Immune System As Biology Questions AQA OCR Edexcel
Immune System As Biology Questions AQA OCR Edexcel
Immune System As Biology Questions AQA OCR Edexcel
A Level
A Level Biology
The Immune System Questions
Name:
1. The immune system is a biological defence that protects the body from potentially harmful
substances by recognising invading pathogens and responding to them appropriately.
a)
i) What is the definition of a pathogen and give two examples. (3 marks)
b) In order for a pathogen to become established in an organism, it must first get past the
organisms primary defences. The skin is one example of a primary defence.
i) How has the human digestive system evolved to defend itself from pathogens?
(2 marks)
ii) How has the human respiratory system adapted to defend itself from pathogen
invasion? (2 marks)
b) Phagocytes then activate T cells. T cells have receptors that are complementary to
antigens on the surface of cells.
ii) When an antigen binds to a receptor on a T cell, the T cell becomes activated and
differentiates into different types of T cells. What are these T cells and what are their
functions? (6 marks)
c) B cells are involved in the final stage of the immune response. Once activated they
differentiate into plasma cells and memory cells. The plasma cell surface is covered with
antibodies. The diagram below shows the structure of an antibody.
Variable Region
vi) What is meant by the term ‘agglutination’ in reference to antibody action? (3 marks)
d) What is meant by the terms cellular response and humoral response? (2 marks)
3. The body’s immune response changes over time as a result of exposure to different
pathogens.
a) The graph below shows how the concentration of an antibody changes in the blood over a
period of time. The red arrow indicates exposure to the same antigen.
Concentration of a
A
specific antibody in
B
the blood
Time in days