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    Huntington's Disease: Pedigree Worksheet - Name

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    nonono
    1. The pedigree shows a family with Huntington's disease, which is dominant. Affected individuals are I1, II2, II3, II7, and III3. 2. Colorblindness is shown to be X-linked as females can be carriers without having the trait, and it is passed from father to daughter. Affected males are IV-1 and IV-5. 3. Hitchhiker's thumb is recessive as only 2 of 19 family members have it, with carriers being III-4 and III-5, and affected individuals being IV-2 and IV-4.

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    Huntington's Disease: Pedigree Worksheet - Name

    Uploaded by

    nonono
    3K views2 pages
    1. The pedigree shows a family with Huntington's disease, which is dominant. Affected individuals are I1, II2, II3, II7, and III3. 2. Colorblindness is shown to be X-linked as females can be carriers without having the trait, and it is passed from father to daughter. Affected males are IV-1 and IV-5. 3. Hitchhiker's thumb is recessive as only 2 of 19 family members have it, with carriers being III-4 and III-5, and affected individuals being IV-2 and IV-4.

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    pedigree_worksheet_-_key

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    1. The pedigree shows a family with Huntington's disease, which is dominant. Affected individuals are I1, II2, II3, II7, and III3. 2. Colorblindness is shown to be X-linked as females can be carriers without having the trait, and it is passed from father to daughter. Affected males are IV-1 and IV-5. 3. Hitchhiker's thumb is recessive as only 2 of 19 family members have it, with carriers being III-4 and III-5, and affected individuals being IV-2 and IV-4.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    3K views2 pages

    Huntington's Disease: Pedigree Worksheet - Name

    Uploaded by

    nonono
    1. The pedigree shows a family with Huntington's disease, which is dominant. Affected individuals are I1, II2, II3, II7, and III3. 2. Colorblindness is shown to be X-linked as females can be carriers without having the trait, and it is passed from father to daughter. Affected males are IV-1 and IV-5. 3. Hitchhiker's thumb is recessive as only 2 of 19 family members have it, with carriers being III-4 and III-5, and affected individuals being IV-2 and IV-4.

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    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
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    Pedigree Worksheet - KEY Name _______________________________

    I
    1 2
    = Huntington’s
    Disease
    II 1 2
    2 3 4 5 6 7 8

    III
    1 2 3 4 5

    1. Which members of the family above are afflicted with Huntington’s Disease? I1, II2, II3, II7, III3

    2. There are no carriers for Huntington’s Disease- you either have it or you don’t.
    With this in mind, is Huntington’s disease caused by a dominant or recessive trait? Dominant

    3. How many children did individuals I-1 and I-2 have? 6

    4. How many girls did II-1 and II-2 have? 2 How many of these daughters havehave Huntington’s Disease? 1

    5. How are individuals III-2 and II-4 related? Uncle/Niece I-2 and III-5? Grandma/Grandson

    6. The pedigree to the right shows a family’s pedigree


    for Hitchhiker’s Thumb. Is this trait
    dominant or recessive? Recessive
    I
    1 2
    7. How do you know? Because only 2 out of 19 people
    have it, making it rare.
    II
    8. How are individuals III-2 5 6
    1 2 3 4
    and III-3 related? Brother/Sister; siblings 1 4

    9. How would you name the 2 individuals that III


    1 2 3 4 5 6 7
    have hitchhiker’s thumb? IV-2, IV-4
    IV
    10. Name the 2 individuals that were 1
    carriers of hitchhiker’s thumb. III-4 and III-5 2 3 4

    11. Is it possible for individual IV-3 to be a carrier? Yes Why? parents are carriers, punnett square shows 50% chance

    12. The pedigree to the right shows a family’s pedigree


    **half-shaded = carrier of disease
    for colorblindness. Which sex can be carriers of I
    colorblindness and not have it? females

    13. With this in mind, what kind of trait is II


    colorblindness (use your notes)? X-Linked

    14. Why does individual IV-7 have colorblindness?


    Because her mom is a carrier and dad has it
    III
    15. Why do all the daughters in generation II carry the
    colorblind gene? b/c dad was affected and its on the X
    IV
    16. Name 2 generation IV colorblind males. IV-1, IV-5
    1 2 3 4 5 6 7 8
    Pedigree Worksheet KEY
    Genetics Pedigree Worksheet

    A pedigree is a chart of a person’s ancestors that is used to analyze genetic inheritance of certain traits –
    especially diseases. The symbols used for a pedigree are:

    female, unaffected male, unaffected

    female, affected male, affected


    Siblings are placed in birth order from left to right and are labeled with numbers.

    Each generation is labeled with a Roman numeral.
    o Example: we would name an individual II-3 if he/she was in the second generation and the 3rd
    child born
    ------------------------------------------------ ------------------------------

    I
    1 2 3 4 5 6

    II
    1 2 3 4 5 6 7 8 9

    III
    1 2 3 4 5 6 7 8

    Try to identify the genotypes of the following individuals using the pedigree above.
    (homozygous dominant, homozygous recessive, heterozygous)
     III-3: Homozygous recessive  I-1: Homozygous recessive
     II-1: Heterozygous  II-4: Heterozygous

    1. Is this trait dominant or recessive? Explain your answer.


    It is a recessive trait because generation II does not have the disease and Generations I and III do have it.

    2. How can you know for sure that individuals II-3 and II-4 are heterozygous?
    Because their offspring have the disease so they are both carriers of it.

    3. Do you think the cross above is sex-linked or autosomal? Explain your answer.
    It is autosomal because males and females seem to affected at the same rates. If it was sex-linked, it would mean
    that more males are affected.

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