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    Allopurinol (Drug Study)

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    Daisy Palisoc
    Allopurinol is used to treat gout and hyperuricemia. It works by inhibiting xanthine oxidase to decrease uric acid levels. Common side effects include fever, drowsiness, headache, and rash. Nursing responsibilities include monitoring uric acid levels, kidney function, and side effects. The nurse educates the patient on avoiding risk factors for side effects and signs of adverse reactions.

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    Allopurinol (Drug Study)

    Uploaded by

    Daisy Palisoc
    3K views2 pages
    Allopurinol is used to treat gout and hyperuricemia. It works by inhibiting xanthine oxidase to decrease uric acid levels. Common side effects include fever, drowsiness, headache, and rash. Nursing responsibilities include monitoring uric acid levels, kidney function, and side effects. The nurse educates the patient on avoiding risk factors for side effects and signs of adverse reactions.

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    Allopurinol is used to treat gout and hyperuricemia. It works by inhibiting xanthine oxidase to decrease uric acid levels. Common side effects include fever, drowsiness, headache, and rash. Nursing responsibilities include monitoring uric acid levels, kidney function, and side effects. The nurse educates the patient on avoiding risk factors for side effects and signs of adverse reactions.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    3K views2 pages

    Allopurinol (Drug Study)

    Uploaded by

    Daisy Palisoc
    Allopurinol is used to treat gout and hyperuricemia. It works by inhibiting xanthine oxidase to decrease uric acid levels. Common side effects include fever, drowsiness, headache, and rash. Nursing responsibilities include monitoring uric acid levels, kidney function, and side effects. The nurse educates the patient on avoiding risk factors for side effects and signs of adverse reactions.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    of 2

    DRUG STUDY

    DRUG MECANISM OF INDICATION CONTRAINDICATION SIDE EFFECTS NURSING RESPONSIBILITY


    ACTION

    ALLOPURINOL Inhibits xanthine  Treatment of Severe renal impairment and CNS: Fever, drowsiness,  Assess patient’s history, gout may
    oxidase, an enzyme primary or children except those with headache, be secondary to disease such as
    involved in the secondary gout hyperuricemia secondary to paresthesia, acute or chronic leukemia,
    (Allomaron, Allurase,
    synthesis of uric acid  hyperuricemia malignancy, idiopathic peripheral polycythemia vera, multiple
    Drugmaker’s Biotech
    without disrupting the resulting from hemochromatosis, acute gouty neuropathy, neuritis. myeloma or psoriasis.
    Allopurinol, Elavil,
    biosynthesis of chemotherapy attack, hypersensitivity. CV: Hypersensitivity  Assess for pain including location,
    Llanol, Lopric,
    essential purine. for Lactation. vasculitis, necrotizing characteristics, onset/duration,
    Loricid, Purinase,
    Results in decreased malignancies angiitis. frequency, quality, intensity or
    Puristen, SYnol,
    acid level.  recurrent EENT: Epistaxis. severity of pain, precipitating
    Zelcron, Zyloprim)
    calcium oxalate GI: Diarrhea, nausea, factors.
     renal calculi vomiting, abdominal  Monitor uric acid levels every 2
    CLASSIFICATION: pain, gastritis, taste
     Recurrent weeks. Monitor renal function;
    Xanthine oxidase trophaceous loss, or perversion, check intake-output ratio, increase
    inhibitor; antigout deposits or uric dyspepsia. fluids to 2 L/day to prevent stone
    drug acid stones. GU: Renal failure, formation, toxicity, BUN,
    uremia. creatinine.
    Hematologic:  Monitor CBC and hepatic function
    Agranulocytosis, at the start of therapy and
    anemia, aplastic periodically thereafter.
    anemia,  Be alert for adverse reaction and
    thrombocytpenis, drug interaction, anemia, hepatitis.
    leucopenia,  Advaic patient to avoid hazardous
    leukocytosis, activities requiring mental
    eosinophilia. alertness until CNS effect are
    Hepatic: Hepatitis, known.
    hepatic necrosis,
     Advice patient to avoid taking
    hepatomegaly,
    large dose of vitamin C, it may
    cholestatic jaundice.
    cause kidney stone formation.
    Musculoskeletal:
    Maintain a diet enhancing urine
    Arthralgia,
    alkalinity, and if taking drug for
    myopathy.
    calcium oxalate stones, reduce
    dairy products, refined sugar,
    sodium and meat.
     Tell patient to stop drug and report
    if skin rash, stomatitis, malaise,
    and fever occur, this may precede
    hypersensitivity or adverse
    reaction.

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