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    Plummer Vinson Flashcards (Incomplete

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    Ian Forde
    Plummer-Vinson syndrome is a disorder linked to long-term iron deficiency anemia that causes difficulty swallowing due to tissue growths in the throat. It mainly affects women in middle age and increases the risk of esophageal cancer. Symptoms include burning tongue, smooth red tongue, and trouble swallowing. Diagnosis involves blood tests and endoscopy. Treatment focuses on correcting the iron deficiency through dietary supplementation or dilation of throat tissues, which can improve swallowing and resolve tongue pain. Untreated, it carries risks of cancer and esophageal perforation.

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    Plummer Vinson Flashcards (Incomplete

    Uploaded by

    Ian Forde
    50 views2 pages
    Plummer-Vinson syndrome is a disorder linked to long-term iron deficiency anemia that causes difficulty swallowing due to tissue growths in the throat. It mainly affects women in middle age and increases the risk of esophageal cancer. Symptoms include burning tongue, smooth red tongue, and trouble swallowing. Diagnosis involves blood tests and endoscopy. Treatment focuses on correcting the iron deficiency through dietary supplementation or dilation of throat tissues, which can improve swallowing and resolve tongue pain. Untreated, it carries risks of cancer and esophageal perforation.

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    Plummer Vinson Flashcards (incomplete

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    Plummer-Vinson syndrome is a disorder linked to long-term iron deficiency anemia that causes difficulty swallowing due to tissue growths in the throat. It mainly affects women in middle age and increases the risk of esophageal cancer. Symptoms include burning tongue, smooth red tongue, and trouble swallowing. Diagnosis involves blood tests and endoscopy. Treatment focuses on correcting the iron deficiency through dietary supplementation or dilation of throat tissues, which can improve swallowing and resolve tongue pain. Untreated, it carries risks of cancer and esophageal perforation.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    50 views2 pages

    Plummer Vinson Flashcards (Incomplete

    Uploaded by

    Ian Forde
    Plummer-Vinson syndrome is a disorder linked to long-term iron deficiency anemia that causes difficulty swallowing due to tissue growths in the throat. It mainly affects women in middle age and increases the risk of esophageal cancer. Symptoms include burning tongue, smooth red tongue, and trouble swallowing. Diagnosis involves blood tests and endoscopy. Treatment focuses on correcting the iron deficiency through dietary supplementation or dilation of throat tissues, which can improve swallowing and resolve tongue pain. Untreated, it carries risks of cancer and esophageal perforation.

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    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    of 2

    The Plummer-Vinson syndrome, also called Paterson-Brown-Kelly syndrome or sideropenic dysphagia is a

    disorder linked to severe, long-term iron deficiency anemia, which causes swallowing difficulty (dysphagia)
    due to web-like membranes of tissue growing in the throat (esophageal webs). P-VS sufferers often
    complain of a burning sensation with the tongue and oral mucosa, and atrophy of lingual papillae produces
    a smooth, shiny red tongue dorsum. The cause of Plummer-Vinson syndrome is unknown; however,
    genetic factors and nutritional deficiencies may play a role. Women are at higher risk than men,
    particularly in middle age. In these patients, esophageal squamous cell carcinoma risk is increased;
    therefore, it is considered a premalignant process. Plummer-Vinson syndrome (atrophic glossitis,
    esophageal webs, anemia; all due to iron deficiency) is associated with Squamous cell carcinoma of the
    esophagus.

    Symptoms
    * Dysphagia (difficulty in swallowing)
    * Pain
    * Weakness
    * Odynophagia
    * Atrophic Glossitis
    Signs and tests
    Serial contrasted gastrointestinal radiography or upper gastrointestinal endoscopy may reveal
    the web in the esophagus. Blood tests show a hypochromic microcytic anemia that is consistent
    with an iron-deficiency anemia. Biopsy of involved mucosa typically reveals epithelial atrophy
    (shrinking) and varying amounts of submucosal chronic inflammation. Epithelial atypia or
    dysplasia may be present.

    The condition is associated with koilonychia, glossitis, cheilitis, and splenomegaly.


    Treatment
    Treatment is primarily aimed at correcting the iron-deficiency anemia. Patients with PlummerVinson syndrome should receive iron supplementation in their diet. This may improve dysphagia
    and pain. If not, the web can be dilated during upper endoscopy to allow normal swallowing and
    passage of food.

    Prognosis
    Patients generally respond well to treatment. Iron supplementation usually resolves the anemia,
    and corrects the glossodynia (tongue pain).
    Complications
    There is risk of perforation of the esophagus with the use of dilators for treatment. Furthermore it
    is one of the risk factors for developing squamous cell carcinoma of the oesophagus. Post Cricoid
    Prevention
    Good nutrition with adequate intake of iron may prevent this disorder.

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