Batimentos Cardiacos e Arritimia
Batimentos Cardiacos e Arritimia
Batimentos Cardiacos e Arritimia
to Irregular Heartbeat:
Results of a Randomized,
Double-Blind
Placebo-Controlled Study
MR Publishing
Table of Contents
PART 1: What you should know about the heartbeat
and arrhythmia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .5
A. How heart rhythm is regulated . . . . . . . . . . . . . . . . . . . . .5
B. Why conventional medicine has failed in
solving arrhythmia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .7
60-70
C. The Cellular Health breakthrough in
understanding arrhythmia . . . . . . . . . . . . . . . . . . . . . . . . .8
PART 2: Importance of clinical research . . . . . . . . . . . . . . . . . . . . .11
A. What is a randomized, double-blind
placebo-controlled study? . . . . . . . . . . . . . . . . . . . . . . .11
In an adult person, the heart beats B. How efficacy of the treatment is determined (p-value) . .12
C. Why it is important to have many centers involved . . . . .12
approximately 60-70 times per minute...
PART 3: Objective of the study . . . . . . . . . . . . . . . . . . . . . . . . . . . .15
3>
PART 4: Description of patients, treatment, and study duration .17
A. Treatment . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .18
PART 5: Results . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .21
A. The Cellular Health vitamin program decreases
arrhythmic episodes . . . . . . . . . . . . . . . . . . . . . . . . . . . .21
B. The Cellular Health vitamin program helps
patients become free of arrhythmia . . . . . . . . . . . . . . . .22
C. Health improvements with longer use of the
Cellular Health vitamin program . . . . . . . . . . . . . . . . . . .23
D. The Cellular Health vitamin program has positive
effects on general well-being and other health aspects .26
PART 6: Conclusions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .29
PART 7: About Matthias Rath, M.D. and
Aleksandra Niedzwiecki, Ph.D. . . . . . . . . . . . . . . . . . . . 33
PART 8: Acknowledgments . . . . . . . . . . . . . . . . . . . . . . . . . . . . .35
PART 9: Literature . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .35
PART 1:
25 Million
The human heart beats approximately
25 million times during a lifetime.
If you have experienced palpitations, rapid heartbeat, dizziness
and shortness of breath, it is likely that you have developed an
irregular heartbeat, also called arrhythmia. Millions of people suf-
fer from this condition, which most often occurs in people
between the ages of 50-70. Approximately 30%-60% of individu-
5>
als in this age group suffers from some form of arrhythmia at one
point in their lives.
aimed at maintaining regular and timely contraction and relaxation Tachycardias – frequent heartbeat
of the entire heart muscle. There are specific groups of heart cells (more than 100 beats per minute)
that generate and conduct the electrical impulses for the regular
Brachycardias – slow heartbeat
heartbeat. These cells form two bulks (the sinus node and the AV
(less than 60 beats per minute)
node), which function like biological batteries. (See Figure 1.) They
generate the energy for the heartbeat that assures the coordinat- Arrhythmias – irregular frequency of heartbeat
ed and rhythmical contractions of the entire heart muscle.
Arrhythmias
Normal
heartbeat
Figure 2.
<6 7>
tant and frequent of these side effects are the generation of even an optimum supply of
more irregular heartbeats and, not infrequently, cessation of the energy-generating
heartbeat (sudden cardiac death). nutrients, convention-
al medicine has relied
on mechanical
C. THE CELLULAR HEALTH BREAKTHROUGH IN
devices and pharma-
UNDERSTANDING ARRHYTHMIA
ceutical drugs that
The Cellular Health approach to arrhythmia differs substantially have severe side
from the conventional medical approach1. This new understanding effects. A 10-year-old
about the basis of health and diseases developed by Matthias child can understand
Rath, M.D. investigates the underlying causes of diseases by ana- that a flashlight can-
lyzing the function and nutritional needs of the body’s cells. not operate without
“physical” electricity
In order to generate electricity, the “electrical” cells of the heart from batteries. In the
need large amounts of bio-energy. Therefore, they require a con- same way, doctors
<8 9>
stant supply of nutrients (bio-catalysts), which are essential for the and patients must
conversion of food into cellular energy. The most critical among accept the fact that
these nutrients are coenzyme Q-10, carnitine, the B vitamins, lysine the cellular electrical
and vitamin C, along with magnesium, calcium, and potassium. impulses needed for
the heartbeat require
Causes, prevention and treatment of irregular heartbeat
For optimum biological effect, the nutrients must complement and a continuous supply
support each other in synergy. They provide basic biological fuel of “biological” energy.
for optimum function of all cells, but particularly for the electrical
cells of the heart, which have extraordinary nutritional demands. If Cellular Health takes advantage of this logical approach. It has
we do not provide our bodies with optimum amounts of these defined a nutrient program that has already improved irregular
micronutrients, the heart cells will fail to properly generate and heartbeat conditions in thousands of patients (www.dr-rath-
conduct electrical impulses. An irregular heartbeat will develop as research.org). In order to provide definite scientific proof about
a result. the effectiveness of this program, we conducted a clinical study
with the objective of providing indisputable evidence about the
It cannot be easily explained why conventional medicine has over- efficacy of the Cellular Health approach in patients suffering from
looked this simple fact. Instead of ensuring that the heart receives arrhythmia.
PART 2:
Importance of
clinical research
In order to assess objectively whether the Cellular Health
energy and
Potassium is an important nutrient
needed for generating cellular energy
and coordinating heart rhythm. For
approach works, we have conducted a clinical study with a defined
Cellular Health vitamin program in a large population of patients.
It is important that everyone understand what a clinical study is
and its implications.
transmitting
11>
maintaining regular heatbeat, potassium A. WHAT IS A RANDOMIZED, DOUBLE-BLIND
must stay in balance with sodium and PLACEBO-CONTROLLED STUDY?
other minerals. The highest standard of clinical assessment regarding the efficacy
of any treatment is a randomized, double-blind placebo-controlled
study. The individual terms are explained as follows:
Coenzyme
<12 equal to 0.05 (p<0.05) confirms that the studied event can occur.
If the p-value is lower than 0.05, the significance of the conclu- Coenzyme Q10 is an important molecule
sions is higher. needed for the optimum production of
cellular energy, and should be supplemented
In general, the lower the p-value is, the stronger the validity of the
with vitamin B2, niacin and other essential
Q10
results.
nutrients.
C. WHY IT IS IMPORTANT TO HAVE MANY
CENTERS INVOLVED Cellular health utilizes nutrient synergy
Each of us is different, and many factors can contribute to the out- for maximum health benefits.
come of the treatment. Therefore, by testing the Cellular Health
vitamin program on a diverse population of patients, we could
reinforce the validity of the results.
Objective of
the study
irregular
Vitamin C and Lysine are essential nutrients
for the production of carnitine. Vitamin C
and lysine are not produced in our bodies,
The purpose of the study was to examine whether the long-term
intake of vitamins and other essential nutrients, in addition to a
conventional basic therapy, would lead to a reduction in the
number of clinically apparent arrhythmic episodes in patients
heartbeat
with arrhythmia.
and a deficiency of these nutrients leads to 15>
Description of
patients, treatment,
and study duration
5.25 feet -
The electrical impulses that synchronize
the rhythmic contractions of the heart are
The study involved 140 patients diagnosed with irregular heartbeat
(medical term: paroxysmal atrial arrhythmia).
per second
transmitted through cardiac muscle fibers
at the rate of 5 .25 feet per second.
Age (average)
Males
Females
Body Weight
Vitamin Group
(69 patients)
58 years old
38%
62%
Placebo Group
(71 patients)
56 years old
42%
58%
The evaluation at the end of the study revealed that among all Adjunct Vitamin Program
patients participating in the trial, 90 strictly adhered to the study
Coenzymes and Other
protocol. They did not miss visits and followed the vitamin pro- Vitamins Minerals Amino Acids Nutrients
gram for 6 months. There were 44 patients in the vitamin group
Vitamin C 700 Calcium 13 mg Taurine 200 mg Coenzyme Q-1 20 mg
and 46 patients in the placebo group who fulfilled the criteria.
Therefore, in order to be completely sure that the observed health Vitamin E 70 IU L-Carnitine 160 mg Biotin 130 mcg Vitamin B1 15 mg
effects were due to vitamin intake and not other factors, the final
Pantothenic
results were evaluated in this group of patients. Acid 40 mg
Vitamin B2 15 mg
A. TREATMENT
Niacin 30 mg
Treatment involved daily administration of Dr. Rath’s Cellular
Health vitamin program (basic and adjunct) for a six-month period: Vitamin B6 4 mg
PART 5:
Results
A. THE CELLULAR HEALTH VITAMIN PROGRAM
DECREASES ARRHYTHMIC EPISODES
Figure 3.
frequent episodes of irregular heartbeat taking the placebo and The results presented in Figure 4 show that 93.5% of patients
the number of patients taking the vitamins. assigned to a placebo group were still suffering from arrhythmia
after six (6) months, despite taking anti-arrhythmic medication dur-
The results in Figure 3 indicate that the majority of patients ing that time. This indicates that pharmaceutical drugs are ineffec-
(approximately 73.9%) who suffered from arrhythmia had taken the tive in the majority of patients suffering from this condition.
placebo. However, in the vitamin group, remarkably fewer patients However, in the group taking the vitamins, significantly fewer
reported having arrhythmia (47.8%). This means that approximately patients experienced irregular heartbeat (84.1%). Therefore, with
1/3 of patients experienced considerable relief from frequent irreg- the use of vitamins, the likelihood of being free from arrhythmia
ular heartbeats following the Cellular Health vitamin program. This doubled (15.9% in the vitamin group vs. 6.5% in the placebo
result was statistically significant based on the p-value of 0.01, group).
which means that there is a very high probability that this result
could be repeated in other patients. The results were statistically significant, and the p-value of less
than 0.01 indicated that it is highly probable that other persons
CONCLUSION: could experience these results.
The study indicates that Dr. Rath’s Cellular Health vitamin
<22 23>
program can decrease frequent arrhythmia episodes in 30% CONCLUSION:
of patients after six (6) months. The results clearly show that by using Dr. Rath’s Cellular Health
vitamin program, the likelihood of being free of irregular
B. THE CELLULAR HEALTH VITAMIN PROGRAM heartbeat more than doubles.
HELPS PATIENTS BECOME FREE OF ARRHYTHMIA
Figure 4.
beneficial effects of nutrients after a few weeks of their intake, and
The Cellular Health Solution to Irregular Heartbeat PART 5: Results
health improvements continue with longer use of the vitamin pro- advanced stages of the disease can expect improvements in
gram. Therefore, we have determined that there are benefits in their heart conditions.
the long-term use of the Cellular Health vitamin program for
arrhythmia. • More people are completely free from arrhythmia with longer
use of the Cellular Health vitamin program.
• Frequency of arrhythmia attacks decreases with longer use of
the Cellular Health vitamin program.
77.3%
75%
Number of people with frequent
arrhythmia
45.5%
(in %)
50%
56.7%
(in %)
50%
27.3%
25%
These results confirm the health benefits of long-term vitamin use. health and a gradual diminishing of their quality of life. To a large
The observed trend also suggests that by continuous adherence extent, this is associated with drug side effects and the realization
to the Cellular Health vitamin program, many more patients can that a cure for this health problem is not available.
be arrhythmia free. This also confirms that, due to vitamin intake,
approximately 70% of study participants experienced an improve- Our study took this important aspect into account, and we evalu-
ment in their health conditions. ated how vitamin intake affected patients’ general well-being and
quality of life. The results were compiled using a standardized
CONCLUSION: quality of life assessment questionnaire, which is used in all types
This remarkable result confirms that the longer vitamins are of human studies. The questionnaire used in our study evaluated
used, the better one’s health becomes! 36 different parameters that described the physical function of
patients, level of pain, emotional status, vitality, perception of
D. THE CELLULAR HEALTH VITAMIN PROGRAM HAS general health and other aspects.
POSITIVE EFFECTS ON GENERAL WELL-BEING
AND OTHER HEALTH ASPECTS The results of this questionnaire were analyzed by a computer
based on a grading system assigned to each question that
<26 27>
allowed for quantitative comparison of the results. The assessment
of quality of life in our study was very encouraging for vitamin
users. Patients who took Dr. Rath’s Cellular Health vitamin pro-
gram scored almost twice as high on a quality of life assessment
questionnaire than patients who took the placebo.
Conclusions
The results of this randomized, double-blind placebo-controlled
study conclusively document the effectiveness of vitamins and
arrhythmia and
Patients taking anti-depressants, certain
antibiotics, cardiac medications or
other essential nutrients in controlling irregular heartbeat, a condi-
tion for which conventional medicine does not provide a solution.
even cardiac
tamoxifen are at risk of arrhythmia
and even cardiac death.
These health benefits were achieved by addressing the underlying
cause of arrhythmia, which is the deficiency of nutrients that gen- 29>
death
Hennessy S et al in British Medical Journal 2002, 325, 1070
Curtis LH et al in American Journal of Medicine 2003, 114, 135 - 141)
erate bio-energy in the heart muscle cells. The Cellular Health vita-
min program used in the study provided nutrients in the right
composition and proportion, which helped achieve the following
benefits within six (6) months:
Dr. Rath’s clinical research proves that the cause of most common
diseases is actually long-term nutrient deficiencies and his Cellular
Health approach defines optimum nutrition for the body’s cells as
a means to prevent and control today’s most common diseases.
He established Dr. Rath’s Health Alliance so that people every-
where can take advantage of his scientific discoveries in Cellular
Health and participate in the battle for vitamin freedom.
Literature
1. M. Rath. Why Animals Don’t Get Heart Attacks, But People Do,
MR Publishing, Inc. 2001.