Delivers Simplicity and Sensitivity: Dedicated Chemiluminescence Imaging System

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DEDICATED

CHEMILUMINESCENCE
IMAGING SYSTEM

DELIVERS SIMPLICITY
AND SENSITIVITY
COMBINING SIMPLICITY
WITH SENSITIVITY
Despite chemiluminescence blotting being
a widely used technique to separate and
detect proteins, at Syngene we know that
when you’re imaging Westerns you are
looking for sensitivity equal to film.
Using the knowledge of chemiluminescence imaging that we’ve acquired over 35 years, we’ve
developed the GeneGnome XRQ dedicated chemiluminescence imaging system, allowing you to
easily produce picture perfect Westerns every time.

SIMPLE
Built on Syngene’s unique GeneGnome system, GeneGnome XRQ has an optimized short ‘camera to
sample’ distance, making it easy for you to perform rapid chemiluminescence imaging.

SENSITIVE
Featuring a high quantum efficiency, cooled CCD camera, GeneGnome XRQ ensures you can see faint
bands with minimal background on your blot images.

SMALL
The compact GeneGnome XRQ takes up minimal bench space,
allowing you more room for your experiments.

(Tablet not included)


“WESTERN BLOT IMAGING
HAS NEVER BEEN SO EASY”
UNIQUE
GENEGNOME
SYSTEM

ADVANCED LENS
Great imaging starts with a great
lens and this F/0.95 fixed focus lens
gives optimum image quality.

HIGH QUANTUM
EFFICIENCY CAMERA
The 4-megapixel resolution CCD
camera is very sensitive to low level
light emissions, producing images
of up to 16m pixels, allowing you to
see and separate those faint, close
bands on blots up to 11cm x 8cm.
The GeneGnome XRQ camera has
double the dynamic range of film
and with a quantum efficiency of
greater than 73% @ 425nm gives
outstanding sensitivity for
chemiluminescence imaging.

SUPER LOW COOLING


Peltier cooling with exceptional
signal to noise performance lets
you have long exposure times.
You can detect your weak and
strong chemiluminescent bands on
one crisp image, without any
annoying background noise.

WHITE LIGHT
To position your blots and detect
coloured markers, the GeneGnome
XRQ comes with overhead long-life
white LED EPI lighting.

SLIDE-OUT DRAWER
The automatic slide-out drawer
gives you more bench space and
allows you to easily position your
blot. Its magnetic lock ensures
that the darkroom is completely
light-tight, resulting in perfect
image capture every time.

PC CONTROL
GeneGnome XRQ easily integrates
to your choice of PC and printer
giving you the flexibility to run the
GeneSys touch screen controls on a
large screen, store a huge library of
images and rapidly print low
resolution or publication quality
pictures.
GENESYS
LOAD AND GO
IMAGING

Using GeneSys capture software, you can set up the GeneGnome XRQ to do single
auto-capture, series capture or manual capture of your Westerns to generate your
choice of one or a series of timed images.

BRIGHTER WESTERNS
When you’re imaging low light chemiluminescence Westerns you can use the GeneSys
binning feature to reduce exposure times. Binning combines pixels into larger formats
to produce a super pixel which collects more light, increasing sensitivity or speeding
up your image capture time.

PICTURE PERFECT
To produce a publication ready picture of your Westerns you simply choose
high-resolution images in the GeneSys software effective resolution settings.
You can even generate images of colorimetric molecular weight markers alongside
your chemiluminescent bands as GeneSys allows you to automatically overlay them on
your Western images.

FAST IMAGE ANALYSIS


The GeneGnome XRQ comes with GeneTools image analysis software which you can
use for applications such as automatically calculating molecular weight and relative
quantitation of protein bands. Using GeneTools you can also make your own image
edits and your data is easily saved as image files or can be exported to Microsoft
Excel and Word.

APPLICATIONS
A Western blot of diluted transferrin was prepared on a PVDF membrane.
The membrane was treated with SERVA Light Vega chemiluminescence substrate and
imaged using GeneGnome XRQ system.

Exposure time of
3 minutes was used.
Antibodies used: Prim AB
anti-trasferrin 1:1000
Sek AB anti-human 1:2000
0.01 µg/µl, 5 ng/µl, 2 ng/µl;
0.1 ng/µl; 0.05 ng/µl;
0.02 ng/µl; 0.01 ng/µl

Simultaneous imaging
of your chemiluminescent
blot and coloured
molecular weight
markers. Images are
captured separately and
then overlaid automatically
using GeneSys software
SPECIFICATION

SYSTEM GENEGNOME XRQ


Image resolution (megapixels) 4
Effective resolution (megapixels) 16
A/D 16 bit
Greyscale 65,536
Quantum Efficiency (@ 425nm) 73%
Lens (motor driven, fixed focus) F/0.95
Cooling Peltier
Fixed stage True lens imaging
Use with external PC and printer (not included) Yes

LIGHTING
Epi LED White Lights Yes

DIMENSIONS
Max image area (cm) 11 x 8
Min image area (cm) 11 x 8
W x H x D (cm) 37.5 x 44 x 43
Weight (kg) Approx. 20
Power Input (V) 100-240

More than 75,000 scientists world-wide use Syngene imaging systems to enhance their research. If you want your
Westerns to have a happy ending, then contact us or one of our dealers, for more information and a demonstration
of the GeneGnome XRQ and get away from the drama of using film.

Please refer to www.syngene.com for all ordering information

Syngene Europe and International Headquarters:


Beacon House Nuffield Road Cambridge CB4 1TF UK
Tel: +44 (0)1223 727123 Fax: +44 (0)1223 727101 email: [email protected]

Syngene USA Headquarters:


5103 Pegasus Court Suite L Frederick MD 21704 USA
Tel: 800-686-4407/301-662-2863 Fax: 301-631-3977 email: [email protected]

Website: www.syngene.com

All trademarks acknowledged G0060.12.12

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