Drug Study

Name of Drug Classification of Mechanism of Action Indication Contraindications Side Effects Nursing Responsibilities
Drug
Generic Therapeutic: Exact mechanism is Adjunct to diet to lower Contraindicated  Endocrine: Hypoglyc o History: Allergy
Name: Antidiabetic not understood; blood glucose with type with allergy emia, lactic acidosis to metformin; diabetes
metformin hy possibly increases 2 (non–insulin- to metformin;  GI: Anorexia, complicated by fever,
drochloride Pregnancy peripheral utilization dependent) diabetes CHF; diabetes nausea, vomiting, e severe infections, severe
Trade Name: Category B of glucose, decreases mellitus in patients complicated by pigastric discomfort trauma, major surgery,
Glucophage, hepatic glucose fever, severe , heartburn, ketosis, acidosis, coma;
Glucophage X production and alters infections, severe diarrhea, flatulence type 1 diabetes, serious
R intestinal absorption trauma, major  Hypersensitivity: All hepatic or renal
Availability: of glucose. surgery, ketosis, ergic skin impairment, uremia,
Tablets—500, acidosis, coma reactions, eczema, thyroid or endocrine
850, (use insulin); type pruritus, erythema, impairment, glycosuria,
1,000 mg; ER 1 (insulin- urticaria hyperglycemia associated
tablets— dependent), with primary renal
500 mg serious hepatic disease, CHF, pregnancy,
impairment, lactation.
serious renal  Do not discontinue this
impairment, medication without
uremia, thyroid or consulting your health
endocrine care provider.
impairment, glycos o Monitor urine or blood
uria, for glucose
hyperglycemia and ketones as
associated with prescribed.
primary renal
disease;
 o Swallow ER tablets
whole; do not cut, crush,
or chew.
o Do not use this drug
during pregnancy; if you
become pregnant,
consult with your health
care provider for
appropriate therapy.
o Avoid using alcohol while
taking this drug.
o Report fever, sore throat,
unusual bleeding or
bruising, rash, dark urine,
light-colored stools,
hypo- or hyperglycemic
reactions.

Name of Drug Classification of Mechanism of Action Indication Contraindication Side Effects Nursing Responsibilities
Drug

Generic Classification: Omeprazole is Omeprazole is used to Contraindicated Diarrhea, nausea, Caution patient to swallow
Name: Proton Pump a proton pump treat symptoms with fatigue, constipation, capsules whole—not to open,
Omeprazole Inhibitor (PPI) inhibitor that inhibits of gastroesophageal hypersensitivity to vomiting, flatulence, chew, or crush them. Arrange
secretion of gastric reflux disease (GERD) omeprazoleor its acid regurgitation, taste for further evaluation of
Brand Name: acid by irreversibly and other conditions components;Use perversion, arthralgia, patient after 8 weeks of
Omepron blocking the enzyme caused by excess cautiously with myalgia, urticaria, dry therapy for gastro reflux
system stomach acid. It is also pregnancy,lactatio mouth, dizziness, disorders; not intended for
of hydrogen/potassiu used to promote healing n. headache, maintenance therapy.
 m adenosine of erosive paraesthesia, Administer antacids with
triphosphatase, the esophagitis (damage to abdominal pain, skin omeprazole, if needed.
“proton pump” of the your esophagus caused rashes, weakness, back Teaching points: Take the
gastric parietal cell. by stomach acid). pain, upper respiratory drug before meals. Swallow
The drug is used in infection, cough. the capsules whole; do not
conditions, where chew, open, or crush them.
the inhibition of This drug will need to be
gastric acid secretion Potentially taken for up to 8wk (short-
may be beneficial, Fatal: Anaphylaxis. term therapy) or for a
including aspiration prolonged period(> 5 yr in
syndromes, dyspepsia some cases).Have regular
, gastro-oesophageal medical follow-up visits.
reflux disease, and
peptic ulcer disease.
The dose of
Omeprazole may
need to be reduced
in patients with
hepatic impairment

References:

https://www.sciencedirect.com/topics/neuroscience/omeprazole
https://www.webmd.com/drugs/2/drug-11285-7061/metformin-oral/metformin-oral/details