SLE4000

Infant Ventilator with

touch-screen operation

When the smallest thing matters

SLE4000 - The Total Solution for Conventional Infant Ventilation
SLE is a world leader in the design and manufacture of neonatal ventilators. Years of
ventilation experience have given the company an understanding of the challenges
facing clinicians when caring for the tiniest and most critical babies.
The knowledge and experience gained during years of development is evident in the SLE4000 ventilator; the result of
SLE’s ongoing commitments to innovation, competency and care.
Modes include: CPAP, CMV+ TTV, PTV, PSV, SIMV+ TTV + PSV
• Ability to preset parameters in all modes of operation
• Full colour, total touch-screen operation
• Integral flow monitoring measuring lung mechanics and displaying of loops and waveforms
• Trending of measured parameters
• Standard patient circuit for all modes (Except with NO therapy)
• Unique, patented valveless technology
• Integral battery with up to 60 minutes operating capability
• Software based, allowing for upgrading to versions with new or improved functions
Advanced Ventilator Features
Targeted Tidal Volume plus (TTVplus)
The SLE4000 features TTVplus - an entirely new way of managing the
patient’s tidal volume.
Lung protective ventilation strategies in neonates are now accepted as a
marker for improved ventilation outcome. One such strategy is the use of a
targeted tidal volume in pressure ventilation. The aim of TTVplus is to deliver
a stable tidal volume at the lowest possible pressure. All this has to occur
in the presence of a changing lung environment, that also has a potential
for a variable leak around the ET tube.
TTVplus approaches this challenge by assuring a stable expired volume,
with a leak adjustment capability within safe limits. TTVplus can be used
in all conventional ventilation modes and provides a stable tidal volume
control according to your patients’ requirements.

Pressure Support Ventilation (PSV)

PSV was developed on the SLE4000 as a method to decrease the work of
breathing between ventilator mandated breaths by providing an elevated
pressure triggered by spontaneous breathing, that supports ventilation
during inspiration. In addition, SIMV might be combined with PSV so that
additional breaths beyond the SIMV programmed breaths are supported.
Whilst the SIMV mandated breaths have a preset volume or peak
pressure, the PSV breaths are designed to cut short when the inspiratory
flow reaches a percentage of the peak inspiratory flow (e.g. 0 - 50%).
It includes automatic leak compensation thereby ensuring the flow
termination of inspiration even in the presence of a leak.
All of this means that breathing on the SLE4000 ventilator is even easier
Without flow termination With flow termination
for the smallest of babies, allowing them to use their energy to grow.

Respiratory Mechanics Measurement

Loops and waveforms allow the clinician to monitor and adjust ventilator
strategy.
• Real-time lung dynamics
• Loops can be displayed in real time or frozen
• Breath-by-breath display of resistance, compliance and C10/C values
 Quality Build
The SLE4000 case is manufactured in a unique solid cast
polyurethane moulding. This tough material is ideal for use in a
busy neonatal unit and easily withstands the knocks and bumps
of everyday life.

Integral screen
Colour-coded user touch screen. Easy-to-use, logical
sequence allowing quick, smooth adjustments.
The SLE4000’s 12.1 inch screen means that all the data
you need can be easily seen.

Real-time Data Display

Real-time lung mechanics measurements and ventilatory data.
This allows for continuous feedback for making crucial clinical
decisions.

Audible and Visual Alarms

The alarm panel provides an immediate audible
and pictorial view of the alarm condition, thus
allowing easy monitoring, plus an alarm history of
the last 100 conditions.

User Interface
Brightly coloured user touch screen. Easy-to-use with a
logical sequence allowing quick, smooth adjustments.
Parameters can be preselected for the next mode
whilst continuing to ventilate the patient in the
current mode of ventilation.

Compact Unit
The SLE4000 ventilator is housed in a single
compact box, making it easier to clean and use.
The integrated touch screen is angled for perfect
visibility and easy to read from a distance.

Patient Circuit Connections

Front panel mounted patient circuit connections
with (autoclavable) exhalation block.

Principles of operation of the SLE4000 valveless system

A constant flow of fresh gas is supplied to the patient circuit at 8 l/min. The expiratory manifold has three jets (➊, ➋ and
➌. The front jet (➊) is used to generate an opposing flow to the fresh gas in the exhalation manifold and thereby creates
CPAP/PEEP.
The rear jet (➋) is used to generate the Peak Inspired Pressure (PIP) in the same way.
A third (reverse) jet (➌) is used to help eliminate excess circuit pressure.
To avoid gas dilution these jets are supplied with the same oxygen concentration as the fresh gas supply. Sophisticated
software controls the rate and duration of the flow of driving gas into the exhalation manifold in opposition to the fresh gas
flow. The opposing flow acts as a pneumatic piston and creates a pressure wave at the ET manifold.
Since the opposing flow pressure is set by pressure regulators it automatically compensates for patient and circuit
compliance changes.
How does it work...?
The illustration shows the exhalation block removed
from its mountings in the ventilator. When replaced,
the jets (➊ and ➋) create a positive pressure on
flow from the patient circuits’s expiratory limb. ➌ ➋ ➊
Jet ➌ is used to create a negative pressure and
helps reduce excess circuit pressure.
Since there are no valves or other blockages in the
system, there is mnimal resistance to the patient.
Fewer moving parts means there is less to clean
and less risk in terms of wrong assembly or To exhaust port From expiratory limb

infection. Exhalation block

SLE4000 Patient Circuits
BC5188/100/15
Single use breathing circuit for use with SLE4000 (and SLE5000)
infant ventilators. Temperature port 100 mm from ET manifold (single
use). Circuit comes complete with filter connection kit and adaptors.

Sold in box quantity of 15

BC5188/400/15
Single use breathing circuit for use with SLE4000 (and SLE5000)
infant ventilators. Temperature port 400 mm from ET manifold (single
use). Circuit comes complete with filter connection kit and adaptors.

Sold in box quantity of 15

BC5488/DHW/15
Dual heated wire smooth bore breathing circuit for use with SLE4000
(and SLE5000) infant ventilators. Temperature port 170 mm from ET
manifold (single use). Circuit comes complete with filter connection kit
and adaptors.

Sold in box quantity of 15

BC6216
Nitric Oxide delivery kit, set of connectors.

BC2508
Nebuliser kit.

BC4110/KIT
Nitric Oxide adaptor kit for BC5188/100 and BC5188/400 breathing
circuits (SLE4000 (and SLE5000) infant ventilators).
Sold in box quantity of 5

BC4110/ASY
Nitric Oxide dual hose scavenging filter assembly for SLE4000 (and
SLE5000) infant ventilators.
Sold in box quantity of 1
Technical Specification
Ventilation Modes Oxygen Concentration Power, Dimensions, Standards etc.
CPAP / PTV / PSV Range: 21 to 100% Power Requirements
Inspiratory Time: 0.1 to 3.0 sec (Resolution 1%) Voltage : 100-250 V
CPAP Pressure: 0 to 20 mbar 50-60 Hz
Inspiratory Pressure: 0 to 65 mbar Pressure Power : 115 VA
Volume Targeting: 2 to 200 ml Real-time Pressure Battery back up: 45-60 minutes
Oxygen: 21% to 100% measurement: Resolution 1 mbar dependant on mode of operation
Sampling time: 2 ms Battery Charging: Full charge 24
CMV / SIMV Peak Pressure: 0 to 175 mbar hours, 80% charge after 8 hours
BPM: 1 to 150 (Resolution 1 mbar)
I:E Ratio: (11.2:1 to 1:600) PEEP Pressure: 0 to 175 mbar Outputs
Inspiratory Time: 0.1 to 3.0 sec (Resolution 1 mbar) RS-232C
PEEP Pressure: 0 to 20 mbar Mean Pressure: -175 to 175 mbar
Inspiratory Pressure: 0 to 65 mbar (Resolution 1 mbar) Air and O2 input
Volume Targeting: 2 to 200 ml Pressures: 2.8 - 6 bar
Oxygen: 21% to 100% User Settable alarms
High Pressure Fresh Gas Flow: 8 l/min
Monitoring Parameters Autoset when patient pressure controls are
Measurement of Flow and Volume adjusted or can be manually adjustable Maximum gas flow: 60 l/min
Flow Sensor Type: 10 mm dual-hot- Range: 10 to 110 mbar
wire anemometer (autoclavable or single Resolution: 0.5 mbar Operating Environment
use) Temp: 10-40 ºC
Flow Rate: 0.2 to 32 l/min Cycle Fail Humidity: 0-90%
(Accuracy 8%) Autoset when patient pressure controls are (non-condensing)
Expiratory Tidal adjusted or may be manually adjusted
Volume: 0 to 999 ml Dimensions
Expiratory Minute Low Pressure Size, ventilator only: 330mm W x
Volume: 0 to 18 litres Autoset when patient pressure controls are 330mm H x
Deadspace: 1 ml adjusted or can be manually adjusted 470mm D
Weight: 10 g Range: -10 mbar
(Conventional) Height on trolley: 131 cm
Conventional Ventilation and -70 mbar
combined modes only: Weight, ventilator only: 22.1 kg
Tube Leakage: 0 to 99% Low Tidal Volume
(Resolution: 1%, averaged over 10 breaths) Range: 0 to 200 ml Constructed to conform to:
Breath Rate (total): 0 to 250 BPM Resolution: 0.2 ml BS EN 60601-1:1990
Dynamic Compliance: 0 to 100 ml/mbar BS EN 60101-1-2:2001
(Resolution: 1 ml/mbar) Low Minute Volume BS EN 60601-1-4: 1996
C20/C: Resolution 0.1 Range: 0 to 0.02 litres BS EN 60601-2-12:2006
Sampling Time: 2 ms below High Minute Medical Devices Directive (93/42/EEC)
Resistance: 0 to 1000 Volume threshold
mbar.second/l Resolution: 0.1 litre European conformity mark: CE 0120
Triggering: Inspiratory flow
(0.2 to 10 l/min) High Minute Volume Environmental storage conditions
Range: 0.02 to 18 litres When packed for transport or storage:
Above values are measured under ATPD (Ambient
Temperature and Pressure, Dry) conditions
Resolution: 0.1 litre
Ambient Temperature: -40 °C to +70 °C
Apnoea time Relative Humidity : 10% to 90%
Settable only in CPAP or when Backup (non-condensing)
rate less than 10 BPM
Range: 5 to 60 sec Atmospheric Pressure: 500 hPa to
Resolution: 1 second 1060 hPa
 SLE is a world leader in the design
and manufacture of neonatal
ventilators.
Years of ventilation experience
have given the company an
understanding of the challenges
facing nurses and clinicians when
caring for the tiniest and most
critical babies.
From being the pioneers of
neonatal Patient Triggered
Ventilation (PTV) in the 1980’s, to
the introduction of combined HFO
(High Frequency Oscillation) in
the 1990’s, SLE has maintained
a position of strength in neonatal
ventilation.
The company’s guiding principle is
to support clinical and nursing staff
in their everyday work.
The knowledge and experience
gained during years of
development is evident in the
SLE4000 ventilator: the result of
SLE’s ongoing commitments to
innovation, competency and care.

G0007/0UK/001 07/13

SLE Limited.
Twin Bridges Business Park, 232 Selsdon Road,
South Croydon Surrey CR2 6PL UK
Telephone:+44 (0)20 8681 1414 • Fax: +44 (0)20 8649 8570
E-mail: [email protected] • Web: www.sle.co.uk www.sle.co.uk