Drug Study-Med Ward

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Patient Initials: Drug Name Generic Name: Tranexamic Acid Brand Name: Transamin Dosage: Route: Date ordered:

September 19 2013

J.C.R. Classification

Age: 62 years old Mechanism of Action

Admitting Diagnosis: Upper Gastrointestinal Bleeding Contraindication Side Effects Nursing Responsibilities Unusual change in bleeding pattern should be immediately reported to the physician. For women who are taking Tranexamic acid to control heavy bleeding, the medication should only be taken during the menstrual period. The medication can be taken with or without meals.

Indication Tranexamic acid is used for the prompt and effective control of hemorrhage in various surgical and clinical areas: epistaxis, hemoptysis, hematuria, peptic ulcer with hemorrhage and blood dyscrasias with hemorrhage

Anti-fibrinolytic, Tranexamic antihemorrhagic acid is a synthetic derivative of the amino acid lysine. It exerts its antifibrinolytic effect through the reversible blockade of lysine-binding sites on plasminogen molecules. Antifibrinolytic drug inhibits endometrial plasminogen activator and thus prevents fibrinolysis and

Severe Allergic reaction allergic to the drug or reactions hypersensitivity such as rash, hives, Presence of blood itching, clots (eg, in the dyspnea, leg, lung, eye, tightness in brain), have a the chest, history of blood swelling of clots, or are at the mouth, risk for blood face, lips or clots tongue Calf pain, Current swelling or administration of tenderness factor IX complex Chest pain concentrates or Confusion anti-inhibitor Coughing coagulant up blood concentrates # Decreased urination Severe or

the breakdown of blood clots. The plasminogenplasmin enzyme system is known to cause coagulation defects through lytic activity on fibrinogen, fibrin and other clotting factors. By inhibiting the action of plasmin (finronolysin) the antifibrinolytic agents reduce excessive breakdown of fibrin and effect physiological hemostasis.

persistent headache Severe or persistent body malaise Shortness of breath Slurred speech Slurred speech Vision changes

Swallow Tranexamic Acid whole with plenty of liquids. Do not break, crush, or chew before swallowing. If you miss a dose of Tranexamic Acid, take it when you remember, then take your next dose at least 6 hours later. Do not take 2 doses at once

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