Membrane Transport: Dr. Kevin Ahern
Membrane Transport: Dr. Kevin Ahern
Membrane Transport: Dr. Kevin Ahern
Transport
Symport
Uniport Antiport
(Synport)
No Net Change in Charge Net Change in Charge
Ion Channels
Ion Channel Features
1. General Structure
2. Opening
3. Filter
4. Effective Opening Size
5. Door
Closed Open
Potassium Channel
Potassium Channel - Top-down View
Hydration Shell
Cellular Transport Types
Sodium-Potassium ATPase
Secondary
Energy
Source
Sodium-Glucose Pump
Sodium/Glucose Symport
Lactose Permease
Lactose/Proton Symport
Lactose Permease
Secondary Energy Source - Protons
Voltage Change
Nerve Cell Transmission
1. Stimulus
2. Opening of Na+ gates
3. Na+ diffuses into cell
4. Voltage change causes K+ gates to open
5. K+ diffuses out of cell
6. All gates close
7. Wave of voltage changes moves down cell
8. Neurotransmitters move signal across cells
9. Na+ K+ ATPase restores gradients in originating cell
K+ gates open
Action Potential
Gates
Transmission of signal
from one cell to another
Tetrodotoxin
From Puffer Fish
Bind Voltage Gated Na+ Channels
Saxitoxin
Shellfish Toxin From Algal Blooms
Sodium Channel Blocker