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    Bleeding Disorders Investigation

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    Varshaa Bharathi
    This document defines and provides testing methods and normal values for various tests used to evaluate bleeding disorders and platelet function. Some of the key tests described are bleeding time, which measures platelet function and clot formation; prothrombin time and activated partial thromboplastin time, which evaluate the intrinsic and extrinsic coagulation pathways; and thrombin time, which assesses the final stage of coagulation. Normal ranges are provided to interpret test results.

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    Bleeding Disorders Investigation

    Uploaded by

    Varshaa Bharathi
    86 views2 pages
    This document defines and provides testing methods and normal values for various tests used to evaluate bleeding disorders and platelet function. Some of the key tests described are bleeding time, which measures platelet function and clot formation; prothrombin time and activated partial thromboplastin time, which evaluate the intrinsic and extrinsic coagulation pathways; and thrombin time, which assesses the final stage of coagulation. Normal ranges are provided to interpret test results.

    Original Description:

    Here is an easy tabulation showing different investigations for bleeding disorders

    Original Title

    Bleeding disorders investigation

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    This document defines and provides testing methods and normal values for various tests used to evaluate bleeding disorders and platelet function. Some of the key tests described are bleeding time, which measures platelet function and clot formation; prothrombin time and activated partial thromboplastin time, which evaluate the intrinsic and extrinsic coagulation pathways; and thrombin time, which assesses the final stage of coagulation. Normal ranges are provided to interpret test results.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    86 views2 pages

    Bleeding Disorders Investigation

    Uploaded by

    Varshaa Bharathi
    This document defines and provides testing methods and normal values for various tests used to evaluate bleeding disorders and platelet function. Some of the key tests described are bleeding time, which measures platelet function and clot formation; prothrombin time and activated partial thromboplastin time, which evaluate the intrinsic and extrinsic coagulation pathways; and thrombin time, which assesses the final stage of coagulation. Normal ranges are provided to interpret test results.

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    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
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    Bleeding Disorders

    Definition Methods Normal Value


    Bleeding Time Bleeding time is a Duke’s method, Duke method:
    laboratory test to assess Ivy’s method and 1-5 min
    platelet function and the template method Ivy method: 5-
    body’s ability to form a clot 11 min
    Template
    method: 2-9 min
    Capillary Fragility Test This test measures the Hess 0-5 petechiae
    ability of the capillaries to Test/Tourniquet
    withstand increased stress test
    Platelet aggregation test This test measures the - -
    ability of platelets to
    aggregate in response to
    agonist like thrombin
    Platelet adhesiveness test This test measures the - The normal
    ability of platelets to range is 75% to
    adhere to glass surface 95% of platelet
    retention
    Clotting Time It measures the time taken Lee-white method 4-11 min
    for the fresh blood to clot
    Prothrombin time Prothrombin time (PT) is Quick’s one stage 11-16 seconds
    the time taken for citrated prothrombin time
    plasma to clot after the
    addition of tissue
    thromboplastin and
    calcium
    Prothrombin This test is performed to - -
    Consumption test determine the quantity of
    prothrombin remaining in
    the serum after clot is
    formed
    Partial thromboplastin It is a measure of intrinsic - 60-80 seconds
    time and common coagulation
    pathways
    Activated Partial APTT is the time taken for - 30-40 seconds
    thromboplastin time citrated plasma to clot in
    the presence of a surface
    activator (Kaolin),
    phospholipid and calcium
    Thrombin Time Thrombin time detects the - 15 to 20 seconds
    effectiveness of the final
    stage of coagulation in
    which fibrinogen is
    converted to fibrin
    Plasma recalcification A measure of the time - Platelet rich
    time taken for clot formation in plasma:100 to
    recalcified blood 150 seconds
    Platelet poor
    plasma:135 to
    240 seconds
    Clot retraction time It assess the clot stability - Normal clot
    and platelet functions retraction
    shows more
    than 50% of
    serum at end of
    24 hrs

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