Tissues Lect Apd
Tissues Lect Apd
Tissues Lect Apd
Dr. S. Meyer
TISSUES
Tissues = layers/ groups of similar cells with a common function Study of tissues = histology
Muscle Tissue
Nervous Tissue
Type
Function
Protection Secretion Absorption Excretion
Location
Cover body surface Cover & line internal organs Compose glands
Distinguishing Characteristics
Lack blood vessels Cells readily divide Cells are tightly packed
Epithelial
Connective
Bind, support Protect Fill spaces, Store fat Produce blood cells
Mostly have good blood supply Cells further apart with extracellular matrix in between
Muscle
Movement
Attached to bones In walls of hollow internal organs Heart Brain Spinal cord Nerves
Nervous
TISSUES
Many cell types are tightly packed with structures called intercellular junctions that connect their cell membranes Tight junctions: fuse neighboring cell membranes
Tight junction Cell membrane Cell membrane
Gap junctions: tubular channels that allow small molecules to move between the cytoplasm of adjacent cells
Cell membrane
Gap junction
EPITHELIAL TISSUES
General Characteristics:
Cover organs and the body Line body cavities Line hollow organs Have a free/apical surface: exposed to outside or internally to an open space Have a basement membrane: anchors epithelium to underlying connective tissue Are avascular: lack blood vessels Cells readily divide
EPITHELIAL TISSUES
CLASSIFICATION
Number of layers of cells:
Simple: single layer of cells Stratified: two or more layers of cells
EPITHELIAL TISSUES
Simple Squamous Epithelium:
Single layer of flattened cells
EPITHELIAL TISSUES
Simple Cuboidal Epithelium:
Single layer of cube-shaped cells Cells have centrally located sperical nuclei
EPITHELIAL TISSUES
Simple Columnar Epithelium:
Single layer of elongated cells Nuclei usually near the basement Membrane at same level Sometimes possess cilia or microvilli Often have goblet cells (secrete mucus) Functions: secretion & absorption Line uterus, stomach, intestines
Mucus Nucleus Cytoplasm Microvilli (free surface of tissue) Goblet cell Basement membrane Connective tissue
EPITHELIAL TISSUES
Pseudostratified Columnar Epithelium:
Single layer of elongated cells
Appears stratified/layered, but is not Nuclei at two or more levels Often have goblet cells (secrete mucus) Often have cilia (sweep away mucus) Line respiratory passageways
EPITHELIAL TISSUES
Stratified Squamous Epithelium:
Many cell layers Top cells are flat Outer layer of skin = epidermis Can accumulate keratin (protein) in skin Line oral cavity, vagina, and anal canal (not
EPITHELIAL TISSUES
Stratified Cuboidal Epithelium:
2-3 layers Cube-shaped cells Form the lining of a lumen (space in tubular structure) Line ducts of mammary glands, sweat glands, salivary glands, and the pancreas
Stratified cuboidal epithelium Nucleus Lumen Free surface of tissue Basement membrane Connective tissue
EPITHELIAL TISSUES
Stratified Columnar Epithelium:
Several layers of cells
Top layer of elongated cells Cube-shaped cells in deeper layers Line part of male urethra and part of pharynx
Lumen Free surface of tissue Stratified columnar epithelium Basement membrane Connective tissue
EPITHELIAL TISSUES
Transitional Epithelium:
Many cell layers Cube-shaped and elongated cells Specialized to change in response to increased tension Forms inner lining of urinary bladder, ureters, and part of urethra
EPITHELIAL TISSUES
Glandular Epithelium:
Composed of cells that are specialized to produce and secrete substances There are two (2) types: Endocrine glands: ductless; secrete their products (hormones) into tissue fluid or blood Exocrine glands: secrete their products into ducts that open onto surfaces e.g. skin or lining of digestive tract
EXOCRINE GLANDS
Unicellular exocrine gland:
Merocrine Glands A fluid product released through the cell membrane by exocytosis
Salivary glands Sweat glands of skin
Apocrine Glands Cellular product & portions of the free ends of glandular cells pinch off during secretion
Mammary glands
Pinched off portion of cell (secretion)
Intact cell
Secretion
CONNECTIVE TISSUES
General Characteristics:
Most abundant (by weight) tissue type in body
FUNCTIONS:
Bind structures Provide support and protection
Serve as frameworks
Fill spaces Stores fat Produce blood cells Protect against infections Help repair tissue damage
CONNECTIVE TISSUES
STRUCTURE:
cells further apart
extracellular matrix between the cells extracellular matrix composed of: protein fibres ground substance (non-fibrous protein, other molecules + fluid)
consistency of ECM varies from fluid semi-solid solid Function of ECM: binds, supports & provides a medium thru which substances may be transferred between the blood & cells of the tissue CT cells can usually divide Varying degrees of vascularity Rigid CT = bone and cartilage Loose CT & dense CT = more flexible
tissues by phagocytosis
Release substances that may help prevent blood clotting & promote inflammation
Mast cells
Function
white fibers
Provide elastic quality to parts that stretch Form supportive networks within
tissues
Loose
connective
tissue
Adipose tissue
matrix
behind eyeballs
Reticular
connective
tissue
matrix
Airways
Hyaline cartilage
matrix
framework
respiratory passages
Elastic cartilage
matrix
framework
Fibrocartilage matrix
Blood
in fluid matrix
Clotting
MUSCLE TISSUES
General Characteristics:
Muscle cells also called muscle fibers (elongated)
Smooth muscle
Cardiac muscle
bones
Controlled by conscious effort = voluntary muscle tissue Long cells with striations (alternating
Move the head, trunk & limbs Enable us to make facial expressions Write, talk, sing, chew, swallow, breathe
Cytoplasm
Nucleus
NERVOUS TISSUE
Found in brain, spinal cord, and peripheral nerves Basic cells = neurons (specialized)
neuroglial cells : support and bind nervous tissue components carry on phagocytosis help supply growth factors & nutrients to neurons by connecting them to blood vessels play a role in cell-to-cell communication