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The ethical problems of genetic engineering of human beings

1992, Journal of Medical Ethics

J Med Ethics: first published as 10.1136/jme.18.4.221 on 1 December 1992. Downloaded from http://jme.bmj.com/ on September 30, 2021 by guest. Protected by copyright. Journal of medical ethics, 1992, 18, 221-223 Book reviews The ethical problems of genetic engineering ofhuman beings fertilised ovum and in the gametes. The main part of the thesis addresses two questions. Firstly, is it morally acceptable (and compatible with the philosophy of St Thomas Aquinas) to intervene in human beings on such a fundamental level? The views ofvarious Willem Jacobus Eijk, 313 pages, Urbe, philosophers over the ages are 1990, 25.00 DF. Available from the considered, and Eijk discusses the author at: Seminarie Rolduc, 6464 EP, 'creation command' ('God said ... "Be fruitful, multiply, fill the earth and Kerkrade, Holland conquer it" ...') which some authors W J Eijk is a Catholic Christian interpret as a theological sanctioning of philosopher and he submitted this genetic engineering. He concludes that thesis for the degree of licence in one cannot entirely reject man's theology in Rome. It is written in rather intervention in human DNA on stilted English and this does detract theological or philosophical grounds, from the general flow of the text. The because genetic interventions in human references quoted are in various DNA done for therapeutic reasons are languages, including English, German, intrinsically good, as the faithful have Italian, French, Greek and Latin, but a always regarded it as their duty to source of translation for some of the combat evil (including disease). The question then evolves to become 'in Latin references is given. Two aspects of genetic engineering what situations is modification of are considered. Firstly, molecular human DNA allowed?'. genetic engineering or DNA This section is the one in which the recombinant technology, ie modifying influence of the teachings of the cloned genes and returning them to Catholic Church becomes most living cells; and secondly cellular apparent, particularly because the only genetic engineering or non-molecular acceptable method of procreation is via ways of altering the genetic material the conjugal act. Molecular genetic such as cellular fusion and engineering of somatic cells and their transplantation of complete nuclei. subsequent re-introduction into the The first part of the thesis provides a body (for the treatment of disease) is a brief explanation of the basic scientific form of autotransplantation and principles involved. In the section on therefore acceptable. Germline therapy methods of transmission of hereditary in fertilised human ova is regarded as diseases, statements which have been unacceptable, however, because it is oversimplified lead to inaccuracies: for connected with in vitro fertilisation. example, 'X-linked recessive gene Embryo experiments lacking any disorders occur exclusively in males'. possible therapeutic benefit for that Techniques of molecular and cellular embryo are found to be morally genetic engineering are described objectionable because of the respect briefly, followed by a concise and clear owed to the human individual from the statement on the list of conditions moment of conception. For the same which must be fulfilled if somatic gene reason, the cloning of a series of therapy of hereditary diseases is to be identical embryos in order for some to successful. The last part of the scientific be sacrificed for the diagnosis of gene introduction reviews methods of defects is unacceptable. In addition, the genetic engineering of germ line cells view that the fertilised egg is ensouled and their application in both the from the moment of conception means that the author concludes that genetic engineering in gametes rather than fertilised ova would be preferred, on condition that fertilisation would not be by artificial means. For Catholics grappling with the various complex issues discussed in this thesis, the extensive references and consideration of statements from the Vatican and the Bible will be useful. For non-Catholics involved in genetic engineering, however, the book will be interesting but rather restricted in its use, because those aspects of genetic engineering which are totally unacceptable to the Catholic Church (for example IVF and cloning) are not discussed in much detail, and other moral viewpoints in these complex fields are not really considered. FRANCES A FLINTER Division ofMedical and Molecular Genetics, UMDS, Guy's Hospital Naming the silences: God, medicine, and the problems of suffering Stanley Hauerwas, 154 pages + xiv, Grand Rapids, Michigan, 1990, William B Eerdmans Publishing Company, $9.95 This is a book by a professor of theological ethics which sets out to look at the problem of suffering, especially the suffering of children with leukaemia, from a theological point of view. In doing so, however, it also examines what is going on in the minds of the patients and the attitudes and actions of medical and nursing staff. The book can, therefore, be read at two levels, the theological and the practical.