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    006 Pathology MCQ ACEM Primary Cellular

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    Irum Rafeeq
    This document contains 11 multiple choice questions about pathology. The questions cover topics like hypoxic cell injury, apoptosis, reversible cell injury, fatty change, metastatic calcification, mechanisms of cellular adaptation, acute inflammation, angiogenesis, the mononuclear phagocyte system, and primary wound healing. The answers to each question are provided at the end.

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    © All Rights Reserved
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    006 Pathology MCQ ACEM Primary Cellular

    Uploaded by

    Irum Rafeeq
    551 views5 pages
    This document contains 11 multiple choice questions about pathology. The questions cover topics like hypoxic cell injury, apoptosis, reversible cell injury, fatty change, metastatic calcification, mechanisms of cellular adaptation, acute inflammation, angiogenesis, the mononuclear phagocyte system, and primary wound healing. The answers to each question are provided at the end.

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    This document contains 11 multiple choice questions about pathology. The questions cover topics like hypoxic cell injury, apoptosis, reversible cell injury, fatty change, metastatic calcification, mechanisms of cellular adaptation, acute inflammation, angiogenesis, the mononuclear phagocyte system, and primary wound healing. The answers to each question are provided at the end.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    551 views5 pages

    006 Pathology MCQ ACEM Primary Cellular

    Uploaded by

    Irum Rafeeq
    This document contains 11 multiple choice questions about pathology. The questions cover topics like hypoxic cell injury, apoptosis, reversible cell injury, fatty change, metastatic calcification, mechanisms of cellular adaptation, acute inflammation, angiogenesis, the mononuclear phagocyte system, and primary wound healing. The answers to each question are provided at the end.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
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    The document discusses cellular pathology concepts like hypoxic cell injury, apoptosis, fatty change, and wound healing processes.

    Reversible cell injury is characterized by cellular swelling, reduced ATP synthesis and pH while irreversible changes like fatty change are permanent. Apoptosis involves chromatin condensation.

    Macrophage infiltration, neovascularization and collagen deposition and remodeling are involved in wound healing. Strength returns to 25% of normal by the first week.

    Pathology MCQs

    1. In hypoxic cell injury, cell swelling occurs because of increased intracellular:

    Answer A lipid

    AnswerB protein

    Answer C glycogen

    AnswerD lipofuscin

    Answer E water

    2. Which of the following is a feature of apoptosis?

    Answer A Karyolysis

    AnswerB Cellular swelling

    Answer C Involvement of a large number of cells

    AnswerD Chromatin condensation

    Answer E Associated inflammatory changes

    3. Which of the following is NOT a feature of reversible cell injury?

    Answer A Cellular swelling

    AnswerB Reduction of ATP synthesis

    Answer C Reduced cellular pH

    Ans)verD Clumping of nuclear chromatin

    Answer E Defects in cell membrane


    4. Fatty change:

    Answer A Is irreversible

    AnswerB Does not impair cellular function

    Answer C Is most commonly due to diabetes

    AnswerD Is caused by alcohol by an increase in intracellular alpha


    glycero phosphate

    Answer E Only occurs in the liver

    5. Metastatic calcification:

    Answer A Is encountered in areas of necrosis.

    AnswerB Commonly develops in aging or damaged heart valves.

    Answer C Can occur with normal serum levels of calcium.

    AnswerD Can be associated with metastatic malignancy.

    Answer E Is commonly associated with hypoparathyroidism.

    6. Regarding apoptosis, which of the following is FALS E?

    Answer A It is the responsible for programmed destruction of cells during


    embryogenesis.

    AnswerB Occurs in pathologic atrophy in parenchymal organs after duct


    destruction.

    Answer C Cell death by cytotoxic T cells.

    AnswerD Associated with inflammation

    Answer E Chromatin condensation and fragmentation are features.


    7. With regard to mechanisms of cellular adaptation, which of the following
    statements is TRU E?

    Answer A Hyperplasia refers to an increase in cell size.

    AnswerB TNF always acts as an inhibitor of hyperplasia.

    Answer C The myocardium adapts to increased workload by


    hypertrophy and hyperplasia.

    AnswerD Metaplasia is irreversible.

    Answer E Barrett's metaplasia is squamous to columnar epithelium in the


    distal oesophagus

    8. With regard to acute inflammation which of the following is FALS E?

    Answer A P avementing of leukocytes must occur.

    Answer B The loss of protein from plasma reduces intravascular osmotic


    pressure.

    Answer C Transmigration of leukocytes occurs as a result of pseudopod


    formation.

    AnswerD P -selectin is found in Weibel-palade bodies.

    AnswerE Leukocyte diapedesis occurs predominantly in the venules.

    9. Which of the following statements about angiogenesis is FALS E?

    Answer A PDGF selectively induces hyperplasia of lymphatic tissue

    Answer B New vessels bud from pre-existing vessels.

    Answer C There is proteolytic degradation of the parent vessel basement


    membrane.

    AnswerD New vessels are leaky due to incompletely formed


    inter-endothelial junctions.

    AnswerE VEGF receptors are largely restricted to endothelial cells.


    10. In the mononuclear phagocyte system:

    Answer A Aggregations of macrophages in the kidney are known as


    Kupffer cells.

    AnswerB The life span of tissue macrophages is about three days.

    Answer C The half-life of blood monocytes is about one month.

    Answer D Chemotactic stimuli for monocytes include C5a and certain


    growth factors.

    AnswerE Monocytes transform into smaller macrophages when they

    reach extravascular tissue.

    11. In primary wound healing:

    Answer A Macrophage infiltration occurs at 24hrs

    AnswerB Wound strength is 25% of normal at the end of first week

    Answer C Type I collagen is replaced by type III collagen

    Answer D Neovascularisation is maximal at day five

    AnswerE All of the above


    Answers Pathology

    1. E

    2. D

    3. E

    4. D

    5. D

    6. D

    7. E

    8. A

    9. A

    10. D

    11. D

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