MC Hydroxyzine

Medication Card
Generic name of medication Brand/trade name of medication
hydroxyzine, TAB Atarax
Drug classification (i.e. beta blocker, etc) 1. Patient dose

10mg, oral
Ther. Class. 2. Safe dose ranges
antianxiety agents
antihistamines PO: (Adults) Antianxiety– 25–100 mg 4
sedative/hypnotics times/day, not to exceed 600 mg/day.
Preoperative sedation– 50–100 mg single
dose. Antipruritic– 25 mg 3–4 times daily.
PO: Children –2 mg/kg/day divided every

6–8 hr.
IM: (Adults) Preoperative sedation– 25–

100 mg single dose. Antiemetic, adjunct to
opioid analgesics– 25–100 mg every 4–6 hr
as needed.
IM: Children –0.5–1 mg/kg every 4–6 hr as

needed.
3. Is the dose safe

Yes
Therapeutic effect (i.e. decreased heart rate, Indication in this patient

etc) and when it should develop
Anxiety
 Acts as a CNS depressant at the
subcortical level of the CNS.
 Has anticholinergic, antihistaminic, and
antiemetic properties.
 Blocks histamine 1 receptors.
Therapeutic Effect(s):
 Sedation.
 Relief of anxiety.
 Decreased nausea and vomiting.
 Decreased allergic symptoms
associated with release of histamine,
including pruritus.
Pre and post administration assessment Unique nursing considerations
 Assess patient for profound sedation Contraindicated in:

and provide safety precautions as
indicated (side rails up, bed in low  Hypersensitivity;
position, call bell within reach,  QT interval prolongation;
supervision of ambulation and transfer).  OB: Potential for congenital defects
Geri: Older adults are more sensitive to (oral clefts and hypoplasia of cerebral
CNS and anticholinergic effects hemisphere;
(delirium, acute confusion, dizziness,  Lactation: Safety not established.
dry mouth, blurred vision, urinary
retention, constipation, tachycardia). Use Cautiously in:
Monitor for drowsiness, agitation, over
sedation, and other systemic side  Severe hepatic impairment;
effects. Assess falls risk and implement  Congenital long QT syndrome,
prevention strategies. family history of long QT syndrome,
 Anxiety: Assess mental status recent MI, HF, hypokalemia,
(orientation, mood, and behavior). hypomagnesemia, bradycardia, or
 Nausea and Vomiting: Assess degree concurrent use of antiarrhythmics;
of nausea and frequency and amount of  Concurrent use of medications that
emesis. cause QT interval prolongation;
 Pruritus: Assess degree of itching and  OB: Has been used safely during
character of involved skin. labor;
 Pedi: Injection contains benzyl
Lab Test Considerations: alcohol, which can cause potentially
fatal gasping syndrome in neonates;
May cause false-negative skin test results using  Geri: Appears on Beers list . Older
allergen extracts. Discontinue hydroxyzine at adults are more susceptible to adverse
least 72 hr before test. reactions due to anticholinergic
effects; dose ↓ recommended.
Adverse effects/minimizing discomfort and Key patient teaching points

harm
CNS: drowsiness, agitation, ataxia, dizziness,  Instruct patient to take medication
headache, weakness exactly as directed. Missed doses
should be taken as soon as
CV: TORSADE DE POINTES, QT interval remembered unless it is almost time
prolongation for next dose; do not double doses.
 May cause drowsiness or dizziness.
Resp: wheezing Caution patient to avoid driving and
other activities requiring alertness
GI: dry mouth, bitter taste, constipation, until response to medication is
nausea known. Geri: Warn patients or
caregivers that older adults are at
GU: urinary retention increased risk for CNS effects and
falls.
Derm: acute generalized exanthematous  Advise patient to avoid concurrent
pustulosis, flushing, rash use of alcohol or other CNS
depressants with this medication.
Local: pain at IM site, abscesses at IM sites  Inform patient that frequent mouth
rinses, good oral hygiene, and
Misc: chest tightness sugarless gum or candy may help
decrease dry mouth. If dry mouth
* CAPITALS indicate life-threatening. persists for more than 2 wk, consult
Underline indicate most frequent. dentist about saliva substitute.
 Advise female patient to notify health
care professional if pregnancy is
planned or suspected or if breast
feeding.

MC Hydroxyzine

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Medication Card

Generic name of medication Brand/trade name of medication

hydroxyzine, TAB Atarax

Drug classification (i.e. beta blocker, etc) 1. Patient dose

PO: Children –2 mg/kg/day divided every

IM: (Adults) Preoperative sedation– 25–

IM: Children –0.5–1 mg/kg every 4–6 hr as

3. Is the dose safe

Therapeutic effect (i.e. decreased heart rate, Indication in this patient

Pre and post administration assessment Unique nursing considerations

 Assess patient for profound sedation Contraindicated in:

Adverse effects/minimizing discomfort and Key patient teaching points

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