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    Future Works PDF

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    Farhan Muhib
    1. Blood flow through arterial branches can be modeled and simulated using CT scans to generate 3D models. Simulations of the upper limb arteries showed accurate anatomical matching and validated flow parameters like wall pressure, wall shear stress, blood flow velocity, turbulence, and residence time. Abnormalities in branches can be identified without invasive procedures by examining simulation results. 2. Coronary artery bypass grafting simulations using patient CT scan data can model graft geometries and flow distributions pre-operatively to determine the best surgical procedure without invasive studies. Within 5 years, 10% of grafts become occluded, so simulations examine progression of coronary disease and choose the most appropriate bypass method.

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    Future Works PDF

    Uploaded by

    Farhan Muhib
    26 views3 pages
    1. Blood flow through arterial branches can be modeled and simulated using CT scans to generate 3D models. Simulations of the upper limb arteries showed accurate anatomical matching and validated flow parameters like wall pressure, wall shear stress, blood flow velocity, turbulence, and residence time. Abnormalities in branches can be identified without invasive procedures by examining simulation results. 2. Coronary artery bypass grafting simulations using patient CT scan data can model graft geometries and flow distributions pre-operatively to determine the best surgical procedure without invasive studies. Within 5 years, 10% of grafts become occluded, so simulations examine progression of coronary disease and choose the most appropriate bypass method.

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    1. Blood flow through arterial branches can be modeled and simulated using CT scans to generate 3D models. Simulations of the upper limb arteries showed accurate anatomical matching and validated flow parameters like wall pressure, wall shear stress, blood flow velocity, turbulence, and residence time. Abnormalities in branches can be identified without invasive procedures by examining simulation results. 2. Coronary artery bypass grafting simulations using patient CT scan data can model graft geometries and flow distributions pre-operatively to determine the best surgical procedure without invasive studies. Within 5 years, 10% of grafts become occluded, so simulations examine progression of coronary disease and choose the most appropriate bypass method.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    26 views3 pages

    Future Works PDF

    Uploaded by

    Farhan Muhib
    1. Blood flow through arterial branches can be modeled and simulated using CT scans to generate 3D models. Simulations of the upper limb arteries showed accurate anatomical matching and validated flow parameters like wall pressure, wall shear stress, blood flow velocity, turbulence, and residence time. Abnormalities in branches can be identified without invasive procedures by examining simulation results. 2. Coronary artery bypass grafting simulations using patient CT scan data can model graft geometries and flow distributions pre-operatively to determine the best surgical procedure without invasive studies. Within 5 years, 10% of grafts become occluded, so simulations examine progression of coronary disease and choose the most appropriate bypass method.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    of 3

    1.

    Blood flow Distribution through Artery Branches


    With proper CT scan reports arterial branches can be modeled in three dimension. A study is
    done on the arteries of upper limb of human which showed precise anatomical resemblance and
    was validated by experts1 (Fig. 1).

    Figure 1 Blood flow velocity through multiple branches of upper limb artery

    These simulations can be done for any arterial branch and hemodynamic parameters like-
    i. Wall pressure,
    ii. Wall shear stress,
    iii. Blood flow velocity,
    iv. Flow turbulence,
    v. Blood residence time, etc.

    Using these parameters, abnormality in any branch can be easily found without any invasive
    procedure. Artery walls experiencing abnormal pressure can be identified from the simulation
    result. Also, the flow divergence at the bifurcations and the distribution of flow rate through the
    arteries can be observed.
    2. Simulation of Coronary Artery Bypass Grafting
    5% of grafts are generally destined to become occluded within 1 year and 10% of them within 5
    years2. One of the most important determinants of successful bypass surgery is the flow field
    geometry and flow distribution in the neighborhood of the junction of the arteries. Most of the
    time pre-operation studies are done using invasively or by observing dye flow. To avoid these,
    CFD can be used by extracting data from CT scan images3. Detailed studies are done to
    investigate progression of coronary disease and the choice of the most appropriate surgical
    procedure4.

    Figure 2 Designing different kinds of bypass grafts before operating to find the
    best procedure.
    References
    1. Quanyu, W., Xiaojie, L., Lingjiao, P., Weige, T. & Chunqi, Q. SIMULATION ANALYSIS OF
    BLOOD FLOW IN. 29, 1–8 (2017).
    2. Song, M., Sato, M. & Ueda, Y. Three-Dimensional Simulation of Coronary Artery Bypass
    Grafting. 993–998 (2000).
    3. Hajati, O., Zarrabi, K., Karimi, R. & Hajati, A. CFD Simulation of Hemodynamics in
    Sequential and Individual Coronary Bypass Grafts Based on Multislice CT Scan Datasets.
    641–644 (2012).
    4. Ballarin, F. et al. Numerical modeling of hemodynamics scenarios of patient-specific
    coronary artery bypass grafts. Biomech. Model. Mechanobiol. 16, 1373–1399 (2017).

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