The international unit (IU) is a unit of measurement used for biologically active substances like vitamins, hormones, medications, and blood products. The mass or volume that constitutes one IU varies between substances based on their biological activity or effect. For each substance, an international expert committee sets a reference preparation and arbitrarily assigns it a number of IUs. They also specify a biological assay to compare other preparations of that substance to the reference. Since IU assignments are arbitrary, there is no equivalence between IU measurements of different biological agents. IU values are provided for several vitamins to illustrate their definitions relative to common forms of those vitamins.
The international unit (IU) is a unit of measurement used for biologically active substances like vitamins, hormones, medications, and blood products. The mass or volume that constitutes one IU varies between substances based on their biological activity or effect. For each substance, an international expert committee sets a reference preparation and arbitrarily assigns it a number of IUs. They also specify a biological assay to compare other preparations of that substance to the reference. Since IU assignments are arbitrary, there is no equivalence between IU measurements of different biological agents. IU values are provided for several vitamins to illustrate their definitions relative to common forms of those vitamins.
The international unit (IU) is a unit of measurement used for biologically active substances like vitamins, hormones, medications, and blood products. The mass or volume that constitutes one IU varies between substances based on their biological activity or effect. For each substance, an international expert committee sets a reference preparation and arbitrarily assigns it a number of IUs. They also specify a biological assay to compare other preparations of that substance to the reference. Since IU assignments are arbitrary, there is no equivalence between IU measurements of different biological agents. IU values are provided for several vitamins to illustrate their definitions relative to common forms of those vitamins.
The international unit (IU) is a unit of measurement used for biologically active substances like vitamins, hormones, medications, and blood products. The mass or volume that constitutes one IU varies between substances based on their biological activity or effect. For each substance, an international expert committee sets a reference preparation and arbitrarily assigns it a number of IUs. They also specify a biological assay to compare other preparations of that substance to the reference. Since IU assignments are arbitrary, there is no equivalence between IU measurements of different biological agents. IU values are provided for several vitamins to illustrate their definitions relative to common forms of those vitamins.
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International unit
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In pharmacology, the international unit is a unit of measurement for the amount of a substance; the mass or volume that constitutes one international unit varies based on which substance is being measured, and the variance is based on the biological activity or effect, for the purpose of easier comparison across substances. International units are used to quantify vitamins, hormones, somemedications, vaccines, blood products, and similar biologically active substances. Many biological agents eist in different forms or preparations !e.g. vitamin " in the form of retinol or beta #carotene $. %he goal of the I& is to be able to compare these, so that different forms or preparations with the same biological effect will contain the same number of I&s. %o do so, the W'( )pert *ommittee on +iological ,tandardi-ation provides a reference preparation of the agent, arbitrarily sets the number of I&s contained in that preparation, and specifies a biological procedure to compare other preparations of the same agent to the reference preparation. ,ince the number of I&s contained in a new substance is arbitrarily set, there is no equivalence between I& measurements of different biological agents. For instance, one I& of vitamin ) cannot be equated with one I& of vitamin " in any way, including mass or efficacy. Vitamin A: 1 IU is the biological equivalent of 0.3 g retinol, or of 0.6 g beta- carotene [6[! Vitamin C: 1 IU is "0 g #-ascorbic aci$ Vitamin D: 1 IU is the biological equivalent of 0.0%" g cholecalciferol&ergocalciferol Vitamin E: 1 IU is the biological equivalent of about 0.66! 'g $-al(ha- toco(herol )%&3 'g e*actl+,, or of 0.-" 'g of $l-al(ha-toco(herol acetate. [.[/ Insulin: 1 IU is equivalent to 0.03-! 'g of hu'an insulin )%... IU&'g,. .itamin " / I& 0 1.2 mcg all#trans retinal 0 1.2 mcg retinol 0 1.233 mcg retinyl acetate 0 1.44 mcg retinyl palmitate 0 2.5 mcg +eta# *arotene / mcg 6etinol 0 2.23 I& of vitamin " activity / mg of all#trans +eta#*arotene 0 /557 I& of .itamin " activity / mcg +eta#*arotene 0 /.57 I& of .itamin " activity / mcg dietary +eta#*arotene 0 1./57 mcg retinal 6etinol )quivalents !6)$ 0 the .itamin " activity in foods / 6) 0 / mcg all#trans retinal 0 / mcg retinal 0 2.22 I& 6etinol / 6) 0 5 mcg all#trans +eta#*arotene 0 5 mcg +eta#*arotene / 6) 0 /8 mcg other provitamin " carotenoids .itamin ) / I& 0 1.57 mg of d#alpha#tocopherol or 1.34 dl#alpha#tocopherol / mg 0 /.39 I& d#alpha#tocopherol !natural vitamin ); 666#alpha#tocopherol$ / mg 0 /./1 dl#alpha#tocopherol !synthetic vitamin ); all#rac#alpha#tocopherol$ .itamin : / I& 0 1.184 mcg of cholecalciferol !.itamin :2$ / mcg .itamin : !cholecalciferol$ 0 31 I&
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