Contents Vol. 29, 2010

Vol. 29, 2010 Official Journal of the European Stroke Conference (ESC) Official Journal of the European Stroke Organisation (ESO) Founded 1991 by J. Bogousslavsky and M.G. Hennerici Editor-in-Chief Editorial Board M.G. Hennerici, Mannheim R.H. Ackerman, Boston, Mass. H. Adams, Iowa City, Iowa F. Aichner, Linz G. Auburger, Frankfurt/M. H. Bäzner, Stuttgart O. Benavente, Vancouver, B.C. J. Biller, Maywood, Ill. M. Borggrefe, Mannheim N. Bornstein, Tel Aviv M. Brainin, Tulln L.R. Caplan, Boston, Mass. H. Chabriat, Paris A. Chamorro, Barcelona A. Dávalos, Barcelona M.S. Dennis, Edinburgh H.-C. Diener, Essen U. Dirnagl, Berlin D. Droste, Luxembourg M. Fatar, Mannheim F. Fazekas, Graz J.M. Ferro, Lisbon M. Fisher, Worcester, Mass. N. Futrell, Murray, Utah A. Gass, Basel L.B. Goldstein, Durham, N.C. S.M. Greenberg, Boston, Mass. R. Haberl, München G.J. Hankey, Perth W.-D. Heiss, Köln M. Hommel, Grenoble D. Inzitari, Florence Associate Editors S. Davis, Melbourne J.P. Mohr, New York, N.Y. Y. Shinohara, Tokyo N. Venketasubramanian, Singapore Associate Co-Editors L. Hirt, Lausanne S. Meairs, Mannheim L.J. Kappelle, Utrecht M. Kaps, Giessen C. Kessler, Greifswald J.-S. Kim, Seoul P. Langhorne, Glasgow G.L. Lenzi, Rome E. Lesaffre, Leuven X.-F. Liu, Nanjing C.-Z. Lu, Shanghai K. Minematsu, Osaka K. Muir, Glasgow K. Niederkorn, Graz N. Nighoghossian, Lyon B. Norrving, Lund S.M. Oppenheimer, Baltimore, Md. S. Ricci, Città di Castello J. Röther, Minden P. Rothwell, Oxford A. Schwartz, Hannover S. Schwarz, Mannheim C. Stapf, Paris G.K. Steinberg, Stanford, Calif. T. Steiner, Heidelberg B. Tettenborn, St. Gallen K. Toyoda, Osaka S. Uchiyama, Tokyo N. Wahlgren, Stockholm S. Warach, Bethesda, Md. C. Weimar, Essen T. Yamaguchi, Osaka Basel Freiburg Paris London New York Bangalore Bangkok Shanghai Singapore Tokyo Sydney • • • • • • • • • • Contents Vol. 29, 2010 62 The Hyperdense Anterior Cerebral Artery Sign (HACAS) No. 1 1 Editorial – 20 Years Cerebrovascular Diseases Hennerici, M.G. (Mannheim) as a Computed Tomography Marker for Acute Ischemia in the Anterior Cerebral Artery Territory Jensen, U.R.; Weiss, M.; Zimmermann, P.; Jansen, O.; Riedel, C. (Kiel) 68 Polymorphism rs4934 of SERPINA3 and Sporadic Intracranial Aneurysms in the Chinese Population Review Liu, W.; Zhu, Y.; Ge, M.; Pang, Q. (Jinan); Yu, Y. (Beijing) 6 Stroke in Myopathies Finsterer, J.; Stöllberger, C. (Vienna) Original Papers Fracture in Patients with Previous Hemispheric Infarction and Nonrheumatic Atrial Fibrillation Sato, Y.; Honda, Y. (Tagawa); Jun, I. (Tokyo) 14 Baseline Diabetic Status and Admission Blood Glucose Were Poor Prognostic Factors in the EPITHET Trial De Silva, D.A. (Melbourne/Singapore); Ebinger, M. (Melbourne/Berlin); Christensen, S. (Melbourne); Parsons, M.W.; Levi, C. (Sydney); Butcher, K. (Edmonton); Barber, P.A. (Auckland); Bladin, C.; Donnan, G.A.; Davis, S.M. (Melbourne) Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET) Investigators 22 Cerebral White Matter Hyperintensities Predict Functional Stroke Outcome Liou, L.-M.; Chen, C.-F.; Guo, Y.-C.; Cheng, H.-L.; Lee, H.-L.; Hsu, J.-S.; Lin, R.-T.; Lin, H.-F. (Kaohsiung) 28 White Matter Lesions and Lacunar Infarcts Are Independently and Differently Associated with Brain Atrophy: The SMART-MR Study Appelman, A.P.A.; Vincken, K.L.; van der Graaf, Y.; Vlek, A.L.M.; Witkamp, T.D.; Mali, W.P.T.M.; Geerlings, M.I. (Utrecht) on behalf of the SMART Study Group 36 Obstructive Sleep Apnea Is Frequent in Patients with Hypertensive Intracerebral Hemorrhage and Is Related to Perihematoma Edema Pontes-Neto, O.M.; Fernandes, R.M.F.; Sander, H.H.; da Silva, L.A.T.; Mariano, D.C.; Nobre, F.; Simão, G.; de Araujo, D.B.; dos Santos, A.C.; Leite, J.P. (São Paulo) 43 Stroke Associated with Atrial Fibrillation – Incidence and Early Outcomes in the North Dublin Population Stroke Study Hannon, N.; Sheehan, O.; Kelly, L.; Marnane, M.; Merwick, A.; Moore, A.; Kyne, L.; Duggan, J.; Moroney, J.; McCormack, P.M.E.; Daly, L.; Fitz-Simon, N.; Harris, D.; Horgan, G.; Williams, E.B. (Dublin); Furie, K.L. (Boston, Mass.); Kelly, P.J. (Dublin) 50 Day-90 Acute Ischemic Stroke Outcomes Can Be Derived from Early Functional Activity Level Ovbiagele, B.; Saver, J.L. (Los Angeles, Calif.) 57 Transient Ischemic Attack after Tissue Plasminogen Activator: Aborted Stroke or Unnecessary Stroke Therapy? Uchino, K.; Massaro, L.; Hammer, M.D. (Pittsburgh, Pa.) © 2010 S. Karger AG, Basel Fax +41 61 306 12 34 E-Mail [email protected] www.karger.com 73 Long-Term Oral Anticoagulation Therapy and the Risk of Hip Access to full text and tables of contents, including tentative ones for forthcoming issues: www.karger.com/ced_issues 79 Antiplatelet Therapy in Combination with rt-PA Thrombolysis in Ischemic Stroke (ARTIS): Rationale and Design of a Randomized Controlled Trial Zinkstok, S.M.; Vermeulen, M.; Stam, J.; de Haan, R.J.; Roos, Y.B. (Amsterdam) 82 D-Dimers Predict Stroke Subtype when Assessed Early Isenegger, J.; Meier, N.; Lämmle, B.; Alberio, L.; Fischer, U.; Nedeltchev, K.; Gralla, J.; Kohler, H.-P.; Mattle, H.P.; Arnold, M. (Bern) 87 Characteristics of Patients with Target Magnetic Resonance Mismatch Profile: Data from Two Geographically and Racially Distinct Populations Bang, O.Y. (Seoul); Saver, J.L. (Los Angeles, Calif.); Lee, K.H.; Kim, G.M.; Chung, C.S.; Kim, S.J. (Seoul); Ovbiagele, B.; Alger, J.R.; Liebeskind, D.S. (Los Angeles, Calif.) for the UCLA-Samsung Stroke Collaborators Stroke Notes 95 Acute Spinal Cord Ischemia: Treatment with Intravenous and Intra-Arterial Thrombolysis, Hyperbaric Oxygen and Hypothermia Lee, K.; Strozyk, D.; Rahman, C.; Lee, L.K.; Fernandes, E.M.; Claassen, J.; Badjatia, N.; Mayer, S.A.; Pile-Spellman, J. (New York, N.Y.) 98 Acute Perfusion MR Imaging in a HaNDL-Like Syndrome Vallet, A.-E.; Desestret, V.; Tahon, F.; Cho, T-H.; Nighoghossian, N. (Lyon) Conference Report 101 Narrowing the Gap of Stroke Management between Developed and Developing Countries: Report of the Fifth International Stroke Summit, Nanjing, China, July 17–19, 2009 Xu, G.; Yin, Q.; Liu, X. (Nanjing) 103 ESO News No. 2 Original Papers 105 What Are the Consistent Predictors of Generic and Specific Post-Stroke Health-Related Quality of Life? Owolabi, M.O. (Ibadan) 111 Stroke in the Very Old: Incidence, Risk Factors, Clinical Features, Outcomes and Access to Resources – A 22-Year Population-Based Study Béjot, Y.; Rouaud, O.; Jacquin, A.; Osseby, G.-V.; Durier, J.; Manckoundia, P.; Pfitzenmeyer, P.; Moreau, T.; Giroud, M. (Dijon) Stroke Note 206 JAK2V617F Mutation Associated with Cerebral Venous Thrombosis: A Report of Five Cases Godeneche, G. (Poitiers); Gaillard, N. (Montpellier); Roy, L. (Poitiers); Mania, A.; Tondeur, S. (Montpellier); Chomel, J.C. (Poitiers); Lavabre, T.; Arquizan, C. (Montpellier); Neau, J.P. (Poitiers) 210 ESO News No. 3 122 Jugular Venous Reflux Affects Ocular Venous System in Transient Monocular Blindness Chung, C.-P. (Taipei); Hsu, H.-Y. (Taipei/Taichung); Chao, A-C. (Kaohsiung); Cheng, C.-Y.; Lin, S.-J.; Hu, H.-H. (Taipei) 130 Low Bone Mineral Density Is an Independent Risk Factor for Stroke and Death Nordström, A.; Eriksson, M. (Umeå); Stegmayr, B. (Umeå/Stockholm); Gustafson, Y.; Nordström, P. (Umeå) 137 Comparison of Telephone and Face-to-Face Assessment of the Modified Rankin Scale Janssen, P.M.; Visser, N.A.; Dorhout Mees, S.M.; Klijn, C.J.M.; Algra, A.; Rinkel, G.J.E. (Utrecht) 140 Is Moderate Atherosclerotic Stenosis in the Middle Cerebral Artery a Cause of or a Coincidental Finding in Ischemic Stroke? Klein, I.F.; Labreuche, J.; Lavallée, P.C.; Mazighi, M.; Duyckaerts, C.; Hauw, J.-J.; Amarenco, P. (Paris) 146 Relationship between Non-Specific Prescription Pill Adherence and Ischemic Stroke Outcomes Ovbiagele, B. (Los Angeles, Calif.); Campbell, S.; Faiz, A.; Chambless, L.E. (Chapel Hill, N.C.) VISP Study Investigators 154 Postendarterectomy Mortality in Octogenarians and Nonagenarians in the USA from 1993 to 1999 Lichtman, J.H.; Jones, S.B.; Wang, Y.; Watanabe, E.; Allen, N.B. (New Haven, Conn.); Fayad, P. (Omaha, Nebr.); Goldstein, L.B. (Durham, N.C.) 162 EEG Power Spectrum to Predict Prognosis after Hemicraniectomy for Space-Occupying Middle Cerebral Artery Infarction Diedler, J. (Heidelberg); Sykora, M. (Heidelberg/Bratislava); Jüttler, E. (Heidelberg/Berlin); Veltkamp, R.; Steiner, T.; Rupp, A. (Heidelberg) 170 Isolated Anterior Cerebral Artery Territory Infarction: Dissection as an Etiological Mechanism Sato, S.; Toyoda, K.; Matsuoka, H.; Okatsu, H.; Kasuya, J.; Takada, T.; Shimode, A.; Uehara, T.; Naritomi, H.; Minematsu, K. (Suita) 178 Electrocardiogram QT Interval Increases in Acute Stroke Mulcahy, J. (Taunton); Johnson, P.; James, M. (Exeter) 181 Proportion, Risk Factors and Outcome of Lacunar Infarction: A Hospital-Based Study in a Chinese Population Wu, B.; Lin, S.; Hao, Z. (Chengdu); Yang, J. (Chengdu/Nanjing); Xu, Y. (Zhengzhou); Wu, L. (Baotou); Zhang, S.; Liu, M. (Chengdu) 188 The Modified Rankin Scale in Acute Stroke Has Good Inter-Rater-Reliability but Questionable Validity Zhao, H.; Collier, J.M.; Quah, D.M.; Purvis, T.; Bernhardt, J. (Melbourne, Vic.) 194 Nicergoline Increases Serum Substance P Levels in Patients with an Ischaemic Stroke Nishiyama, Y.; Abe, A. (Tokyo/Chiba); Ueda, M.; Katsura, K.; Katayama, Y. (Tokyo) 199 Spatial Distension Variations Are Associated with Focal Atherosclerotic Plaques Graf, I.M.; Schreuder, F.H.B.M.; Mess, W.H.; Reneman, R.S.; Hoeks, A.P.G. (Maastricht) Contents Review 211 A Simultaneous EEG and Transcranial Doppler Technique to Investigate the Neurovascular Coupling in the Human Visual Cortex Rosengarten, B.; Kaps, M. (Giessen) Original Papers 217 The Spot Sign in Intracerebral Hemorrhage: The Importance of Looking for Contrast Extravasation Hallevi, H. (Tel Aviv); Abraham, A.T.; Barreto, A.D.; Grotta, J.C.; Savitz, S.I. (Houston, Tex.) 221 Symptom Progression or Fluctuation in Transient Ischemic Attack Patients Predicts Subsequent Stroke Nakajima, M. (Suita); Hirano, T. (Kumamoto); Naritomi, H.; Minematsu, K. (Suita) 228 Dynamic Cerebral Autoregulation Is Compromised Acutely following Mild Ischaemic Stroke but Not Transient Ischaemic Attack Atkins, E.R.; Brodie, F.G.; Rafelt, S.E.; Panerai, R.B.; Robinson, T.G. (Leicester) 236 Long-Term Outcomes of Ischemic Stroke Patients with Concurrent Intracranial and Extracranial Stenoses and Ischemic Heart Disease Man, B.L.; Fu, Y.P.; Chan, Y.Y.; Lam, W.; Hui, C.F.; Leung, W.H.; Mok, V.; Wong, K.S. (Hong Kong) 242 The –928 G/C and –362 G/C Single-Nucleotide Polymorphisms in the Promoter of MCP-1: Increased Transcriptional Activity and Novel Binding Sites Nyquist, P.; Zhang, J.; De Graba, T.J. (Bethesda, Md.) 248 High Prevalence of Peripheral Arterial Disease in Patients with Acute Ischaemic Stroke Topakian, R. (Linz); Nanz, S.; Rohrbacher, B.; Koppensteiner, R. (Vienna); Aichner, F.T. (Linz) on behalf of the OECROSS Study Group 255 Predictors of One-Year Disability and Death in Chinese Hospitalized Women after Ischemic Stroke Kong, F.-Y.; Tao, W.-D.; Hao, Z.-L.; Liu, M. (Chengdu) 263 Statin Use and Functional Outcome after Tissue Plasminogen Activator Treatment in Acute Ischaemic Stroke Miedema, I.; Uyttenboogaart, M.; Koopman, K. (Groningen); De Keyser, J. (Brussels); Luijckx, G.J. (Groningen) 268 Risk Factors for Aneurysmal Subarachnoid Hemorrhage in an Indian Population Koshy, L.; Easwer, H.V. (Thiruvananthapuram); Premkumar, S.; Alapatt, J.P. (Calicut); Pillai, A.M.; Nair, S.; Bhattacharya, R.N.; Banerjee, M. (Thiruvananthapuram) 275 Effect of Intravenous Tirofiban and Aspirin in Reducing Short-Term and Long-Term Neurologic Deficit in Patients with Ischemic Stroke: A Double-Blind Randomized Trial Torgano, G.; Zecca, B.; Monzani, V.; Maestroni, A.; Rossi, P.; Cazzaniga, M.; Manganaro, D.; Boiti, C.; Zilioli, E. (Milano); Borutti, G. (Voghera); Falaschi, F. (Pavia); Mandelli, C. (Milano) Cerebrovasc Dis Vol. 29, 2010 III 282 Filter-Protected versus Unprotected Carotid Artery Stenting: A Randomised Trial Macdonald, S. (Newcastle upon Tyne); Evans, D.H. (Leicester); Griffiths, P.D.; McKevitt, F.M.; Venables, G.S.; Cleveland, T.J.; Gaines, P.A. (Sheffield) 290 Atheromatous Plaques at the Origin of the Left Subclavian Artery in Patients with Ischemic Stroke Kuwashiro, T.; Toyoda, K.; Yoshimura, S.; Koga, M.; Naganuma, M.; Otsubo, R.; Konaka, K.; Uehara, T.; Naritomi, H.; Minematsu, K. (Suita) 297 Angiographic Pattern of Symptomatic Severe M1 Stenosis: Comparison with Presenting Symptoms, Infarct Patterns, Perfusion Status, and Outcome after Recanalization Choi, J.W.; Kim, J.K.; Choi, B.S.; Lim, H.-K.; Kim, S.J.; Kim, J.S.; Suh, D.C. (Seoul) 361 Factors Affecting Health-Related Quality of Life Assessed with the SF-36v2 Health Survey in Outpatients with Chronic-Stage Ischemic Stroke in Japan – Cross-Sectional Analysis of the OASIS Study Shinohara, Y. (Tokyo) for the OASIS Study Group 372 Variation in the C-Reactive Protein Gene Is Associated with Serum Levels of CRP in Patients with Acute Ischemic Stroke den Hertog, H.M.; van den Herik, E.G.; Dippel, D.W.J.; Koudstaal, P.J.; de Maat, M.P.M. (Rotterdam) 376 One-Year Case Fatality and Disability after Posterior Circulation Infarction in a Chinese Hospital-Based Stroke Study Tao, W.-D.; Kong, F.-Y.; Hao, Z.-L.; Lin, S.; Wang, D.-R.; Wu, B.; Liu, M. (Chengdu) 382 Perfusion-Weighted MRI as a Predictor of Clinical Outcomes Stroke Notes following Medullary Infarctions 304 Surgery after Anticoagulation in Stroke Patients with Nonatherosclerotic Internal Carotid Artery Thrombus: A Clinicopathological Case Series Bösel, J. (Berlin/Heidelberg); Kasper, A.S. (Berlin); Weichert, W. (Berlin/Heidelberg); Bohner, G.; Schreiber, S.J.; Endres, M. (Berlin) 307 Comparison of Automatic Intima Media Thickness Kim, S.J.; Ryoo, S.; Bang, O.Y.; Chung, C.-S.; Lee, K.H.; Kim, G.-M. (Seoul) 389 Dynamic Susceptibility Contrast Perfusion MRI Identifies Persistent Vessel Pathology in Acute Pontine Stroke Förster, A.; Ottomeyer, C.; Wolf, M.E.; Kern, R.; Griebe, M.; Gass, A.; Hennerici, M.G.; Szabo, K. (Mannheim) 395 Associations of Clinical Stroke Misclassification Measurement and Eye Balling (‘Clinical-Imaging Dissociation’) in Acute Ischemic Stroke Droste, D.W. (Münster/Luxembourg City); Schulte, V.; Schomacher, G.; Knapp, J.; Ringelstein, E.B. (Münster) Potter, G.; Doubal, F.; Jackson, C.; Sudlow, C.; Dennis, M.; Wardlaw, J. (Edinburgh) 309 Tako-Tsubo Syndrome: A Cardioembolic Cause of Brain Infarction Jabiri, M.Z.; Mazighi, M. (Paris); Meimoun, P. (Compiegne); Amarenco, P. (Paris) Stroke Notes 403 Different Patterns of Lateralization of Cognitive Functions in a Left-Handed Patient with Unilateral Right Middle Cerebral Artery Stroke Beaud Goetschmann, V.; Croquelois, A. (Lausanne) 311 ESO News 408 Positional Brain Ischemia with MCA Occlusion Successfully Treated with Extra-Intracranial Bypass Albanese, A.; Esposito, G.; Puca, A. (Rome); Tuttolomondo, A. (Palermo); Tirpakova, B.; Di Giuda, D.; Maira, G.; Di Lazzaro, V. (Rome) No. 4 410 Assessment of Pial Branches Using 7-Tesla MRI in Cerebral Original Papers 313 Role of Cardiac Multidetector Computed Tomography in Acute Ischemic Stroke: A Preliminary Report Ko, S.-B.; Choi, S.I.; Chun, E.J.; Ko, Y.; Park, J.-H.; Lee, S.-J. (Seoul); Lee, J. (Seongnam-si); Han, M.-K.; Bae, H.-J. (Seoul) 321 Variation in the Frequency of Intracerebral Haemorrhage and Ischaemic Stroke in China: A National, Multicentre, Hospital Register Study Wei, J.W.; Arima, H. (Sydney, N.S.W.); Huang, Y. (Beijing); Wang, J.-G. (Shanghai); Yang, Q. (Changsha); Liu, Z. (Shanghai); Liu, M. (Chengdu); Lu, C. (Shanghai); Heeley, E.L.; Anderson, C.S. (Sydney, N.S.W.) for the ChinaQUEST Investigators 328 Differential Pathophysiological Mechanisms of Stroke Evolution between New Lesions and Lesion Growth: Perfusion-Weighted Imaging Study Bang, O.Y.; Kim, G.M.; Chung, C.S.; Kim, S.J.; Kim, K.H.; Jeon, P. (Seoul); Saver, J.L.; Liebeskind, D.S. (Los Angeles, Calif.); Lee, K.H. (Seoul) 336 Wake-Up Stroke: Clinical and Neuroimaging Characteristics Silva, G.S. (Boston, Mass./São Paulo); Lima, F.O.; Camargo, E.C.S. (Boston, Mass.); Smith, W.S. (San Francisco, Calif.); Singhal, A.B.; Greer, D.M.; Ay, H.; Lev, M.H.; Harris, G.J.; Halpern, E.F.; Sonni, S. (Boston, Mass.); Koroshetz, W. (Bethesda, Md.); Furie, K.L. (Boston, Mass.) 343 Postcarotid Endarterectomy Improvement in Cognition Is Associated with Resolution of Crossed Cerebellar Hypoperfusion and Increase in 123I-Iomazenil Uptake in the Cerebral Cortex: A SPECT Study Chida, K.; Ogasawara, K.; Aso, K.; Suga, Y.; Kobayashi, M.; Yoshida, K.; Terasaki, K. (Morioka); Tsushina, E. (Hirosaki); Ogawa, A. (Morioka) Arterial Disease Song, H.-S. (Seoul); Kang, C.-K. (Incheon); Kim, J.S. (Seoul); Park, C.-A.; Kim, Y.-B. (Incheon); Lee, D.H.; Kang, D.-W.; Kwon, S.U. (Seoul); Cho, Z.-H. (Incheon) 412 Symmetrical Cerebral Arteriovenous Malformations in Bilateral Basal Ganglia Nagayama, K. (Tokyo); Kurita, H. (Tokyo/Saitama) 413 ESO News No. 5 Original Papers 415 Predicting Cognitive Dysfunctioning in Nondemented Patients Early after Stroke Jaillard, A.; Grand, S.; Le Bas, J.F.; Hommel, M. (Grenoble) 424 The Significance of Microembolic Signals and New Cerebral Infarcts on the Progression of Neurological Deficit in Acute Stroke Patients with Large Artery Stenosis Hao, Q.; Leung, W.H.; Leung, C.; Mok, C.T.; Leung, H.; Soo, Y.; Chen, X.Y.; Lam, W.; Wong, K.S. (Hong Kong) 431 Influence of Recanalization on Uric Acid Patterns in Acute Ischemic Stroke Hong, J.M. (Suwon); Bang, O.Y.; Chung, C.-S. (Seoul); Joo, I.S.; Gwag, B.J. (Suwon); Ovbiagele, B. (Los Angeles, Calif.) 352 Very Early Rehabilitation or Intensive Telemetry after Stroke: A Pilot Randomised Trial Langhorne, P.; Stott, D.; Knight, A. (Glasgow); Bernhardt, J. (Melbourne, Vic.); Barer, D. (Newcastle); Watkins, C. (Preston) IV Cerebrovasc Dis Vol. 29, 2010 Contents 440 Cerebral Venous Thrombosis with Nonhemorrhagic Lesions: 523 Navigating the Gray Zones of Stroke Management for a Clinical Correlates and Prognosis Graying Population Ferro, J.M.; Canhão, P. (Lisbon); Bousser, M.-G. (Paris); Stam, J. (Amsterdam); Barinagarrementeria, F. (Mexico City); Stolz, E. (Giessen) for the ISCVT Investigators Lee, M. (Los Angeles, Calif./Chiayi); Ovbiagele, B. (Los Angeles, Calif.) 446 Enlargement of Acute Intracerebral Hematomas in Patients on Long-Term Warfarin Treatment Kuwashiro, T. (Osaka); Yasaka, M. (Osaka/Fukuoka); Itabashi, R.; Nakagaki, H.; Miyashita, F.; Naritomi, H.; Minematsu, K. (Osaka) 454 The C677T Polymorphism of the Methylenetetrahydrofolate Reductase Gene Is Associated with Idiopathic Ischemic Stroke in the Young Mexican-Mestizo Population Isordia-Salas, I. (México City); Barinagarrementería-Aldatz, F. (Querétaro); Leaños-Miranda, A.; Borrayo-Sánchez, G.; Vela-Ojeda, J.; García-Chávez, J.; Ibarra-González, I.; Majluf-Cruz, A. (México City) 460 Preliminary Evidence of a High Risk of Bleeding on Aspirin plus Clopidogrel in Aspirin-Naïve Patients in the Acute Phase after TIA or Minor Ischaemic Stroke Geraghty, O.C.; Kennedy, J.; Chandratheva, A.; Marquardt, L.; Buchan, A.M.; Rothwell, P.M. (Oxford) 468 Fibro-Fatty Volume of Culprit Lesions in Virtual HistologyTM Intravascular Ultrasound Is Associated with the Amount of Debris during Carotid Artery Stenting Matsumoto, S.; Nakahara, I.; Higashi, T.; Iwamuro, Y.; Watanabe, Y.; Takezawa, M.; Murata, D.; Yokota, T.; Kira, J.; Yamada, T. (Fukuoka) 476 Impact of Prestroke Oral Anticoagulation on Severity and Outcome of Ischemic and Hemorrhagic Stroke in Patients with Atrial Fibrillation Audebert, H.J. (Berlin); Schenk, B.; Schenkel, J. (Munich); Heuschmann, P.U. (Berlin) 484 Mean Platelet Volume in the Early Phase of Acute Ischemic Stroke Is Not Associated with Severity or Functional Outcome Ntaios, G.; Gurer, O.; Faouzi, M.; Aubert, C.; Michel, P. (Lausanne) 490 Difference in Infarct Volume and Patterns between Cardioembolism and Internal Carotid Artery Disease: Focus on the Degree of Cardioembolic Risk and Carotid Stenosis Jung, J.-M.; Kwon, S.U.; Lee, J.-H.; Kang, D.-W. (Seoul) 497 Novel Hemostatic Factor Levels and Risk of Ischemic Stroke: The Atherosclerosis Risk in Communities (ARIC) Study Suri, M.F.K. (Minneapolis, Minn.); Yamagishi, K. (Minneapolis, Minn./Tsukuba); Aleksic, N. (Houston, Tex.); Hannan, P.J.; Folsom, A.R. (Minneapolis, Minn.) 503 Metabolic Syndrome Relates to Lacunar Stroke without White Matter Lesions: A Study in First-Ever Lacunar Stroke Patients Zhang, C.E.; van Raak, E.P.M.; Rouhl, R.P.W.; Lodder, J.; Staals, J.; Knottnerus, I.L.H.; van Oostenbrugge, R.J. (Maastricht) 508 Stroke and Action Slowing: Mechanisms, Determinants and Prognosis Value Godefroy, O.; Spagnolo, S.; Roussel, M.; Boucart, M.; (Lille/Amiens) Original Papers 528 Association of a Genetic Variant in the ALOX5AP with Higher Risk of Ischemic Stroke: A Case-Control, Meta-Analysis and Functional Study Domingues-Montanari, S.; Fernández-Cadenas, I.; del Rio-Espinola, A.; Corbeto, N. (Barcelona); Krug, T.; Manso, H. (Oeiras/Lisboa); Gouveia, L. (Lisboa); Sobral, J. (Oeiras/Lisboa); Mendioroz, M.; Fernández-Morales, J.; Alvarez-Sabin, J.; Ribó, M.; Rubiera, M.; Obach, V.; Martí-Fàbregas, J. (Barcelona); Freijo, M. (Bilbao); Serena, J. (Girona); Ferro, J.M. (Lisboa); Vicente, A.M.; Oliveira, S.A. (Oeiras/Lisboa); Montaner, J. (Barcelona) 538 Cerebral Perfusion Affects the Risk of Ischemia during Carotid Artery Stenting Jongen, L.M.; Hendrikse, J.; Moll, F.L.; Mali, W.P.T.M.; van der Worp, H.B. (Utrecht) 546 Peripheral Arterial Disease as an Independent Predictor for Excess Stroke Morbidity and Mortality in Primary-Care Patients: 5-Year Results of the getABI Study Meves, S.H. (Bochum); Diehm, C. (Karlsbad-Langensteinbach); Berger, K. (Münster); Pittrow, D. (Dresden); Trampisch, H.-J.; Burghaus, I. (Bochum); Tepohl, G. (Munich); Allenberg, J.-R. (Heidelberg); Endres, H.G. (Bochum); Schwertfeger, M.; Darius, H. (Berlin); Haberl, R.L. (Munich) for the getABI Study Group Comment 555 Stroke Risk Prediction beyond Classical Risk Factors: The Role of the Ankle-Brachial Index Sander, D. (Munich) Original Paper 557 Prevalence and Determinants of Cognitive Complaints after Aneurysmal Subarachnoid Hemorrhage Passier, P.E.C.A.; Visser-Meily, J.M.A.; van Zandvoort, M.J.E.; Post, M.W.M.; Rinkel, G.J.E. (Utrecht); van Heugten, C. (Maastricht) 564 c-Jun N-Terminal Kinase Pathway Inhibition in Intracerebral Hemorrhage Michel-Monigadon, D.; Bonny, C.; Hirt, L. (Lausanne) 571 Incidence and Clinical Correlation of Intracranial Hemorrhages Observed by 3-Tesla Gradient Echo T2*Weighted Images following Intravenous Thrombolysis with Recombinant Tissue Plasminogen Activator Harada, M.; Morita, N.; Uno, M.; Satomi, J.; Izumi, Y.; Asanuma, K.; Nishitani, H.; Kaji, R.; Nagahiro, S. (Tokushima) 576 Association of Platelet and Leukocyte Counts with Delayed Cerebral Ischemia in Aneurysmal Subarachnoid Hemorrhage Kasius, K.M.; Frijns, C.J.M.; Algra, A.; Rinkel, G.J.E. (Utrecht) 515 ESO News 584 Malignant Profile Detected by CT Angiographic Information Predicts Poor Prognosis despite Thrombolysis within Three Hours from Symptom Onset No. 6 517 Editorial Hennerici, M.G. (Mannheim) Invited Editorials 518 Sugar and NICE – Aggressive Hyperglycaemic Control in Ischaemic Stroke and What Can We Learn from Non-Neurological Intensive Glucose Control Trials in the Critically Ill? Kreisel, S.H. (Mannheim/Bielefeld); Alonso, A.; Szabo, K.; Hennerici, M.G. (Mannheim) Contents Puetz, V.; Dzialowski, I. (Dresden/Calgary, Alta.); Hill, M.D.; Steffenhagen, N.; Coutts, S.B.; O’Reilly, C.; Demchuk, A.M. (Calgary, Alta.) for the Calagary Study Group 592 Visual Assessment of Perfusion-Diffusion Mismatch Is Inadequate to Select Patients for Thrombolysis Campbell, B.C.V.; Christensen, S.; Foster, S.J.; Desmond, P.M. (Parkville, Vic.); Parsons, M.W. (Newcastle, N.S.W.); Butcher, K.S. (Edmonton, Alta.); Barber, P.A. (Auckland); Levi, C.R. (Newcastle, N.S.W.); Bladin, C.F. (Melbourne, Vic.); Donnan, G.A.; Davis, S.M. (Parkville, Vic.) for the EPITHET Investigators 597 Reliability of the ECASS Radiological Classification of Postthrombolysis Brain Haemorrhage: A Comparison of CT and Three MRI Sequences Renou, P. (Paris/Bordeaux); Sibon, I.; Tourdias, T.; Rouanet, F. (Bordeaux); Rosso, C.; Galanaud, D.; Drier, A.; Coudert, M.; Deltour, S.; Crozier, S.; Dormont, D.; Samson, Y. (Paris) Cerebrovasc Dis Vol. 29, 2010 V Comment Suppl. 1 605 T2*-Weighted Imaging Enables Excellent Interobserver Fiebach, J.B.; Bohner, G. (Berlin) Abstracts 15th Meeting of the European Society of Neurosonology and Cerebral Hemodynamics Madrid, Spain, May 22–25, 2010 Methodological Notes Guest Editors: J. Carneado-Ruiz (Madrid); F. Diaz Otero (Madrid); L. Cziba (Debrecen); D. Russell (Oslo) Concordance but Should Not Be Considered as Sole Gold Standard Imaging for Hemorrhagic Transformation Classification after Thrombolysis 607 What Does ‘Non-Inferior to’ Really Mean? A Clinician Thinking Out Loud Suppl. 2 Ricci, S. (Città di Castello) Abstracts 19th European Stroke Conference Barcelona, Spain, May 25–28, 2010 609 ESO News (available on CD-ROM only) 611 Author Index Vol. 29, 2010 614 Subject Index Vol. 29, 2010 616 Contents Vol. 29, 2010 S. 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