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    Pathophysiology of Bipolar 1 Disorder

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    myer pasandalan
    Bipolar 1 disorder is influenced by genetic, environmental, biological, and neurological factors. Genetically, it has the strongest familial link when first-degree relatives are affected. Biologically, it may involve imbalances of neurotransmitters like norepinephrine and serotonin. Neurologically, abnormalities have been found in the white matter of the brain. Signs and symptoms include manic phases with elevated mood and rapid speech, and depressive phases with low mood, loss of interest, and suicidal thoughts. Complications include suicide, violence, and other psychiatric disorders. Treatment combines psychotherapy, psychoeducation, mood stabilizers, and antipsychotics.

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    Pathophysiology of Bipolar 1 Disorder

    Uploaded by

    myer pasandalan
    286 views1 page
    Bipolar 1 disorder is influenced by genetic, environmental, biological, and neurological factors. Genetically, it has the strongest familial link when first-degree relatives are affected. Biologically, it may involve imbalances of neurotransmitters like norepinephrine and serotonin. Neurologically, abnormalities have been found in the white matter of the brain. Signs and symptoms include manic phases with elevated mood and rapid speech, and depressive phases with low mood, loss of interest, and suicidal thoughts. Complications include suicide, violence, and other psychiatric disorders. Treatment combines psychotherapy, psychoeducation, mood stabilizers, and antipsychotics.

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    Bipolar 1 disorder is influenced by genetic, environmental, biological, and neurological factors. Genetically, it has the strongest familial link when first-degree relatives are affected. Biologically, it may involve imbalances of neurotransmitters like norepinephrine and serotonin. Neurologically, abnormalities have been found in the white matter of the brain. Signs and symptoms include manic phases with elevated mood and rapid speech, and depressive phases with low mood, loss of interest, and suicidal thoughts. Complications include suicide, violence, and other psychiatric disorders. Treatment combines psychotherapy, psychoeducation, mood stabilizers, and antipsychotics.

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    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    286 views1 page

    Pathophysiology of Bipolar 1 Disorder

    Uploaded by

    myer pasandalan
    Bipolar 1 disorder is influenced by genetic, environmental, biological, and neurological factors. Genetically, it has the strongest familial link when first-degree relatives are affected. Biologically, it may involve imbalances of neurotransmitters like norepinephrine and serotonin. Neurologically, abnormalities have been found in the white matter of the brain. Signs and symptoms include manic phases with elevated mood and rapid speech, and depressive phases with low mood, loss of interest, and suicidal thoughts. Complications include suicide, violence, and other psychiatric disorders. Treatment combines psychotherapy, psychoeducation, mood stabilizers, and antipsychotics.

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    © All Rights Reserved
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    Download as docx, pdf, or txt
    of 1

    Etiologic Factors: BIPOLAR 1 DISORDER

    -environmental factors: stress


    (financial problem)
    -low self-esteem
    -lack of support system
    Biological theories:
    -physically, emotionally stressed
    -neurochemical and neuroendocrine
    factors: biogenic amine theory’s about
    the imbalance or deficiency of
    Genetic Factors: neurotransmitters norepinephrine and Nueromatomical factors: appearance of
    Bipolar is greatest when the disorder is serotonin leading to depression; mania specific abnromalitites, or lesions in the
    present in the first-degree family resultsfrom inability to modulate white matter of the brain of people with
    members. neuronal excitation bipolar disorder.

    Signs and symptoms:


     Manic: Elevated, expensive or irritable mood; loud and rapid, clanging speech, flight
    of ideas; grandiose speech, delusion and easily distracted cognitive function,
    hyperactive, vulgar and obscene psychomotor activity.
     Depression: dysphoric, depressive, despairing mood, pessism with poverty of
    ideas and suicidal preoccupation, psychomotor agitation or retardation with feeling
    of fatigue, restlessness, thought blocking, blunted affect.
     Cyclothymiais marked by manic and depressive states yet is of sufficient intensity
    nor duration to merit diagnosis of bipolar or major depressive disorders

    Complications/ Risk for:


    -suicidal
    -violence towards others
    -disorders of eating, sexual behavior, conduct
    disorder and anxiety disorder

    Treatment:
    The most effective treatment is a combination of supportive psychotherapy,
    psycho education, and the use of mood-stabilizers (lithium carbamazepimne,
    or divalproex, ) in combination of anti-psychotic medications

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