s.c. daily. The vial is labeled 100-
U=1ML. How many mL of this pancreatic hormone must be administered?
A. 0.09 mL C. 0.6 mL
B. 0.2 mL D. 45 mL

93. Doctor’s Order reads: “Bricanyl 0.25 mg, SC b.i.d.” The ampule is labeled 1mg/ mL. How many mL should
be administered to the patient?
A. 0.25 mL C. ¼ mL
B. 0.25 mL D. either a or c

94. How many grams of glacial acetic acid (99.9% w/w) must be added to 1 gallon of purified water to prepare
an irrigation containing 0.25% w/v acetic acid?
A. 9.5 C. 946.25
B. 0.95 D. 95

95. If a pharmacist dissolves the contents of eight capsules, each containing 250 mg of clindamycin
hydrochloride, into a sufficient amount of lonex astringent to prepare 120mL of solution, what is the
percentage strength (w/v) of clindamycin HCL in the prescription?
A. 1.67% C. 2%
B. 16.64% D. 1.69%

96. A sample of white petrolatum contains 10 mg of tocopherol per kg as a preservative. Express the amount of
tocopherol as a ratio strength:
A. 1:1000 C. 1:100,000
B. 1:10,000 D. 1:1,000,000

97. A 36mL aliquot was obtained from a mixture of 98% unknown solution. If half of the sample is diluted to
100mL, what is its final concentration?
A. 34.3% C. 17.85%
B. 17.15% D. 17.5%

98. Calculate the sodium content, in terms of mEq, of 1g of ampicillin sodium (MWt=371).
A. 2.9 mEq C. 2.7 mEq
B. 5.39 mEq D. 8 mEq

99. Four equal amount of belladonna extract, containing 1.15%, 1.30%, 1.35% and 1.20% of alkaloids
respectively, were mixed. What was the percentage strength of the mixture?
A. 0.8% C. 1.5%
B. 1.25% D. 1.4%

100. 190 proof strength alcohol is equivalent to:

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PHARMACEUTICAL CALCULATION – PACOP BLUE
A. 95% C. 100%
B. 190% D. 380%

101. Fifty mL of 1:20 w/v solution of aluminum acetate contains how many mg of aluminum acetate?
A. 2.5 C. 0.4
B. 2,500 D. 400

102. 11.35 – 1.19 + 0.638 – 2.5103 = _______.


A. 8.3327 C. 8.8277
B. 8.3877 D. none of the above

103. One kilogram is equivalent to:


A. 1000 mg C. 1000 grams
B. 2.4 pound D. 15.432 grain

104. If one tbsp is prescribed as the dose, approximately how many doses will be contained in one pint of the
medicine?
A. 7095 C. 31
B. 0.03 D. 3

105. The pharmacist prepares to administer a dose of 6 tsp of Drug X. What is the equivalent dose in tbsp?
A. 1 C. 1 ½
B. 3 D. 2

106. In what proportion of 95% and 50% alcohol must be mixed to prepare 70% alcohol?
A. 5:4 C. 4:5
B. 2:2:5 D. 2:25

107. The amount of 190 proof required to make a liter of 70% alcohol is:
A. 1357 mL C. 73.68 mL
B. 736.84 mL D. 1.357 mL

108. Two solutions that have the same osmotic pressure:


A. isotonic C. hypertonic
B. isosmotic D. hypotonic

109. The average BSA of an adult:


A. 1.76 m2 C. 1.73 cm2
2
B. 150 m D. 1.73 m2

110. How many 3 teaspoonfuls are there in a tablespoonful?


A. 6 C. 9
B. 1 D. 12

111. How many teaspoonfuls are there in 3 tablespoonfuls?


A. 6 C. 9
B. 1 D. 12

112. Convert 5% to mg/mL:

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PHARMACEUTICAL CALCULATION – PACOP BLUE
A. 500C. 5
B. 50 D. 5000

113. Admixture with solutions or mixture of greater strength or by evaporation of the diluents:
A. saturated C. supersaturated
B. diluted D. concentrated

114. Procaine Hydrochloride (MWt =273) is a 2-ion electrolyte, dissociating 80% in a certain concentration.
Calculate its: Dissociation (i) factor
A. 1.8 C. 2.8
B. 1.0 D. 2.0
115. Procaine Hydrochloride (MWt =273) is a 2-ion electrolyte, dissociating 80% in a certain concentration.
Calculate its: Sodium Chloride equivalent (E)
A. 0.21 C. 0.20
B. 0.23 D. 0.24

116. How many grams of anhydrous dextrose (E value= 0.18) should be used in preparing 1 liter of a ½%
isotonic ephedrine sulfate (E value= 0.23) nasal spray?
A. 7.85 C. 1.09
B. 43.61 D. 40

117. A solution contains 156 mg of K+ ion per 100mL. How many milliosmoles are represented in a liter of the
solution?
A. 80 C. 40
B. 3.9 D. 2.56

118. Calculate the osmolar concentration, in terms of millimoles, represented by 1L of a 10% w/v solution of
anhydrous dextrose (MWt =180) in water.
A. 555.56 mOsmoles C. 55.56 mOsmoles
B. 5.56 mOsmoles D. 5 mOsmoles

119. Pertusis vaccine contains 4 protective units per 0.5mL. How many protective units would be contained in a
7.5mL multiple dose vial?
A. 6 units C. 600 units
B. 60 units D. 0.6 units

120. If 1 mg of heparin sodium is equivalent to 140 USP heparin units, how many mcg of heparin sodium
represent in 1 Unit?
A. 140 mcg C. 7.14 mcg
B. 140,000 mcg D. 0.14 mcg

121. VERSED injection contains 5 mg of midazolam per mL of injection. Calculate the ratio strength of
midazolam in the injection.
A. 1:20 C. 1:2000
B. 1:2 D. 1:200

122. What is the percentage strength w/w of a solution made by dissolving 62.5 g of potassium chloride in
187.5mL of water?
A. 25% C. 400%

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PHARMACEUTICAL CALCULATION – PACOP BLUE
B. 33% D. 300%

123. If 1 g of a drug is dissolved in 2.5mL of glycerin, sp. gr. 1.25, what is the percentage strength (w/w) of the
drug in the resultant solution?
A. 33.33 C. 200
B. 24.24 D. 412.5

124. If a topical cream contains 1.8% (w/w) of hydrocortisone, how many mg of hydrocortisone should be used
in preparing 15g of the cream?
A. 270 C. 27
B. 0.27 D. 0.027

125. How many 0.1 mg tablets will contain the same amount of drug as 50 tabs, each of which contains 0.025
mg of the identical drug?
A. 8 tabs C. ½ tabs
B. 10 tabs D. 12 ½ tabs

126. If 10 pints of a 5% solution are diluted to 40 pints, what is the percentage strength of the dilution?
A. 20% C. 200%
B. 1.25% D. 0.125%

127. Ms. Maria, a registered pharmacist, had 3 ounces of Hydromorphone HCL. She used the following: 1/8
ounce, ¼ oz, ½ ounces. How many ounces of Hydromorphone HCL were left?
A. 1.125 C. 11.25
B. 1 1/8 D. both a and b

128. AJ receives daily medication doses of 0.5 mg at breakfast, ½ mg and 250 mcg at lunch, and 0.75 mg at
dinner. How many grams does AJ consume each day?
A. 0.002 C. 0.02
B. 0.0002 D. 0.2

129. In preparing a certain ointment, Ms. M. Andal, a registered pharmacist used 28.35 grams of zinc oxide
instead of the 31.1 gram called for. Calculate the percentage of error on the basis of the desired quantity.
A. 91.16% C. 8.84%
B. 0.09% D. 88.4%

130. If 30mL represent 1/6 of the volume of a prescription, how many mL will represent ¼ of the volume?
A. 45 mL C. 37.5 mL
B. 40 mL D. 42 mL

131. Last November 13, 2008, Dra. Bautista delivered triplets at Delgado Memorial Hospital in Quezon City.
The babies weighed 2100g, 2kg and 6.622 lb. What was the sum weight of the triplets in kilograms?
A. 10.72 C. 18.67
B. 7.11 D. 7.67

132. A prescription cost the registered pharmacist Php 1,890 for a bottle of 100 tabs. What would be the cost
for 24 tabs?
A. 450 pesos C. 453.60 pesos
B. 45 pesos D. 400 pesos

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133. Ampuls of amyl nitrite inhalant each contain 0.3mL of amyl nitrite, having a sp. gr. of 0.87, how many g of
the drug would be used in preparing 4000 ampuls?
A. 137.9g C. 1044g
B. 1379.3g D. 11600g

134. The dose for a patient weighing 150 lbs is 1.5g. What would be the dose for a patient weighing 90 lbs?
A. 13.85 gr C. 0.9 g
B. 900 mg D. any of the choices

135. A rectal dose of sodium thiopental is 45 mg/kg of BW. How many mL of 10% solution should be used for a
person weighing 150 lb?
A. 31 C. 3.068
B. 0.31 D. 3.10

136. If 198 g of dextrose are dissolved in a liter of water, what is the percentage strength (w/w) of the solution?
A. 19.8% C. 60.50%
B. 16.53% D. 0.198%

137. Purified water contais NMT 10 ppm of total solids. Express this concentration as a percentage..
A. 0.01% C. 0.0001%
B. 0.01% D. 0.00001%

138. What is the ratio strength (w/v) of a solution made by dissolving five tablets, each containing 2.25 g of
NaCl, in enough water to make 1800mL?
A. 1:60 C. 1:160
B. 1:1600 D. 1:0.625

139. Lugol’s solution contains 5g of iodine per 100mL and its usual dose is 0.3mL t.i.d. How many mg of iodine
are represented in the daily dose?
A. 45 C. 4.5
B. 15 D. 0.05

140. A physician prescribed keflex, 250 mg q.i.d. x 10 days, how many mL of keflex suspension containing 250
mg per 5mL should be dispensed?
A. 200 mL C. 62.5 mL
B. 2 mL D. 6.25 mL

141. Rx
Sol. Ephedrine Sulfate ½%
30mL

Sig. For the nose

How many mg of ephedrine sulfate should be used in preparing the Rx?


A. 60 C. 15
B. 6 D. 150

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142. A dose of 10,000 mcg is prescribed for your patient. You have the medication with a dose strength of 4 mg
per 1mL. How much medication, in mL should you give to your patient?
A. 250 C. 2.5
B. 0.25 D. 0.025

143. If a sample of the drug herb ginseng is determined to contain 1:25 of pharmacologically active
ginsenosides, calculate the mg of the herb containing 10 mg of the active constituents.
A. 0.4 mg C. 4 mg
B. 0.04 mg D. 40 mg

144. If two patients, each weighing 100 lb, were given the drug amikacin sulfate, one at a regimen of 7.5 mg/kg
q 12 hrs and the other at 5mg/kg q 8 hrs. What is the difference in the total quantity of drug administered
over a 24 hour period?
A. 125 mg per day C. 250 mg per day
B. none D. 75 mg per day

145. A physician prescribed 5 mg of a drug per kg of BW once daily for a patient weighing 132 lb. How many
100 mg tablets of the drug are required for a dosage regimen of 2 weeks?
A. 42-100 mg tabs C. 14-100 mg tabs
B. 6-100 mg tabs D. 24-100 mg tabs

146. A child measures 42 in tall and weighs 50 lb, what is its BSA? (Use the BSA equation)
A. 0.82 m2 C. 1.22 m2
2
B. 0.52 m D. none of the above

147. If the dose of a drug is 5 mg for every m2, what would be the dose in mg for a patient with a BSA of
1.92m2?
A. 5.55 mg C. 4.80 mg
B. 9.6 mg D. 2 mg

148. How many mL of U-100 insulin should be used to obtain 40 units of insulin?
A. 2.5 mL C. 0.4 mL
B. 250 mL D. 25 mL

149. How many mL of water must be added to 250mL of a 25% w/v stock solution of sodium chloride to
prepare a 0.9% w/v NaCl solution?
A. 6,944 C. 6,494
B. 6,964.40 D. 6,694.4

150. How many of 95% v/v alcohol and 30% v/v alcohol should be mixed to make 4000mL of 50% v/v alcohol?
A. 2769mL of 95% alcohol and 1231mL of 30% alcohol
B. 1231mL of 95% alcohol and 2769mL of 30% alcohol
C. 2769mL of 30% alcohol and 1231mL of 95% alcohol
D. none

151. How many mL of 1:111.11 (w/v) Normal saline can be made from 20g of sodium chloride?
A. 2,222.22 mL C. 2.2 mL
B. 2000 mL D. 2002 mL

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152. Hercel, a manufacturing pharmacist bought 50 PG of spirits. How many wine gallons does this represent if
the purchase wa 70%?
A. 70 C. 25
B. 35.7 D. 35

153. It is a description of the chemical structure of the drug or medicine and serves as the complete
identification of a compound.
A. trade nameC. brand name
B. INN D. chemical name

154. The expiration date on a pharmaceutical container states “EXPIRES November, 2009” This statement
means that by December 1, 2008, the product will have lost:
A. 5% of its activity
B. 50% of its activity
C. Sufficient activity to be outside the USP-NF monograph requirements
D. 20% of its activity

155. The adult dose of a drug is 250 mg. What would be the approximate dose for a six-year old child? (use
Young’s rule)
A. 85 mg C. 125 mg
B. 60 mg D. 100 mg

156. The most accurate way of determining the correct pediatric dosage is by using the child’s size calculate in
terms of:
A. Sex C. Basal Surface Area
B. Apothecary System D. Body Surface Area

157. What kind of medication order is given by the physician to a pharmacist or nurse, usually by the phone,
when unusual circumstances arise?
A. PRN orders C. STAT orders
B. Verbal orders D. Standing orders

158. A package insert lists a drug for a neonate as being 10 mcg/kg/day. The age range for a neonate is
considered to be:
A. birth to 1 month C. 1 month to 1 year
B. 1 month to 6 months D. birth to 1 week

159. A physician’s order reads, “administer 0.9 g of chloral hydrate every 48 hours” How many grams
should be administered in 5 days?
A. 4.5 g C. 225 g
B. 45 g D. 2.25 g

160. How many drops would be prescribed in each dose of a liquid medicine if 15mL contained 60 doses? The
dispensing dropper calibrates 32 gtts/mL.
A. 8 drops C. 28 drops
B. 0.2 drops D. 2 drops

161. If the doctor says to take an allergy pill every 3 hours, how much time will go by between the 1 st pill and
the 4th pill?

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PHARMACEUTICAL CALCULATION – PACOP BLUE
A. 12 hrs C. 3 hrs
B. 6 hrs D. 9 hrs

162. The prophylactic dose of riboflavin is 2000 mcg. How many mg of riboflavin are in a capsule containing 3x
the prophylactic dose?
A. 6 mg C. 0.6 mg
B. 600 mg D. 6000 mg

163. A physician prescribes 0.15 mg q.d. of a drug. The drug is available as 0.05mg/mL. How many mL should
be administered?
A. 0.33 mL C. 3.3 mL
B. 3 mL D. 30 mL

164. You are directed to prepare 10 liters of a 1:5000 solution of KMnO 4. If the KMnO4 is available only in the
form of tablets, each containing 0.2 g, how many tablets should be used in preparing the solution?
A. 10 tabs C. 100 tabs
B. ½ tab D. 0.5 tab

165. B.S. Pharmacy 4-A class consist of 3 men and 57 women. Write a proper fraction (reduced to lowest
terms) the represents the number of men in the total class
A. 3/60 C. 1/2
B. 1/20 D. both A & B

166. Another common way of expressing milliliter.


A. cubic meter C. cubic centimeter
B. cubic millimeter D. cubic liter

167. 1 cm = ______ mm:


A. 100 C. 10
B. 2.54 D. 1

168. 1mg is ______ of a gram:


A. 0.1 g C. 0.0001 g
B. 0.001 g D. 0.00001 g

169. 10mL = _______ cc:


A. 1 C. 100
B. 10 D. 1000

170. 1 mcg is ________ of a gram:


A. 0.001 C. 0.000001
B. 0.0001 D. 0.1

171. Convert 35⁰C to ⁰F


A. 95.6 C. 95
B. 31.5 D. 31

172. Convert 98.6⁰F to ⁰C


A. 37 C. 37.5

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PHARMACEUTICAL CALCULATION – PACOP BLUE
B. 72.5 D. 72

173. ORDER: Ritalin 15mg p.o. q.d.


SUPPLY: Ritalin 10 mg tablets
GIVE: _______ tab/s
A. 1 ½ C. ½
B. 1 D. 0.5

174. Describe your action if no method of administration is written in a medication order:


A. ask the nurse
B. contact the physician for clarification
C. ask your manager
D. ask your patient

175. Five mg of morphine sulfate have been prescribed for a patient suffering from severe pain. If 15mg/mL
morphine sulfate are on hand, how many mL should be administered?
A. 3 mL C. 0.33 mL
B. 1/3 mL D. either b or c

176. A physician prescribed 0.3 g simethicone total daily to be administered in four equally divided doses.
Simethicone comes in 20 mg, 25 mg, 40 mg and 60 mg tabs. How many tabs, of which strength, should be
dispense per dose?
A. Three-25 mg tabs of simethicone per dose
B. Four-20 mg tabs of simethicone per dose
C. Four-25 mg tabs of simethicone per dose
D. Do not dispense, call and verify the dose to your senior pharmacist

177. How many liter of a 10% Lysol solution are needed to prepare 1 liter of a 3% Lysol solution?
A. 0.3 C. 300
B. 3 D. 3000

178. How much sterile water needs to be added to a gal of 65% isopropyl alcohol to make it a 50% solution?
A. 1.3 gal C. 0.77 gal
B. 0.3 gal D. 0.23 gal
179. The strength of a toxoid is generally expressed in terms of
A. unit C. TCID50
B. Lf unit D. LD50

180. If 250mL of alcohol weigh 203 g, what is its density?


A. 1.232 g/mL C. 0.812 g/mL
B. 80 g/mL D. 0.812

181. If a liter of sorbitol solution weighs 1285 g, what is its specific gravity?
A. 1285 C. 1.285 g/mL
B. 1.285 D. 0.78 g/mL

182. What is the percent concentration of cholesterol in a patient’s blood serum if the cholesterol level is
determined to be 260 mg%?
A. 260% C. 0.26%

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B. 26% D. 2.6%

183. A patient is determined to have 0.8 mg of glucose in each mL of blood. Expressed the concentration of
glucose in the blood as milligrams percent.
A. 0.8 mg% C. 0.08 mg%
B. 80 mg% D. 8 mg%

184. A glucose meter shows that a patient’s blood contains 125 mg% of glucose. Express this value as mg/mL.
A. 1.25 mg/mL C. 12 mg/mL
B. 12.5 mg/ mL D. 0.125 mg/mL

185. Calcium hydroxide topical solution contains 170 mg of calcium hydroxide per 100mL at 15⁰C. Express this
concentration as a ratio strength:
A. 1:0.588 C. 1:588
B. 1:5.88 D. 1:58.8

186. An adult accidentally swallowed 36 NaF (MWt.=42) tablets containing 2 mg of NaF per tablets. How many
mEq of sodium were ingested?
A. 1.71 mEq C. 3024 mEq
B. 0.78 mEq D. 7.8 mEq

187. The initial dose f a drug is 0.25 mg/kg BW. How many mg should be prescribed for a person weighing 154
lb?
A. 38.5 C. 0.0035
B. 19.25 D. 17.5

188. The rectal dose of sodium thiopental is 45 mg/kg of BW. How many mL of a 10% solution should be used
for a person weighing 150lb?
A. 3.068 mL C. 30.68 mL
B. 0.3068 mL D. 3 mL

189. If a pharmacist counted 40 drops of a medication in filling a graduated cylinder to the 2.5mL-mark, how
many drops per mL did the dropper deliver?
A. 16 gtts/mL C. 0.06 gtts/mL
B. 1.6 gtts/mL D. none of the above

190. A nasal inhaler contains 250 mg of propylhexedrine and 12.5 mg of methanol. How many grams of
propylhexedrine would be used in preparing 5000 inhalers?
A. 62.5 C. 625
B. 1250 D. 12,500

191. Some side effects of tagamet, a drug used to treat duodenal ulcers, are dizziness, diarrhea, muscular
pain, and a rash. Tests have indicated that approximately 1% of all patients treated with tagamet
experienced these side effects. If 500 people were treated with tagamet, how many people experienced the
side effects?
A. 5 C. ½
B. 50 D. 1

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192. A glycerin solution 25% (v/v) is available. An order calls for glycerin 1.5 mL/kg BW. How many mL will you
administer to a 143-lb patient?
A. 97.5 mL C. 24.38 mL
B. 390 mL D. 39 mL

193. The adult dose of Demerol is 50 mg. A child with a body surface of 0.6 m2 should received how much
Demerol?
A. 17.3 mg C. 144 mg
B. 2.88 mg D. 1.4 mg

194. In the apothecaries’ system of measurement, the basic unit of mass is the:
A. mg C. mcg
B. grams D. grains

195. Amoxicillin/ clavulanate potassium (Augmentin). Available dose 125 mg/5mL. The prescription reads “25
mg twice daily”. Patient dose = ______ mL Augmentin:
A. 25 C. 2.5
B. 5 D. 0.25

196. Digoxin (lanoxin) elixir. Available dose = 0.1 mg. The prescription reads 0.05 mg per mL. Patient dose =
______ mL Lanoxin:
A. 2 C. 0.005
B. 0.5 D. 0.05

197. Acetaminophen (Tylenol). Available dose = 120 mg. The prescription reads 0.06g per 0.5mL. Patient dose
= ______ mL acetaminophen:
A. 10 C. 3.6
B. 1 D. 3

198. Erythromycin. Available dose = 200 mg/5mL. The prescription reads 0.3g. Patient dose = ______ mL
Erythromycin:
A. 0.75 C. 7.5
B. 3.3 D. 7

199. Mr. Kool is unconscious, has a nasogastric tube, and has been prescribed enteric coated aspirin (325 mg)
to be given now. Your best intervention is to:
A. Crush the medication, endorse it to the nurse to administer it to Mr. Kool via his nasogastric tube
B. Instruct the nurse to give the medication rectally, since Mr. Kool is unconscious
C. Call the physician who prescribed the medication for a more appropriate prescription
D. Ask your senior pharmacist for advise

200. A transdermal patch is a popular way to deliver topical drug that has:
A. a short-lived effect C. a prolonged effect
B. no systemic effect D. a local effect

201. You are to dispense Gantrisin 1.5 g. The tablets you have labeled Gantrisin 0.5g. How many tablet/s will
you dispense?
A. 1 C. 2
B. 1 ½ D. 3

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202. A 6 month-old infant weighing 5 kg is prescribed 1 mg of morphine before surgery for a diagnostic test.
The recommended dose of morphine for an infant is 0.1mg per kg per dose. Is the prescribed dose of
morphine:
A. Safe
B. Unsafe

203. Ehra Beatrize is 9 yrs old and weighs 67 lb. The prescribed dose for erythromycin stearate is 20 mg/kg per
dose q.i.d. You have erythromycin stearate is 200mg/ 5mL in stock. Calculate the number of tsp of
erythromycin/ dose for Ehra Beatrize:
A. 1 tsp/dose C. 3 tsp/dose
B. ¾ tsp/dose D. 4 tsp/dose

204. JM, a 15 year old boy, weighs 98 lbs and is to receive an initial insulin dose for hyperglycemia and
ketonuria. The prescription reads, “regular insulin 0.1 U/kg SC q.i.d.” How many units of regular insulin
will JN receive at each dose?
A. 9.8 U/dose C. 45 U/dose
B. 4.5 U/dose D. 98 U/dose

205. Izzabella is to be placed on a hypothermia blanket when her temperature is equal to or greater than 39⁰C.
You have only farenheit thermometer. At what degree farenheit would you first place Izzabella on the
hypothermia blanket?
A. 71 C. 102.2
B. 39.4 D. 127.8

206. Willem is to begin triple antibiotic therapy if his temperature reaches, or goes higher than 102⁰F. Your
hospital only has thermometer that indicates temperature in celcius. At what celcius temperature would you
begin Willem\s antibiotic therapy?
A. 74.4 C. 56.7
B. 38.9 D. 24.7

207. How many mL each of purified water and an isotonic sodium chloride solution should be used to prepare
30mL of a 1% w/v isotonic solution of Fentanyl Citrate (E = 0.11)?
A. 3.67 mL of purified water & 26.33 mL of NaCl solution
B. 36.7 mL of purified water & 26.33 mL of NaCl solution
C. 26.33 mL of purified water & 3.67 mL of NaCl solution
D. 26.33 mL of purified water & 36.7 mL of NaCl solution

208. A prescription calls for 25 mollimoles of KCl. How many g of KCl (MWt=74.5) are needed?
A. 18.62 C. 1.865
B. 18.65 D. 1.8625
209. The strength of an official diluted acid is expressed as:
A. % w/v C. % v/v
B. % w/w D. % v/w

210. The strength of an official undiluted (concentrated) acid is expressed as:


A. % w/v C. % v/v
B. % w/w D. % v/w

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211. It is a method by which the “weighted average” percentage of a mixture of two or more substances of
known quantity and concentration may be easily calculated:
A. allegation alternate C. standard deviation
B. allegation medial D. ratio and proportion

212. It is a method by which we may calculate the number of parts of two or more components of a given
strength when they are to be mixed to prepare a mixture of desired strength:
A. allegation alternate C. standard deviation
B. allegation medial D. ratio and proportion

213. In the USP, the temperature for specific gravities in alcohol is:
A. 25⁰C C. 25⁰F
B. 15.56⁰C D. 15.56⁰F

214. A special glass bottle used to determine sp.gr.


A. hydrometer C. volumetric flask
B. pycnometer D. distilling flask

215. It is a factor that expresses how much heavier or lighter a substance is than water:
A. sp. gr. C. density
B. sp. vol. D. mass

216. It tells us how much greater (or smaller) in volume a mass is than the same weight of water:
A. sp. gr. C. density
B. sp. vol. D. mass

217. If 500mL of mineral oil is used to prepare a liter of mineral oil emulsion, how many g of the oil having a sp.
gr. of 0.87, would be used in the preparation of 1 gallon of the emulsion?
A. 217.3 g C. 435 g
B. 1646.48 g D. 574.71 g

218. How many mL of nonmedicated, flavored syrup base must be added to 1 pint of Ranitidine (zantac) syrup,
15 mg/mL, to change its concentration to 5 mg/mL?
A. 946 mL C. 3 mL
B. 1419 mL D. 6,622 mL

219. How many grams of potassium citrate (C6H5K3O7.H2O, MWt=324) should be used in preparing 500mL of
potassium ion elixir so as to supply 15 mEq of K+ in each 5mL dose?
A. 1.62 g C. 162 g
B. 2.43 g D. 243 g

220. Rigner’s solution contains 0.33 g of Calcium chloride per liter. Express the concentration in terms of mEq
of Calcium chloride (CaCl2.H2O, MWt=147) per liter.
A. 4.5 mEq/L C. 2.24 mEq/L
B. 6.73 mEq/LD. 8.98 mEq/L

221. A flavored potassium chloride packet contains 11.5 g of KCl (74.5). How many mEq of KCl are
represented in each packet?
A. 20.13 mEq C. 40.27 mEq

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B. 0.02 mEq D. 0.04 mEq

222. Calcium gluconate (C12H22CaO14, MWt=430) injection 10% is available in a 10 mL ampul. How many mEq
of Ca++ does the ampul contain?
A. 2.33 mEq C. 232.56 mEq
B. 4.65 mEq D. 23.65 mEq

223. Peppermint spirit contains 10% v/v of peppermint oil. What volume of the spirit will contain 75mL of
peppermint oil?
A. 7.5 mL C. 75 mL
B. 0.75 mL D. 750 mL

224. How many grams of drug substance are required to make 120mL of a 20% (w/w) solution having a sp. gr.
of 1.15?
A. 69 g C. 27.6 g
B. 0.69 g D. 0.27 g

225. If one tbsp is prescribed as the dose, approximately how many dose will be contained in one pint of the
medicine?
A. 16 C. 32
B. 22 D. 10

226. How much cod liver oil is necessary to make 2500 capsules each containing 0.33mL?
A. 825 mL C. 7.57 mL
B. 7,575 mL D. 757 mL

227. How many grams of sucrose are required to prepare 2L of a 4% solution?


A. 80 g C. 8 g
B. 0.80 g D. 800 g

228. The dose of a drug for children using the BSA method is based on:
A. weight and age C. height and age
B. weight and height D. age and sex

229. What is the percentage strength (v/v) if 250 grams of a liquid having a sp. gr. of 0.8 are added to enough
water to make 2 liters of the solution?
A. 8.89% C. 13.89%
B. 15.63% D. 10%.

230. A physician prescribes 60mL of penicillin containing 4,800,000 units. How many penicillin units will be
represented in each teaspoonful dose of the prepared suspension?
A. 400,000 units C. 320,000 units
B. 80,000 units D. 960,000 units

231. How many proof gallons are contained in 500 wine gallons of Diluted Alcohol NF that contain 49% (v/v) of
pure alcohol?
A. 245 C. 490
B. 510.20 D. 1020

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232. What is the molarity of a solution that is prepared by dissolving 10 g of KCl (MWt=74.5) in enough water to
make 500mL of solution?
A. 0.288 C. 0.258
B. 0.268 D. 0.168

233. The usual expiration date that should be placed on a parenteral admixture prepared in a hospital
pharmacy is:
A. 1 hour C. 48 hours
B. 24 hours D. 1 week

234. A pharmacist adds 2mL of Tobramycin injection (40 mg/mL) to 4mL of tobramycin ophthalmic solution
0.3%. The concentration of tobramycin in the final mixture will be ________ g/mL:
A. 0.15 C. 0.015
B. 0.092 D. 0.012

235. Administer 500mL of 0.9% NSS over 6 hours. The drop factor is 20 drops per mL.
A. 28 gtt/min C. 0.25 gtt/min
B. 0.0125 gtt/min D. 0.75 gtt/min

236. You are to give 600mL of solution over 12 hours. The drop factor=20 gtt/mL. You would give _____
gtt/min:
A. 360C. 6
B. 17 D. 0.83

237. If a prescription order requires25 g of concentrated HCl (density=1.18 g/mL), what volume should the
pharmacist measure?
A. 21.2 mL C. 0.5 mL
B. 29.5 mL D. 23 mL

238. What is the weight in kg of four quarts sulfuric acid (sp. gr. 1.84)?
A. 6.98 C. 5.96
B. 6.96 D. 5.98

239. A pharmacist receives a bill of goods amounting to Php 35,400, less a 5% discount for quantity buying and
a 2% cash discount for paying the invoice within 10 days. What is the net amount of the bill?
A. P 32,922 C. P 33,360
B. P 33,630 D. P 32,900

240. Convert 3 tsp to mL:


A. 10 mL C. 15 mL
B. 20 mL D. 45 mL

241. i.c. (inter cibos) means:


A. every meal C. between meals
B. every after meal D. after meals

242. APAP means:


A. as soon as possible C. acetaminophen
B. aspirin D. apply as soon as possible

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243. IVPB means:


A. intravenous push back C. intravenous piggy bank
B. intravenous parenteral back D. intravenous piggy back

244. NPO means:


A. nothing by mouth C. nutrition given by mouth
B. not per oral use D. note per order

245. ft. means:


A. fiat C. make
B. feet D. all of the above

246. In what proportion should a 20% zinc oxide ointment be mixed with white petrolatum (diluents) to produce
a 3% zinc oxide ointment?
A. 3:17 C. 17:10
B. 3:7 D. 3:20

247. Katriel, a registered pharmacist had 1 gal of Phenobarbital elixir. At different times, she dispensed Oi, 6
fluidounces, 4 fluidrachm, Oss, fluidounces iss, and 12 fluidounces. What volume, in fluidounces, of the elixir
was left?
A. 128 C. 120
B. 84 D. 44

248. You are directed to sterilize the Rx at a temperature not exceeding 105⁰C. Calculate the corresponding ⁰F
temperature:
A. 212 C. 220
B. 121 D. 221

249. Calcium gluconate comes in vial of 1 g per 10mL. The prescription indicates that you should give the
patient 320 mg of calcium gluconate. Calculate the number of mL per dose that your patient should have:
A. 3200 mL/dose C. 0.032 mL/dose
B. 3.2 mL/dose D. 320 mL/dose

250. Dr. Albelda prescribes Drug A – 0.875 g p.o. q 12 h for Mrs. Jazul. You have Drug A-875 mg in stock. How
many tablets should you give Mrs. Jazul?
A. ½ tab C. 2 tabs
B. 1 tab D. 1 ½ tab

251. Dr. Jane prescribes Diltiazem HCl 60 mg for Prof. Tubon. You have 0.03 g tablets in stock. How many
tablets should she receive?
A. ½ tab C. 2 tabs
B. 1 tab D. 1 ½ tab

252. A prescribe dosage reads “1000 mg Ciprofloxacin (Ciprobay) in a 24- hour period”. Ms. Rubin de Celis
has received 0.25 g. How many more mg must she tae to complete the prescribed dosage?
A. 0.75 C. 18
B. 7.5 D. 750
253. How many water should be added to 2500mL of 83% (v/v) alcohol to prepare 50% (v/v) alcohol?

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PHARMACEUTICAL CALCULATION – PACOP BLUE
A. 1650 C. 1506
B. 4150 D. 995

254. In a clinical study, the drug triazolam produced drowsiness in 30 of the 1500 patients studied. How many
patients of certain pharmacy could expect similar effects, based on a patient count of 100 patients?
A. 50 C. 2
B. 5 D. 4

255. The adult dose of a liquid medication is 0.1mL/kg of BW to be administered as a single dose. How many
tsp should be administered to a person weighing 220lb?
A. ½ tsp C. 1 tsp
B. 4 ½ tsp D. 2 tsp

256. If a dosage table for a prefabricated dug product indicates the dose for a patient weighing 110 lb is 0.4
mg/kg of BW, taken t.i.d. x 10 d, How many 10-mg tabs of the product should be dispensed?
A. 60 tabs C. 6 tabs
B. 2 tabs D. 20 tabs

257. Given a solution of potassium permanganate prepared by dissolving sixteen-0.2 g tablets in enough
purified water to make 1600mL: What is the percentage strength of the solution?
A. 1% C. 0.32%
B. 0.2% D. 0.18%

258. The prophylactic dose of riboflavin is 2 mg. How many mcg of riboflavin is in a multiple vitamin capsule
containing 1/5 the prophylactic dose?
A. 400 C. 1000
B. 2000 D. 40

259. Rx Dextromethorphan 15 mg/mL


Guaifenesin Syrup ad 240mL
Sig, 1 tsp q 4 h p.r.n. cough

How many milligrams of Dextromethorphan should be used in preparing the Rx?


A. 720 C. 36
B. 180 D. 144

260. Dr. Eloise prescribed Penicillin V Potassium, 500 mg q.i.d. x 10 d, how many mL of a suspension
containing 500 mg of Penicillin V Postassium per 5mL should be dispensed?
A. 20 C. 50
B. 200D. 500

261. Rx Cisapride 1mg/mL


Orasweet ad 120mL

How many 10 mg-tablets of Cisapride may be used in compounding the prescription?


A. 10-10 mg tabs C. 2-10 mg tabs
B. 12-10 mg tabs D. 5-10 mg tabs

262. Express the % concentration in ratio strength: (base on the prescription in # 261)

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PHARMACEUTICAL CALCULATION – PACOP BLUE
A. 1:100,000 C. 1:1000
B. 1:200 D. 1:2000

263. Mr. Ancell, a registered pharmacist weighed 475 mg of a substance on a balance of dubious accuracy.
When checked on a balance of high accuracy, the weight was found to be 445mg. Calculate the percentage
error in the first weighing:
A. 6.32% C. 93.68%
B. 9.36% D. 10.8%

264. It is accepted as the clinical standard for judging excessive weight and obesity and is defined as BW in kg
divided by the square of height measured in meters:
A. Body Surface Area (BSA) C. USP-NF
B. Basal Mass Index D. Body Mass Index (BMI)

265. If a patient has taken 96 doses, each containing 3.4 mg of active ingredient, how many gr of the drug has
he taken in all?
A. 5-1/50 gr D. a and b
B. 5-1/20 gr E. a and c
C. 5.02 gr

266. From the following formula for 100 capsules, calculate the amount of Phenobarbital needed to prepare 24
capsules
Belladonna extract………………1.0 g
Ephedrine sulfate………………..1.6 g
Phenobarbital…………………….32.0 g
Aspirin…………………………….32.0 g

A. 0.24 D. 48 g
B. 8.33 g E. none
C. 0.48 g

267. What is the volume of 1 lb (apoth) of nitric acid with a specific gravity of 1.40?
A. 324.29 mL D. 1.5 mL
B. 266.57 mL E. none
C. 0.71 mL

268. Portion of the prescription that gives the instruction to the Pharmacist.
A. Superscription D. Tanscription
B. Inscription E. none
C. Subscription

269. The drachm is a unit of measure under


A. metric system D. SI
B. household system E. none
C. apothecary system

270. One gallon is equal to


A. 4 quart D. a and b
B. 8 pint E. b and c

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PHARMACEUTICAL CALCULATION – PACOP BLUE
C. 32 fluidounce

271. If the drug is labeled 5 mg per sq.m., how much will be given to a patient with BSA of 0.65 sq.m?
A. 3.25 mg D. 4.45 mg
B. 7.69 mg E. none
C. 0.13 mg

272. If a physician prescribed Keflex, 125 mg QID for 10 days, how many mL of Keflex suspension containing
125 mg/5mL should be dispensed?
A. 1000 mL D. 250 mL
B. 750 mL E. none
C. 500 mL

273. If a medication order calls for ½ ft. Oz of an antacid, how many milliliters will be prepared?
A. 14.79 mL D. 14.18 mL
B. 30.00 mL E. none
C. 1.85 mL

274. One apothecary pound is


A. 12 ounces D. 15 ounces
B. 13 ounces E. 16 ounces
C. 14 ounces

275. Select the correct equivalent of 3 Kg.


A. 0.3 g D. 30,000 g
B. 3 g E. 0.003 g
C. 3000 g

276. Using a graduated cylinder a pharmacist measured 25 mL of a liquid. On subsequent examination using a
burette, it was found out that he had actually measured 23.5 mL, What is the percentage of error in the
original measurement?
A. 6.38% D. 6.00%
B. 9.00% E. none
C. 7.00%

277. If a pharmacist has 27 grams of a drug that will be used in a formula to make 1000 capsules, how many
milligrams of the drug will be in each capsule?
A. 0.027 mg D. 2.7 mg
B. 27 mg E. none
C. 0.27 mg

278. How many grams of potassium permanganate are needed to make this prescription?
Rx Potassium permanganate q.s
Distilled water ad 120 mL
Mft. 1:5000 sol
Sig, Use UD

A. 41.7 g D. 0.24 g
B. 0.024 g E. none

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PHARMACEUTICAL CALCULATION – PACOP BLUE
C. 1.0 g

279. How many milliliters of a 10% (w/v) silver nitrate solution would be needed to make 60 mL of 1:4000
solution?
A. 0.25 mL D. 0.025 mL
B. 0.15 mL E. none
C. 0.015 mL

280. The strength of a drug is 5 mg per each milliliter of liquid. How many milliliters must be administered to
give the patient 0.05 g of the drug?
A. 0.1 mL D. 100 mL
B. 1.0 mL E. none
C. 10 mL

281. The following is the formula for a medicated powder.


Bismusth subcarbonate 8 parts
Kaolin 15 parts
Magnesium oxide 2 parts

How many grams of magnesium oxide is needed to prepare 5 lb (avoir) of the powder?
A. 149.3 g D. 200 g
B. 130 g E. 181 g
C. 175 g

282. How many grams of KCl is contained in a 100 mL of a 10% solution?


A. 0.1 g D. 100 g
B. 1.0 g E. none
C. 10 g

283. Sodium valproate oral solution contains sodium valproate 200 mg/5mL. How many 30-ml bottles should be
dispensed for the whole course of treatment if 100 mg of the drug is to be taken twice daily for 2 weeks?
A. 1 D. 4
B. 2 E. 5
C. 3

284. The latin abbreviation of M.ft. is part of the


A. Superscription D. Transcription
B. Inscription E. none
C. Subscription

285. The latin abbreviation of O. for Octarius mean


A. gallon D. drachm
B. ounce E. minim
C. pint

286. OD can mean


A. in the right ear D. all of the above
B. in the left ear E. none of the above
C. once a day

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PHARMACEUTICAL CALCULATION – PACOP BLUE

287. If one tablespoonful is prescribed as the dose, approximately how many doses will be contained in 1 pint
of the medicine?
A. 59 D. 74
B. 94 E. none
C. 31

288. If 0.020 g of a substance is used in preparing 125 tablets, how many micrograms are represented in each
tablet?
A. 0.16 microgram D. 160 microgram
B. 125 microgram E. none
C. 0.16 microgram

289. How many grams of a drug substance are required to make 120 mL of a solution such that each
teaspoonful will contain 5 mg of the substance?
A. 120 g D. 1.2 g
B. 0.120 g E. none
C. 12 g

290. If U-100 insulin contains 100 units of insulin in each milliliter of suspension, how many milliliters must be
administered to give a patient 60 units?
A. 0.6 mL D. 1.67 mL
B. 6.0 mL E. 16.7 mL
C. 60 mL

291. The adult dose of erythromycin is 250 mg to be given four times daily. Calculate the dose for a child with a
BSA of 0.46 sqm.
A. 940 mg D. 115 mg
B. 543.5 mg E. 66.5
C. 432.5 mg

292. What is the BSA of a child weighing 14 kg and measuring 100 cm in height?
A. 0.60 sqm D. 0.63 sqm
B. 0.61 sqm E. 0.64 sqm
C. 0.62 sqm

293. 0.5% glacial acetic acid solution means


A. 0.5 g in 100 mL D. 5 mL in 100 mL
B. 0.5 mL in 100 mL E. 5 mL in 100 g
C. 5 g in 100 mL

294. The formula for Magnesium Citrate Oral solution calls for 30.5 g of anhydrous citric acid (C 6H8O7) in 350
mL of the product. How many grams of citric acid monohydrate may be used in place of the anhydrous salt?
Molecular weight: anhydrous citric acid = 192, citric acid monohydrate = 210.
A. 33.35 g D. 29.55 g
B. 27.88 g E. 32.6 g
C. 35.40 g

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PHARMACEUTICAL CALCULATION – PACOP BLUE
295. The cost of 30 tablets of an Calcium is Php 175, what should be the selling price per 30 tablets to yield a
40% gross profit on the selling price?
A. Php 175 D. Php 245
B. Php 113.75E. Php 300
C. Php 150

296. A patient received a prescription for an antibiotic with the instruction to take two capsules at first and then
one every six hours. The doctor specifies 29 capsules. How long will the treatment last?
A. 7 days D. 4 days
B. 6 days E. 3 days
C. 5 days

297. What volume of 95% alcohol is required to produce 5L of 75% alcohol?


A. 6.33 mL D. 3947 mL
B. 3.95 mL E. 3950 mL
C. 6330 mL

298. A medication order calls for 1500 mL of D5W to be administered over a 8-hour period. Using an IV
administration set that delivers 10 drops/mL, how many drops per minute should be delivered to the patient?
A. 31 drops D. 25 drops
B. 29 drops E. 23 drops
C. 27 drops

299. A solution contains 20 mg% of Ca ion. Express this concentration in terms of milliequivalents per liter.
A. 5 mEq/L D. 20 mEq/L
B. 10 mEq/L E. 25 mEq/L
C. 15 mEq/L

300. If Aluminum ion has an formula weight of 27, what is its milliequivalent weight?
A. 7 D. 10
B. 8 E. 27
C. 9

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