Unit 8 Reproductive System Pathological Conditions

UNIT 8
Reproductive System
Pathological Conditions
Female Reproductive System
CANDIDIASIS
 Vaginal fungal infection caused by Candida
albicans; characterized by a curdy or cheeselike
discharge and extreme itching.
CERVICITIS
 Inflammation of the uterine cervix.
 Cervicitis is usually the result of infection or a sexually
transmitted disease. It may also become chronic, because
the cervical lining is not renewed each month as is the
uterine lining during menstruation.
ECTOPIC PREGNANCY
 Implantation of the
fertilized ovum outside of
the uterine cavity.
 Ectopic pregnancy occurs in
approximately 1% of
pregnancies, most
commonly in the oviducts
(tubal pregnancy). Some
types of ectopic pregnancy
include ovarian, interstitial,
and isthmic.
ENDOMETRIOSIS
 Presence of endometrial tissue outside (ectopic) the
uterine cavity, such as the pelvis or abdomen.
FIBROID
 Benign neoplasm in the
uterus that is composed
largely of fibrous tissue;
also called leiomyoma.
 Uterine fibroids are the
most common tumors in
women. If fibroids grow
too large and cause
symptoms such as pelvic
pain or menorrhagia,
hysterectomy may be
indicated.
LEUKORRHEA
 White discharge from the vagina.
 A greater than usual amount of leukorrhea is normal in
pregnancy, and a decrease is to be expected after
delivery, during lactation, and after menopause.
Leukorrhea is the most common reason women seek
gynecological care.
OLIGOMENORRHEA
 Scanty or infrequent menstrual flow.
PREGNANCY-INDUCED HYPERTENSION (PIH)
 Potentially life-threatening disorder that usually

develops after the 20th week of pregnancy and is
characterized by edema and proteinuria.
 PIH may occur in nonconvulsive or convulsive forms.
PREECLAMPSIA
 Nonconvulsive form of PIH.
 If left untreated, preeclampsia may progress to
eclampsia. Treatment includes bed rest and blood
pressure monitoring.
ECLAMPSIA
 Convulsive form of PIH.
 Treatment for eclampsia includes bed rest, blood pressure
monitoring, and antiseizure drugs.
PYOSALPINX
 Pus in the fallopian tube.
RETROVERSION
 Turning, or state of being
turned back, especially
an entire organ being
tipped from its normal
position (such as the
uterus).
 Uterine retroversion is
measured as first-, second-
, or third-degree,
depending on the angle of
tilt in relationship to the
vagina.
STERILITY
 Inability of a woman to become pregnant or for a
man to impregnate a woman.
TOXIC SHOCK SYNDROME (TSS)
 Rare and sometimes fatal staphylococcus infection
that generally occurs in menstruating women, most
of whom use vaginal tampons for menstrual
protection.
 In TSS, the normally harmless vaginal bacterium
Staphylococcus aureus multiplies in the old blood in the
tampon and releases toxins. The tampon itself creates
small tears in the vaginal wall that allow the toxins to
enter the blood.
TRICHOMONIASIS
 Protozoal infestation of the vagina, urethra, or
prostate.
Male Reproductive System
ANORCHISM
 Congenital absence of one or both testes; also
called anorchia.
BALANITIS
 Inflammation of the
skin covering the
glans penis.
 Balanitis is caused by
irritation and invasion
of microorganisms. It
is commonly
associated with
inadequate hygiene of
the prepuce and
phimosis.
CRYPTORCHIDISM
 Failure of one or both
testicles to descend into
the scrotum.
 Cryptorchidism is
associated with a high
risk of sterility, causing a
low sperm count and male
infertility. If testes do not
descend on their own at
an early age, orchiopexy
is performed to bring the
testicles into the scrotum.
EPISPADIAS
 Congenital defect in which the
urethra opens on upper side
of the penis near the glans
penis instead of the tip.
HYPOSPADIAS
 Congenital defect in
which the male urethra
opens on underside of
the penis instead of the
tip.
IMPOTENCE
 Inability of a man to achieve or maintain a penile
erection; commonly called erectile dysfunction.
PHIMOSIS
 Stenosis or narrowness of the preputial orifice so
that the foreskin cannot be pushed back over the
glans penis.
Sexually Transmitted Diseases
SEXUALLY TRANSMITTED DISEASE (STD)
 Any disease that may be acquired as a result of

sexual intercourse or other intimate contact with an
infected individual and affects the male and female
reproductive systems; also called venereal disease.
CHLAMYDIA
 STD caused by infection with the
bacterium Chlamydia
trachomatis.
 Chlamydia is the most prevalent and
among the most damaging of all
STDs. In women, chlamydial infections
cause cervicitis with a mucopurulent
discharge and an alarming increase in
pelvic infections. In men, chlamydial
infections cause urethritis with a
whitish discharge from the penis.
GENITAL WARTS
 Wart(s) in the genitalia caused by human
papillomavirus (HPV).
 In women, genital warts may be associated with cervical
cancer.
GONORRHEA
 Contagious bacterial infection that most commonly
affects the genitourinary tract and, occasionally, the
pharynx or rectum.
 Gonorrheal infection results from contact with an infected
person or with secretions containing the causative
organism Neisseria gonorrhoeae. In men, symptoms
include dysuria and a greenish yellow discharge from the
urethra. In women, the chief symptom is a vaginal
greenish yellow discharge. Gonorrhea can be transmitted
to the fetus during delivery.
HERPES GENITALIS
 Infection in females and males of the genital and
anorectal skin and mucosa with herpes simplex virus
type 2.
 This viral infection may be transmitted to the fetus during
delivery and may be fatal.
SYPHILIS
 Infectious, chronic STD characterized by lesions that
change to a chancre and may involve any organ or
tissue.
 Syphilis usually exhibits cutaneous manifestations and
relapses are common without treatment. It may exist
without symptoms for years and can be transmitted from
mother to fetus.
Diagnostic Procedures
Female
AMNIOCENTESIS
 Obstetric procedure that involves surgical puncture of the
amniotic sac under ultrasound guidance to remove amniotic
fluid.
 In amniocentesis, cells of the fetus found in the fluid are cultured and
studied chemically and cytologically to detect genetic abnormalities,
biochemical disorders, and maternal-fetal blood incompatibility.
COLPOSCOPY
 Examination of the vagina and cervix with an
optical magnifying instrument (colposcope).
 Colposcopy is commonly performed after a Papanicolaou
test to obtain biopsy specimens of the cervix.
HYSTEROSALPINGOGRAPHY
 Radiography of the uterus and oviducts after
injection of a contrast medium.
LAPAROSCOPY
 Visual examination of the abdominal cavity with a
laparoscope through one or more small incisions in the
abdominal wall, usually at the umbilicus.
 Laparoscopy is used for inspection of the ovaries and
fallopian tubes, diagnosis of endometriosis, destruction of
uterine leiomyomas, myomectomy, and gynecologic
sterilization.
MAMMOGRAPHY
 Radiography of breast; used to diagnose benign
and malignant tumors.
PAPANICOLAOU (PAP) TEST
 Microscopic analysis of cells taken from the cervix
and vagina to detect the presence of carcinoma.
 Cells are obtained for a Pap test via insertion of a
vaginal speculum and the use of a swab to scrape a
small tissue sample from the cervix and vagina.
ULTRASONOGRAPHY (US)
 Imaging technique that uses high-frequency sound
waves (ultrasound) that bounce off body tissues and
are recorded to produce an image of an internal
organ or tissue.
 Pelvic US is used to evaluate the female reproductive
organs and the fetus during pregnancy. Transvaginal US
places the sound probe in the vagina instead of across
the pelvis or abdomen, producing a sharper examination
of normal and pathologic structures within the pelvis.
ULTRASONOGRAPHY (US)
Diagnostic Procedures
Male
DIGITAL RECTAL EXAMINATION (DRE)
 Examination of the prostate gland by finger

palpation through the anal canal and the rectum.
 DRE is usually performed during physical examination to
detect prostate enlargement. It is also used to check for
problems with organs or other structures in the pelvis and
lower abdomen.
PROSTATE-SPECIFIC ANTIGEN (PSA) TEST
 Blood test to screen for prostate cancer.

 Elevated levels of PSA are associated with prostate
enlargement and cancer.
Medical and Surgical Procedures
Female
CERCLAGE
 Obstetric procedure in which a nonabsorbable
suture is used for holding the cervix closed to
prevent spontaneous abortion in a woman who has
an incompetent cervix.
DILATION AND CURETTAGE (D&C)
 Surgical procedure that widens the cervical canal of
the uterus (dilation) so that the endometrium of the
uterus can be scraped (curettage).
 D&C is performed to stop prolonged or heavy uterine
bleeding, diagnose uterine abnormalities, and obtain
tissue for microscopic examination. It is also performed
to remove tumors, rule out carcinoma of the uterus,
removed retained placental fragments after delivery or
after an incomplete abortion, and determine the cause of
infertility.
DILATION AND CURETTAGE (D&C)
HYSTEROSALPINGO-OOPHORECTOMY
 Surgical removal of a uterus, a fallopian tube, and

an ovary.
LUMPECTOMY
 Excision of a small primary breast
tumor (“lump”) and some of the
normal tissue that surrounds it.
 In lumpectomy, lymph nodes may also
be removed because they are located
within the breast tissue taken during
surgery. All tissue removed from the
breast is biopsied to determine whether
cancer cells are present in the normal
tissue surrounding the tumor.
Lumpectomy is the most common form
of breast cancer surgery today.
MASTECTOMY
 Complete or partial
excision of one or both
breasts, most commonly
performed to remove a
malignant tumor.
 Mastectomy may be
simple, radical, or
modified depending on
the extent of the
malignancy and amount
of breast tissue excised.
TOTAL MASTECTOMY
 Excision of an entire breast, nipple, areola, and the
involved overlying skin; also called simple
mastectomy.
 In total mastectomy, lymph nodes are removed only of
they are included in the breast tissue being removed.
MODIFIED RADICAL MASTECTOMY
 Excision of an entire breast, including lymph nodes
in the underarm (axillary dissection).
 Most women who have mastectomies today have
modified radical mastectomies.
RADICAL MASTECTOMY
 Excision of an entire breast, all underarm lymph
nodes, and chest wall muscles under the breast.
RECONSTRUCTIVE BREAST SURGERY
 Reconstruction of a breast that has been removed

due to cancer or other disease.
 Reconstruction is commonly possible immediately
following mastectomy so the patient awakens from
anesthesia with a breast mound already in place.
TISSUE (SKIN) EXPANSION
 Common breast reconstruction technique in which a
balloon expander is inserted beneath the skin and
chest muscle, saline solution is gradually injected to
increase size, and the expander is then replaced
with a more permanent implant.
TRANSVERSE RECTUS ABDOMINIS
MUSCLE (TRAM) FLAP
 Surgical creation of a skin
flap (using skin and fat from
the lower half of the
abdomen), which is passed
under the skin to the breast
area, shaped into a natural-
looking breast, and sutured
into place.
 The TRAM flap procedure is
one of the most popular
reconstruction options.
TUBAL LIGATION
 Sterilization procedure that involves blocking both
fallopian tubes by cutting or burning them and tying
them off.
Medical and Surgical Procedures
Male
CIRCUMCISION
 Surgical removal of
the foreskin or
prepuce of the
penis, usually
performed on the
male as an infant.
TRANSURETHRAL RESECTION OF THE
PROSTATE (TURP)
 Surgical procedure to relieve obstruction caused by
benign prostatic hyperplasia (excessive overgrowth of
normal tissue) by insertion of a resectoscope into the
penis and through the urethra to “chip away” at
prostatic tissue and flush out chips (using an irrigation
solution).
 The pieces of prostatic tissue obtained through TURP are sent
to the laboratory to be analyzed for possible evidence of CA.
Although TURP relieves the obstruction, overgrowth of tissue
may recur over several years. Lasers may also be used to
destroy prostatic tissue and relieve obstruction.
TRANSURETHRAL RESECTION OF THE
PROSTATE (TURP)
GONADOTROPIN
 Hormonal preparation used to increase sperm count
in infertility cases.

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UNIT 8

 Potentially life-threatening disorder that usually

 Any disease that may be acquired as a result of

 Examination of the prostate gland by finger

 Blood test to screen for prostate cancer.

 Surgical removal of a uterus, a fallopian tube, and

 Reconstruction of a breast that has been removed

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