1998 - Ehlers Et Al.
1998 - Ehlers Et Al.
1998 - Ehlers Et Al.
3, 1998
Not all patients with posttraumatic stress disorder benefit from exposure treat-
ment. The present paper describes two cognitive dimensions that are related
to inferior response to exposure in rape victims. First, individuals whose memo-
ries during reliving of the trauma reflected mental defeat or the absence of
mental planning showed little improvement. Second, inferior outcome was cor-
related with an overall feeling of alienation or permanent change following the
trauma. These results are based on blind ratings of transcripts of exposure treat-
ment sessionsfiom 10 women with good outcome and I0 women with inferior
outcome. Patients in the two groups were matched for initial synptom severiy
and were comparable in many aspects of the assault. Patients who experienced
mental defeat, alienation, or permanent change may require cognitive restnic-
turing in addition to exposure.
KEY WORDS: posttraumatic stress disorder; exposure treatment; predictors of outcome;
mental defeat; alienation.
This manuscript was accepted under the editorial tenure of Bonnie L. Green.
'Department of Psychiatry, University of W o r d , U.K.
'Department of Psychiatry, The Center for the Treatment and Study of Anxiety, Allegheny
University and Hahnernann University, Philadelphia, Pennsylvania 19129.
%o whom correspondence should be addressed at Department of Psychiatry, University of
Oxford, Warneford Hospital, Oxford OX3 7JX U.K. e-mail: ANKE.EHLERS @
PSYCHIATRY.OX.AC.UK.
457
Cadell, & Zimering, 1989) and it is widely believed that reliving is an im-
portant component of treatment. The exposure treatment developed by Foa
and colleagues (Foa, Rothbaum, Riggs, & Murdock, 1991) represents the
most systematic application of this therapeutic principle. Controlled trials
have demonstrated that exposure treatment is an effective treatment for
PTSD (Keane et al., 1989; Richards, Lovell, & Marks, 1994) and is more
effective than supportive counselling, and in the long-term, also more ef-
fective than stress inoculation training (Foa et al., 1991).
Although exposure treatment is effective, not all patients benefit from
this approach. For example, Foa et al. (1991) found that of the patients
treated with exposure 45% continued to meet diagnostic criteria for PTSD
and 44% failed to achieve clinically significant improvement at 3-month
follow-up. This raises the question of whether it is possible to identify fac-
tors that predict treatment outcome. The analysis of reasons for inferior
treatment response may also help in developing more effective treatment
procedures.
The present study was designed to explore cognitive differences be-
tween individuals who respond well to exposure and those who show less
marked improvement. Two clinical observations guided the search for pos-
sible predictors. First, we had observed that women who had been raped
differed widely in their reported thought processes during the trauma (see
also Burgess & Holmstrom, 1976). Some reported that they continued to
plan in their own mind how they could influence the situation (even though
these plans were often not successful) and retained a sense of psychoIogica1
autonomy despite the fact that the assailant could physically overpower
them. In contrast, others reported that they felt completely defeated during
the rape and did not feel they were a human being any longer. We expected
that while reliving the former experience should be therapeutic, repeatedly
reliving the latter experience without any cognitive restructuring may not
be.
Second, some patients report post-rape experiences that they perceived
to be negative. These experiences sometimes cause significant distress and
may be traumatic in their own right. We expected poorer outcome for these
patients because exposure treatment does not usually address post-trauma
experiences.
To assess the relationship of thought processes during trauma and post-
trauma experiences with treatment outcome, we obtained narratives of the
traumatic event (rape) from exposure treatment sessions of patients with
good and with inferior outcome. Based on a manual developed for the
purposes of this study, transcripts of these narratives were analyzed by rat-
ers who were blind to treatment outcome. Previous studies have also used
narratives to study variables related to treatment outcome. In contrast to
Mental Defeat and Alienation 459
the study reported here, the focus of those investigations has been on struc-
tural aspects of the narratives such as fragmentation of memories, and not
on the content (see Foa, Molnar, & Cashman, 1995, for results and a re-
view).
Method
Participants
Twenty women who had been sexually assaulted and received exposure
treatment in the context of a study investigating the efficacy of cognitive-
behavioral treatment for PTSD (Foa et al., 1994) comprised the sample
for the present study. Participants with good and inferior outcome were
selected on the basis of their PTSD symptoms at the beginning and end
of treatment, as assessed with the PTSD Symptom Scale (PSS; Foa, Riggs,
Dancu, & Rothbaum, 1993). Groups were matched for initial PSS scores.
Ten participants showed large improvement with treatment (good outcome
group); the other ten showed only modest improvement (inferior outcome
group). Half of the subjects in each group had received prolonged exposure
only (PE, seven sessions), the other half received stress inoculation training
in addition to six sessions of prolonged exposure (PE/SIT). Table 1 shows
participant and assault characteristics for the two groups. The groups did
not differ in age, ethnic background, marital status, education, employment,
pretreatment PSS, depression (Beck Depression Inventory, BDI, Beck,
Ward, Mendelsohn, Mock, & Erbaugh, 1961), anxiety (State-Trait Anxiety
Inventory, STAI-trait and STAI-state, Spielberger, Gorsuch, & Lushene,
1970), months since the assault, percentage of participants who thought
that they would be killed during the assault, percentage of assaults in which
a weapon was used, percentage completed rapes, relationship to assailant,
previous treatment, percentage of participants who reported child sexual
abuse, previous or subsequent rape, or treatment expectancy ratings. The
only significant difference between the groups was that the inferior out-
come group had experienced longer assaults than the good outcome group,
t (10.55) = 3.22, p = .009. As intended by the selection procedure, the
good outcome group showed a much larger reduction in PSS scores with
treatment than the inferior outcome group, Group x Time interaction, F
(1,18) = 11.71, p = .003. There were no effects of treatment condition
(PE vs. PE/SIT) or interactions. On the BDI and STAI, both the good and
inferior outcome groups improved with treatment, time effects, F (1,18) =
23.91, p < .001 for the BDI, F (1,18) = 12.78, p = .002 for STAI-trait, F
(1,18) = 6.88, p = .017 for STN-state.
460 Ehlers, Clark, Dunmore, Jaycox, Meadows, and Foa
Materials
Transcripts were obtained for each participant for one early and one
late exposure session. Anxiety ratings and any other possible indicators of
treatment outcome were deleted from the transcripts. The reason for
choosing one early and one late treatment session was that participants
vaned widely in how much information they included in the narratives of
the trauma. The postrape events in particular were sometimes only included
in either the early or the late session. Each session included between two
and three relivings.
Raters
Raters were two Ph.D. level clinical psychologists and two B.A. level
psychologists. The raters were blind with respect to treatment outcome.
Rating Manual
Results
Table 2 shows the mean ratings of the four raters for the good and
inferior outcome groups. Participants with inferior outcome received higher
scores on the Mental Planning/Defeat scale than participants with good
outcome, t (11.59) = 4.06, p = -002. The inferior outcome group showed
very little evidence of mental planning and approximately half experienced
mental defeat. None of the participants with good outcome were rated as
having experienced mental defeat and all of them reported evidence of
mental planning. There was a significant negative correlation between the
Mental Planning/Defeat scale and percent improvement in the PSS during
treatment, r(18) = -.66,p = .002.
Discussion
Percentage
change in PSS
Age .13
Months since assault (rho) -.I6
Duration of assault (r) -.49*
Ethnic group (Black vs. Caucasian, rho) .11
Marital status (singleldivorced vs. marriedco-habitating, rho) -.30
Employment (rho) .06
Years of education ( r ) .I5
Depression (BDI pre, r ) .06
Detachment from others (PSS item 9, rho) -.42"
Attempted vs. completed rape (rho) -.40**
Expectation to be killed (no vs. yes, rho) -.09
Presence of weapon during assault (rho) .06
Assailant stranger vs. known (rho) -.35
Previous treatment (rho) -.02
Child sexual abuse (no vs. yes, rho) .27
Previous rape/attempted rape (no vs. yes, rho) -.35
Subsequent rape (rho) -.26
Eupectancy-treatment logical ( r ) -.32
Expectancy-confidence self ( r ) .I6
Expectancy-confidence others ( r ) -.14
'y: Pearson correlation; rho: Spearman correlation; ' p < .05; **p < .lo.
the rape and especially those who felt completely defeated and lost the
sense of being a person with their own will responded less well to repeated
imaginal reliving of the traumatic event.
One may argue that giving up planning or experiencing mental defeat
during rape may reflect differences in other comorbid symptoms such as
depression, objective characteristics of the assault, or be due to previous
negative experience such as child sexual abuse. However, a large number
of possibly relevant patient and assault characteristics were assessed, and
the only significant difference between the groups was in assault duration.
Although the experience of mental defeat was correlated with duration of
the assault and relationship to assailant, its relationship with treatment out-
come could not fully be explained by these variables. These results make
it highly unlikely that the cognitive differences between the good and in-
ferior outcome groups were simply epiphenomena of objective differences
in trauma history. The analysis of correlation patterns with percent im-
provement in posttraumatic symptoms underscores this conclusion.
When interpreting the low correlations between assault and previous
trauma characteristics with PSS change scores, one has to bear in mind
that all the patients in the sample had experienced a very severe trauma:
466 Ehlers, Clark, Dunmore, Jaycox, Meadows, and Foa
the vast majority of the participants thought they would be killed, and
nearly all experienced completed rape. The impact of pre-rape experiences
and assault characteristics would probably be larger in samples with a wider
range of trauma severity. In addition, although many of the correlations
were nonsignificant, some were in the expected direction of a relationship
between overall severity of trauma history (e.g., previous and subsequent
rape) and outcome. It is possible that participants who had been raped
repeatedly and those who experienced longer assaults may have benefited
from a larger number of exposure sessions. However, the pattern of results
may also point to the need to distinguish between factors predicting the
initial occurrence of PTSD symptoms and those predicting chronicity of
symptoms or poor response to treatment (Ehlers & Steil, 1995; Rothbaum,
Foa, Riggs, Murdock, & Walsh, 1992).
There are several ways in which mental defeat/absence of mental plan-
ning may undermine the efficacy of exposure therapy. The experience of
mental defeat may impede recovery by preventing the patient from seeing
that the trauma was a single, time-limited, past event which does not nec-
essarily have global implications for oneself or one’s future. Reliving the
event in exposure therapy may be less effective and possibly retraumatizing
because the patient is repeatedly reminded of hidher inability to cope. This
may confirm some negative views the victim holds about herself (e.g., “I
am worthless,” “I deserved it,” “I am to blame for what happened,” “I am
disgusting,” “I am a bad person”) and about her ability to cope with future
adverse events or the symptoms triggered by the assault (e.g., “I am a lousy
coper,” “It will happen again and I will not be able to prevent it,” “Bad
things will always happen to me”). Reliving may thus fail to disconfirm the
belief that the traumatic event has serious implications for the future, and
maintain rather than change the patient’s sense of ongoing threat. In line
with our results, Pitman et al. (1991) observed that six veterans with PTSD
who experienced complications such as depression or relapse of alcoholism
during exposure treatment were characterized by negative appraisal of their
actions during the combat events they were exposed to. Repeated reliving
of the combat events seemed to confirm rather than change these negative
appraisals.
This raises a general issue about the use of exposure therapy in PTSD.
According to Foa and Kozak (1986) and Foa, Steketee, and Rothbaum
(1989), exposure therapy leads to the incorporation of new corrective in-
formation into the fear network. Foa and Jaycox (in press) have outlined
several ways in which this might occur in patients with chronic PTSD. Re-
peated reliving of the trauma lowers anxiety by habituation. Reliving of the
trauma in a safe environment incorporates safety information into the trau-
matic memory. Facing the trauma helps patients to discover they will not
Mental Defeat and Alienation 467
go mad or lose control and to distinguish the memory from present reality.
Finally, traumatic memories tend to be disorganized and repeated reliving
helps patients to construct a coherent narrative which assists in putting the
experience behind them. Exposure therapy was initially developed for the
treatment of phobias and obsessive-compulsive disorder. It may apply best
to those symptoms and cognitions connected with PTSD that most closely
resemble those in these disorders, namely those related to excessive per-
ception of danger. For example, a woman who was raped may think after-
wards “All men are dangerous.” Exposure may help change this cognition
in a way similar to changing a phobic’s belief “All dogs are dangerous.”
However, exposure may be less effective at changing cognitions related to
negative self-evaluation such as those targeted in this study. These cogni-
tions may need to be addressed directly with cognitive therapy procedures.
It remains to be investigated whether individuals who experienced mental
defeat during rape will respond better to a combination of exposure and
cognitive restructuring, to cognitive restructuring alone, or to a larger num-
ber of exposure treatment sessions than used in the present study. We
would hypothesize that the combination of these methods will be most ef-
fective because reliving the event facilitates the assessment and modifica-
tion of the idiosyncratic meaning of the trauma, and cognitive restructuring
may be most effective in changing cognitions related to negative self-evalu-
ation.
One may argue that the relationship between mental planning and
treatment outcome reflects the role of perceived uncontrollability which is
a crucial variable in determining the aversiveness of a negative event (e.g.,
Foa et al., 1989; Foa, Zinbarg, & Rothbaum, 1992; Mineka, 1985). Mental
planning can be understood as attempts to exert control over the situation
(see also Burgess & Holmstrom, 1976), even if the control was minimal or
symbolic, such as a patient not wanting to show the rapist that she was
crying. Lack of mental planning may therefore reflect the patients’ percep-
tion that the situation is totally uncontrollable. However, mental defeat may
go beyond uncontrollability. In the present study, there was no difference
between the groups in their ability to prevent the rape and 80% were con-
vinced they would be killed during the rape. All patients described feeling
helpless, hopeless, and humiliated. The difference seemed to be that those
with good outcome continued to retain a sense of autonomy. The impor-
tance of retaining a sense of personal autonomy may explain Resnick, Kil-
patrick, Dansky, Saunders, and Best’s (1993) finding that completely
uncontrollable events like natural disasters are less likely to lead to PTSD
than trauma inflicted by other people such as rape, physical assault, or
torture.
468 Ehlers, Clark, Dunmore, Jaycox, Meadows, and Foa
vent exposure to the emotions experienced during the trauma. Riggs et al.
(1992) have proposed that the activation of anger networks inhibits fear
responses which would be necessary to achieve changes in the fear network
representing the trauma.
In line with our finding of a relationship between alienation and treat-
ment outcome, several recent studies have obtained results suggesting post-
trauma social interactions that are perceived as negative hinder post-trauma
recovery in untreated victims of trauma. Davis, Brickman, and Baker (1991)
and Ullman (1996) found that reports of negative social interaction were
associated with poor adjustment. Dunmore et al. (1997) found that negative
appraisals of other people’s responses after assault distinguished between
individuals with persistent versus recovered PTSD.
The material used for the current study does not allow one to decide
whether patients who experienced alienation actually received more nega-
tive responses or less support from other people than patients who did not
feel alienated. However, the coding instructions for alienation emphasized
patients’ interpretations of others’ responses. Some patients seemed to be
unaffected by negative responses because they discounted them as not rele-
vant whereas others were very upset about similar instances. Furthermore,
some patients felt alienated because of sympathetic responses which they
interpreted as other people looking down on them. It is therefore likely
that the patients’ interpretation of others’ responses plays a crucial role. It
is also likely that beliefs patients hold about what response they can expect
from others will actually have an impact on their social interactions in that
it will influence their behavior and thus the response they will receive from
other people. When interpreting the results of the present study, one has
to bear in mind that the inferior outcome group did not represent treat-
ment failures because they also showed improvement with exposure. Com-
pared to the good outcome group, however, their progress was much less
impressive. Thus, the predictor variables should be interpreted as impeding
rather than preventing therapeutic change during exposure.
Acknowledgements
The research described in this paper was funded by the Wellcome Trust
and a grant from the National Institute of Mental Health (MH42178). We
would like to thank Chris Molnar and Jane Stafford for their help with
data collection, Karen Bogert for helping produce the transcripts, and
Sarah Durbin and Fiona Lobban for rating the transcripts.
470 Ehlers, Clark, Dunmore, Jaycox, Meadows, and Foa
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