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THE RETINA

Baghdad University
College of Medicine
Department of Surgery
Ophthalmology Division
Objectives
The students should be able to:
 Describe applied anatomy of the retina.

 Define, list the types and causes of retinal detachment, describe


clinical symptoms and signs and differentiate between different
types.
 Outline the treatment of different types of retinal detachment.

 State the pathogenesis, classification, complications and


treatment of diabetic retinopathy.
 Define, state the clinical features, risk factors and treatment of
age related macular degeneration.
The retina
Anatomy:
Blood supply:

 - The outer one third (1/3) of retina (including RPE,


photoreceptors and half of the outer nuclear layer)
 - The inner 2/3 of retina
Blood-Retinal Barrier (BRB):

1-Outer BRB:
2-Inner BRB:
Applied anatomy:

 1- The macula:
 2- The fovea:
 3- The foveola:
 4- Umbo
Macula

1.5 mm 1 disc
Ø

3 mm
Fovea

FAZ 300-500μm

4 mm
Applied anatomy:

 1- The macula:
 2- The fovea:
 3- The foveola:
Retinal Detachment (RD)
Types of retinal detachment:
 1- Rhegmatogenous RD: (Rhegma = break)

 2- Non-rhegmatogenous RD:
a- Tractional RD:
b- Exudative (serous) RD:
1- Rhegmatogenous RD
 Causes:
 a- Idiopathic.
 b- Myopia.
 c- Trauma.
 d- Intraocular surgery, e.g. cataract surgery.
 e- Hereditary diseases of vitreous and retina, e.g. Stickler's
syndrome.
 f- In association with Tractional RD.
1- Rhegmatogenous RD
 Symptoms:
 a- Photopsia (flashes of light): PVD
 b- Floaters:
 c- Peripheral visual field defect:
 d- Decreased central visual acuity (drop
vision):
Posterior vitreous detachment
PVD
Rhegmatogenous RD
1- Rhegmatogenous RD
1- Rhegmatogenous RD
1- Rhegmatogenous RD
1- Rhegmatogenous RD
1- Rhegmatogenous RD
2- Non-rhegmatogenous RD:
a- Tractional RD:
 Causes:
 i- Proliferative diabetic neuropathy.
 ii- Retinopathy of prematurity "ROP"
(retrolental fibropathy or fibroplasias):
 iii- Sickle cell retinopathy.
 iv- Penetrating trauma.
2- Non-rhegmatogenous RD:
a- Tractional RD:
2- Non-rhegmatogenous RD:
a- Tractional RD:
Symptoms of tractional RD:

i- Visual field defect:


ii- Decreased central visual acuity:
2- Non-rhegmatogenous RD:
a- Tractional RD:
 Treatment: Vitrectomy
2- Non-rhegmatogenous RD:
b- Exudative RD:
Causes:
i- Choroidal tumours.
ii- Retinblastoma.
iii- Uveitis (posterior uveitis).
iv- Posterior scleritis.
v- Malignant hypertension.
vi- Eclampsia.
2- Non-rhegmatogenous RD:
b- Exudative RD:
Symptoms:
Photopsiae are absent. Why??
Floaters.
Visual field defect develops suddenly & progress rapidly.
Bilateral eye involvement is possible.

Treatment???
Diabetic Retinopathy
 Pathogenesis:

either microvascular occlusion.


Or microvascular leakage.
Vascular endothelial
groth factor (VEGF)v
Diabetic Retinopathy
 The consequences of leakage and increased
vascular permeability include the development of
intraretinal haemorrahges and oedema.
Diabetic Retinopathy
 Clinically DR may be:
 1- Background DR.
 2- Pre-proliferative DR
 3- Proliferative DR.
 4- maculopathy, which associates (1), (2) or (3).
 5- Advanced diabetic eye disease.
Diabetic Retinopathy
Diabetic Retinopathy
Age-Related Macular Degeneration
(AMD)
 A common, chronic, progressive degenerative
disorder of the macula that affect peoples above
50.

 dry AMD
 wet AMD
Macula

1.5 mm 1 disc
Ø

3 mm
Risk factors
• Age
• Race -Caucasians.
• Family history
• Smoking
• Hypertension and other cardiovascular risk factors
• Obesity and high fat intake
• Sun exposure, female gender and blue iris colour are
suspected
Symptoms
 Gradual and progressive painless loss of vision
 Decreased reading ability
 Positive scotoma
 metamorphopsia
 Sudden deterioration of vision
Amsler Grid
Dry AMD
Dry AMD
Treatment

Antioxidant vitamins and


minerals

Intravitreal antiVEGF

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