2019 15 Notifn DrugsInspector JuniorAnalyst
2019 15 Notifn DrugsInspector JuniorAnalyst
2019 15 Notifn DrugsInspector JuniorAnalyst
COMMISSION
Advertisement No.544
Notification No. 15 / 2019 DATED:12 .04.2019
Applications are invited from eligible candidates only through online mode upto 12.05.2019 for
direct recruitment to the posts of Drugs Inspector in the Tamil Nadu Medical Service and
Junior Analyst in the Tamil Nadu Medical Subordinate Service.
No. of
Name of the post Name of the service Scale of pay
vacancies
Rs.37700 - 119500
Drugs Inspector Tamil Nadu Medical 40
(Level 20) as per the
(Post Code No. 1972) Service (2017-2019)
Tamil Nadu Revised
(Service Code No. 048)
Pay Rules, 2017
The number of vacancies is only approximate and is liable for modification including
reduction with reference to vacancy position at any time before admitting the applicants to
oral test.
It is mandatory for applicants to register their basic particulars through one - time online
registration system on payment of Rs. 150/- (Rupees One hundred and fifty only) towards
registration fee and then they should apply online for this recruitment. [The one-time registration will
be valid for five years from the date of registration. Thereafter, the registration should be renewed by
paying the prescribed fee. One Time Registration will not be considered as an application for any
post.]
2. DISTRIBUTION OF VACANCIES
The category wise breakup details, in respect of the vacancies for the posts of Drugs Inspector
and Junior Analyst are as follows;
i) For the post of Drugs Inspector
SC(G)(DAP - LD,
BC(OBCM)(W)
CP,LC,DF,AC)
BC(OBCM)(G)
BC(OBCM)(G)
BC(OBCM)(G)
GT(G)(PSTM)
SC(G)(PSTM)
MBC/DC(W)
MBC/DC(W)
MBC/DC(G)
MBC/DC(G)
(DAP - LV)
BC(M)(W)
SC(A)(G)
(PSTM)
(PSTM)
(PSTM)
TOTAL
GT(W)
SC(W)
GT(G)
SC(G)
ST(G)
7 2 3 6 1 1 3 1 5 1 1 1 2 1 1 2 1 1 40
2
BC(OBCM)(G)
GT(W)(PSTM)
MBC/DC(W)
MBC/DC(G)
BC(M)(W)
TOTAL
GT(G)
SC(G)
2 1 2 1 1 1 1 9
Abbreviations:-
GT - General Turn; BC(OBCM) - Backward Classes (Other than Backward Class Muslims);
BC(M) - Backward Class Muslims; MBC/DC - Most Backward Classes / Denotified
Communities; SC - Scheduled Castes; SC(A) - Scheduled Castes (Arunthathiyars);
ST–Scheduled Tribes; G – General; W – Women; PSTM- Persons Studied in Tamil
Medium; DAP – Differently Abled Persons; LV – Low Vision; LD – Locomotor Disability;
CP – Cerebral Palsy; LC – Leprosy Cured; DF – Dwarfism; AC – Acid Attack Victims.
Note
4. QUALIFICATIONS:
(A) AGE LIMIT (as on 01.07.2019):
Explanation: No maximum age limit shall mean that the applicants should not have completed 58
years of age either on the date of notification or at the time of selection /appointment to the post.
Note
“Others” [i.e Applicants not belonging to SCs, SC(A)s, STs, MBCs/DCs, BC(OBCM)s,
BCMs] who have put in five years and more of service in the State/Central Government are not
eligible even if they are within the age limit.
(For further details refer to para 5 of “Instructions to Applicants”, Section 3(r) and Section
20(8) of Tamil Nadu Government Servants (Conditions of Service) Act, 2016)
AGE CONCESSION:
(i) For Differently Abled Persons :
Differently Abled Persons are eligible for age concession upto 10 years over and above the
maximum age limit prescribed.
(Section 64 of the Tamil Nadu Government Servants (Conditions of Service) Act, 2016)
(ii) For Ex-servicemen :
a) The maximum age limit for ex-servicemen is 48 years.
(Section 63 of the Tamil Nadu Government Servants (Conditions of Service) Act, 2016)
b) The above mentioned age concession will not apply to the ex-servicemen applicants
who have already been recruited to any class or service or category.
(Section 3(j) of the Tamil Nadu Government Servants (Conditions of Service) Act, 2016)
Applicants should possess the following or its equivalent qualification awarded by any
University or Institution recognized by the University Grants Commission:
Note:
(i) The qualification prescribed for the posts should have been obtained by passing the
required qualification in the following order of studies: 10th + HSC or its equivalent +
Bachelor‟s degree + Post-graduate degree as required under Section 25 of the Tamil Nadu
Government Servants (Conditions of Service) Act, 2016. Results of the examination should
have been declared on or before the date of notification. (Section 20(4)(iv) of the Tamil
Nadu Government Servants (Conditions of Service) Act, 2016).
(ii) With respect to the post of Junior Analyst, the qualifications considered equivalent are
indicated in Annexure-I to this notification.
(iii) Applicants claiming equivalence of qualification should upload and submit evidence for
equivalence of qualification, in the form of government order issued on or before the date of
this notification, and produce it when called for, failing which, their application will be
summarily rejected. The government orders regarding equivalence of qualification issued
after the date of this notification will not be accepted. (For further details regarding
equivalence of qualification refer to para.10 of the “Instructions to Applicants”).
(iv) With respect to the applicants who are applying for the post of Junior Analyst, they should
upload or submit experience certificate as provided in Annexure-II to this notification when
called for.
(C) CERTIFICATE OF PHYSICAL FITNESS:
Applicants selected for appointment to the posts will be required to produce a certificate of
physical fitness in the form prescribed below:
Form of certificate of
Sl. No. Name of the post Standard of vision
physical fitness
1. Drugs Inspector Form prescribed for
Standard-III or posts other than
2. Junior Analyst better Executive and
Ministerial posts
Applicants with defective vision should produce eye fitness certificate from a qualified eye
specialist.
5
5. FEES:
a) Registration Fee
Rs.150/-
For One Time Registration (Revised with effect from 01.03.2017 vide G.O.
(Ms).No.32, Personnel and Administrative Reforms (M) Department, dated
01.03.2017).
Note
Applicants who have already registered in One Time Registration system
within the validity period of 5 years are exempted.
b) Examination Fee
i) For candidates who are applying only for the post of Junior Analyst Rs.150/-
ii) For candidates who are applying only for the post of Drugs Inspector Rs.200/-
iii) For candidates who are applying for both the posts of Drugs Rs.200/-
Inspector and Junior Analyst.
Note
The Examination fee should be paid at the time of submitting the online
application for this recruitment if they are not eligible for the concession
noted below.
Note:
(i) Applicants who have registered under one - time registration system must pay the
prescribed examination fee for this recruitment. (One – time registration is only to avail
exemption from payment of registration fee for a period of five years from the date of
registration and it will not be considered as prescribed examination fee for this recruitment)
(ii) Applicants who had already registered under one time registration system by paying
Rs.50/- before 01.03.2017 and having validity are exempted from paying the registration
fee for this recruitment.
(ii) Differently Abled Persons and (i) For Differently Abled Persons, the
Destitute Widow of all disability should be not less than
communities 40%.
Full Exemption (ii) For DWs, the DW certificate
should have been obtained from
the RDO / Sub Collector /
Assistant Collector.
(iii) Most Backward Classes / Those who have not
Denotified Communities/ availed three free
Backward Classes (Other than chances so far in the Should not have availed three free
Muslims) / Backward Class previous recruitments chances in the previous recruitments.
(Muslim) may avail exemption
from payment of
examination fee.
(i) Ex-Servicemen Those who have not (i) Should not have availed two free
availed two free chances in the previous
chances so far in the recruitments.
previous recruitments (ii) Fee concession will not apply to
may avail exemption those who have already been
from payment of recruited to any class or service or
examination fee. category.
Note:
(i) The three / two free chances referred to above are not for EACH POST but for ANY THREE
/ TWO APPLICATIONS ONLY. The claim for exemption from payment of examination fee
made in any application which has been rejected / admitted or withdrawn will be counted as
free chance availed.
(ii) Failure to pay the prescribed fee along with the application in-time will result in the rejection
of application.
(iii) The number of free chances availed by the applicant means, the total number of free
chances hitherto availed by the applicant in his/her earlier applications submitted to the
Commission for any post / recruitment.
(iv) If the examination fee concession claimed in the application is found to exceed the
admissible limits, as announced above, the application will be rejected at any stage of
selection. The number of free chances availed by the applicants will be counted from all the
previous applications submitted through One Time Registration and / or submitted directly
without One Time Registration.
(For further details regarding examination fee concession, refer to para. 12 of the
“Instructions to Applicants”).
6. MODE OF PAYMENT OF FEE:
Examination fee of Rs.150/- (Rupees One hundred and fifty only) or Rs.200/- (Rupees
Two hundred only), as the case may be, is payable online through Net Banking / Credit
card / Debit card or it can be paid offline at the State Bank of India / Indian Bank within
two days from the date of submission of online application by choosing the option in the
online application.
Applicants have also to pay the service charges as applicable.
Offline mode of payment in the form of demand draft / postal order etc. will not be
accepted and the applications forwarded with such modes of payment will be summarily
rejected.
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7. CONCESSIONS:
(i) Concessions with regard to age and examination fees allowed to SCs, SC(A)s, STs,
MBCs/DCs, BC(OBCM)s, BCMs, Destitute Widows, Differently Abled Persons and
Ex-servicemen are given in paras. 12 to 14 of the 'Instructions to Applicants'.
(ii) Persons claiming concessions referred to above and other claims made in the application
have to produce evidence for such claims when called for, otherwise their application will
be rejected.
Note:
In all cases, an ex-serviceman once recruited to a post in any class or service or category,
cannot claim the concession of being called an ex-serviceman for his further recruitment.
(Section 3(j) of the Tamil Nadu Government Servants (Conditions of Service) Act, 2016)
Total 570
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* For those who have studied PG Degree in Chemistry with Analytical Chemistry as a special
subject.
Note:
a) The questions in Paper-I (subject paper of all the above mentioned subjects except
Chemistry) will be set in English only and questions in Paper-I with respect to the subject
Chemistry and Paper-II ”General Studies” will be set both in English and in Tamil.
b) Refer to para 22 of “Instructions to Applicants” in regard to Instructions to be followed while
appearing for competitive Examinations conducted by the Commission.
c) The syllabus for the subject papers (Paper-I) and “General Studies” (Paper-II) are available
in Annexure-IV to this Notification.
9. SELECTION PROCEDURE:
Selection will be made in two successive stages i.e., (i) Written Examination and (ii) Oral
Test in the shape of an interview. The final selection will be made on the basis of the total marks
obtained by the applicants at the written examination and oral test taken together subject to the
rule of reservation of appointments. Applicants‟ appearance in the written examination and oral
test is compulsory. The applicant who has not appeared for any of the subjects in the written
examination will not be considered for selection even if he/she secures the minimum qualifying
marks for selection.
(For further details refer to para. 23 (b) of the“Instructions to Applicants”)
Note:
(i) Request for change of examination centre / venue will not be entertained (For further
details refer to the “Instructions to Applicants”).
(ii) The Commission reserves the right to increase or decrease the number of examination
centres and to re-allot the applicants accordingly.
(iii) Applicants should appear for the written examinations / certificate verification / oral test
at their own expenses.
(I) Wherever vacancies are reserved for Arunthathiyars on preferential basis, even after filling
the vacancies reserved for SC (Arunthathiyars) on preferential basis, if more number of
qualified Arunthathiyars are available, they shall be entitled to compete with the Scheduled
Castes other than Arunthathiyars in the inter-se-merit among them and if any posts
reserved for Arunthathiyars remain unfilled for want of adequate number of qualified
applicants, it shall be filled by Scheduled Castes other than Arunthathiyars.
(Section 27 of the Tamil Nadu Government Servants (Conditions of Service) Act, 2016).
(J) Any claim made after the submission of online application will not be entertained.
Evidence for all the claims made in the online application should be uploaded / submitted
in time when the same are called for. Failure to upload / submit the documents within the
stipulated time limit will entail rejection of application.
(K) Correct and true information regarding arrest, convictions, criminal or any disciplinary
proceedings initiated / pending or finalised, debarment / disqualification by any recruiting
agency, participation in agitation or any political organisation, candidature in election
for Parliament / State Legislature / Local Bodies etc, if any, should also be furnished to the
Commission at the time of application. The details thereof, i.e. originals of the judgement /
order / G.O. dropping further action in the departmental proceedings or any document that
may prove the suitability of such applicants for appointment in such cases must be
produced at the stage / time of certificate verification without fail. All such events that
occur after the submission of application and till the date of his / her selection and
appointment shall be reported to the Commission forthwith. Failure to report on the part of
the applicant will be considered as suppression of material information and will attract
suitable penal action.
(L) Incomplete applications and applications containing wrong claims or incorrect particulars
relating to category of reservation / eligibility / age / communal category / educational
qualification / medium of instruction / physical qualification / other basic qualifications and
other basic eligibility criteria will be liable for rejection.
(M) One Time Registration is not an application for any post / recruitment. Though the details
/ particulars have already been furnished by the applicants under One Time Registration
system, the claims made in the online application for this recruitment alone will be
taken into consideration. The Commission will not be responsible for any consequences
arising out of furnishing of incorrect and incomplete details in the application or omission to
provide the required details in the application for this recruitment.
(N) Refer Annexure-III of this notification regarding determination of community and
reservation in employment for third gender.
c) Grievance Redressal Cell for guidance of applicants: In case of any guidance / information /
clarification regarding applications, candidature, etc., applicants can contact the
Commission‟s office in person or over Telephone No. 044-25332833 / 25332855 or the
Commission‟s Toll-Free No. 1800 425 1002 on all working days between 10.00 a.m. and
05.45 p.m. or Commission‟s e-mail id [email protected].
d) COMMUNICATION TO APPLICANTS:
Individual communication regarding the date and time of certificate verification, oral test
and counselling (as applicable) will not be sent to the applicants by post. The details will be
made available on the Commission’s website. Applicants will be informed of the above fact
only through SMS and e-mail and they should watch the Commission’s website in this
regard.
e) After notification, during the process of recruitment till publication of result, no
information under Right to Information Act would be furnished.
17. WARNING
All recruitments by the Tamil Nadu Public Service Commission are purely merit based.
Tamil Nadu Public Service Commission hereby cautions the candidates against touts and
agents cheating by making false promises of securing job through unfair means.
Tamil Nadu Public Service Commission shall not be responsible or liable for any loss that
may be caused to any candidate on account of indulging in any sort of actions with such
unscrupulous elements.
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14
DISCLAIMER
Secretary
15
ANNEXURE- I
ANNEXURE-II
EXPERIENCE CERTIFICATE
10. Certificate from the Institution / Organisation The above said employee having
experience in this Institution /
: Organisation as stated above.
The above particulars furnished
by us are correct
Office seal:
Date:
Place:
Signature
Note:
Institution / Organisation which issues the certificate is cautioned that issuing of any certificate
containing false details will lead to legal / penal action on them.
17
ANNEXURE-III
I
18
19
20
ANNEXURE-IV
l) Quality control of the following formulations: Semisolids, Solid dosage forms, Liquid
dosage forms, Parenteral and ophthalmic preparations.
m) New Drug Delivery Systems- Aerosols, Ocusert, Transdermal Drug Delivery
Systems, Osmotic Drug Delivery Systems, Targeted Drug Delivery Systems,
Prolonged Drug Delivery Systems.
n) Cosmetics- Dentifrices, Lipsticks, Face powders, shampoos, depilatories and
Manicure preparations.
UNIT- II:
a) Blood Products and Plasma Substitutes: Collection, processing and storage of
whole human blood, concentrated human RBCs, dried human plasma, human
fibrinogen, human thrombin, human normal immunoglobulin, human fibrin foam,
plasma substitutes, ideal requirements of PVP, dextran, etc. Control of blood
products as per IP.
b) Basics of pharmacokinetic studies and their importance
c) Pharmaceutical Biotechnology- General principles of immunology, immunological
techniques used in pharmacy; Sterilization of different pharmaceutical dosage
forms; Sterility Testing; Methods of preparation of official sera and vaccines;
Microbiological assays of antibiotics and vitamins of the pharmacopeia;
Disinfectants- Classification, Mechanism and uses of disinfectants in brief. Factors
affecting disinfection and methods of disinfectant evaluation.
d) Immunologicals: Preparation and quality control of products representing
various categories like
Toxoids – Diphtheria and Tetanus Live
Bacterial Vaccines – BCG
Killed Bacterial Vaccines – Cholera, DPT
Viral Vaccines – Polio, Rabies and small pox
Antitoxins – Diphtheria
UNIT – III:
a) Chemistry of Alkaloids, Vitamins, Flavanoids, Glycosides, steroids, terpenes,
vitamins and hormones.
b) Catalytic hydrogenation, dehydrogenation, metal hydride reduction. Reduction
with hydrazine and its derivatives, Birch reduction, Clemenson‟s reduction,
Meerwin – Ponndrof reduction, oxidation with periodic acid, lead tetra acetate,
22
Synthesis, properties, test for purity, storage of the following categories of drugs -
Analgesics and Antipyretics, Anti-inflammatory, Hypnotics and sedatives, Anti
convulsants, Anti-psychotics, Anti-histamines, Sympathomimetics, Adrenergic
antagonists, Cholinomimetics and anti-cholinergic, Local Anaethetics, Anti-
hypertensives, Anti-anginal, Sulphonamides,antibiotics, Anti-TB, Anti-Viral, Anti-
Fungal, Antimalarials, Anti-Neoplastics.
UNIT- V:
a) Principles and Pharmacopeial Assay Procedures involving Non-aqueous Titration,
Oxidation-Reduction, Diazotization, complexometric methods, electrometric
titration, gravimetric analysis.
b) Polarimetry and refractometry, and gasometric analysis of oils, fats and waxes.
c) Chromatography- TLC, Column, Paper, GC, Ion exchange, HPLC, HPTLC, Gel
electrophoresis.
d) Theory, principle, instruments and applications of colorimetry, UV- Visible
Spectrometry, Fluorimetry, Nephalometry, Turbidometry, IR, Mass, NMR, RIA.
UNIT- VI:
a. General Pharmacology:- Routes of adminstration, Absorption, distribution,
Biotransformation and Extretion of drugs, Bioavailability and bio equivalence, Factors
affecting bioavaliability, Mechanism of action of drugs at receptor level, adverse drug
reaction.
b. Drugs acting on Central Nervous system: Analgesics, Nonsteroidal anti inflammatory
drugs, Sedatives and Hypnotic, Anti convulsants and Antipsychotic drugs. Drugs used
in parkinsonism.
c. Drugs acting on Autonomic Nervous system: Drugs which influence the working of
autonomic nervous system, Adrencrgic drugs (or) sympathominitic drugs, Adrenergic
blocking drugs, Cholinergic drugs and cholinergic blocking drugs, Drugs acting on
autonomic ganglia.
d. Drug acting on cardiovasular system: cardiac glycosides, Anti hypertensive, anti
arrhythmic and anti anginal drugs.
e. Diuretics & anti diuretics.
23
UNIT- VII:
a. Drugs acting on GIT.
b. Insulin and oral anti diabetic drugs, Thyroid and anti-thyroidal drugs, oral
contraceptives. Hormone replacement therapy, drugs acting on uterus.
c. Antihistaminic drugs and Drugs used in Migraine.
d. Chemotherapy- sulphonamides penicillins, cephalosporins, quinolones, Tetracyclines,
Aminoglycosides, Chemotherapy of Tuberculosis, leprosy, malaria, cancer ,
Ameobiasis, Helminthiasis.
e. Toxicology- Systematic & local treatment of poisoning and their treatment.
UNIT- VIII:
a. General principles of cultivation and collection of drugs from wild & cultivated sources,
their merits and demerits, factors affecting cultivation, adulterants and their detection.
b. Plant growth regulators.
c. Source, synonym, cultivation, collection, preparation for market, diagnostic characters
(both macroscopical and microscopical). Constituents, substitutents, adulterants and
uses of Cinnamon, Cinchona, Senna, digitalis, Clove, Saffron, Pyrethrum. Cochineal,
Ergot, opium, Aloe, Acacia, Tragacanth, Benzoin, Ginseng, Brahmi, Dioscorea,
Cascara, Gelatin, umbelliforous fruits, spirulina, nuxvomica, ginseng, belladonna,
taxol , vinca.
d. Principle and application plant tissue culture.
e. Basics of fermentation technology & production of Antibiotics, Vitamins.
UNIT- IX:
a. Biosythetic pathways of Tropane alkaloids, Cholesterol, amino acids.
b. WHO Guidelines for herbal medicines.
UNIT- X:
a. Drugs and Cosmetics Act 1940 and Rules 1945.
b. Pharmacy Act 1948.
--------
24
PAPER - I
SUBJECT PAPER: CLINICAL PHARMACOLOGY
(POST GRADUATE DEGREE STANDARD)
Objective Type
PAPER - I
SUBJECT CODE:351
1 Staphylococcus
2 Streptococcus
3 Neisseria
4 Coryne bacteria
27
5 Bacillus
6 Mycobacteria
7 Actinomyecetes & Nocardia
8 Coliform bacteria-Escherichia coli & kelsiella 9 Proteus
9 Salmonella
10 Shigella
11 Yersinia
12 Pasteurella & Francisella
13 Haemophilus
14 Bordetella
15 Brucella
16 V. Cholerae
17 Pseudomonas
18 Spirochetes
19 Rickettsiae
20 Chlamydia
21 Mycoplasma
22 Miscellaneous Bacteria
UNIT - IV PARASITOLOGY
1 Classification
2 General principles of Diagnosing parasites & treatment of parasitic infection.
3 Protozology
Pathogenic and Non-pathogenic amoebae and free living amoebae
Intestinal, Blood & Tissue flagellates Plasmodium, Toxoplasma, Isospora
4 Balantidium coli
5 Helminthology
Cestodes, Trematodes, Nematodes
1 Classification of viruses
2 Replication of Viruses
3 Cultivation of Viruses
4 Identification of Viruses & Lab diagnosis
5 Pathogenesis & Host response to Viral infection
6 Bacteriophage
7 Antiviral Agents
8 Viral Vaccines
1 Pox
2 Adeno
3 Herpes
28
4 Papova
5 Parvo
6 Picorna
7 Orthomyxo
8 Paramyxo
9 Rota virus
10 Rhabdovirus
11 Hepatitis
12 Arbo
13 Retro
14 Slow-viruses
15 Oncogenic virus
16 Miscellaneous
virus
UNIT - VII Mycology
1 Classification of fungi
2 Fungal Mycotoxins
3 Pathogenesis & Lab diagnosis of Mycotic infections
4 Superficial Mycosis
5 Cutaneous Mycosis
6 Subcutaneous Mycosis
7 Systematic Mycosis
8 Opportunistic Mycosis and common lab contaminants
9 Antifungal Agents
1 C.N.S infection
2 Respiratory Infections
3 Urinary Tract Infection
4 Gastro intestinal Infection
5 Genital Tract Infection
6 Congenital Infection
7 Infections of Eye, Ear & Skin
8 Infections of Cardiovascular System
9 P.U.O
10 Zoonotic Infections
*******
30
PAPER – I
SUBJECT PAPER: PHARMACEUTICAL CHEMISTRY (DEGREE STANDARD)
Objective Type
SUBJECT CODE.245
UNIT I
UNIT II
1) Assay, test for purity of sodium, calcium, iron, aluminium and ammonium
compounds. Major intracellular and extra cellular electrolytes.
2) Preparation and use of Chemical reagents and Volumetric Solutions as per
Pharmacopia in Pharmaceutical Analysis.
3) Theory of Co-ordination Compounds with special reference to application in
Pharmaceutical Analysis via EDTA, Dimercaprol, Pencillamine.
UNIT III
UNIT IV
1) Gases in liquids, liquids in liquids, partially miscible, completely miscible and
completely immiscible liquids.
2) Thermochemistry: Heat of reaction, heat of solution, heat of formation and heat
of neutralization and Hess law.
3) Stereo chemistry, optical isomerism, Geometrical isomerism.
4) Theory of Polarimetry, Refractometry and catalyst.
UNIT V
1) Electronic configuration and electron displacement effects, chemical bonds and
polarity.
2) Chemistry and medicinal uses of cardiac glycosides and vitamins.
3) Synthetic utility of acetoacetic ester, Grignard reagent and
Diazonium compounds.
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UNIT VI
1) Aromaticity,concept of resonance, Nucleophilic, Electrophilic
substitution reaction, Elimination reactions in aliphatic and aromatic
compounds.
2) Anti-infective agents comprising of Anti-fungal agents, synthetic antibacterial
agents, anti-tubercular Agents, and Anthelmintics agents.
UNIT VII
Chemical structure, Synthesis, assay and therapeutic uses of organic synthetic drugs
like, Antidepressants, General anesthetics, Sedatives and hypnotics, Narcotic
analgesics, Anti -histaminics, Antimalarials., Sulphonamides, Drugs acting on CVS.
UNIT VIII
1) Structural elucidation of natural products - General methods.
2) Structure, chemistry, methods of estimation, and uses of Alkaloids, Carbohydrates,
and Proteins.
3) Chemistry of steroids and natural hormones, currently used steroidal drugs.
UNIT IX
PAPER – I
SUBJECT PAPER: CHEMISTRY (DEGREE STANDARD)
Objective Type
SUBJECT CODE.243
UNIT - I
PHYSICAL CHEMISTRY:-
a) Gas law and Kinetic Theory:- Ideal gas equation - Deviation from ideal behaviour -
vander waals equation for real gases - Molecular velocities - the Maxwell's distribution
of molecular velocities –heat capacity and viscosity of gases.
b) Solid State:- Crystal systems - Bravaislattice - Unit Cell - Miller Indices - Symmetry
elements in crystals - Bragg's equation - Radius ratio's and packing in crystals –
Determination of crystal structures by Braggs method – structure of Nacl, Kcl, Zns
and spinals.
UNIT – II
d) Chemical Kinetics:- Rate laws - rate constant - order and molecularity of reactions
I, II, III, and Zero order reaction Arrhenius theory - collision theory and Transition state
theory - catalysis.
e) Electro-Chemistry:- Types of reversible electrodes - Nernst equation - reference
electrode and standard hydrogen electrode - computation of cell e.m.f. calculations of
thermodynamic quantities of cell reactions (DG, DH, DS and K) - Over potential and
hydrogen over voltage - Arrhenius theory - Debye 'Huckel equation - Kohliraush's law
- Ostwald's dilution law - Determination of PH and Pka of acids by potentiometric
methods.
UNIT – III
UNIT - IV
h) Colloids and surface Chemistry:- Classification – preparation, purification -
properties - Tyndall effect- Gels - Emulsions Absorption - Langmuir isotherms -
Heterogeneous catalysis.
i) Physical properties and Chemical constitution:- Surface tension - parachor and its
application to structural problems – Dipole moment - applications of dipolemoment
measurements to structural studies of simple inorganic and organic molecules -
magnetic properties of matter, diamagnetism, paramagnetism, ferromagnetism and
anti- ferromagnetism - Applications to structural problems.
UNIT - V
INORGANIC CHEMISTRY:-
k) Chemical bond:- Lattice energy - VSEPR Theory and its applications - partial ionic
character from electronegativity - Fajan's Rules.
l) Compounds of Boron:- Electron deficient nature of boron compounds -
preparation and properties of halides and nitrates of boron - diborane – Borazine,
silicones and structures of silicates
UNIT - VI
UNIT - VII
p) Co-ordination Chemistry:- Redo Nomenclature - theories of co-ordination
compounds - Werner, valence bond, crystal field and ligand field theories - Effective
atomic number - isomerism - Metal Carbonyls of iron and Nickel.
UNIT - VIII
ORGANIC CHEMISTRY:-
r) Types of reactions:- Nucleophilic, electrophilic, free radicals, addition and
elimination reactions.
s) Electron displacement effects:- Inductive, inductometric, electromeric, mesomeric,
resonance, hyperconjugation and steric effects.
UNIT - IX
t) Nature of Bonding:- Hybridisation (Sp, Sp2 & Sp3) and Geometry of molecule -
cleavage of bonds - homolytic and heterolytic fission of carbon – carbon bonds -
Reaction intermediates - free radicals, carbocations and carbonions - their stability.
UNIT - X
PAPER-II
GENERAL STUDIES (DEGREE STANDARD)
Objective Type
SUBJECT CODE : 003
UNIT-III : GEOGRAPHY
Earth and Universe - Solar system-Atmosphere hydrosphere, lithosphere - Monsoon, rainfall,
weather and climate - Water resources - rivers in India-Soil, minerals & natural resources - Natural
vegetation - Forest & wildlife-Agricultural pattern, livestock & fisheries -Transport including
Surface transport & communication - Social geography – population -density and distribution-
Natural calamities – disaster management-Climate change - impact and consequences -
mitigation measures - Pollution Control.
36
ANNEXURE - V
Secretary