Chemdraw Kimia Medisinal
Chemdraw Kimia Medisinal
Chemdraw Kimia Medisinal
Membuat Gambar Struktur Kimia 2D dan Memberi Nama IUPAC dari Senyawa Obat
O
O NH2
S
O
F
N
OH N
F
OH
salicylic acid
2-hydroxybenzoic acid
celecoxib
4-(5-(p-tolyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide
O
HO
O
O
O
H
simvastatin
(1R,3S,7R,8R,8aS)-8-(2-((2R,4S)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-3,7-dimethyl-
1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2,2-dimethylbutanoate
HO O
OH
O H
ibuprofen
N
2-(4-isobutylphenyl)propanoic acid
HO
morphine
(4R,4aR,7S,7aR,12bS)-3-methyl-2,3,4,4a,7,7a-hexahydro-1H-
4,12-methanobenzofuro[3,2-e]isoquinoline-7,9-diol
B. Menggambar Struktur Senyawa dari Template
1. Amino Acids
O H2N CH C OH
H 2N CH C OH CH2
CH3 CH2
alanine CH2
NH
C NH
NH2
arginine
2. DNA Template
NH2
N
N
N
N
HO
O
H H
H H
OH H
(2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol
Adeninedeoxyribosenucleoside
N
NH
N
O N NH2
-
O P O
O
O- H H
H H
OH H
((2R,3S,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3-hydroxytetrahydrofuran-2-
yl)methyl phosphate
Guaninedeoxyribosenucleoside
3. RNA Template
NH2
N O
HO
O
H H
H H
OH OH
4-amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one
Cytosineribonucleoside
NH
N O
O
-
O P O
O
O - H H
H H
OH OH
((2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl
phosphate
Uracilribonucleotide
4. Hexoses
CHO
H OH
HO H
H OH
H OH
CH2OH
(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanal
D-glucose
H OH
H O
HO
HO H
H OH
H OH
(2S,3R,4S,5S,6R)-6-(hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol
D-glucose bentuk -pyranose
H OH
H O
HO
H OH
H OH
OH H
(2R,3R,4R,5S,6R)-6-(hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol
D-glucose bentuk -pyranose
H
H
HO O
HO
HO H
H OH
H OH
(2S,3R,4R,5R)-5-((R)-1,2-dihydroxyethyl)tetrahydrofuran-2,3,4-triol
D-glucose a-furanose
H
OH
HO O
HO
HO H
H H
H OH
(2R,3R,4R,5R)-5-((R)-1,2-dihydroxyethyl)tetrahydrofuran-2,3,4-triol
D-glucose bentuk -furanose
OH N+
O O-
Cl
N
H
Cl OH
chloramphenicol
2,2-dichloro-N-((1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl)acetamide