PATHO

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Modifiable Factors Substance abuse Sleep deprivation Stress

Non-Modifiable Factors Genetic factors

Imbalance Serotonin And Norephinephrine level

Increase in Serotonin and Norephinephrine

Chemical changes in the brain

Kindling (a process by which seizure is initiated

Spontaneous seizure activity in the brain

%yperactivity

Signs and Symptoms (Patient based) !al"ing aimlessly #ecreased sleep Agitation An$iety %allucinations #elusions &al"ing and laughing alone

Signs and Symptoms (Book based) Abnormal and persistent elevation of mood Agitative Grandiosity #ecreased need for sleep Increase involvement in goal directed activity %allucinations

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