To accelerate biotechnology innovations, such as the development of lifesaving drug therapies, scientists strive to develop faster, more quantitative, and more widely available ways to observe biomolecules in living cells. Now, for the first time ever, NIST scientists have developed a new method that captures clear images of biomolecules in single live cells using infrared (IR) transmission imaging. The method has the potential to speed up advances in biomanufacturing, cell therapy development and drug development. Learn more about the imaging technique in our news story: https://lnkd.in/eWWD-i4k #Microscopy #Imaging #AnalyticalChemistry #Bioscience
National Institute of Standards and Technology (NIST)’s Post
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HumaTein™ a cell culture biomaterial supplement consisting of full native human ECM (Extracellular Matrix), useful for in vitro 4D bioprinting and cell culturing as well as clinical translational studies @RokitHealthcare https://buff.ly/4bGTZBs #organregeneration#skinregeneration
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https://www.youtube.com/
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Biophysical tools are powerful as they provide robust and reliable data, and can be applied to many stages across drug discovery workflows. Watch this on-demand webinar from Eurofins Cerep to learn how they use biophysics to carry out fragment screens and develop targeted protein degraders. You’ll get insight into how they: 💡 Used nanoDSF to confirm that their target protein, PIM3, was well-folded and intact so they could generate reproducible data 💡 Chose Spectral Shift technology over SPR after comparing binding data of a reference compound to the target 💡 Applied the same assay design to measure both low-affinity fragment binding and high-affinity PROTAC binding Watch the webinar: https://ow.ly/5SA150Rz3OE
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https://www.youtube.com/
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NIST scientists have introduced a groundbreaking method using infrared (IR) transmission imaging to capture clear images of biomolecules in single live cells. This innovative approach promises to significantly accelerate biotechnology advancements, including drug therapies and cell therapy development. By providing a more detailed view of biomolecular interactions in real-time, this method could enhance biomanufacturing processes and speed up the development of lifesaving treatments.