Animal Hormones PDF
Animal Hormones PDF
Animal Hormones PDF
Thymus
Major
glands of Thyroid &
Parathyroid
endocrine glands
Gonads system
Pineal gland
Adrenal gland
Hormones are chemical signals
• Only target cell can respond to specific hormones .
• A target cell carries receptor protein to bind with particular
hormones.
• The receptor protein bind with hormone like the way key fits a locks.
After that , the target cell respond to that hormone.
Androgen sensitivity
✓An individual has X and Y sex chromosomes , and the testes remain in
the abdominal cavity , produces sex hormone testosterone .
✓However, body cells lack of receptors that are able to combine with
testosterone , and the individual appears to a normal female.
Pheromones
• Chemical signals that influence the behavior of other individuals.
• The hormones have been well documented in several animal species
even though their influence have been more difficult to prove in
human.
• Women who lives in a same household tend to have synchronized
menstrual cycle .
• The pheromones released by a women who is menstruating affect the
menstrual cycle of other women in the house.
The Action of Hormones
• Hormones exert a wide range of effects on cells.
• Some induce target cells to increase the uptake of particular molecule
while some brings alternation of the target cell’s in some way.
• Endocrine glands secrete Peptide Hormones (proteins, glycoproteins,
modified amino acid)
• Steroid Hormones are derived from Cholesterol thus all have same
molecular complex of four carbon ring.
The Action of Peptide
Hormones
• In muscle cells, epinephrine will binds to a
rceptor in the plasma membrane.
• The immediate result of epinephrine bindin is
the formation of cyclic adenosine
monophosphate (CAMP)
• cAMP will activates a protein kinase enzyme in
the cell and that enzyme will activate another
enzyme and so forth. (Enzyme Cascade)
• Thus will break glycogen down to glucose
which will enter the bloodstream.
The Action of Steroid Hormones
• Only adrenal cortex, the ovaries and the testis produce
steroid hormones.
• Steroid hormones did not bind to plasma membrane
receptor as they are able to enter the cell since they
are lipid.
• Once inside, a steroid hormones binds to an internal
receptor (nucleus/cytoplasm).
• Inside the nucleus, the hormones-receptor complex
binds with DNA and activates certain genes.
• mRNA moves to the ribosomes in cytoplasm followed
by protein synthesis (e.g. enzyme)
• Steroids act more slowly than peptide because it takes
more time to synthesize new protein than to activate
enzymes already present in cells. Their action however
last longer.