In a 2000 interview with Julie Strain in Entertainment Weekly, the interviewer said "You're nude quite a bit in this flick. Did you have any say in your 'toon physique?" Julie repulsed: "Absolutely. I went to Montreal to oversee the face structure and to make sure the character looked tall. Because I'm 6' 1". Sometimes, people draw me and you can tell the body is that of a 5' 8" person, and that really irritates me. There was a time when the face looked exactly like Minnie Driver. I was like 'Absolutely not!'"
While Julie and Germain pursue Tyler before his hyperspace jump, she passes a billboard which features Julie Strain herself on a magazine cover. It reads "Julie Strain: Six foot one and worth the climb". On the upper right hand corner of the billboard, it reads "Over 5 trillion sold".
Vlasta Vrana is the only returning actor from Heavy Metal (1981) (although he plays a different role).
FAKK2 stands for Federation Assigned Kinogenic Killzone to the second power.
After arriving at Neo-Calcutta, Julie is given the approach coordinates A-N-U-S-6-3-7-0. Shortly after that, she is given the visa file number U-R-F-U-K-D-8-8-1. (The "8-8-1" referring to the release date of the original film, August 1981.)