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Textbook of Cosmetic Dermatology

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SERIES IN COSMETIC AND LASER THERAPY

Series Editors
David J Goldberg, Nicholas J Lowe, and Gary P Lask
Published in association with the Journal of Cosmetic and Laser Therapy

David J Goldberg, Fillers in Cosmetic Dermatology, ISBN 9781841845098

Philippe Deprez, Textbook of Chemical Peels, ISBN 9781841842954
C William Hanke, Gerhard Sattler, Boris Sommer, Textbook of Liposuction, ISBN 9781841845326
Paul J Carniol, Neil S Sadick, Clinical Procedures in Laser Skin Rejuvenation, ISBN 9780415414135
David J Goldberg, Laser Hair Removal, Second Edition, ISBN 9780415414128
Benjamin Ascher, Marina Landau, Bernard Rossi, Injection Treatments in Cosmetic Surgery, ISBN 9780415386517

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Avi Shai, Robert Baran, Howard I. Maibach, Handbook of Cosmetic Skin Care, Second Edition, ISBN 9780415467186
Jenny Kim, Gary Lask, Comprehensive Aesthetic Rejuvenation: A Regional Approach, ISBN 9780415458948
Neil Sadick, Paul Carniol, Deborshi Roy, Luitgard Wiest, Illustrated Manual of Injectable Fillers, ISBN 9780415476447
Paul Carniol, Gary Monheit, Aesthetic Rejuvenation Challenges and Solutions: A Global Perspective, ISBN 9780415475600
Neil Sadick, Diane Berson, Mary P Lupo, Zoe Diana Draelos, Cosmeceutical Science in Clinical Practice, ISBN 9780415471145
Anthony Benedetto, Botulinum Toxins in Clinical Dermatology, Second Edition, ISBN 9780415476362
Robert Baran, Howard I. Maibach, Textbook of Cosmetic Dermatology, Fourth Edition, ISBN 9781841847009
David J Goldberg, Alexander L Berlin, Disorders of Fat and Cellulite, ISBN 9780415477000
Kenneth Beer, Mary P Lupo, Vic Narurkar, Cosmetic Bootcamp Primer, ISBN 9781841846989

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Textbook of Cosmetic Dermatology

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Fourth Edition

Edited by

Robert Baran, MD
Nail Disease Center
Cannes, France

Howard I. Maibach, MD
Department of Dermatology
University of California San Francisco, School of Medicine
San Francisco, California, U.S.A.

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CRC Press
Taylor & Francis Group
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Boca Raton, FL 33487-2742
2011 by Taylor & Francis Group, LLC
CRC Press is an imprint of Taylor & Francis Group, an Informa business
No claim to original U.S. Government works
Version Date: 20130212
International Standard Book Number-13: 978-1-84184-764-1 (eBook - PDF)
This book contains information obtained from authentic and highly regarded sources. While all reasonable efforts have been made to publish reliable
data and information, neither the author[s] nor the publisher can accept any legal responsibility or liability for any errors or omissions that may be made.
The publishers wish to make clear that any views or opinions expressed in this book by individual editors, authors or contributors are personal to them
and do not necessarily reflect the views/opinions of the publishers. The information or guidance contained in this book is intended for use by medical,
scientific or health-care professionals and is provided strictly as a supplement to the medical or other professionals own judgement, their knowledge of
the patients medical history, relevant manufacturers instructions and the appropriate best practice guidelines. Because of the rapid advances in medical science, any information or advice on dosages, procedures or diagnoses should be independently verified. The reader is strongly urged to consult the
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Once again this book is dedicated to Nicole,

without whom it would not exist,
with appreciation, respect, admiration, and deep affection

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Preface

The fourth edition of the Textbook of Cosmetic Dermatology focuses on the evidencebased approach to cosmetic skin, hair, and nail science. Preceding editions published contrasting observations; this edition benefits from the increasing numbers of
individuals who have directed their work to controlled observations in cutaneous
biology as it relates to skin care. Although this textbook was originally intended for
the dermatologist, we are pleased that cosmetic scientists have found this view of
cutaneous biology of value and have supported us in blending the traditional
cosmetic science with skin biology.
We appreciate the hard work and suggestions of our authors and readers and
welcome suggestions for a future edition.
The editorial wisdom of our publisher, Robert Peden, is greatly appreciated.
Robert Baran
Howard I. Maibach

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Contents

Preface . . . . . . . . . . . vi
Contributors . . . . . . xi
Section I: Influences on Skin

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1. Skin physiology and gender . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1

Ethel Tur
2. A quantitative approach to anatomy and physiology of aging skin: barrier,
dermal structure, and perfusion . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14
Jeanette M. Kamell and Howard I. Maibach
3. Climatic influence on cosmetic skin parameters . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 28
Mathias Rohr and Andreas Schrader
4. Photodamage . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 41
Karen Connolly, Camile L. Hexsel, and Henry W. Lim
Section II: Cutaneous Absorption and Cosmetology
5. Skin barrier cream efficacy: evidence based. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 47
Hongbo Zhai, Heidi P. Chan, and Howard I. Maibach
6. Using the behind-the-knee (BTK) test to evaluate lotion
transfer from products to skin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 54
Miranda A. Farage
7. Nail penetration . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 63
Xiaoying Hui, Ronald C. Wester, and Howard I. Maibach
Section III: Pharmacology of Cosmetic Products and Ingredients
8. Sensitive skin: new findings yield new insights
Miranda A. Farage and Howard I. Maibach

.............................

73

9. Hyaluronan (hyaluronic acid). . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 84

Birgit A. Neudecker, Robert Stern, and Howard I. Maibach
10. Organic acids with novel functions, a-hydroxy, aldobionic,
N-acetylamino acids, and related compounds . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 91
Ruey J. Yu and Eugene J. Van Scott
11. Retinyl propionate and related retinoids . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 106
John E. Oblong
12. Idebenone (hydroxydecyl ubiquinone) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 111
Birgit A. Neudecker, Falko Diedrich, and Howard I. Maibach
13. Antioxidants . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 115
Frank Dreher and Jens Thiele
14. Topical retinol: an efficacious solution for improvement of main
photodamage signs . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 123
Christiane Bertin and Thierry Oddos

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CONTENTS

15. Applications of total soy in skin care . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 127

Jue-Chen Liu, Jeff Wu, and Miri Seiberg
16. Kinetin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 141
Stanley B. Levy
17. Urokinase and dry skin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 144
Yuji Katsuta
18. Ceramides and the skin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 150
Clive R. Harding, David J. Moore, and Anthony V. Rawlings
19. Perfumes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 165
Jeanne Duus Johansen

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20. Do consumer relevant exposures to geraniol cause clinical allergic

contact dermatitis in man? . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 169
Jurij J. Hostynek and Howard I. Maibach
21. Survey of alternative and natural drugs in dermatology . . . . . . . . . . . . . . . . . . . . 176
Cheryl Levin and Howard I. Maibach
Section IV: Cosmetology for Non-pathological Skin
........................

180

..........................................................

188

22. Skin care products for normal, dry, and greasy skin
Celine Try, Laurence Nicod, and Philippe Humbert
23. Self-tanning products
Stanley B. Levy

24. Astringents, masks, and ancillary skin care products

Zoe Diana Draelos

.......................

192

25. Cosmeceuticals . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 196

Marianne Nelson ODonoghue
26. Photodamage: prevention . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 200
Camile L. Hexsel and Henry W. Lim
27. Photodamage: protection and reversal with topical antioxidants . . . . . . . . . . . 206
Karen E Burke
Section V: Cosmetology for Specific Locations and Conditions
28. Hair care . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 218
John Gray and Jeni Thomas
29. Dandruff and seborrheic dermatitis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 230
James R. Schwartz, Caroline W. Cardin, Yvonne M. DeAngelis,
and Thomas L. Dawson, Jr.
30. The periorbital wrinkle
Martin R. Green

........................................................

242

31. Cosmetology for normal nails . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 247

Robert Baran and Douglas Schoon
32. Cosmetics for abnormal and pathological nails . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 259
Douglas Schoon and Robert Baran
33. Hand and body lotions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 269
F. Anthony Simion and David C. Story

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CONTENTS

34. Anticellulite products and therapies . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 290

Enzo Berardesca and Manuela Carrera
35. Therapy of telangiectasia and varicose veins and their complications . . . . . 294
Robert A. Weiss and Margaret A. Weiss
36. Management of hirsutism and hypertrichosis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 302
Ralph M. Trueb
37. Pigmentation: dyschromia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 311
Thierry Passeron and Jean-Paul Ortonne
38. Introduction to practical, aesthetic, and social approaches
to appearance restoration . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 330
Victoria L. Rayner Alatorre

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39. Treatment of keloids . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 341

Joshua E. Lane, Tanda N. Lane, and John L. Ratz
40. Keratolytic treatment of acne . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 352
Ali Alikhan and Howard I. Maibach
Section VI: Skin Care for Specific Groups
41. Cosmetics for men . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 365
Robert Baran and Annick Pons-Guiraud
42. Ethnic cosmetics . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 379
Enzo Berardesca, Grazia Primavera, Manuela Carrera, and Howard I. Maibach
43. Ethnic variation in hair. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 386
Nina Otberg
44. Ethnic differences in skin properties . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 395
Naissan O. Wesley, Lily Talakoub, and Howard I. Maibach
45. The menopause, skin, and cosmetology
Michel Faure and Evelyne Drapier-Faure

......................................

405

Section VII: Cosmetological Treatments

46. Mesotherapy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 410
Evangeline B. Handog and Ma. Teresita G. Gabriel
47. Microneedles and cosmetics . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 417
Raja K. Sivamani and Howard I. Maibach
48. Photodynamic therapy in dermatology
Jacques Savary

.......................................

49. Topical 5-fluorouracil formulations in actinic keratosis treatment

Ravneet R. Kaur, Ali Alikhan, and Howard I. Maibach

.........

422
429

50. Cosmetic cryosurgery . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 434

Rodney D. Sinclair and Poorna Weerasinghe
51. Botulinum toxins . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 442
Doris Maria Hexsel and Arnold W. Klein
52. Soft tissue augmentation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 454
Emily P. Tierney and C. William Hanke
53. Bioelectricity . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 466
Ying Sun and Jue-Chen Liu

ix

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CONTENTS

54. Chemical peelings . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 482

Philippe Deprez
55. Lasers and light sources for vascular and pigmented components
of photoaging . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 494
Corinne Erickson and Robert A. Weiss
Section VIII: Noninvasive Assessment Techniques
56. An easy method to assess the antioxidative capacity
of topical formulations . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 503
Hongbo Zhai and Howard I. Maibach

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57. The antioxidative capacity of topical emulsion on ultraviolet exposure

Hongbo Zhai and Howard I. Maibach

...

505

58. Treatment and noninvasive clinical assessment of

androgenetic alopecia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 510
R. Scott Youngquist, Jeanette A. Richards, Caroline W. Cardin,
and Thomas L. Dawson, Jr.
59. Assessing the efficacy of moisturizers . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 519
Whitney Hannon
Index . . . . 543

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Contributors

University of California Davis, School of Medicine, Davis, California,

Ali Alikhan
U.S.A.

Nail Disease Centre, Cannes, France

Robert Baran

San Gallicano Dermatological Institute, Rome, Italy

Enzo Berardesca

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Christiane Bertin Skin Care Research Institute, Johnson & Johnson Group of
Companies, Issy les Moulineaux, France
Karen E. Burke Department of Dermatology, Mount Sinai Medical Center,
New York, New York, U.S.A.
P&G Beauty and Grooming, Cincinnati, Ohio,

Caroline W. Cardin
U.S.A.

San Gallicano Dermatological Institute, Rome, Italy

Manuela Carrera

Heidi P. Chan Department of Dermatology, University of California San Francisco,

School of Medicine, San Francisco, California, U.S.A.
Karen Connolly Jefferson Medical College of Thomas Jefferson University,
Philadelphia, Pennsylvania, U.S.A.
Thomas L. Dawson, Jr.

P&G Beauty and Grooming, Cincinnati, Ohio, U.S.A.

Yvonne M. DeAngelis

P&G Beauty and Grooming, Cincinnati, Ohio, U.S.A.

Clinica HERA, Empuriabrava, Spain

Philippe Deprez

Munchen, Germany

Falko Diedrich

Zoe Diana Draelos Department of Dermatology, Duke University School of

Medicine, Durham, North Carolina, U.S.A.
Evelyne Drapier-Faure
Frank Dreher

Neocutis, San Francisco, California, U.S.A.

Corinne Erickson
Maryland, U.S.A.
Miranda A. Farage
Michel Faure

Gynecology, Hopital Femmes Me`res Enfants, Lyon, France

Department of Dermatology, University of Maryland, Baltimore,

The Procter & Gamble Company, Cincinnati, Ohio, U.S.A.

Hospital Edouard-Herriot, Lyon, France

Ma. Teresita G. Gabriel Department of Dermatology, Research Institute for

Tropical Medicine, Department of Health, Muntinlupa City, Philippines
John Gray

Procter & Gamble Technical Centres Limited, Egham, U.K.

Martin R. Green

Colworth Science Park, Unilever Research, Sharnbrook, U.K.

Evangeline B. Handog Department of Dermatology, Asian Hospital and Medical

Center, Muntinlupa City, Philippines

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xii

CONTRIBUTORS

C. William Hanke Laser and Skin Surgery Center of Indiana, St. Vincents
Hospital, Carmel, Indiana, U.S.A.
Whitney Hannon

San Jose, California, U.S.A.

Clive R. Harding
Wirral, U.K.

Unilever Research and Development Port Sunlight Laboratory,

Jurij J. Hostynek Department of Dermatology, University of California San

Francisco, School of Medicine, San Francisco, California, U.S.A.
Camile L. Hexsel
Michigan, U.S.A.

Department of Dermatology, Henry Ford Hospital, Detroit,

Doris Maria Hexsel Department of Dermatology, Pontificia Universidade Catolica

do Rio Grande do Sul, and Brazilian Center for Studies in Dermatology, Porto Alegre,
Brazil

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Xiaoying Hui Department of Dermatology, University of California San Francisco,

School of Medicine, San Francisco, California, U.S.A.
Philippe Humbert
Besancon, France

Department of Dermatology, University Hospital Saint-Jacques,

Jeanne Duus Johansen National Allergy Research Centre, Department of

Dermato-Allergology, Gentofte Hospital, University of Copenhagen, Hellerup,
Denmark
Jeanette M. Kamell Department of Dermatology, University of California San
Francisco, School of Medicine, San Francisco, California, U.S.A.
Yuji Katsuta

Shiseido Research Center, Yokohama, Japan

Ravneet R. Kaur University of California Los Angeles, School of Medicine,

Los Angeles, California, U.S.A.
Arnold W. Klein Division of Dermatology, David Geffen School of Medicine,
University of California at Los Angeles and Cedars-Sinai Medical Center,
Los Angeles, California, U.S.A.
Joshua E. Lane Surgery and Internal Medicine, Mercer University School of
Medicine, Macon; Section of Dermatology, Medical College of Georgia, Augusta; and
Department of Dermatology, Emory University School of Medicine, Atlanta, Georgia,
U.S.A.
Tanda N. Lane Department of Dermatology, Emory University School of Medicine,
Atlanta, Georgia, U.S.A.
Cheryl Levin

San Diego, California, U.S.A.

Stanley B. Levy Revlon Research Center, Edison, New Jersey and Chapel Hill
Dermatology, Chapel Hill, North Carolina, U.S.A.
Henry W. Lim Department of Dermatology, Henry Ford Hospital, Detroit,
Michigan, U.S.A.
Jue-Chen Liu
U.S.A.

Johnson & Johnson Consumer Personal Group, Stillman, New Jersey,

Howard I. Maibach Department of Dermatology, University of California San

Francisco, School of Medicine, San Francisco, California, U.S.A.
David J. Moore

International Speciality Products, Wayne, New Jersey, U.S.A.

Birgit A. Neudecker Department of Dermatology, University of California San

Francisco, School of Medicine, San Francisco, California, U.S.A.

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CONTRIBUTORS

Laurence Nicod Cellular Biology and Genetic Laboratory, University Hospital

Saint-Jacques, Besancon, France
The Procter & Gamble Company, Cincinnati, Ohio, U.S.A.

John E. Oblong

Thierry Oddos Department of Pharmacology, Johnson & Johnson Group of

Companies, Val de Reuil, France
Marianne Nelson ODonoghue Department of Dermatology, Rush University
Medical Center, Chicago, Illinois, U.S.A.
Department of Dermatology, University Hospital of Nice,

Jean-Paul Ortonne
France

San Gallicano Dermatological Institute, Rome, Italy

Grazia Primavera

Nina Otberg Skin and Laser Center Potsdam, Hair Clinic, Potsdam and Hair
Transplant Center BerlinPotsdam, Berlin, Germany

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Thierry Passeron Department of Dermatology & INSERM U895 Team 1, University

Hospital of Nice, France
Annick Pons-Guiraud
John L. Ratz

Paris, France

Tifton, Georgia, U.S.A.

Anthony V. Rawlings

AVR Consulting Ltd., Cheshire, U.K.

Victoria L. Rayner Alatorre

Florida, U.S.A.
Jeanette A. Richards
Mathias Rohr

Aesthetic Advocates for America, Orlando,

P&G Beauty and Grooming, Cincinnati, Ohio, U.S.A.

Institut Dr. Schrader Hautphysiologie, Holzminden, Germany

Galderma International, La Defense, Paris, France

Jacques Savary

Science and Technology, Creative Nail Design Inc., Vista,

Douglas Schoon
California, U.S.A.

Institut Dr. Schrader, Hautphysiologie, Holzminden, Germany

Andreas Schrader
James R. Schwartz
U.S.A.

P&G Beauty and Grooming, Cincinnati, Ohio,

Miri Seiberg Johnson & Johnson Consumer Personal Group, Stillman,

New Jersey, U.S.A.
F. Anthony Simion

Kao Brands Co., Cincinnati, Ohio, U.S.A.

Rodney D. Sinclair Department of Dermatology, University of Melbourne and

St. Vincents Hospital, Melbourne, Victoria, Australia
Raja K. Sivamani Department of Dermatology, University of California Davis,
School of Medicine, Davis, California, U.S.A.
Robert Stern Pathology, Division of Basic Medical Sciences, Touro College of
Osteopathic Medicine, New York, New York, U.S.A.
David C. Story
Ying Sun
U.S.A.

Kao Brands Co., Cincinnati, Ohio, U.S.A.

Johnson & Johnson Consumer Personal Group, Skillman, New Jersey,

Lily Talakoub
U.S.A.

Center for Dermatology and Dermatologic Surgery, Washington, D.C.,

xiii

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xiv

CONTRIBUTORS

Dermatology Specialists, Inc., Oceanside, California, U.S.A.

Jen Thiele
Jeni Thomas

P&G Beauty and Grooming, Cincinnati, Ohio, U.S.A.

Emily P. Tierney Laser and Skin Surgery Center of Indiana, St. Vincents Hospital,
Carmel, Indiana, U.S.A.
Ralph M. Trueb

Center for Dermatology and Hair Diseases, Zurich, Switzerland

Celine Try Department of Dermatology, University Hospital Saint-Jacques,

Besancon, France
Ethel Tur Department of Dermatology, Tel Aviv University Sackler School of
Medicine, Tel Aviv, Israel
Eugene J. Van Scott

Abington, Pennsylvania, U.S.A.

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Poorna Weerasinghe Department of Dermatology, University of Melbourne,

Melbourne, Victoria, Australia
Margaret A. Weiss Department of Dermatology, Johns Hopkins University School
of Medicine, Baltimore, and Laser Skin and Vein Institute, Hunt Valley, Maryland,
U.S.A.
Robert A. Weiss Department of Dermatology, Johns Hopkins University School
of Medicine, Baltimore, and Laser Skin and Vein Institute, Hunt Valley, Maryland,
U.S.A.
Naissan O. Wesley
California, U.S.A.

Skin Care and Laser Physicians of Beverly Hills, Los Angeles,

Ronald C. Wester Department of Dermatology, University of California San

Francisco, School of Medicine, San Francisco, California, U.S.A.
Jeff Wu
U.S.A.

Johnson & Johnson Consumer Personal Group, Stillman, New Jersey,

R. Scott Youngquist
Ruey J. Yu

P&G Beauty and Grooming, Cincinnati, Ohio, U.S.A.

Chalfont, Pennsylvania, U.S.A.

Hongbo Zhai Department of Dermatology, University of California San Francisco,

School of Medicine, San Francisco, California, U.S.A.