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    Sun Damage and Skin Cancer

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    Gede Juanamasta
    The document discusses several types of skin cancer and their risk factors, symptoms, and treatment options. It covers actinic keratosis, squamous cell carcinoma (SCC), basal cell carcinoma (BCC), and malignant melanoma. SCC risk factors include fair skin, pipe smoking, chronic UV exposure, tar/arsenic exposure, and immunosuppression. BCC risk factors include fair skin, chronic sun exposure, and genetic predisposition. Malignant melanoma risk factors include family history, number of moles, and intermittent childhood sun exposure. Treatment options mentioned include various forms of surgery, cryosurgery, radiotherapy, and topical medications depending on the type and severity of the cancer.

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    Sun Damage and Skin Cancer

    Uploaded by

    Gede Juanamasta
    15 views6 pages
    The document discusses several types of skin cancer and their risk factors, symptoms, and treatment options. It covers actinic keratosis, squamous cell carcinoma (SCC), basal cell carcinoma (BCC), and malignant melanoma. SCC risk factors include fair skin, pipe smoking, chronic UV exposure, tar/arsenic exposure, and immunosuppression. BCC risk factors include fair skin, chronic sun exposure, and genetic predisposition. Malignant melanoma risk factors include family history, number of moles, and intermittent childhood sun exposure. Treatment options mentioned include various forms of surgery, cryosurgery, radiotherapy, and topical medications depending on the type and severity of the cancer.

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    kerusakan kulit dan kanker kulit

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    The document discusses several types of skin cancer and their risk factors, symptoms, and treatment options. It covers actinic keratosis, squamous cell carcinoma (SCC), basal cell carcinoma (BCC), and malignant melanoma. SCC risk factors include fair skin, pipe smoking, chronic UV exposure, tar/arsenic exposure, and immunosuppression. BCC risk factors include fair skin, chronic sun exposure, and genetic predisposition. Malignant melanoma risk factors include family history, number of moles, and intermittent childhood sun exposure. Treatment options mentioned include various forms of surgery, cryosurgery, radiotherapy, and topical medications depending on the type and severity of the cancer.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as DOC, PDF, TXT or read online from Scribd
    Download as doc, pdf, or txt
    15 views6 pages

    Sun Damage and Skin Cancer

    Uploaded by

    Gede Juanamasta
    The document discusses several types of skin cancer and their risk factors, symptoms, and treatment options. It covers actinic keratosis, squamous cell carcinoma (SCC), basal cell carcinoma (BCC), and malignant melanoma. SCC risk factors include fair skin, pipe smoking, chronic UV exposure, tar/arsenic exposure, and immunosuppression. BCC risk factors include fair skin, chronic sun exposure, and genetic predisposition. Malignant melanoma risk factors include family history, number of moles, and intermittent childhood sun exposure. Treatment options mentioned include various forms of surgery, cryosurgery, radiotherapy, and topical medications depending on the type and severity of the cancer.

    Copyright:

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    Download as DOC, PDF, TXT or read online from Scribd
    Download as doc, pdf, or txt
    of 6

    SUN DAMAGE and SKIN CANCER

    ACTINIC KERATOSIS

    ACTINIC or SOLAR KERATOSES


    Treatment o Surgery Cryosurgery Curettage o Topical 5-fluorouracil Diclofenac sodium Tretinoin o Nothing and Observe

    SCC-Risk Factors
    Fair Skin Pipe Smoker (lip) Chronic UV exposure - PUVA Tar, arsenic Immunosuppression (renal transpalant) - HPV infection X irradiation Longstanding scars/ulcers Genetic - defective DNA repair - albino

    SCC PADA KULIT

    SCC PADA BIBIR PEROKOK

    BCC
    Clinical types Nodulo-cystic

    Superficial Pigmented Morphoeic

    BCC
    Risk Factors fair skinned patients chronic sun exposure X-irradiation chronic arsenic genetic predisposition

    BCC
    Treatment Options - excision MOHS surgery - curettage and cautery - radiotherapy

    - Cryosurgery - Topical 5 fluorouracil Imiquimod

    MALIGNANT MELANOMA
    1985 ABCD rule Asymmetry Border irregularity Color variegation Diameter of > 6 mm

    RISK FACTORS FOR MELANOMA


    >50 melanocytic naevi Atypical melanocytic naevi Family history of melanoma Mutations in CDKN2A and CDK4 genes Personal history of melanoma Risk greatest in first 2 years Fair skin Blond / red hair, blue eyes, freckles Intermittent sun exposure and sunburn in childhood Tanning beds

    TYPES OF MELANOMA
    Superfical spreading the commonest in the UK Nodular Acral Rare in UK Common in Asian and Afro-Caribbean Lentigo maligna melanoma Arises in lentigo maligna

    PROGNOSIS
    93% 5-year survival 67% 5-year survival 38% 5-year survival < 1.5 mm thick 1.5-3.49 mm thick > 3 mm thick

    TREATMENT
    Breslow thickness - In situ - 1 mm - 1 2 mm - 2 4 mm Excision margin 0.5 - 1 cm 1 cm 2 cm 2 cm

    TERIMAKASIH

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