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    Urine Drug Screening

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    Humaira Azmi
    This document provides information about drug screening cutoff levels and the length of time common drugs can be detected in urine. It outlines the initial and confirmatory cutoff levels used in workplace drug testing for marijuana, cocaine, opiates, and phencyclidine. It also lists potential agents that could cause false positive results on drug screening tests for various substances like marijuana, cocaine, opioids, phencyclidine, and amphetamines. Finally, it indicates the typical detection windows for various drugs in urine, ranging from a day for alcohol to over 30 days for regular marijuana use.

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    Urine Drug Screening

    Uploaded by

    Humaira Azmi
    212 views1 page
    This document provides information about drug screening cutoff levels and the length of time common drugs can be detected in urine. It outlines the initial and confirmatory cutoff levels used in workplace drug testing for marijuana, cocaine, opiates, and phencyclidine. It also lists potential agents that could cause false positive results on drug screening tests for various substances like marijuana, cocaine, opioids, phencyclidine, and amphetamines. Finally, it indicates the typical detection windows for various drugs in urine, ranging from a day for alcohol to over 30 days for regular marijuana use.

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    URIN NAPZA

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    This document provides information about drug screening cutoff levels and the length of time common drugs can be detected in urine. It outlines the initial and confirmatory cutoff levels used in workplace drug testing for marijuana, cocaine, opiates, and phencyclidine. It also lists potential agents that could cause false positive results on drug screening tests for various substances like marijuana, cocaine, opioids, phencyclidine, and amphetamines. Finally, it indicates the typical detection windows for various drugs in urine, ranging from a day for alcohol to over 30 days for regular marijuana use.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    212 views1 page

    Urine Drug Screening

    Uploaded by

    Humaira Azmi
    This document provides information about drug screening cutoff levels and the length of time common drugs can be detected in urine. It outlines the initial and confirmatory cutoff levels used in workplace drug testing for marijuana, cocaine, opiates, and phencyclidine. It also lists potential agents that could cause false positive results on drug screening tests for various substances like marijuana, cocaine, opioids, phencyclidine, and amphetamines. Finally, it indicates the typical detection windows for various drugs in urine, ranging from a day for alcohol to over 30 days for regular marijuana use.

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    Urine Drug Screening: Practical Guide for Clinicians1

    Federal Workplace Cutoff Values


    Substance
    Marijuana
    Cocaine metabolites
    Opiate metabolites
    Phencyclidine
    Amphetamines
    Methamphetamine

    Initial drug test


    level
    (immunoassay)
    (ng/mL)
    50
    300
    2000
    25
    1000
    Incomplete
    data

    Confirmatory
    drug test level
    (GC-MS)
    (ng/mL)
    15
    150
    2000
    25
    500
    500

    Summary of Agents Contributing to Positive Results by Immunoassay


    Substance tested via
    immunoassay
    Alcohol
    Amphetamines

    Length of Time Drugs of Abuse


    Can Be Detected in Urine
    Drug
    Alcohol
    Amphetamine
    Methamphetamine
    Barbiturate
    Short-acting
    Long-acting
    Benzodiazepine
    Short-acting (e.g., lorazepam)
    Long-acting (e.g., diazepam)
    Cocaine metabolites
    Marijuana
    Single use
    Moderate use (4 times/wk)
    Daily use
    Long-term heavy smoker
    Opioids
    Codeine
    Heroin (morphine)
    Hydromorphone
    Methadone
    Morphine
    Oxycodone
    Propoxyphene
    Phencyclidine

    24 h
    3 wk
    3d
    30 d
    2-4 d
    3d
    5-7 d
    10-15 d
    >30 d

    Cannabinoids

    Dextroamphetamine

    Opioids, opiates, and


    heroin

    Trimethobenzamide
    Trmipramine
    Benzodiazepines

    Substance tested via


    immunoassay

    Short-chain alcohols
    (isopropyl alcohol)
    Amantadine
    Benzphetamine
    Bupropion
    Chlorpromazine
    Clobenzorex
    l-Deprenyl
    Desipramine

    Ephedrine
    Fenproporex
    Isometheptene
    Isoxsuprine
    Labetalol
    MDMA
    Methamphetamine
    l-Methamphetamine
    (Vick's inhaler)
    Methylphenidate
    Phentermine
    Phenylephrine
    Phenylpropanolamine
    Promethazine
    Pseudoephedrine
    Ranitidine
    Ritodrine
    Selegiline
    Thioridazine
    Trazodone

    Time
    7-12 h
    48 h
    48 h

    48 h
    48 h
    2-4 d
    3d
    48-72 h
    2-4 d
    6-48 h
    8d

    Potential agents causing


    false-positive result

    Cocaine

    Potential agents causing


    false-positive result
    Dronabinol
    Efavirenz
    Hemp-containing foods
    NSAIDs
    PPIs
    Tolmetin
    Coca leaf tea
    Topical anesthetics
    containing cocaine
    Dextromethorphan
    Diphenhydramine
    Heroin
    Opiates
    Poppy seeds
    Quinine
    Quinolones
    Rifampin
    Verapamil and metabolites

    Phencyclidine

    TCAs

    Oxaprozin
    Sertraline

    1) Moeller KE, Lee KC, Kissack JC. Urine Drug Screening: Practical Guide for
    Clinicians. Mayo Clin Proc. 2008;83(1)66-76.
    Information compiled by Keegan Harse, PharmD Candidate. June 2008.

    Dextromethorphan
    Diphenhydramine
    Doxylamine
    Ibuprofen
    Imipramine
    Ketamine
    Meperidine
    Mesoridazine
    Thioridazine
    Tramadol
    Venlafaxine,
    O-desmethylvenlafaxine
    Carbamazepine
    Cyclobenzaprine
    Cyproheptadine
    Diphenhydramine
    Hydroxyzine
    Quetiapine

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