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    Pathology Assignment 3

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    mah_hero
    This document outlines 35 questions for a pathology assignment covering various topics in hematology and oncology. The questions address topics such as hematopoiesis, types of anemia including iron deficiency anemia, megaloblastic anemia, and anemia of chronic disease. Other questions cover leukemias and lymphomas including molecular pathogenesis, WHO classifications, and specific diseases like Burkitt's lymphoma. Additional hematology topics include coagulation disorders, platelet function tests, and disorders like DIC and Plummer Vinson syndrome. The objective is for students to study these topics in depth.

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    Pathology Assignment 3

    Uploaded by

    mah_hero
    90 views3 pages
    This document outlines 35 questions for a pathology assignment covering various topics in hematology and oncology. The questions address topics such as hematopoiesis, types of anemia including iron deficiency anemia, megaloblastic anemia, and anemia of chronic disease. Other questions cover leukemias and lymphomas including molecular pathogenesis, WHO classifications, and specific diseases like Burkitt's lymphoma. Additional hematology topics include coagulation disorders, platelet function tests, and disorders like DIC and Plummer Vinson syndrome. The objective is for students to study these topics in depth.

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    This document outlines 35 questions for a pathology assignment covering various topics in hematology and oncology. The questions address topics such as hematopoiesis, types of anemia including iron deficiency anemia, megaloblastic anemia, and anemia of chronic disease. Other questions cover leukemias and lymphomas including molecular pathogenesis, WHO classifications, and specific diseases like Burkitt's lymphoma. Additional hematology topics include coagulation disorders, platelet function tests, and disorders like DIC and Plummer Vinson syndrome. The objective is for students to study these topics in depth.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    90 views3 pages

    Pathology Assignment 3

    Uploaded by

    mah_hero
    This document outlines 35 questions for a pathology assignment covering various topics in hematology and oncology. The questions address topics such as hematopoiesis, types of anemia including iron deficiency anemia, megaloblastic anemia, and anemia of chronic disease. Other questions cover leukemias and lymphomas including molecular pathogenesis, WHO classifications, and specific diseases like Burkitt's lymphoma. Additional hematology topics include coagulation disorders, platelet function tests, and disorders like DIC and Plummer Vinson syndrome. The objective is for students to study these topics in depth.

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    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    of 3

    Pathology Assignment

    MD 4 Summer 2015
    1. Please draw the Hematopoiesis flow chart from Stem cell to mature
    cell (both Myeloid and lymphoid series).
    2. Explain in a flowchart - hemolytic anemia leading to gall stones
    3. What are the lab findings in intravascular hemolysis and extra
    vascular hemolysis
    4. Explain hereditary spherocytosis
    5. What are Heinz bodies, Howell Jolly bodies
    6. For each of the following give few conditions where we see those
    cells in peripheral blood and reasons that are causing appearance of
    those cells in each condition
    a. Anisocytosis
    b. Poikilocytosis
    c. Tear drop cell
    d. Bite cell
    e. Schistocyte
    7. How G6PD deficiency can lead to hemolytic anemia, please write
    flow chart of G6PD role in production of NADPH and break down of
    H2O2
    8. Please write down pathophysiology of sickle cell anemia
    9. How sickle cell anemia can lead to autosplenectomy
    10. Explain both alfa and beta thalssemias in detail ( including
    subtypes)
    Iron deficiency Anemia
    11. Explain absorption and transportation of Iron in to the body
    12. What is the normal iron content in the body
    13. What are transferrin, haptoglobin, hepcidin, total iron binding
    capacity
    14. Pathogenesis Anemia of chronic disease can lead to iron deficiency
    anemia
    15 Lab findings in Anemia of chronic disease
    Megaloblastic anemia:
    16. How B12 & folic acid deficiency can lead to megaloblastic anemia (
    flow chart)
    17. Differences between folate and megaloblastic anemias and lab
    differences

    18. How B12 is absorbed in the body


    19. Pathogenesis of Aplastic anemia
    20 What is myelophthisic anemia
    21. Explain the difference between leukemia and leucocytosis and how
    do we differentiate in lab
    22. Please write a note on diagnostic procedures discussed in this
    article http://blogs.nejm.org/now/index.php/a-girl-withseizures/2015/05/22/
    23. What is the molecular pathogenesis of leukemias and lymphomas
    24. Explain Burkitts lymphoma
    25. Explain Reed sternberg cell and its effect on immunity and
    inflammation
    26. Write down 'practical classification of NHL' .
    27. For each of the type of NHL write down
    a. Predominant cell
    b. CD marker
    c. Translocation if any
    d. Signs and symptoms
    28. Explain Mycosis Fungoides, pathology and signs and symptoms
    29. For ALL, AML, CLL, CML please write down
    a. Trans location
    b. Predominant cell
    c. Signs and synptoms
    30. Please write down WHO classification of Hodkins Lymphoma
    31. Please draw the flowcytometry of AML and ALL.
    32. Explain various types of Plasma cell dyscrasias and how do we
    differentiate each from each other
    33. Explain translocation 9/22 and how it can lead to leukemia
    34. Please draw flow chart of coagulation cascade explaining intrinsic
    and extrinsic pathways.
    35. What are Bernard soulier syndrome and glansman thromboesthenia
    36. What are normal PT and aPTT.
    37. Why there can be DIC in AML 3
    38. What is plummer winson syndrome

    PS: Some questions about leukemias are repeated from in class


    assignment. If you did submit them already, you don't have to do it
    again. Study it again though. :)
    The objective of this assignment is that you study the topic in detail.
    Good luck. Good day.

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