Hospital Pharmacy
Hospital Pharmacy
Hospital Pharmacy
Prepared by:
Dr. Farman Ali Bozdar
Pharm-D, M.A Sociology,(MPhil)
CONTENTS
UNIT -I
Inpatient Pharmacy
1. Hospital Drug Distribution System
--------------------------------------- 30
1-1 Individual prescription order system
------------------------------ 32
1-2 Complete floor stock system
--------------------------------------- 33
1-3 Charge floor stock drugs and non-charge floor stock
drugs --- 34
1-4 Combination of Individual prescription order system
and
Complete floor stock system ---------------------------------------35
1-5 Unit dose system
----------------------------------------------------- 35
1-6 Unit dose dispensing procedure
------------------------------------ 37
2.Drug Distribution and Control (unit dose section)
--------------------- 40
7. Unit
review----------------------------------------------------------------------------- 80
References
------------------------------------------------------------------ 81
Hospital Pharmacy
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UNIT -1
INTRODUCTION
TO HOSPITAL PHARMACY
Hospital Pharmacy
5
DEFINITION OF HOSPITAL AND HOSPITAL PHARMACY
Hospital
The hospital is a complex organization utilizing
combination of intricate,
specialized scientific equipment, and functioning
through a corps of
trained people educated to the problem of modern
medical science. These
are all welded together in the common purpose of
restoration and
maintenance of good health
Hospital Pharmacy
The department or service in a hospital which is under
the direction of a
professionally competent, legally qualified pharmacist,
and from which
all medications are supplied to the nursing units and
other services, where
special prescriptions are filled for patients in the
hospital, where
prescriptions are filled for ambulatory patients and
out-patients, where
pharmaceuticals are manufactured in bulk, where
narcotic and other
prescribed drugs are dispensed, where injectable
preparations should be
prepared and sterilized, and where professional supplies
are often stocked
and dispensed.
The computerization of the pharmacy department
makes it possible for
the staff to participate in patient education
programs, poison control
center activities, preparation of patient drug use
profiles, parenteral
profession of pharmacy.
2. To assist in providing an adequate supply of such
qualified hospital
pharmacists.
3. To assure a high quality of professional practice
through the
establishment and maintenance of standards of
professional ethics,
education, and attainments and through the
promotion of economic
welfare.
4. To promote research in hospital pharmacy practices
and in the
pharmaceutical sciences in general.
5. To disseminate pharmaceutical knowledge by providing
for
interchange of information among hospital pharmacists
and with
members of allied specialties and professions.
More broadly, the Society's primary purpose is the
advancement of
rational, patient-oriented drug therapy in hospitals
and other organized
RESIDENTS
PHARMACIST IN-CHIEF
ASSOCIATE DIRECTOR
Fig (1-1). Departmental organization
Hospital Pharmacy
15
ADMINISTRATIVE SERVICES
DIVISION
UNIT DOSE DISPENSING
AND
ADMINSTRATION
EDUCATION & TRANING
DIVISION
ASSOCIATE
DIRECTOR OF PHARMACY
DIRECTOR OF PHARMACY
PHARMMCEUTICAL
RESEARCH DIVISIONS
RESEARCH
PHARMACIST
RADIOPHARMACEUTICAL
DIVISIONS
PHARMACIST
SPECIALIST
RADIOPHARMACEUTICAL
DIVISIONS
DRUG INFORMATION
SERVICES
ASSISTANT
DIRECTOR OF PHARMACY
ASSAY & QUALITY
CONTROL DIVISION
DRUG INFORMATION
SERVICES
CENTRAL SUPPLY
DIVISION
ASSISTANT
DIRECTOR OF PHARMACY
IN-PATIENT SERVICES
DIVISION
OUT-PATIENT SERVICES
DIVISION
INTRAVENOUS
ADMIXTURE DIVISION
ASSISTANT
DIRECTOR OF PHARMACY
DEPARTMENTAL
SERVICES
PURCHASE AND
INVENTORY CONTROL
MANUFACTURING AND
PACKAGING
Fig (1-2). Departmental organization in a large university
hospital pharmacy operation
Hospital Pharmacy
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Administrative Services Division
1. Plan and coordinate departmental activities.
2. Develop policies.
3. Schedule personnel and provide supervision.
4. Coordinate administrative needs of the Pharmacy and
Therapeutics
Committee.
Hospital Pharmacy
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PHARMACY AND THERAPEUTICS COMMITTEE
The multiplicity of drugs available and the
complexities surrounding
their safe and effective use make it necessary for
hospitals to have an
organized, sound program for maximizing rational
drug use. The
pharmacy and therapeutics committee, or its
equivalent, is the
organizational keystone of the program.
The pharmacy and therapeutics committee is an advisory
group of the
medical staff and serves as the organizational line of
communication
between the medical staff and pharmacy department.
This committee is
composed of physicians, pharmacists, and other
health professionals
selected with the guidance of the medical staff. It is
a policyrecommending body to the medical staff and the
administration of the
administered to them.
(2) All doses of medication required at the nursing
station are
prepared by the pharmacy thus allowing the nurse
more time
for direct patient care.
(3) Allow the pharmacists to interpret or check a
copy of the
physicians original order thus reducing medication
errors.
(4) Elimination excessive duplication of orders and paper
work at
the nursing station and pharmacy.
(5) Eliminates credits.
(6) Transfers intravenous preparation and drug
reconstitution
procedures to the pharmacy.
Hospital Pharmacy
36
(7) Promotes more efficient utilization of professional
and nonprofessional personnel.
(8) Reduces revenue losses.
40
DRUG DISTRIBUTION AND CONTROL
(UNIT DOSE SECTION)
Medication distribution is the responsibility of the
pharmacy. The
pharmacist, with the assistance of the pharmacy and
therapeutics
committee and the department of nursing, must
develop comprehensive
policies and procedures that provider for the safe
distribution of all
medications and related supplies to inpatients and
outpatients.
For reasons of safety and economy, the preferred
method to distribute
drugs in institutions is the unit dose system. Though the
unit dose system
may differ in form depending on the specific needs,
resources, and
characteristics of each institution, for elements are
common to all.
Elements of unit dose distribution:
(1) Medications are contained in, and administered
from, single unit or
unit-dose packages
(2) Medications are dispensed in ready-to-administer
form, to the extent
possible
(3) For most medications, not more than a 24-hour
supply of doses is
provided to or available at the patient care area at any
time
(4) A patient medication profile is concurrently
maintained in the
pharmacy for each patient. Floor stocks of drugs are
minimized and
limited to drugs for emergency use and routinely used
safe items such
mouthwash and antiseptic solutions.
Hospital Pharmacy
41
Fig (2-4). Daily controlled drugs administration form
Hospital Pharmacy
42
Writing the Order:
Medications should be given (with certain specified
exceptions) only on
practitioner.
Controlled Substances: A drug or other substance, or
immediate
precursor, included in schedule I, II, III, IV or V of Part B of
this title.
The term dose not includes distilled spirits, wine,
malt beverages or
tobacco.
Depressant Or Stimulant Substance:
[A] a drug which contain any quantity of (1) barbituric
acid or any of the
salts of barbituric acid; or (2) any derivative of barbituric
acid ;or
[B] a drug which contains any quantity of (1)
amphetamine or any of its
optical isomers; (2) any salt of amphetamine or any
salt of an optical
isomer of amphetamine; or (3) any substance which
the Attorney
General, after investigation, has found to be, and by
regulation designated
as habit-forming because of its stimulant effect on
the central nervous
system; or
0
The preparation of parenteral hyperalimentation
solutions must be
considered as an integral part of the pharmacy
department's manufacturing program irrespective of
its size. The procedures employed are
not unduly complicated and do not require extensive
capital outlay for
equipment.
Most hospital pharmacists prepare these solutions by
using a technique
described as the "wet method" through the
extemporaneous compounding techniques of an
intravenous admixture program.
10
This consists of mixing the dextrose solution from
one flask with the fibrin
hydrolysate solution in anotherflask utilizing a solution
transfer set. In
the "dry method" the pharmacist adds the
appropriate amount of
anhydrous glucose to the fibrin hydrolysate solution.
Both
methods must be carried out under a laminar flow hood.
times.
Once the content of the box has been established and the
responsibility
for its stocking assigned, the units should be prepared
and placed on each
pavilion, in the clinic, in the emergency ward and in
the special
procedures room of the department of radiology.
After the emergency boxes have been placed on the
ward, it is mandatory
that a program be developed whereby they are checked
daily either by the
hospital pharmacist or by the nursing supervisor
responsible for the ward.
The following list of contents is provided to serve as a
guide.
Hospital Pharmacy
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Hospital Pharmacy
65
Unit Review
1- What are the four classes of drug distribution systems?
DEFINITIONS:
Ambulatory care, primary care, tertiary care, emergency
care
"Ambulatory" refers to patients not occupying beds in
hospitals
or other in patient settings, and to care given in
physicians' offices,
clinics, health centers, and other places where
ambulatory patients
usually go for health care. Today hospitals break
down their
ambulatory patient load into three categories
emergency, referral or
tertiary care and primary care. The term emergency
care is self
explanatory and tertiary caremeans care beyond that of
primary care.
Stated simply, primary health care is what most people
use most of the
time for most of their health problems. Primary care is
majority care.
It describes a range of services adequate for meeting the
great majority
PHARMACEUTICAL SERVICES
Services to ambulatory patients are an important
part of many
institutional pharmacy programs. The need for such
services probably
will increase substantially in the 1980s.
The Society has identified 12 activities in which
institutional
pharmacists will be involved in the ambulatory-care
setting. However,
providing all these services in all institutions at all times
is not feasible.
At a minimum, ambulatory patients require certain
critical
pharmaceutical services. The essential elements of any
ambulatory-care
pharmaceutical service program are as follows:
1. The ambulatory-care pharmacy program must be
directed by a
qualified pharmacist.
2. The appropriateness of the choice of drug and its
dosage, route of
administration, and amount must be verified by the
pharmacist. This
721Hwntington Avenue
Boston 15, Moss.
Fig (3-1) Prescription call check used in the out patient
dispensing pharmacy as a
means of matching the correct patient and prescription
PRESCRIPTION CHECK
No. 5007
PRICE
PETER BENT BRIGHAM HOSPITAL
721Hwntington Avenue
Boston 15, Moss.
To avoid errors please present this
Check when calling for your
Prescription
--Pharmacy Portion
No. 5007
Hospital Pharmacy
75
THE CHILDREN'S HOSPITAL.
MEDICAL CENTER
300LONGWOODAVE.. BOSTON 02115
No 2720
RETAIN THIS CHECK
NOTB TO
PHYSICIAN
1. Pill in both section of
prescription, including
signature.
2. Write directions in
English in lower
section as this serves
as label.
DATE
Philadelphia General Hospital
Date Prescription No
Clinic
Patient
Address
CODE
R
M.D
AMOUNT
M.S.S.W.
Amount
No
2720
PhiladelphiaGeneralHospital
Prescription No Date
Patient
DIRECTIONS
M.D
Form 76
Fig (3-3). A prescription blank developed by the children's
hospital medical center in
Boston. Note the emphasis on the patient's age
Hospital Pharmacy
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INVENTORY CONTROL
CENTRAL STORAGEVS. PHARMACY STORAGE
The dichotomous storage arrangement of supplies is
prevalent in
many hospitals, although it is common knowledge that
central storage
is ideal.
The proponents of centralized storage facilities are
quick to demonstrate the reduction in labor and record
keeping, as well as the tight
control afforded by centralization.
In contrast, it should be pointed out that the
responsibility for the
storage of drugs should be placed with competent
individuals who have
been educated, trained and licensed to handle
pharmaceuticals. These
individuals are the pharmacists.
In order that the pharmacist may properly supervise
the storage of
drugs, they should be stored in an area directly under his
control. This
allows him the freedom of stock arrangement, instituting
of inventory
controls, the adjustment of inventory based upon his
knowledge of the
prescribing trends of the staff and the preparation of
inventory cost
reports to management.
80
Unit Review
1- Define the following:
Ambulatory care
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Primary care
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Tertiary care
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Emergency care
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------2- Mention the minimum standard for
ambulatory- care pharmaceutical
services
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------3- What are the methods of
arrangement of drugs and inventory control in