5.SH-Vortrag 28-11-02-1

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Christ Water Technology Group

1 / 10.10.2002 / Schmitt G.

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THREE DIVISIONS OF BWT GROUP

BWT AG

Christ Water Technology Group (Industrial & Municipal Division)

Aqua Ecolife Technologies (Household & Homes Division)

FuMA-Tech

(Fuel Cell Division)

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KEY FIGURES OF BWT GROUP

1999 Turnover Net Profit Issued Shares Employees


Mio Mio 1,000s 245.3 9.3 16,500 1,839

2000
399.0 15.4 16,500 2,510

2001
419.5 15.2 17,833.5 2,511

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CWT GROUP

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SALES PER BUSINESS UNIT


2000
10% 49%

2002e
8% 5%

12%

22%

8%

17% 11%

20%

18%

6%

20%
35%

Semiconductor Power Generation Pharma & Life Sciences Food & Beverage Industrial Process & Waste Municipal Drinking & Sewage

11%

13%

2001
20% 16%

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COMPETENCE CENTERS
Pharma & Life Sciences Power Generation Christ GmbH, Stuttgart Germany Christ-Kennicott Water Technology Ltd, Wolverhampton UK Christ AG, Aesch Switzerland Goema GmbH, Vaihingen Germany Van der Molen GmbH, Kissing Germany Aqua Engineering GmbH, Mondsee Austria

Semiconductor Industrial Process & Waste Water Food & Beverage Municipal Drinking & Sewage Water
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Pharmaceutical industry Life-science

Due Due to to their their many many years years of of experience experience and and the the know-how know-how of of their their engineers, engineers, CHRIST CHRIST GmbH GmbH has has become become a a world-wide world-wide specialist specialist for for specific, specific, technically technically demanding demanding solutions solutions in in the the following following lines: lines:

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Water for the pharmaceutical industry

Water for the pharmaceutical industry

CHRIST CHRIST GmbH GmbH plans, plans, manufactures manufactures and and installs installs customized customized system system solutions solutions from from a a single single source. source. Made Made in in Germany Germany
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Europe

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Water: most important raw material in the pharmaceutical industry

Drinking Drinking Water Water

Purified Purified Water Water

WFI WFI (Water (Water for for Injection) Injection)


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Purified Water, limits values

Parameter Parameter

Ph. Ph. Eur. Eur.

USP USP

TOC TOC Conductivity Conductivity Conductivity Conductivity Nitrate ) Nitrate (NO (NO3 3) Heavy Heavy metals metals

[ppb [ppb C] C] [ [ 20C 20C S/cm S/cm ] ] [ [ 25C 25C S/cm S/cm ] ] [ [ ppm ppm ] ] [ [ ppm ppm as as Pb Pb ] ]

500 500 4.3 4.3 0.2 0.2 0.1 0.1 100 100

500 500 1.3 1.3 100 100

Microbial Microbial contamination contamination [ [ CFU/ml CFU/ml ] ]

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WFI / HPW, limits values

Parameter Parameter TOC TOC Conductivity Conductivity Conductivity Conductivity Nitrate ) Nitrate (NO (NO3 3) Heavy Heavy metals metals [ppb [ppb C] C] [ [ 20C 20C S/cm S/cm ] ] [ [ 25C 25C S/cm S/cm ] ] [ [ ppm ppm ] ] [ [ ppm ppm as as Pb Pb ] ]

Ph. Ph. Eur. Eur. 500 500 1.1 1.1 0.2 0.2 0.1 0.1 10 10 0.25 0.25

USP USP 500 500 1.3 1.3 10 10 0.25 0.25

Microbial Microbial contamination contamination [ [ CFU/ml CFU/ml ] ] Endotoxine Endotoxine units units
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[ [ EU/ml] EU/ml]

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FDA required trending system

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Processes

Purified water

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Ionexchanger system

AUTOSTIL conventional cation- / anion ionexchanger

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Ionexchanger system

e.g. Conductivity < 1 S/cm TOC > 500 ppb Germ count > 100 cfu / ml

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Ionexchanger system

e.g. Conductivity < 1 S/cm TOC > 500 ppb Germ count > 100 cfu / ml

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Reverse osmosis

OSMOSTIL double pass reverse osmosis

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Reverse osmosis

e.g. Conductivity ~ 1 S/cm TOC < 50 ppb Germ count < 10 cfu / 100 ml

Caustic soda addition

RO pass 1

RO pass 2

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Reverse osmosis

e.g. Conductivity ~ 1 S/cm TOC < 50 ppb Germ count < 10 cfu / 100 ml

Caustic soda addition

RO pass 1

RO pass 2

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Reverse osmosis / Electrodeionisation

OSMOTRON
latest technique to produce purified water acc. to USP and Europ. Pharmacop.

21 / 10.10.2002 / Schmitt G.

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Reverse osmosis / Electrodeionisation

e.g. Conductivity < 0.1 S/cm TOC < 50 ppb Germ count < 10 cfu / 100 ml

Reverse osmosis

Electrodeionisation

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Reverse osmosis / Electrodeionisation

e.g. Conductivity < 0.1 S/cm TOC < 50 ppb Germ count < 10 cfu / 100 ml

Reverse osmosis

Electrodeionisation

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Electrodeionisation

What is Electrodeionisation?

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CHRIST SEPTRON

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Modular Designed Systems

Capacity Brand:
X X X X X

140 l/hr - 5.000 l/hr


d e t d s e e i T li f a y u a e l t q i P s e n nd Pr o a g ng i u l l b P m se s a o N

Septron Line Osmotron - PH Osmotron - Inject Select technique Loopo

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Septron Line

The best in class

SEPTRON Line purest water


The The small small alternative alternative to to Osmotron Osmotron CHRIST CHRIST solution solution for for smaller smaller applications applications (140/400 (140/400 l/h) l/h) Purified Purified Water Water

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OSMOTRON - PH

Capacity 500 l/hr - 5000 l/hr


Water Water treatment treatment system system for for the the production production of of Pruified Pruified Water Water in accordance with in accordance with USP USP GAMP GAMP and and cGMP cGMP conditions conditions Osmotron Osmotron -- a a compact compact and and extremely extremely safe safe alternative alternative to to conventional conventional single single units units

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OSMOTRON - PH

Plu un g an dP its lay

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OSMOTRON - Inject / Select

Capacity 500 l/hr - 5000 l/hr


Water Water treatment treatment system system for for the the production production of of HPW HPW // WFI WFI in accordance with in accordance with USP USP // EP EP GAMP GAMP and and cGMP cGMP conditions conditions

30 / 10.10.2002 / Schmitt G.

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31 / 10.10.2002 / Schmitt G.

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LOOPO

Plug and play system for disinfection / distribution / monitoring


X X X X

Skid mounted and compact Pre- assembled Pre-wired Ready for connection

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LOOPO

Plu un g an dP its lay

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CHRIST solutions to meet your requirements

Preparation Water treatment systems Installation Qualification Validation Service Represented by partner companies throughout the world

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www.christ-wasser.de

www.christ-wasser.de

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