DR Ayesha - S Notes For PLAB 2
DR Ayesha - S Notes For PLAB 2
DR Ayesha - S Notes For PLAB 2
Constipation
1 Intestinal Constipation, vomiting, Pain abdomen
obstruction
2 Bowel cancer Change in the bowel habit, Altered bowel habit, blood
in the stool, Tenesmus ( feeling of opening the bowelbut
nothing comes out when trying to open bowel), pain
abdomen, weight loss, loss of appetite, family history,
smoking, anaemiasymptoms
3 Medication Codeine, Morphine, Antacids, Anti-epileptics, Anti-
depressants,
Calcium, Iron
4 Anal fissure Pain in the back passage on defaecation, fresh blood
sticking to the stool
Dr Examination:
I need to examine your tummy and your back passage. ( examiner may say hard
stool felt in the rectum).
Diagnosis:
Mrs Thompson, I think the Co -codamol medication what you are taking for
pain is causing this constipation because one of the side effects of co-codamol
is constipation.
Treatment:
First of all we will stop giving this medication and we will give you some
other medication which will not cause constipation - maybe we will give you
Paracetamol if you are not in that much pain now.
We can give you some laxatives like senna, bisacodyl and sodium pico-
sulphate to help you to open your bowel.
You should drink plenty of fluids and eat high fibre diet like fruits and
vegetable or whole wheat bread. That will help you to open bowel.
Dr: We can give you some medication like Bisacodyl as Suppository – this
type of medicine is inserted into your back passage.
Pt: What if that also does not help ?
Dr: Then we can give enema where a medicine like Docusate andsodium
citrate in fluid form is injected through your back passage into your large bowel.
Headache – GCA
67 year old lady Mrs Melinda Jones presented to the hospital with headache. Take
history from her and discuss the management with her.
AACG ( acute angle Do you see coloured circles around light? Worse in
closure glaucoma) darkness? Redness of eye? Flashes
GCA Jaw claudication-Do you get pain on chewing?
[temporal artery] Temporal tenderness-pain while combing or touching
temple area? Any vision problems ( shade coming in front
of the eye, vision loss later)
Head injury [bone] By any chance you got hurt on your head?
Meningitis[meninges] Fever, vomiting, Photophobia-feel discomfort on bright
light? Rash-any rash in your body?
Neck stiffness-difficulty in moving your neck?
SAH[Below meninges] Sudden onset, meningeal signs but no fever.
Patient gives Hx of Pain on the sides of head while combing hair and pain in the jaws
while eating. No vision problems. No - Family history. Ask about severity of pain ( if
very severe – offer pain killers)
Management
Mrs Jones with what you told me I suspect you have a condition what we call as Giant
cell arteritis. Do you know anythingaboutthis? Pt – No
Dr: It is a condition in the blood vessels, usually in the head and neck, become inflamed.
It is sometimes called temporal arteritis because the arteries around the temples are
usually affected.
Pt: What are going to do for me?
Dr: We will do some blood tests to check for the possibility of this condition. (ESR and
CRP).
We need to do another test called temporal artery ( blood vessel on the side of the head)
biopsy to confirm the diagnosis. During the procedure, a small sample of your temporal
artery is removed and checked in the laboratory. It can take several days to get the
results of a biopsy.
However, we need to treat you urgently before we can do the biopsy because if we
delay the treatment waiting for the test result sometimes people can lose their vision
which can be permanent. To prevent the loss of vision we need to treat you immediately.
Do you follow me?
Pt: Yes. How will you treat me?
Dr: We will treat you medication called Prednisolone tablets which is a steroid.
Initially we will give high dose steroids ( 60mg ) which will gradually be reduced every
two to four weeks, depending on how well you respond totreatment.
If the diagnosis is confirmed with the biopsy - you may need to take prednisolone for up
to two years to prevent your symptoms returning. Your symptoms should improve
significantly within a few days of starting treatment. However, there is a chance they
will return (relapse) once treatment stops.
Please don't suddenly stop taking steroid medication because it can make you feel very
ill.
There are some side effects of steroids because you may need to take it for long time.
Do you want to know about them?
Pt ; Yes doctor.
Dr: It can cause changes in mental state - you may feel very depressed and very
anxious, or very confused.
It can also cause increased appetite, which often leads to weight gain
increased bloodpressure
mood changes, such as becoming aggressive or irritable withpeople
weakening of the bones(osteoporosis)
stomachulcers
increased risk ofinfection
The risk of these side effects will be lesser as your dosage of prednisolone is decreased.
We will also give you another medication called Aspirin in low dose ( 75mg daily).
This prevents complications of giant cell arteritis, such as heart attacks or stroke.
We will give another medication called Omeprazole to protect your stomach
from stomach ulcers.
We may also give some other medication called immune-suppressants, such as
methotrexate to suppress the immune system (the body's defence against infection and
illness). This can help prevent the condition recurring.
We will follow you up regularly to see how you are responding and to reduce the dose
of prednisolone.
We will issue a steroid card which you need to carry with you at all times as it will
explain that you are regularly taking steroids.
Pt: Will there be any complications ?
Dr: Sometimes it can causeVisual loss or heart attacks or stroke. However Aspirin
medication lowers the chances of getting these problems.
Another complication sometimes can happen is a condition called Polymyalgia
rheumatic which causes inflammation of the muscles and joints and causes neck and
hip pain, and stiffness of the affected muscles (which is often most obvious after waking
up).
Any other concerns ?
Pt: No
Dr: Thank you very much. Hope you will recover soon.
Dr: Hello Mrs Joan, I am Dr…. one of the junior doctor in the medical department.
Can you please tell me what brings you to the hospital?
Pt: I am having severe headache.
Dr: I am very sorry to hear that. Can you please tell me how severe is the pain – in the
scale of one to ten one being the mildest pain and ten being the most severe pain ?
Pt: It is 10 out of 10 doctor.
Dr: Do you want me to give you some pain killers ?
Pt: Yes please doctor.
Offer pain killer.
Dr: Can you please tell me more about your headache ?
Pt: Doctor this headache started suddenly. This is the worst headache of my life. I felt
it like thunder clap / I thought someone hit the back of my head.
Dr: Do you mean to say you used to have headaches like this before ?
Pt: Yes doctor, I have migraine.
Dr: Is this different than migraine headache ?
Pt: Certainly doctor. I never had headache like this before.
Dr: Where exactly in the head you have this headache.
Pt: Back of my head doctor.
Dr: Since when are you having this headache ?
Pt: Almost 2 hours now.
Dr: What were you doing when you got this headache ?
Examination:
Dr: Mrs Joan I need to examine you now and check your pulse and Blood pressure.
Examiner says – examination is normal. Her BP is 150/90, Pulse normal
10
Dr: Mrs Joan, I think you have a condition what we call as Subarachnoid
haemorrhage -that is bleeding in the brain. Are you following me?
Pt: Yes, but why do I have that doctor?
Dr:There are several reasons why this can happen. This usually happens because there
is some abnormal blood vessels in the brain which blood vessels becomes thin and
they bulge out what we call as aneurysm. Sometimes these blood vessels suddenly
rupture and cause severe headache like what you had. Sometimes this condition can
run in the family. Unfortunately this is a very serious condition and sometimes this
could be even life threatening. Do you follow me?
Dr: We will do Lumbar puncture which is usually done after 12 hours of oncet of
headache to look for Xanthochromia ( Lumbar puncture should ideally take place
over 12 hours after the onset of the headache because if there are red cells in the CSF,
sufficient lysis will have taken place during that time for bilirubin and
oxyhaemoglobin to have formed - xanthochromia (yellow discolouration of the
spinal fluid ).
Examiner says : What will you do if the Lumbar puncture is positive for SAH ?
Dr: We will admit her in the ITU and transfer to the neurosurgical ward.
Do further investigations to find out the exact location shape and size of the abnormal
blood vessels like
CTAngiography
Magnetic Resonance Angiography(MRA)
ECG
- Hydrocephalus,
- Delayed cerebralischaemia
If the blood sugar is very high, it causes the blood vessels which supplies blood to the back
of the eye called retina gets bulged out and it can start leaking blood. Sometimes new tiny
blood vessels get formed at the retina which easily gets damaged and starts bleeding. This
is called Diabetic retinopathy. This can cause vision problem. If the condition continues
then it can cause loss of vision.
Dr: Usually in early stages of Diabetic retinopathy - it does not require any treatment.
Controlling sugar will delay the condition getting worse. Whatever damages has already
happened cannot be reversedunfortunately. However if it gets worse means in advances
stages of this condition we can treat it in many ways like Laser treatment where we pass
laser to the back of the eye that is retina and burn the new blood vessels which are formed
there and also seal the leaking blood vessels. This will reduce it getting worse. Sometimes
we may have to inject some type medications {( anti-VEGF - ranibizumab (Lucentis) and
aflibercept (Eylea)}to the back of the eye to prevent new blood vessels forming there. Very
rarely we may do some surgery (Vitreoretinal surgery ) to remove some of the vitreous
humour from the eye. This is the transparent, jelly-like substance that fills the space behind
the lens of the eye.
Pt: Ok doctor.
Dr: Any other questions ?
Pt: If I do everything what you suggested, will I not lose my vision doctor ?
Dr: Mr.. If you do everything what I suggested the chances of you losing vision will be
greatly be reduced. So, I sincerely suggest you to follow everything we discussed.
Pt: Ok doctor.
Dr: Any otherquestions?
Skin lesion
25 year female presented with swelling on shoulder. Take relevant history and
talk to her about the management. Take informed consent for surgery. There is
Pt- it looks ugly. I am getting married soon. It will be visible when I wear my
Dr-anypain? Pt-No.
Dr: Have you noticed any swelling in the arm pit or in the neck ( spread to lymph
node in melanoma) ? Pt : No
Pt – it is covered with my dress but for wedding I will be wearing a dress below my
Dr: Have gone on holidays and exposed your skin to sun ? Pt: Yes/No
Dr: Have you used sun beds for skin tanning? Pt: Yes/No
Dr – Any of your family members had any such problems ( family history is ahigh
different candidates]
Dr- It looks like a growth in the skin. It looks more like a non cancerous type of
I also need to examine your neck and armpit for any swellings ( lymphadenopathy).
Dr – This type of growth does not need to be removed for medical reasons.
Dr:.Most of the time it can remain like that for the whole life without causing any
problem. However if it is mole it can rarely turn into cancerous type what we
So you need to keep an eye on that to watch for any changes like changes in size,
colour, border, surface or discharge or bleeding – then you need to come back to the
hospital.
Pt:Ok
Treatment options:
Dr: We have several treatment options. We can surgically remove it under local
anaesthesia. (We just make the area numb by giving anaesthetic injection to the site).
We have other options like what we call as shave removal with a blade.
Other ways to remove it is by freezing with liquid nitrogen. This is like a spray. It
does not require any anaesthesia. The swelling will fall off after few days.
It can also be removed by Laser. This treatment uses intense bursts of light radiation
to break down the abnormal cells in the skin. This method usually takes two or three
treatments to remove the swelling completely.
Some people do it on their own. But it is better if we do that to make sure everything
is fine.
Pt – how long istheprocedure? Dr- 10 –
Dr– We have expert doctors to do the operation. There will be small thin scar may not
be noticeable.
Dr- Unfortunately sometimes they can come back. Any other concerns ?
Dr: Are you happy to go ahead with the procedure ? Pt: Yes.
Dr- OK. I will talk to my seniors and we will arrange further tests and the date for the
You can go out in the sun; however, it is advised to wear proper sun protection like
hats, protective clothing, sun creams to prevent moles from forming in the future and
If it all you develop any swellings like this please come to us immediately.
A AACG(acute angle closure Glaucoma) Pain worse in dark, haloes around light,
DH
Dr: Hello Mrs... My name is Dr... one of the junior doctors in the Emergency Department.
P: Hello doctor
Dr: What brings you into the hospital today?
P: I have this pain in my left eye doctor
Dr: Once again I am very sorry Mrs... Could you tell me when it started?
P: It started suddenly around 2-3 hours ago
Dr: Do you have pain anywhere else ? P: I do have pain on my left side forehead as well.
Dr: Any redness of your eye?
P: Yes doctor (She might show you the picture of the red eye)
Dr: Any watering from your eye? P: No
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Dr: Have you noticed any coloured halos when you look at a light source?
P: No
Dr: Do you have any problem with your vision?
P: My left eye feels a little blurred.
Dr: I'm sorry to hear that Mrs... when did that start?
P: Same time this morning doctor.
Dr: Do you have any discharge in the eye ( conjunctivitis) ? P: No
Dr: Do you have any itching in the eye ( allergy) ? P- No
Examination
I would like to examine your eye Mrs... (Patient might show a picture of a red eye)
Diagnosis:
Dr: Mrs... With the information that you have given me and after the examination, it
seems you have a condition called Glaucoma. Do you know whatthatis? P:No
Dr: In the eye there are two compartments filled with fluid... Sometimes when there is an
increase in the production of fluid or a blockage in the outflow, the pressure inside the eye
can increase and that is what causes the pain and the redness in the eye.
P: (she might get upset_ console as needed) Oh.. It’s my fault then?
Dr: No Mrs.... it's not your fault.. It is an expected side effect of the medication and though
not everyone on the drug develops the S/E, some people might. Firstly, we have to stop this
medication. We will give some other medication for your depression.
Investigation
Dr: We will have to run some tests to confirm the diagnosis. We will do a test called
tonometry to check the pressure inside your eye.
Treatment:
We will also have to start you on treatment immediately to prevent loss of vision. We have
a number of options.
We will give you some eye drops called Pilocarpine to reduce the pressure.
We also have drops called Timololwhich will also help remove the excess fluid inside your
eye.
We can also give you some medication called Acetazolamide into your vein to do that.
We will refer you immediately to the Ophthalmologist for the further treatment.
Are you following me Mrs...?
Epilepsy
Dr: Hello Mr Sandeep Singh, I a Dr… one of the junior doctor in themedical
department. How areyou doing? Pt: I am OKdoctor.
Dr: I understand you were diagnosed to have epilepsy. I am sorry about it. Howis
your conditionnow? Pt: Doctor I had fits again afterthat.
Dr: I am sorry to hear about it. When exactly was that ?
Pt: Once few days ago and once about a week ago when I was in the party. Why did
that happen doctor ?
Dr: There could be many reasons why people still have fits even after treatment.Can
I ask you few questions to see why this would have happenedtoyou?
Pt:Yesdoctor.
Dr: Have been given medications forthat?
Dr: You need to be careful when you have fits. Avoid going near the fire.
Who cooks food for you ?
Pt: I live with few other friends. I cook food.
Dr: May be your friends cook food for you and you can do some other work for them.
Also avoid using gas cookers. Electric cookers are better. When transferring the food
to plate please take the plate to the pan and not hot pan to the plate.
You should be careful when taking shower. Do not take bath in bath tub instead take a
shower.
Pt: OK
[ sodium valproate does not affect the combined pills - so she can continue.
Carbamazepine reduces the effects of combined pill so they should increase the dose
9double the dose) of oestrogen in the combined pill and also use other forms of
contraception.]
Perform a CT head scan within 1 hour of the risk factor being identified:
GCS less than 15 at 2 hours after the injury on assessment in the emergency department.
Any sign of basal skull fracture (haemotympanum, 'panda' eyes, cerebrospinal fluid
leakage from the ear or nose, Battle's sign).
Post-traumatic seizure.
For adults with any of the following risk factors who have experienced some loss of
consciousness or amnesia since the injury, perform a CT head scan within 8 hours of
the head injury:
• More than 30 minutes' retrograde amnesia of events immediately before the headinjury.
Question
40 year old man Mr Andrew Robert collapsed outside a pub. Take history from the
patient and discuss the management with the patient.
Dr - What brings you to the hospital ? Pt - Doctor I passed out
Dr -When Pt - I just came out of the
restaurant and passed out
Dr – Was there any one with you ? Pt - yes my wife was with me.
Dr - How did this happen - Pt: We are in the restaurant, we
came out and suddenly I
passedout.
Dr: Did you slipped or tripped ? Pt: I am not sure. ( sometimes
he may say I tripped on the
pavement)
Dr - How long did you lose consciousness Pt – I am not sure because
when I was awake I was in the
ambulance.
Dr - Did you recover completely after this, or was there Pt – yes, I did recover
any drowsiness completely immediately after
the incident
Dr - Any head injuries when fell down ? Pt – No/Yes
Dr: Did you had any head injury before you lost Pt:No
consciousness ?
Dr - Any headache … Pt - no
Dr: Did you vomit after this ? Pt: Yes twice
Dr – Did anyone tell you that were jerking ( fit) at that Pt - no
time ?
Did you wet your pants do you know ? Pt - no
Dr: Do you know whether you had any bleeding from ear Pt - no
nose ?
Dr: How much do you remember before this incident ? Pt: Sometimes he may say I
( any amnesia for 30 min beforeincident) remember everything until I
just passed out / sometimes he
may say I just remember going
into the restaurant and then my
wife told me that when we
came out I just passed out.
Dr: How much do you remember before this incident ? Pt. I remember when I was
awake I was in the ambulance
and remember everything after
that.
Dr - Is this the first time …. Pt-Yes
Dr -Any medical problems like – DM, HTN, Heart Pt – No
conditions, Epilepsy, Stroke
Dr -Did you drink alcohol just before this Pt – Yes doctor but it is same
type and same amount as usual
Dr -Did you use any recreational drugs just before that Pt - No doctor.
happened …
Dr – Do you take any medications ? Pt – No ( Any drug Overdose)
Any blood thinners ?
Dr – Any of your blood relatives have any medical Pt - No
conditions like DM, Heart conditions or epilepsy ?
Dr - Do you live with any one ? Pt – Yes, my wife
Dr: Mr Robert, I need to examine you ( Examiner may not give any findings).
With what you told me I think you have injured your head and probably you have some
bleeding inside your head. We need to admit you in the hospital and do CT scan of the
head to check whether you have the bleeding. Is that OK?
Pt: No Doctor I am fine now. I want to go home.
Dr:MrRobertwiththesymptomswhatyouaretellingmelikethatyouhaveheadacheand
vomiting, these are the signs of bleeding inside the head. It will be very dangerous for you
togohome.Weneedtoadmityoutreat youifyouhavebleedinginsideyourhead.Wemay
needtodooperationonyourheadtoremovethebloodclotifatallyouhavethebleeding
inthebrain.Wewillalsodosometeststoseewhydidyoufall–likewewilldoECG(heart tracing,
check your bloodsugar).
However if all these tests are normal then you can go home. Is that OK ? If we discharge
you then you should stay at home at least for 24 hours and your wife should take care of
you. If you have any symptoms like ( warning signs) continued headache, continuously
vomiting, Drowsiness or fits you should come back.
Pt: Ok doctor. Thank you very much.
Hypertension – Losartan
Question: Mr Pat Brown 50 year old man was admitted to the hospital 4 weeks ago for
cellulitis and was noted to have high blood pressure and treated for HTN with
medications. He was discharged 2 weeks ago and he has come back for follow up of
blood pressure.
He also has diet controlled diabetes.
Dr: OK let me check the book and let you know. Check the BNF
It is Enalapril medication is giving you cough. One of the side effect of this medication is
cough.
Mr Parker it is very important to take this medication to control your blood pressure. Do
you think you can continue taking this medication. You may get used this cough after some
time.
Dr: No doctor I don’t want this medication. It is causing me too much problem.
Dr: OK don’t worry. We have some other medication to treat what we call Losartan
( Angiotensin receptor blocker – ARB). That will help to control your high blood pressure
as well as it is good for the kidneys also. However if you have any problems in your heart
or liver this medication may not be good. Do you have any problem in the heart or liver
?Dr: No doctor
Dr: Ok then this should be good for you.
Pt: How do I take it ?
Dr: It can be taken by moth with or without food. Dose will be 50mg once a day but then
we will adjust the dose according to your blood pressure.
Pt: Will there be any side effects for that.
Dr: Unfortunately one of the side effects of this medication is also cough but it is not as
much as Enalapril. Very rarely it can cause allergic reaction – in that case you should
stop it. It can also cause body pain – please tell your GP if that happens.
Dr: It is very important to take medications regularly. You should not stop taking
medications on your own without talking to your doctor. If you do not take medications
regularly your blood pressure can shoot up and it can cause other serious problems.
Dr: Anyotherconcerns Pt:No
Dr: Mr Parker – Do you want to know about your other medications ?
Pt: No doctor
[ If he says he wants to know then talk about them -ASPIRIN:- This is a blood thinner
tablet. It reduces the risk of clots forming in your blood. This reduces your risk of having a
stroke or heart attack.
31
Dose as mentioned in the prescription. ( 75 mg one tablet, Once a day, by mouth, after
food) SE - Can cause tummy irritation, slight bleeding in stomach and youmaynotice
dark stool if it happens please inform yourGP.
Dr: Mr Parker it is very important that you should keep your blood pressure under control.
Otherwise it can cause serious health problems like heart problems and even stroke.
Dr: Do you do exercise ? Pt : No
Dr: You should go for regular exercise – jogging or at least brisk walk for 30 min at least
every day for about 5 days a week. This helps to keep the blood pressure under control.
Dr: How is your diet ?
Pt: I eat fast food/ healthy food .
Dr: You should eat less of foods which contains high fat like red meat. Instead you cna eat
chicken and fish. You should also eat more of fruits and vegetables.
Pt: Ok
Dr: Since you have diabetes it is important to keep the sugar also under control otherwise
high blood pressure and diabetes combined together can cause serious health problems.
Heamaturia
Red flag symptoms
• Painless macroscopichaematuria
• Symptomatic microscopic haematuria in absence ofUTI
• Age >50years
• Abdominal mass on examination
History andexamination
Patients presenting with haematuria should be asked about symptoms of one of the most
likely causes, a UTI. Symptoms of frequency, urgency and dysuria point to this diagnosis.
Haematuria presenting with abdominal pain 'from loin to groin' is classical of renal calculi,
and there may be a previous history of similar episodes.
On the other hand, haematuria presenting without pain raises the possibility of a bladder or
renal malignancy and should prompt urgent referral.
In the absence of a UTI, microscopic haematuria associated with systemic symptoms, such
as joint pains, a rash or fever, should lead you to suspect an inflammatory cause, such as
systemic lupus erythematosus or Henoch-Schonlein purpura.
Consider post-infectious glomerulonephritis or IgA nephropathy if there is a history of
infection. A thorough drug history will reveal any nephrotoxic medications, such as
cyclophosphamide or NSAIDs. Note that warfarin is not in itself a cause of haematuria.
Remember to ask about recent travel (schistosomiasis) and occupational exposure (bladder
malignancy).
Examination of BP (renal disease) and abdomen (urological malignancy) are vital. Genital
examination is often unhelpful although examination of the prostate is necessary if there
are symptoms of prostatism. Examine the skin and joints for signs of systemic disease.
Investigations
Dipstick examination will rule out other causes of red urine and may show associated
proteinuria, which hints at a renal cause.
An MSU should be sent for microscopy culture and sensitivity testing, and a urinary
protein-creatinine or albumin-creatinine ratio obtained.
Bloods including FBC, U&Es and clotting will establish the amount of blood loss, renal
function and any coagulopathy.
Imaging may be required to investigate calculi, and a renal ultrasound may be performed.
Any patient with frank and painless haematuria requires urgent specialist investigation,
which will involve a cystoscopy and/or a CT urogram.
Causes of haematuria
1) Kidney 4) Prostate
Urethral trauma
Ureteric stones Urethral stones
Neoplasm Neoplasm
Trauma
3) Bladder General causes
Hemoglobinuria
Myoglobinuria
Beetroot
Senna
Rifampicin
Phenopthalein
Exam question
You are the FY2 doctor in the Urology department.
Middle age man presented to the hospital with the history of passing blood in the
urine.
Take relevant history and discuss the further management with the patient.
Dr: Hello Mr … I am Dr…. One of the junior doctor in the urology department.
How can I help you ?
Pt: Doctor I am passing blood in the urine.
Dr: Can you tell me anything more aboutit? Pt: Likewhat?
Dr: Since when did you noticethis? Pt: Since last fewdays.
Dr: Is the bleeding at the beginning of urinating ( urethra or prostate) or at the end of
urinating ( bladder or prostate) or throughout ( bladder, kidney ureter) ?
Pt: It is throughout.
Dr: Do you have any pain while passing urine (UTI)? Pt:No
Dr: Do you have fever (UTI)? Pt:No Dr : Increased frequency orurination?
7
Pt : No/ Yes
Dr: When you pass urine does it flow properly or does it dribble ( Prostate
symptoms) ? Pt : No/ Yes there is dribbling.
Dr: Do you have to run to the loo when you get the sensation of passing urine
(prostatism) Pt : Yes/ No
Dr: Did you have any injury to the penis or totummy?
Pt:NoDr : Did you ever had any kidney stones before ? Pt :No
Dr: Did you have any kidney problems before (polycystickidney) ?
Pt:NoDr: Any pain going from loin to groin at all ( ureteric stone)? Pt :No
Dr: Any pain in your loin area ( renalcancer)?
Pt:NoDr:
Any mass in the loin area (renalcancer)? Pt:NoDr:
Have you noticed any change in your weightCancer)? PT:
No / Yes ( how much in how much time?)
Dr : Do you cough ( TB) ? Pt:No Dr: Night sweats ( TB) ?
Pt:NoDr: Do you smoke ? Pt : Yes ( How many and how long ?)
Dr : Have done any strenuous exercise recently ? Pt : No
Dr: Do you have any pain at the back ( secondary in the vertebra – primary in the kidney
or prostate) ? Pt : No
Dr: Any procedures or operations done recently on kidney, urine bladder or urethra
( front passage) ? Pt : No
Dr: Do you have any bleedingdisorders?
Examination:
Mr… I need to examine your tummy and back passage to check the prostate gland.
[ Examiner may say prostate is enlarged and smooth and no other abnormal findings ]
8
Diagnosis :
Mr… While examining I found that your prostate gland ( a gland which is present at the
base of the urine bladder) is enlarged.
However Mr .. There is a possibility that you may be having some growth in the urine
bladder causing this problem. We need to do further tests to find out what exactly is
causing the bleeding from the urethra. ( If you are the FY 2 doctor in the Urology mention
talking to seniors about the further investigations and treatment, if you not in the Urology
department – then mention referral to Urologists specialists in Kidney and urine excreting
organs for further investigations and treatment).
Investigations:
Mr… We will have to test your urine first to check for the blood or other things (protein)
which may show any problem in the kidney. We need to do investigations like cystoscopy
to check inside the urine bladder. In this procedure we pass a tube with the camera attached
to that through the urethra ( front passage ) into the urine bladder and we have a look inside
the bladder and take any tissue samples if there is any growth there and test that in the lab.
Also we may need to test the prostate gland to see what type of growth it is whether it is
cancerous or non - cancerous. We will have to do ultrasound scan and do some blood test
specific for the prostate gland.
Also we need to do CT scan of the lower tummy area to check whether the cancer has
spread if at all it is cancer. Do you follow me?
Pt : Yes doctor
Treatment:
Dr: Depending on the test result we will treat you. If at it is bladder cancer, depending on
whether it is spread or not we will treat either by doing surgery – if possible we may
remove just the growth or we may need to remove the whole urine bladder and create an
artificial urine bladder.
We may also need to treat with chemotherapy and radiotherapy.
If at all it is cancer of the prostate - again depending on the result we will treat either by
surgery or chemotherapy or radiotherapy.
Are you following me? Is that OK?
Pt : Ok doctor. Thank you very much.
9
TIA
10
11
69 year old lady had presented to A&E with sudden onset facial weakness, unilateral limb
weakness and slurring of speech.
On evaluation, found to have BP of 150/90.
Neurological examination was completely normal. She is worried and has given consent to
talk to her husband.
Talk to him, take history, discuss management and address concerns.
Dr: Hello Mr.... my name is Dr... Are you Mrs. X's husband?
H: Yes doctor..
Dr: How are you doing Mr...?
H: I'm fine doctor.. I was told someone would come by to talk to me about my wife.
Dr: That's correct Mr... I am here to talk to you about your wife. Could you please tell me what
exactly happened?
H: We were at home. She was just sitting and watching TV. And all of a sudden she wasn't able to
articulate words. I noticed some change in the right side of her face and she couldn't move her right
arm as well. So I just called an ambulance within 15 minutes they arrived her and brought her to the
hospital. But after we got here, within an hour, she was perfectly fine! ( sometimes he may say
symptoms lasted 2 hours)
Dr: Ok Mr... You did the right thing. It's very good that you called for an ambulance immediately
and brought her here. I do have a few more questions to ask you about your wife's condition prior
to this incident. Would that be all right? H: Yes
Dr: Ok.. Now Mr... I have a few questions about your wife's lifestyle.
What is her diet generally like?
H: She eats a healthy balanced diet doctor. Plenty of fruits and vegetables.
12
Dr: Ok. That is very good Mr... Does she get exercise?
H: A little.. Yes.. Moving around the house.. Gardening etc.... ( sometimes he may say we go for
brisk walking every day – so does good exercises)
Dr: Does she smoke? H: No
Dr: Does she consume alcohol? H: No
Dr: Mr... as you had mentioned, your wife's symptoms resolved within an hour.. And on
examination, she had no neurological problems. From the information we have gathered, it appears
that she has had what we call a Transient Ischemic Attack (TIA) or a mini-stroke. Do you have any
idea what that is? H: No
Dr: A TIA is a medical condition where there is a momentary decrease or loss in blood supply to
the brain. This could either be because of some narrowing of the blood vessels in the neck that
supply blood to the brain... or because of some rhythm problems in the heart. Are you following me
Mr...?
H: Yes doctor.. Is it serious?
Dr: Mr... A TIA as such is not serious as it usually resolves by itself within 24 hours. But we need
to evaluate and find out why it happened because if it happens again, it might not be a TIA, but
something more serious, like a complete stroke. Do you follow me?
H: Yes doctor. What are the chances that she may get stroke doctor ?
Dr: Unfortunately the risk of she getting the stroke in the next few days itself is very high.
We need to admit her and treat her immediately to reduce the chance of she getting the stroke in
the next few days.
Investigations
Dr: We need run some tests... to find out why this happened.
H: What kind of tests doctor?
Dr: First we will have to do a CT scan of her head... to make sure that there is no evidence of a
stroke. We will then do an ECG or a heart tracing to look for any rhythm problems. We will also
do some blood tests to check her sugar and cholesterol levels.
Additionally, we will have to do a scan called a Doppler... of the blood vessels of her neck to see
if they are narrowed. Are you with me Mr...? H: Yes
13
Treatment:
Dr: Mr... on examination, we also found that your wife's BP was on the higher side. It was 150/90.
We will have to start her on a medication to control her BP. We will also start her on Aspirin,
which can help prevent such attacks in the future. We will also ask the Neurologist to evaluate
your wife. Do you have any questions for me Mr...?
Warning signs :
If you do take her home Mr... I would like to inform you about the warning signs of a stroke
[FAST – Facial weakness, Arm weakness, Speech problem – Time to call the ambulance]. If
you ever notice any weakness in her face or limbs... or any slurring of her speech, please call an
ambulance and bring her to the hospital immediately as the next time, it can be even stroke. Do
you have any questions for me ?
H: No doctor.. Thank you.
Dr: Hello Mr. Zimmerman... I am Dr.... one of the junior doctors here in the GP
clinic..
Pt: Hello doctor.. Very nice to meet you.
Dr: Nice to meet you too Mr. Zimmerman. I understand you made an appointment
with the clinic because you had some concerns. Is that correct?
Pt: Yes doctor. I'm very worried that I might develop stroke.
Dr: Could you please tell me why you are worried about it?
Pt: I had a health check by the Occupational health department 2 years ago and they
told me that my blood pressure is bit high at that time. But I was too busy and I
didn’t bother much about it. But now I am very worried it.
Dr: Can you please tell me why are you worried of getting stroke if your blood
pressure is high ?
Pt: My father and elder brother had high blood pressure. My father died of stroke
many years ago and my brother had stroke few years ago. He has just recovered
now.
Dr: I am very sorry to hear that Mr. Zimmerman. But don’t worry Mr Zimmerman
we can help you to reduce any risk of you getting stroke.
Mr Zimmerman, do you know what is stroke and why people get this condition ?
Pt: I know people can have paralysis if they have stroke.
Dr: That is right Mr Zimmerman. This condition happens either because there is
bleeding in the brain and blockage to the blood supply to the brain. People who
have this condition can have paralysis. Sometimes people do improve from this
problem but sometimes the paralysis can last forever. Sometimes this condition can
be even life threatening.
Pt: I see.
Dr: Sometimes this condition can run in the family because of genetic reasons.
However, there are lot of others risk factors why people get stroke. We may be able
to reduce the chances of you getting stroke if you have any other risk factors and if
we can modify those factors. I am really glad that you came to the hospital now. Let
us see if you have any other risk factors and try to sort out those. Is that OK Mr
Zimmerman?
Pt: Ok Doctor.
Dr: Did you have any strokes or mini strokes previously ? Pt: No
Dr: Do you have any heartproblems? Pt :No
Dr: Do you have any palpitations ( Atrial fibrillation) ? Pt : No
Dr: Do youhavediabetes? Pt:No
Dr: You said your blood pressure was high before. Our nurse checked your blood
pressure now which is 160/90 which is quite high. High blood pressure is one of the
major risk factor which can cause rupture of the blood vessels in the brain and cause
bleeding in the brain. It is very important to keep the blood pressure under control.
We can give medications to keep the blood pressure under control. I will talk to my
seniors about it and get back to you.
However, apart from medications you may need to do lot of other things to keep the
blood pressure under control.
Pt: What is that doctor ?
Dr: One important factor is diet. Can I ask you what type of food do you eat
usually?
Pt: You know doctor. I am a NHS manager. I'm usually busy. I don’t have time to
cook food. So I eat out most of the time. I have to eat fast food - I eat chips, burger,
steaksetc
Dr: Mr Zimmerman, the kind of food what you are eating is not good because they
have very high bad fat content that is cholesterol. This can increase the blood
pressure and contribute to stroke. I sincerely advise you to eat more of white meat
which has less bad fat like chicken and fish. I also advise you to include plenty of
fruits and vegetables also in your diet. Also please reduce the salt content in your
food because it can increase the blood pressure. I will refer you to a dietician who
will advise you in detail about the healthy diet. Is that OK ?
Pt: That is fine. Doctor.
Dr: That is good. Can I ask do you do exercise ?
Pt: Not much doctor. As I said I don’t get time to do exercise.
Dr: I understand you are very busy. However, I sincerely advise you to do some
exercise like walking for about 30 min every day at least 5 days a week. If that is
not possible may be you can have a treadmill at home and exercise on that while
you are watching TV. Exercising regularly will keep you healthy and also helps to
keep the blood pressure under control. What do you say ?
Pt: Yes doctor that seems to be a good idea.
Dr: Excellent. Do you smoke Mr Zimmerman?
Pt: Yes doctor I smoke about 10 to 15 cigarettes a day for the last 15 to 20 years
doctor.
Dr: Again smoking is not good for health at all as you may know. Smoking also can
increase the blood pressure and also can cause lot of other health problems. I
strongly advise you to stop smoking. We can help you to stop smoking if you wish.
Do like to consider that Mr Zimmerman.
Pt: Doctor you know my work is very stressful. In fact NHS is going through lot of
financial crisis. I have to do lot of work to prevent this financial problems. I might
even lose my job. I have to smoke to relieve my stress doctor.
Dr: I can surely understand your problem. However, there are many other ways to
relieve stress. May be you can take some break from work and go for relaxation
classes and yoga classes which might help you to relieve from stress. Remember
stress also can increase the blood pressure. What do you say?
Pt: Yes doctor you are right. I will try my best to do that.
Dr: Do you drink alcohol Mr Zimmerman?
Pt: Yes doctor. I drink about 2 glasses of wine every day and also whisky
sometimes over the weekends.
Dr: Mr Zimmerman, alcohol also is not good for the health. I sincerely advise you
to cut down drinking alcohol and drink within the recommended limits that is not
more than 14 units per week. We can help you to cut down if you wish. What do
you think ?
PT: Yes doctor I will surely think of that.
Dr: Excellent. Do you have any questions?
Pt: Doctor if I follow all the advices what you gave then will I not get stroke?
Dr: Mr Zimmerman. There is something called as modifiable and non- modifiable
risk factors for stroke. Non modifiable factors are like age above 60 years, genetic
cause means inherited risk which we can’t do anything about these. However there
are lot other modifiable risk factors like all the factors what we discussed so far like
diet, exercise, smoking which you can modify and have a healthy life style. This can
substantially reduce the risk of you getting stroke. Also there are other risk factors
like abnormal heart rhythms and narrowing of the blood vessels in the neck which
supplies blood to the brain. We can check whether you have any problems like these
and we can treat them if you have. All these things will greatly reduce the risk of
getting stroke.
Ureteric calculus
Risk factors
Several risk factors are recognised to increase the potential of a susceptible individual to develop
stones. These include:
Anatomical anomalies in the kidneys and/or urinary tract - eg, horseshoe kidney, ureteral
stricture.
Family history of renal stones.
Hypertension.
Gout.
Hyperparathyroidism.
Immobilisation.
Relative dehydration.
Metabolic disorders which increase excretion of solutes - eg, chronic metabolic acidosis,
hypercalciuria, hyperuricosuria.
Deficiency of citrate in the urine.
Cystinuria (an autosomal-recessive aminoaciduria).
Drugs - eg, diuretics such as triamterene and calcium/vitamin D supplements.
More common occurrence in hot climates.
Increased risk of stones in higher socio-economic groups.
Contamination - as demonstrated by a spate of melamine-contaminated infant milk formula.
Fever.
Solitary kidney.
Known non-functioning kidney.
Inadequate pain relief or persistent pain.
Inability to take adequate fluids due to nausea and vomiting.
Anuria.
Pregnancy.
Poor social support.
Inability to arrange urgent outpatient department follow-up.
People over the age of 60 years should be admitted if there are concerns on clinical condition or
diagnostic certainty (a leaking aortic aneurysm may present with identical symptoms).
All patients managed at home should drink a lot of fluids and, if possible, void urine into a container
or through a tea strainer or gauze to catch any identifiable calculus.
Analgesia: paracetamol is safe and effective for mild-to-moderate pain; codeine can be added if more
pain relief is required. Paracetamol and codeine should be prescribed separately so they can be
individually titrated.
Patients managed at home should be offered fast-track investigation initiated by the hospital on
receipt of a letter or email completed by the general practitioner.
Patients should ideally receive an appointment for radiology within seven days of the onset of
symptoms.
An urgent urology outpatient appointment should be arranged for within one week if renal imaging
shows a problem requiring intervention.
Surgical
Approximately 1 in 5 stones will not pass spontaneously and will require some form of intervention.
If the ureter is blocked or could potentially become blocked (eg, when a larger stone will fragment
following other forms of therapy), a JJ stent is usually inserted using a cystoscope. It is a thin hollow
tube with both ends coiled (pigtail). It is also used as a temporary holding measure, as it prevents the
ureter from contracting and thus reduces pain, buying time until a more definitive measure can be
undertaken.
Procedures to remove stones include:
Extracorporeal shock wave lithotripsy (ESWL) - shock waves are directed over the stone to
break it apart. The stone particles will then pass spontaneously.
Percutaneous nephrolithotomy (PCNL) - used for large stones (>2 cm), staghorn calculi and
also cystine stones. Stones are removed at the time of the procedure using a nephroscope.
Ureteroscopy - this involves the use of laser to break up the stone and has an excellent
success rate in experienced hands.
Open surgery - rarely necessary and usually reserved for complicated cases or for those in
whom all the above have failed - eg, multiple stones.
Several options are available for the treatment of bladder stones. The percutaneous approach has
lower morbidity, with similar results to transurethral surgery while ESWL has the lowest rate of
elimination of bladder stones and is reserved for patients at high surgical risk.[7]
Complications
Complete blockage of the urinary flow from a kidney decreases glomerular filtration rate (GFR)
and, if it persists for more than 48 hours, may cause irreversible renal damage.
If ureteric stones cause symptoms after four weeks, there is a 20% risk of complications, including
deterioration of renal function, sepsis and ureteric stricture.
Infection can be life-threatening.
Persisting obstruction predisposes to pyelonephritis.
Prognosis
Most symptomatic renal stones are small (less than 5 mm in diameter) and pass spontaneously.
Stones less than 5 mm in diameter pass spontaneously in up to 80% of people.
Stones between 5 mm and 10 mm in diameter pass spontaneously in about 50% of people.
Stones larger than 1 cm in diameter usually require intervention (urgent intervention is required if
complete obstruction or infection is present).
Two thirds of stones that pass spontaneously will do so within four weeks of onset of symptoms.
A stone that has not passed within 1-2 months is unlikely to pass spontaneously.
The following features predispose to recurrent stone formation:
First attack before 25 years of age.
Single functioning kidney.
A disease that predisposes to stone formation.
Abnormalities of the renal tract.
Prevention
Recurrence of renal stones is common and therefore patients who have had a renal stone should be advised to
adapt and adopt several lifestyle measures which will help to prevent or delay recurrence:
Increase fluid intake to maintain urine output at 2-3 litres per day.
Reduce salt intake.
Reduce the amount of meat and animal protein eaten.
Reduce oxalate intake (foods rich in oxalate include chocolate, rhubarb, nuts) and urate-rich foods
(eg, offal and certain fish).
Drink regular cranberry juice: increases citrate excretion and reduces oxalate and phosphate
excretion.
Maintain calcium intake at normal levels (lowering intake increases excretion of calcium oxalate).
Depending on the composition of the stone, medication to prevent further stone formation is sometimes
given - eg, thiazide diuretics (for calcium stones), allopurinol (for uric acid stones) and calcium citrate (for
oxalate stones).
Question :45 year old man presented to the hospital with abdominal pain.
Take history and discuss the management with the patient.
Any vomiting ? Are you able to drink? Are you able to pass urine?
I need to examine your tummy. (No response from the examiner)
Diagnosis
Mr… I think you have a stone in the ureter. Ureter is a tube which drains urine from the kidney to
the urine bladder.
Investigations: We need to do some tests like CT scan of your tummy area to confirm that. Also
we need to test your urine to check whether it shows any blood and any infection
markers( examiner says – urine test shows blood). We need the check your blood to check how
your kidneys are functioning and also check some chemicals like for calcium, phosphate and
other things.
Treatment: If the tests confirm that it is stone we treat it. We have various options to treat it.
Sometimes this stone will pass out on its own if it is very small.
We will give you very good pain killer medication what we call as Diclofenac as a suppository
through your back passage.
If your pain is relieved and you are able to eat and drink and able to pass urine then you can go
home. Drink plenty of water and the stone may pass out on its own. If possible, you should pass
urine into a container or through a tea strainer or gauze to catch any identifiable calculus.We will
give you an appointment for follow up within a week.
However, if your pain is not relieved and if you keep vomiting continuously or if the scan shows
some abnormality in the kidney then we will keep you in the hospital and treat you.
We can give you some fluids through your veins or medications( tamsulosin or nifedipine) which
will help to flush out the stone in the urine.
If that does not work then we have something what we call as shock wave treatment where break
the stone into smaller pieces by giving some type of shock and then it will flush out easily.
If these things do not work then either we can do a key hole surgery and remove it or rarely we
may have to do open operation to remove it.
If we get the stone we will send it to the lab for further analysis. Depending on the composition of
the stone we may givemedication to prevent further stone formation. [ eg, thiazide diuretics (for
calcium stones), allopurinol (for uric acid stones) and calcium citrate (for oxalate stones).
Reassure that the chances of child getting HIV infection is almost negligible because HIV bugs do
not survive outside human body. So usually we do not do any tests for HIV and we do not offer any
medications to prevent them getting HIV infection.
Hep B – there are slight chances of child getting hep B infection if the child is not vaccinated.
We will check from the GP whether the child had Hep B vaccine or not and if the child did not had
Hep B vaccine we will give Hep B vaccine and another medication called Hep B immunoglobulin
to prevent child getting Hep B infection.
Nanny may be taking down notes – ask her why – she may say I need to tell child’s parents
everything you say now. – appreciate. Tell her to bring the parents later so that you can explain
everything to them directly.
Warning signs – if the child develops redness, swelling discharge from the wound site – this is sign
of wound infection – you need to bring the child back.
Any other concerns.
Injury from used needles and syringes found in community settings arouses much concern,
especially when children find discarded needles and injure themselves while playing with them.
The user is generally unknown, and parents and health care providers fear that the needle may have
been discarded by an injection drug user. Although the actual risk of infection from such an injury
is very low, the perception of risk by parents results in much anxiety. Evaluation and counselling
are needed.
The important pathogens to be considered in this situation are hepatitis B virus (HBV), hepatitis C
virus (HCV) and HIV. It is essential that the health care provider be knowledgeable about the risks
of acquisition of these viruses following needle stick injuries, and the recommendations for
management and follow-up. In the absence of up-to-date local data, it is prudent to assume that the
needle may have been contaminated with one or more of these viruses.
There have been single case reports of HBV and HCV transmission and no reported transmission of
HIV following injuries by needles discarded in the community. A review of the literature up until
September 2007 yielded 12 case series from areas of high prevalence of blood-borne viruses. These
involved a total of 483 children with follow-up for HIV, 452 for HBV and 265 for HCV. There
were no infections. The majority of children received HBV prophylaxis, if it was indicated, but
only 130 children received antiretroviral prophylaxis.
Follow-up after any significant needle stick injury is essential. The clinician dealing with the initial
incident should ensure that the parents and child understand the importance of follow-up, and that
appropriate arrangements are made. Parents sometimes assume that if blood tests that are
performed at the time of injury are negative, then there is no possibility of infection and no need for
further testing.
Needle stick injuries may be prevented by educating children, parents, educators and health care
providers about the dangers of handling used needles, syringes and other objects contaminated with
blood. Children need to be made aware at an early age. In the studies of injuries from discarded
needles referred to above, the mean ages of the injured children were five to eight years. In one
study 15% of injuries occurred in children pretending to use drugs. There is a community
responsibility to provide adequate cleanup of parks and schoolyards. In addition, community
commitment is necessary to support addiction treatment and infection prevention programs for
injection drug users.
HBV
HBV is the most stable of the blood-borne viruses and can be transmitted by a minute amount of
blood. The risk of acquiring HBV from an occupational needle stick injury when the source is
hepatitis B surface antigen (HBsAg)-positive ranges from 2% to 40%, depending on the source’s
level of viremia. HBV can survive for up to one week under optimal conditions, and has been
detected in discarded needles. A case of HBV acquired from a discarded needle used by a known
HBV carrier has been reported.
Although HBV vaccine is now recommended for all children in Canada, most programs target
children who are older than the usual age at which they sustain accidental needle stick injuries.
Thus, the majority of injured children are likely to be susceptible to HBV infection. Postexposure
prophylaxis with anti-HBV immunoglobulin and HBV vaccine is effective if provided promptly.
HCV
The risk of acquiring HCV as a result of an occupational needle stick injury when the source was
infected varies from 3% to 10% . HCV is thought to be a fragile virus which would be unlikely to
survive in the environment, but there are little data at this time. There has been a case report of
HCV acquisition after an injury from a discarded needle.
Unfortunately, there is no effective postexposure prophylaxis at present. Alpha-interferon and
ribavirin are used in therapy of chronic HCV infection, but their benefit for prophylaxis is not
known. It is important to determine whether a potential exposure results in transmission of HCV
because 50% to 60% of infected children will have persistent, asymptomatic infection for which
follow-up by a specialist is indicated. Chronic hepatitis will eventually develop in some of these
cases, and antiviral treatment may be required.
HIV
The risk of acquisition of HIV from a hollow-bore needle with blood from a known HIV
seropositive source is between 0.2% and 0.5%, based on prospective studies of occupational needle
stick injuries. The risk is increased with higher viral inoculum, which is related to the amount of
blood introduced and the concentration of virus in that blood. The size of the needle, the depth of
penetration and whether blood was injected are also important considerations. In most reported
instances involving transmission of HIV, the needle stick injury occurred within seconds or
minutes after the needle was withdrawn from the source patient.
In contrast to the situation with health care workers, the source of blood in discarded needles is
usually unknown, injury does not occur immediately after needle use, the needle rarely contains
fresh blood, any virus present has been exposed to drying and environmental temperatures, and
injuries are usually superficial. HIV is a relatively fragile virus and is susceptible to drying.
However, survival of HIV for up to 42 days in syringes inoculated with the virus has been
demonstrated, with duration of survival dependant on ambient temperature. One study found no
traces of HIV proviral DNA in syringes discarded by intravenous drug users, while another study
found HIV DNA in visibly contaminated needles and syringes from shooting galleries.
It is extremely unlikely that HIV infection would occur following an injury from a needle discarded
in a public place. However, if the incident involved a needle and syringe with fresh blood, and if
some of the blood was injected, infection is theoretically possible and prophylaxis is indicated. In
occupational needle stick exposures, zidovudine prophylaxis was shown to reduce the risk of HIV
transmission from a positive source by 80% . Prophylaxis with combination antiretroviral therapy
is presumed to be even more effective. Whether two or three drugs should be used is controversial.
The use of three drugs is based on observations in treatment of HIV infection and the assumption
that maximum suppression will be most effective in preventing infection. On the other hand, two
drug regimens are better tolerated and adherence may be better with two than with three drugs.
:
Prevention
Parents, educators and health care providers should be made aware of the problem of
discarded needles.
Children should be educated about the potential dangers of injection drug use.
Children should be taught not to handle needles and syringes, and to report finding them to
an appropriate, responsible adult (parent, school teacher, police officer, etc), who should
then arrange for the safe disposal of the needle in a puncture-proof, closed container.
Community programs should be in place to keep parks and public places, where children
generally play, free of discarded needles.
Programs should be in place for the treatment and control of injection drug addiction, and
to adequately support HIV prevention, HBV vaccination and needle-exchange programs
for injection drug users.
Management
After the injury, the wound should be cleaned thoroughly with soap and water as soon as
possible. It should not be squeezed to induce bleeding.
The extent of the wound, if any, or the probability of exposure of open skin lesions or
mucous membranes to blood should be assessed.
The child’s immunization status for tetanus and HBV should be determined.
Tetanus vaccine, with or without tetanus immunoglobulin, should be given if indicated.
The circumstances of the injury should be documented (the date and time of injury or
exposure, where the needle was found, circumstances of the injury, type of needle, whether
there was a syringe attached, whether visible blood was present in or on the needle or
syringe, whether the injury caused bleeding and whether the previous user of the needle is
known).
Blood should be obtained from the child for:
Baseline HBV, HIV and HCV status (may be stored for later testing).
If antiretrovirals are being considered: complete blood count, differential, aspartate
aminotransferase, alanine aminotransferase, alkaline phosphatase, blood urea
nitrogen and creatinine.
Testing needles and syringes for viruses is not indicated. Results are likely to be negative,
but a negative result does not rule out possibility of infection.
If the user of the needle is known, attempts should be made to assess for risk factors for
blood-borne viruses and, if possible, to test for these viruses. Pending results, proceed as
for an unknown source.
Child has Test for anti-HBs antibody and HBsAg. If results are not available in 48 h:
not been
fully Give HBIG immediately (ideally within 48 h of injury; efficacy unknown
d against Give HBV vaccine (as soon as possible, and at latest within 7 days of
HBV injury).
Child has Test for anti-HBs antibody. If results are not available in 48 h, give dose of HBV
been fully vaccine.
vaccinate If anti-HBs antibody-positive, no further action required.
d against If anti-HBs antibody-negative, test for HBsAg:
HBV
If HBsAg-negative give HBIG and dose of HBV vaccine.
If HBsAg-positive, arrange appropriate follow-up.
ZDV + 3TC 13 years and >37 kg: One Tablet contains 300 mg
(Combivir) † tablet bid ZDV plus 150 mg 3TC
Protease inhibitor‡
*ZDV and 3TC are well tolerated. Occasionally children have anorexia, nausea,
vomiting, diarrhea, abdominal pain, fatigue and headache. Asymptomatic mild
neutropenia, anemia or elevation of liver enzymes may occur, which resolve after
treatment is completed;
‡
LPV/RTV may cause nausea, vomiting, diarrhea or abdominal discomfort;
§
Alternative dosing – <15 kg: (12 mg/kg LPV/3 mg/kg RTV)/dose twice a day
(bid); 15–40 kg: (10 mg/kg LPV/2.5 mg/kg RTV)/dose bid. tid Three times a day.
Centor criteria to aid diagnosis of Group A beta-haemolytic streptococcus
(GABHS)as a cause of presentation with a sore throat:
o tonsillar exudate
o tender anterior cervical lymph nodes
o absence of cough
o history of fever
presence of three or four of these clinical signs suggests that the
chance of the patient having GABHS is between 40% and 60%, so
the patient may benefit from antibiotic treatment
absence of three or four of the signs suggests that there is an 80%
chance that the patient doesn't have the infection, and antibiotics
are unlikely to be necessary
in patients with tonsillitis who are unwell, and have three out of four
of these criteria, the risk of quinsy is 1:60 compared with 1:400 in
those who are not unwell
centor criteria is not ideal, and will lead to some patients with
bacterial pharyngitis not being treated and result in unnecessary
antibiotic treatment for others
60 years old Mr.... was admitted with a chest pain a few days ago and was treated for Acute
Myocardial Infarction. Now, he is stable on medical therapy and is fit to be discharged. Your
consultant has commenced him on the medical therapy. Talk to the patient, assess him
clinically, and speak to him about lifestyle modifications.
Dr: Good morining, Mr... I am Dr .... One of the junior doctor in the cardiology dept. How are
you doing today? Pt: I am well doctor. I am going home today.
Dr: Congratualtions. My consultant has prescribed some medications. Do you have any
questions about them?Pt: No doctor, I know about the medicines.
Dr: Well that is fine. Could you please tell me how much do you know about your condition?
Dr: Well, Mr... there are certain risk factors which can lead to heart attacks. Some of them are
not modifiable while most of them are. And if we are able to control the modifiable risk factors,
we can maximally reduce the risk of getting heart attack. Are you understanding?
Dr: There are lot of others risk factors why people get heart attack. I would like to ask you a few
questions to know if you have any of those risk factors so that we can address them and help
you cope with this condition. We may be able to reduce the risk if we can modify those factors.
Pt: I see.
Dr: Do you have any heartproblems in the past? Pt : (No/Yes?)
Dr: Did you have any strokes or mini strokes previously ? Pt: (No/Yes?)
Dr: Do you have diabetes?Pt: (No/Yes?)
Dr: Do you have high levels of cholesterol in your blood?Pt: (No/yes?)
Dr: Cholesterol is involved in the formation of blood clot that can lead to blockade of artery
supplying the heart. Are you following?Pt: Yes doctor.
Dr: Do you have high blood pressure?Pt: (No/Yes?)
Dr: High blood pressure is one of the major risk factor which can cause lead to weakening of
heart muscle. It is very important to keep the blood pressure under control. However, as I have
told you apart from medications you may need to do lot of other things to keep the blood
pressure under control.Pt: What is that doctor?
Dr: One important factor is diet. Can I ask you what type of food do you eat usually?
Pt: You know doctor. I don’t know how to cook food. So, I eat out most of the time. I have to
eat fast food - I eat chips, burger, steaksetc
Dr: Mr, the kind of food what you are eating is not good because they have very high bad fat
content that is cholesterol. This can increase the blood pressure and contribute to heart attack.
I sincerely advise you to eat more of white meat which has less bad fat like chicken and fish. I
also advise you to include plenty of fruits and vegetables also in your diet. Also please reduce
the salt content in your food because it can increase the blood pressure. I will refer you to a
dietician who will advise you in detail about the healthy diet. Is that OK ?Pt: That is fine. Doctor.
Dr: I can understand. However, I sincerely advise you to do some exercise. However at least for
the first one month do minimal exercise like walking inside the house but later you can do some
exercise like brisk walking for about 30 min every day at least 5 days a week. Exercising
regularly will keep you healthy and also helps to keep the blood pressure and cholesterol under
control. What do you say ? Pt: Yes doctor that seems to be a good idea.
Pt: Doctor you know my life is very lonely. I am going through lot of financial crisis and I get
stressed some times.
Dr: I can surely understand your problem. However, there are many other ways to relieve
stress. May be you can take some relaxation classes and yoga classes which might help you to
relieve from stress. Remember stress also can increase the blood pressure. What do you say?
Pt: Yes doctor you are right. I will try my best to do that.
Dr: You should not drive for at least four weeks after a heart attack. Could someone help you
with that? Pt: (Yes doctor, my wife can drive?)
Dr: That is good. It is always sensible to contact the Driver and Vehicle Licensing Agency (DVLA)
to be sure. Also I would like to tell you something about air flight travels. You can usually fly as a
passenger within two to three weeks of a heart attack, as long as you have no complications.
This means that you have returned to your usual daily activities, your condition is stable and
you don't have any symptoms, or your symptoms are controlled. Are you following me?
Pt: Yes.
Dr: Regarding your sex life, I would like to recommend you that for a 3 to 4 weeks it is probably
best avoided. If you are able to walk without discomfort then a return to sexual relationships
should not cause any problems. If sex causes angina chest pains then tell your doctor. Pt: Yes.
Dr: You should have the annual influenza jab and be immunised against the pneumococcal
germ (bacterium). Okay? Pt: Yes.
Pt: Doctor if I follow all the advices what you gave then will I not get heart attack again?
Dr: As I have told you that there are both modifiable and non- modifiable risk factors for
developing heart attack. Non modifiable factors are like age above 60 years, genetic cause
means inherited risk which we can’t do anything about these. However there are lot other
modifiable risk factors like all the factors what we discussed so far like diet, exercise, smoking
which you can modify and have a healthy life style. This can substantially reduce the risk of you
getting heart attack.
Dr: I sincerely advise you to follow all the advices. We will keep following you up. If at any time
you develop chest pain or breathlessness, immediately call 999. If you have any of the
symptoms please call the ambulance and come to the hospital immediately because these are
the symptoms of serious condition. Is that okay Mr... ? Pt : Ok doctor.
Dr: Any other questions ? Pt : No doctor. You have been very kind.